Tormod Rogne, MD, PhD
Assistant Professor Adjunct of Epidemiology (Chronic Diseases)Cards
Contact Info
Yale School of Public Health
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, One Church Street, 6th Floor
New Haven, CT 06510
United States
About
Titles
Assistant Professor Adjunct of Epidemiology (Chronic Diseases)
Biography
Dr. Rogne is a medical doctor and researcher who focuses on perinatal epidemiology. Some of the ongoing projects includes evaluating how climate change affects pregnancy, the role of modifiable risk factors on reproductive health and adverse pregnancy outcomes, and how being born preterm affects the risk of cardiovascular and infectious diseases in adulthood. To tackle clinically relevant questions and providing robust results, he applies modern methods ranging from negative controls and inverse-probability weighting to genetic epidemiological methods and genome-wide association analyses. Dr. Rogne places emphasis on using high-quality data, in particular by use of data from population based cohorts and national registries.
Appointments
Chronic Disease Epidemiology
Assistant Professor AdjunctPrimary
Other Departments & Organizations
Education & Training
- Postdoctoral Scholar
- Norwegian University of Science and Technology, NTNU (2021)
- Fulbright Scholar
- Yale School of Public Health (2019)
- Residency
- Akershus University Hospital and Ski Municipality (2018)
- PhD
- Norwegian University of Science and Technology, NTNU (2016)
- MD
- Norwegian University of Science and Technology, NTNU (2015)
Research
Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0002-9581-7384- View Lab Website
Yale Center for Perinatal, Pediatric and Environmental Epidemiology
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Andrew DeWan, PhD, MPH
Xiaomei Ma, PhD
Joshua Warren, PhD
Kai Chen, PhD
Rong Wang, PhD
Zeyan Liew, PhD, MPH
Publications
2025
Examining socioeconomic differences in sepsis risk and mediation by modifiable factors: a Mendelian randomization study
Stensrud V, Rogne T, Flatby H, Mohus R, Gustad L, Nilsen T. Examining socioeconomic differences in sepsis risk and mediation by modifiable factors: a Mendelian randomization study. BMC Infectious Diseases 2025, 25: 739. PMID: 40410669, PMCID: PMC12103053, DOI: 10.1186/s12879-025-11130-y.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsSummary-level dataSocioeconomic differencesGenome-wide association studiesGenetic instrumentsEducational attainmentMendelian randomizationMR analysisStandard deviation increaseBias due to population stratificationOdds ratioPreventive factorsMR-Egger regressionExamined socioeconomic differencesMultivariable MR analysisEffect of smoking initiationAssociation studiesMendelian randomization studiesEffects of educational attainmentDeviation increaseYears of educationBody mass indexBackgroundEducational attainmentDynastic effectsMedian OREgger regressionA sibling study of the prenatal and perinatal risks for cerebral palsy
Zhuo H, Rogne T, Liew Z. A sibling study of the prenatal and perinatal risks for cerebral palsy. Pediatric Research 2025, 1-8. PMID: 40316681, DOI: 10.1038/s41390-025-04055-4.Peer-Reviewed Original ResearchAltmetricConceptsSibling comparison designCerebral palsyLow Apgar scoreMaternal pregnancy complicationsSibling designPerinatal factorsAssociated with CPApgar scoreComparison designPregnancy complicationsOdds ratioPreterm birthAttenuated to nullConfidence intervalsPre-pregnancy overweightLifestyle-related factorsCP riskSibling comparison studiesSibling-comparison designGestational ageMaternal cigarette smokingSingleton birthsCP etiologyInterpretation of findingsPre-pregnancyLong-term drought and risk of infant mortality in Africa: A cross-sectional study
Wang P, Rogne T, Warren J, Asare E, Akum R, Toure N, Ross J, Chen K. Long-term drought and risk of infant mortality in Africa: A cross-sectional study. PLOS Medicine 2025, 22: e1004516. PMID: 39888958, PMCID: PMC11785314, DOI: 10.1371/journal.pmed.1004516.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsRisk of infant mortalityInfant mortality riskCross-sectional studyInfant mortalityMortality riskIncreased risk of infant mortalityIncreased risk of neonatal mortalityIncreased riskRisk of neonatal mortalityHealth Surveys ProgramPost-neonatal mortalityCox regression modelsStatistically significant associationChild healthGlobal burdenNon-casesNeonatal mortalitySignificant associationImpact mortalityNon-exposureSurvival periodRegression modelsPregnancyMortalityHealthAdverse Pregnancy Outcomes and Coronary Artery Disease Risk: A Negative Control Mendelian Randomization Study
Rogne T, Gill D. Adverse Pregnancy Outcomes and Coronary Artery Disease Risk: A Negative Control Mendelian Randomization Study. Circulation 2025, 151: 193-195. PMID: 39804903, PMCID: PMC11740089, DOI: 10.1161/circulationaha.124.070509.Peer-Reviewed Original ResearchCitationsAltmetricUromodulin and Risk of Upper Urinary Tract Infections: A Mendelian Randomization Study
Liyanarachi K, Flatby H, Hallan S, Åsvold B, Damås J, Rogne T. Uromodulin and Risk of Upper Urinary Tract Infections: A Mendelian Randomization Study. American Journal Of Kidney Diseases 2025, 85: 570-576.e1. PMID: 39805364, DOI: 10.1053/j.ajkd.2024.11.007.Peer-Reviewed Original ResearchCitationsAltmetricConceptsUpper urinary tract infectionGenome-wide association studiesUrinary tract infectionOdds ratioMendelian randomizationTwo-sample Mendelian randomization analysisTwo-sample MR studyEuropean ancestryMichigan Genomics InitiativeInverse variance-weightedAssociation studiesMendelian randomization analysisMendelian randomization studiesAssociated with elevated oddsConfounding factorsSerum uromodulin levelsReduced riskTract infectionsUromodulin levelsSex-specific analysesAbstractText Label="PLAIN-LANGUAGE SUMMARYGenetic instrumentsHealth StudyUK BiobankUrinary uromodulinAssociations of Genetically Predicted NPR3 and NPR2 Perturbation and Preeclampsia Risk: A Two‐Sample Mendelian Randomization Analysis
de La Harpe R, Rogne T, Nyberg M, Cronjé H, Burgess S, Karhunen V, Gill D. Associations of Genetically Predicted NPR3 and NPR2 Perturbation and Preeclampsia Risk: A Two‐Sample Mendelian Randomization Analysis. International Journal Of Hypertension 2025, 2025: 9972031. PMID: 40406480, PMCID: PMC12097871, DOI: 10.1155/ijhy/9972031.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesMendelian randomizationTwo-sample Mendelian randomization analysisRisk of preeclampsiaTwo-sample MR analysisGenetic association estimatesGenetic instrumental variablesPreeclampsia riskMendelian randomization analysisFemale participantsC-type natriuretic peptideIndividual-level dataEffects of C-type natriuretic peptideGenetic instrumentsMR analysisUK BiobankRandomization analysisAssociation estimatesMR paradigmAssociation studiesGenetic variantsPregnancy complicationsProtective effects of C-type natriuretic peptideTwo-sampleInstrumental variables
2024
Autoimmune Diseases and Risk of Non‐Hodgkin Lymphoma: A Mendelian Randomisation Study
Shi X, Wallach J, Ma X, Rogne T. Autoimmune Diseases and Risk of Non‐Hodgkin Lymphoma: A Mendelian Randomisation Study. Cancer Medicine 2024, 13: e70327. PMID: 39506244, PMCID: PMC11540836, DOI: 10.1002/cam4.70327.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsRisk of non-Hodgkin lymphomaNon-Hodgkin's lymphomaAutoimmune diseasesMendelian randomisationType 1 diabetesAssociated with risk of non-Hodgkin lymphomaWeak instrument biasNon-Hodgkin lymphoma subtypesTwo-sample MRNon-Hodgkin lymphoma riskRisk factorsSusceptibility to type 1 diabetesMendelian randomisation studiesCohorts of European ancestryAssociated with riskNo significant associationPotential pleiotropyPotential risk factorsUK BiobankFinnGen studyNon-HodgkinHaematological malignanciesRandomised studyEuropean ancestrySignificant associationEarly-life lower respiratory tract infection (LRTI) and risk of school-age asthma - A population-based cohort study
Myklebust Å, Døllner H, Pape K, Rogne T, Risnes K. Early-life lower respiratory tract infection (LRTI) and risk of school-age asthma - A population-based cohort study. 2024, pa3131. DOI: 10.1183/13993003.congress-2024.pa3131.Peer-Reviewed Original ResearchHigh ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study
Rogne T, Wang R, Wang P, Deziel N, Metayer C, Wiemels J, Chen K, Warren J, Ma X. High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study. The Lancet Planetary Health 2024, 8: e506-e514. PMID: 38969477, PMCID: PMC11260908, DOI: 10.1016/s2542-5196(24)00121-9.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRisk of childhood acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLatino childrenNon-Latino white childrenAssociated with risk of adverse pregnancy outcomesCalifornia Cancer RegistryRisk of acute lymphoblastic leukemiaCalifornia birth recordsRisk of adverse pregnancy outcomesPre-pregnancy periodAssociated with riskBayesian meta-regressionNational Institutes of HealthCancer RegistryCases of childhood acute lymphoblastic leukemiaNational Center for Advancing Translational SciencesAdverse pregnancy outcomesAcute lymphoblastic leukemia casesInstitutes of HealthInvestigation of mechanistic pathwaysBirth recordsGestational weeks 8Pre-pregnancyA Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections
Flatby H, Ravi A, Liyanarachi K, Afset J, Rasheed H, Brumpton B, Hveem K, Åsvold B, DeWan A, Solligård E, Damås J, Rogne T. A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections. The Journal Of Infectious Diseases 2024, 230: e1334-e1343. PMID: 38713594, PMCID: PMC11646603, DOI: 10.1093/infdis/jiae231.Peer-Reviewed Original ResearchCitationsAltmetricConceptsGenome-wide association studiesMichigan Genomics InitiativeAssociation studiesUpper UTIMendelian randomizationMR analysisUpper urinary tract infectionRisk factorsPotential causal risk factorsCardiometabolic risk factorsModifiable risk factorsSex-stratified analysesCausal risk factorUrinary tract infectionGenome-wideFemale-only analysisGenetic lociPotential causal relationshipGenome InitiativeHealth StudyUK BiobankHLA-DQA2LociTract infectionsSmoking score
Academic Achievements & Community Involvement
Activities
activity The Journal of the Norwegian Medical Association
11/06/2017 - PresentPeer Review Groups and Grant Study SectionsAdvisorDetailsMedical research advisoractivity Research and teaching at Yale School of Public Health
07/01/2021 - PresentResearchDetailsNew Haven, CT, United Statesactivity Research collaboration with the Norwegian Institute of Public Health
09/25/2020 - PresentResearchDetailsOslo, Norwayactivity Research collaboration with the Norwegian University of Science and Technology, NTNU
08/18/2008 - PresentResearchDetailsTrondheim, Trøndelag, NorwayCollaboratorsAbstract/SynopsisResearch collaboration and location for MD/PhD education and training.
Honors
honor Fulbright Scholarship
12/07/2017International AwardDetailsNorwayhonor Tom Wilhelmsen Foundation’s Research Stipend
06/03/2013International AwardDetailsNorway
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Contacts
Yale School of Public Health
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, One Church Street, 6th Floor
New Haven, CT 06510
United States