Infectious Diseases
Laboratory Science
The Department of Epidemiology of Microbial Diseases has an established record of public health discovery through laboratory science. In the school’s first century, YSPH led the fight against poliomyelitis, housed the Arbovirus Research Unit which moved from the Rockefeller Foundation to Yale in 1964 (and was home to Nobel prize-winning scientist Max Theiler and other prominent scientists), as well as the WHO serum bank. Today, Yale is home to several modern laboratories that address vector-borne diseases transmitted by tsetse flies, ticks, mosquitoes and sand flies. In addition, our scientists are pursuing solutions to respiratory ailments, antibiotic resistance, diagnostic testing, vaccine development and infections related to STIs and intravenous drug use.
Recent Publications
2024
- Factors influencing adverse events following COVID-19 vaccination.Villanueva P, McDonald E, Croda J, Croda MG, Dalcolmo M, Dos Santos G, Jardim B, Lacerda M, Lynn DJ, Marshall H, Oliveira RD, Rocha J, Sawka A, Val F, Pittet LF, Messina NL, Curtis N. Hum Vaccin Immunother. 2024 Dec 31; 2024 Mar 6. PMID: 38445666.
- A scoping review of active, participant centred, digital adverse events following immunization (AEFI) surveillance of WHO approved COVID-19 vaccines: A Canadian immunization Research Network study.Serhan M, Psihogios A, Kabir N, Bota AB, Mithani SS, Smith DP, Zhu DT, Greyson D, Wilson S, Fell D, Top KA, Bettinger JA, Wilson K. Hum Vaccin Immunother. 2024 Dec 31; 2024 Feb 19. PMID: 38374618.
- Liver epigenomic signature associated with chronic oxidative stress in a mouse model of glutathione deficiency.Hong SH, Yu X, Zhu Y, Chen Y. Chem Biol Interact. 2024 Aug 1; 2024 Jun 1. PMID: 38830566.
- Self-injurious unnatural death among Veterans with HIV.Smith AC, Goulet JL, Vlahov D, Justice AC, Womack JA. AIDS. 2024 Aug 1; 2024 May 28. PMID: 38814683.
- COVID-19 Breakthrough Infection after Vaccination and Substance Use Disorders: A Longitudinal Cohort of People with and without HIV Receiving Care in the United States Veterans Health Administration.Soyer EM, McGinnis KA, Justice AC, Hsieh E, Rodriguez-Barradas MC, Williams EC, Park LS. AIDS Behav. 2024 Jul 24; 2024 Jul 24. PMID: 39046612.
- Uncertainty in tuberculosis clinical decision-making: An umbrella review with systematic methods and thematic analysis.Basile FW, Sweeney S, Singh MP, Bijker EM, Cohen T, Menzies NA, Vassall A, Indravudh P. PLOS Glob Public Health. 2024; 2024 Jul 23. PMID: 39042611.
- The impact of COVID-19 national lockdowns on drug-resistant tuberculosis in KwaZulu-Natal, South Africa: A spatial analysis.Harrington KRV, Gandhi NR, Shah NS, Naidoo K, Auld SC, Andrews JR, Brust JCM, Lutchminarain K, Coe M, Willis F, Campbell A, Cohen T, Jenness SM, Waller LA. Ann Epidemiol. 2024 Jul 20; 2024 Jul 20. PMID: 39038747.
- Longitudinal mass loads of phthalate esters in sewage sludge and their association with public health and social measures for COVID-19 control in Beijing.Sapkota S, Thapa B, Chen J, Zunong J, Asihaer Y, Li M, Ji X, Ding D, Li H, Ma B, Vermund SH, Shu M, Hu Y. Ecotoxicol Environ Saf. 2024 Jul 18; 2024 Jul 18. PMID: 39029222.
- Temporal and Racial/Ethnic Patterns of Social Engagement among Older Adults: Evidence from American Time Use Survey 2019 to 2022.Yu J, Huang W, Kahana E. J Appl Gerontol. 2024 Jul 18; 2024 Jul 18. PMID: 39023779.
- High silent prevalence of human herpesvirus 1 (HSV-1) infection affecting the indigenous reservation of the municipality of Dourados, Central-West Brazil.de Oliveira Bonfim FF, Villar LM, Croda J, Pereira JG, Guimarães ACS, da Silva SR, Maymone Gonçalves CC, Leonardo LFT, de Rezende Romeira GR, Cesar GA, Weis-Torres S, de Oliveira Landgraf de Castro V, Horta MA, Simionatto S, Motta-Castro ARC, de Paula VS. BMC Infect Dis. 2024 Jul 17; 2024 Jul 17. PMID: 39020287.
- Approaches for M. tuberculosis Transmission Inference Based on Genomic Data.Cohen T, Colijn C, Warren JL. Am J Respir Crit Care Med. 2024 Jul 17; 2024 Jul 17. PMID: 39018565.
- Upper respiratory Streptococcus pneumoniae colonization among working-age adults with prevalent exposure to overcrowding.Parker AM, Jackson N, Awasthi S, Kim H, Alwan T, Wyllie AL, Kogut K, Holland N, Mora AM, Eskenazi B, Riley LW, Lewnard JA. Microbiol Spectr. 2024 Jul 16; 2024 Jul 16. PMID: 39012111.
- Accelerated Bacille Calmette-Guérin reactions: More than meets the eye.Villanueva P, Crawford NW, Croda MG, Croda J, Dalcolmo M, Jardim BA, Jardim TAP, Marshall H, Prat-Aymerich C, Sawka A, Sharma K, Troeman D, Warris A, Wood N, Messina NL, Pittet LF, Curtis N. Heliyon. 2024 Jul 15; 2024 Jun 6. PMID: 39027494.
- Guided internet-based LGBTQ-affirmative cognitive-behavioral therapy: A randomized controlled trial among sexual minority men in China.Yi M, Li X, Chiaramonte D, Sun S, Pan S, Soulliard Z, Eisenstadt BE, Ljótsson B, Hagaman A, Pachankis J. Behav Res Ther. 2024 Jul 14; 2024 Jul 14. PMID: 39029333.
- Childhood Sexual Abuse and Compulsive Sexual Behavior Among Men Who Have Sex with Men Newly Diagnosed with HIV.Brown MJ, Osinubi MO, Amoatika D, Haider MR, Kirklewski S, Wilson P, Hansen NB. AIDS Behav. 2024 Jul 11; 2024 Jul 11. PMID: 38992227.
- Prepare Romania: study protocol for a randomized controlled trial of an intervention to promote pre-exposure prophylaxis adherence and persistence among gay, bisexual, and other men who have sex with men.Lelutiu-Weinberger C, Filimon ML, Zavodszky AM, Lixandru M, Hanu L, Fierbinteanu C, Patrascu R, Streinu-Cercel A, Luculescu S, Bora M, Filipescu I, Jianu C, Heightow-Weidman LB, Rochelle A, Yi B, Buckner N, Golub SA, van Dyk IS, Burger J, Li F, Pachankis JE. Trials. 2024 Jul 10; 2024 Jul 10. PMID: 38987812.
- Unveiling the Adoption and Barriers of Telemedicine in US Hospitals: A Comprehensive Analysis (2017-2022).Jiang JX, Ross JS, Bai G. J Gen Intern Med. 2024 Jul 10; 2024 Jul 10. PMID: 38985409.
- Two decades of molecular surveillance in Senegal reveal rapid changes in known drug resistance mutations over time.Ndiaye YD, Wong W, Thwing J, Schaffner SF, Brenneman KV, Tine A, Diallo MA, Deme AB, Sy M, Bei AK, Thiaw AB, Daniels R, Ndiaye T, Gaye A, Ndiaye IM, Toure M, Gadiaga N, Sene A, Sow D, Garba MN, Yade MS, Dieye B, Diongue K, Zoumarou D, Ndiaye A, Gomis JF, Fall FB, Ndiop M, Diallo I, Sene D, Macinnis B, Seck MC, Ndiaye M, Ngom B, Diedhiou Y, Mbaye AM, Ndiaye L, Sy N, Badiane AS, Hartl DL, Wirth DF, Volkman SK, Ndiaye D. Malar J. 2024 Jul 9; 2024 Jul 9. PMID: 38982475.
- Interactions between respiratory syncytial virus and Streptococcus pneumoniae in the pathogenesis of childhood respiratory infections: a systematic review.Besteman SB, Bogaert D, Bont L, Mejias A, Ramilo O, Weinberger DM, Dagan R. Lancet Respir Med. 2024 Jul 8; 2024 Jul 8. PMID: 38991585.
- Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study.Dyson ZA, Ashton PM, Khanam F, Chunga Chirambo A, Shakya M, Meiring JE, Tonks S, Karkey A, Msefula C, Clemens JD, Dunstan SJ, Baker S, Dougan G, Pitzer VE, Basnyat B, Qadri F, Heyderman RS, Gordon MA, Pollard AJ, Holt KE. Lancet Microbe. 2024 Jul 6; 2024 Jul 6. PMID: 38996496.
- e3SIM: epidemiological-ecological-evolutionary simulation framework for genomic epidemiology.Xu P, Liang S, Hahn A, Zhao V, Lo WT', Haller BC, Sobkowiak B, Chitwood MH, Colijn C, Cohen T, Rhee KY, Messer PW, Wells MT, Clark AG, Kim J. bioRxiv. 2024 Jul 2; 2024 Jul 2. PMID: 39005464.
- Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After SARS-CoV-2 Infection.Unger ER, Lin JS, Wisk LE, Yu H, L'Hommedieu M, Lavretsky H, Montoy JCC, Gottlieb MA, Rising KL, Gentile NL, Santangelo M, Venkatesh AK, Rodriguez RM, Hill MJ, Geyer RE, Kean ER, Saydah S, McDonald SA, Huebinger R, Idris AH, Dorney J, Hota B, Spatz ES, Stephens KA, Weinstein RA, Elmore JG. JAMA Netw Open. 2024 Jul 1; 2024 Jul 1. PMID: 39046739.
- Strategies for isoniazid preventive therapy in HIV-positive patients who consume alcohol.Savinkina A, Muyindike W, Hahn JA, Emenyonu NI, Fatch R, Ngabirano C, Adong J, Jacobson KR, Linas BP. Int J Tuberc Lung Dis. 2024 Jul 1. PMID: 38961548.
- Corrigendum to-"Identifying local foci of tuberculosis transmission in Moldova using a spatial multinomial logistic regression model" [eBioMedicine 102(2024) 105085].Lan Y, Crudu V, Ciobanu N, Codreanu A, Chitwood MH, Sobkowiak B, Warren JL, Cohen T. EBioMedicine. 2024 Jul; 2024 Jun 28. PMID: 38943727.
- Identification of hepatic steatosis among persons with and without HIV using natural language processing.Torgersen J, Skanderson M, Kidwai-Khan F, Carbonari DM, Tate JP, Park LS, Bhattacharya D, Lim JK, Taddei TH, Justice AC, Lo Re V 3rd. Hepatol Commun. 2024 Jul 1; 2024 Jun 19. PMID: 38896066.