- August 28, 2023
Xylazine presents new challenges for emergency treatment of overdose
- August 22, 2023
Opara receives $3.5 million grant to curb urban drug use, involve youth in research
- July 19, 2023
Hepatitis cases and heart valve infection deaths tied to early OxyContin marketing
- February 26, 2023
Saving Lives: YSPH students receive training on overdose response
Substance Use
The use of alcohol, tobacco and other drugs has long been associated with a range of public health problems, including cancer, chronic lung and liver disease, sexually transmitted and blood-borne infections and mental health. Our school's researchers are studying emerging trends associated with vaping, legalized recreational marijuana, and the U.S. opioid crisis, which now claims about 50,000 lives annually.
The availability of illicitly produced synthetic opioids has increased dramatically since 2013, worsening the public health crisis. In response to this crisis, research at the Yale School of Public Health includes epidemiological and geospatial analyses of opioid-involved fatalities in Connecticut and elsewhere in the United States that include assessing the potential public health benefits of expanded access to naloxone. Additionally, research is being conducted assessing the role of expedited referral to medication-based treatment through harm-reduction organizations and emergency departments in treating the underlying opioid-use disorder.
Other YSPH research includes:
- Factors that may contribute to risk of non-fatal opioid overdoses
- The role of mental health, stigma and discrimination in substance use
- How to integrate behavioral health care for substance use problems into primary care
- Strategies for limiting the harms of substance use, and more foundational studies of the causes or impacts of inadequately treated substance use or mental illness
- Using behavioral health economics to develop programs to promote risk-reduction behaviors
- Potential eHealth applications as effective tools for treating tobacco- and substance-use disorders
- The economics of substance abuse including lost productivity, cost-effectiveness of treatments, social costs and policy, and drivers behind key disparities
- The role of substance use in co-morbidities such as cancer and HIV
- Tobacco and e-cigarette control
- The impact of the COVID-19 pandemic on prevention for, treatment of, and individual and community harms associated with substance use disorders
Recent Publications
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Journal of Substance Abuse Treatment
Changes in methadone program practices and fatal methadone overdose rates in Connecticut during COVID-19 -
APA PsycNet
The role of emotion dysregulation in the association between substance use stigma and depressive symptoms among trauma-exposed, substance-using individuals. -
Journal of Ethnicity in Substance Abuse
Sociopolitical control as a mediator between ethnic identity and social support on 30-day drug use among black girls -
Journal of the National Cancer Institute
Predictors of Chronic Opioid Use: A Population-Level Analysis of North Carolina Cancer Survivors Using Multi-Payer Claims
Centers and other resources
YSPH Substance Use/Alcohol/Tobacco 2022 Research Highlights
- Chemico-Biological InteractionsLiver metabolomics identifies bile acid profile changes at early stages of alcoholic liver disease in mice
- JAMA Health ForumEstimated Prevalence of Smoking and Smoking-Attributable Mortality Associated with Graphic Health Warnings on Cigarette Packages in the US From 2022 to 2100
- The New England Journal of MedicineThe E-Cigarette Flavor Debate — Promoting Adolescent and Adult Welfare