- July 08, 2025
How Exercise Increases Cancer Survival
- May 14, 2025
National Cancer Research Month with Dr. Jeffrey Townsend
- May 06, 2025
Genetic Test Underused in Cancer Care
- May 05, 2025
Older Women May Benefit From Regular Mammograms
Cancer
More people today die from cancer than from almost any other cause in the world. The challenges posed by cancer are immense and top scientists at the Yale School of Public Health are committed to reducing its toll.
The departments of Chronic Disease Epidemiology, Biostatistics and Health Policy and Management are heavily focused on a wide variety of cancer-related research, and the Department of Environmental Health Sciences is renowned for novel approaches to the study of how environmental exposures affect health outcomes. From key partnerships with the Yale Cancer Center to collaborative efforts locally and globally, YSPH scientists are taking significant steps toward preventing and treating a wide range of cancers. Today, research in cancer and other chronic diseases encompasses interdisciplinary teams committed to understanding cancer causation and etiology, prevention, screening and early detection, risk factors, environmental exposures, social determinants of health and survival.
A variety of technologies and approaches are used to detect mechanisms and characteristics of the many different types of cancer, including genomics, metabolomics, social and behavioral effects, evolutionary biology, biostatistical methodology and study design, and outcomes research.
The Yale School of Public Health maintains biospecimens and data from thousands of individuals in more than a dozen studies that can be made applied to future research. It also has partnerships with numerous international cancer researchers, and is the home of leading experts in clinical trial design and data management, and genomic and metabolic centers.
Recent Publications
- Barriers and facilitators to a combined strategy of HPV vaccination and cervical cancer screening among Mexican women.León-Maldonado L, Cabral A, Pages G, Brown B, Allen-Leigh B, Lazcano-Ponce E, Xavier Bosch F, Spiegelman D, Torres-Ibarra L, Hernández-Ramírez RU, Egger E, Rivera-Paredez B, Salmerón J. Hum Vaccin Immunother. 2025 Dec; 2025 Apr 2. PMID: 40172917.
- Factors Associated With Timely Receipt of Colposcopy After Abnormal Cervical Cancer Screening.Patel AV, Qiu W, Sartor R, Wilcox M, Jones BA, Hernandez-Ramirez RU, Tang W, Megiel S, Girgis A, Foster J, Tong G, Spiegelman D, Sheth SS. J Low Genit Tract Dis. 2025 Jul 16; 2025 Jul 16. PMID: 40631578.
- GWAS meta-analysis identifies five susceptibility loci for endometrial cancer.Ramachandran D, Wang X, Laisk T, Zheng Y, Ingold N, Canson DM, Kho PF, Naumann BJ, Chapman CJ, Bousset K, Krause AV, Schürmann P, Wieland B, Hanel P, Hülse F, Häfner N, Runnebaum I, Dubrowinskaja N, Turmanov N, Yugay T, Yessimsiitova ZB, Amant F, Annibali D, Beckmann MW, Bodelon C, Buchanan DD, Chen C, Clarke MA, Cook LS, De Vivo I, De Wispelaere W, Du M, Easton DF, Emons J, Fasching PA, Friedenreich CM, Gallagher G, Giles GG, Goode EL, Harris HR, Hunter DJ, Kolin DL, Kraft P, Lacey JV, Lambrechts D, Lu L, Mutter GL, Naduparambil J, O'Connell K, Patel AV, Pharoah PDP, Rebbeck TR, Ricceri F, Risch HA, Ruebner M, Sacerdote C, Scott RJ, Setiawan VW, Shu XO, Southey MC, Tham E, Tomlinson I, Turman C, Wentzensen N, Xu W, Yu H, Zheng W, Spurdle AB, Yarden Y, Mägi R, Hillemanns P, Glubb DM, Dörk T, O'Mara TA. EBioMedicine. 2025 Jul 8; 2025 Jul 8. PMID: 40633141.
- Joint modeling of mixed outcomes using a rank-based sparse neural network.Xue J, Xu Y, Li J, Ma S, Fang K. J Biomed Inform. 2025 Jul 5; 2025 Jul 5. PMID: 40623577.
- Extending Cancer Survival with Exercise - Time for Oncology to Act.Irwin ML. N Engl J Med. 2025 Jul 3. PMID: 40601943.
- Distribution of copy number alterations and impact of chromosome arm call thresholds for meningioma.Patel RV, Ghosh HS, Meredith DM, Ryall S, Claus EB, Beroukhim R, Ligon AH, Santagata S, Bi WL. Nat Commun. 2025 Jul 2; 2025 Jul 2. PMID: 40603304.
- Lessons learned from aldehyde dehydrogenases as non-P450 aldehyde-oxidizing enzymes: implications for the 'exposome' and human health.Lisgara A, Thompson DC, Nebert DW, Vasiliou V. Expert Opin Drug Metab Toxicol. 2025 Jul 2; 2025 Jul 2. PMID: 40591371.
- Robust Transfer Learning for High-Dimensional GLM Using γ -Divergence With Applications to Cancer Genomics.Xu F, Ma S, Zhang Q, Xu Y. Stat Med. 2025 Jul. PMID: 40662636.
- Exercise effects on symptoms of depression and anxiety vary by patient, clinical, and intervention characteristics in cancer survivors: Results from pooled analyses of individual participant data of 26 RCTs.Kenkhuis MF, Doorenbos M, Mast IH, Aaronson NK, van Beurden M, Bohus M, Courneya KS, Daley AJ, Galvão DA, Goedendorp MM, van Harten WH, Hayes SC, Hiensch AE, Irwin ML, Kersten MJ, Knoop H, May AM, McConnachie A, van Mechelen W, Mutrie N, Newton RU, Nollet F, Oldenburg HS, Schmidt ME, Schmitz KH, Schulz KH, Sonke GS, Steindorf K, Stuiver MM, Taaffe DR, Thorsen L, Velthuis MJ, Wiskemann J, Mesters I, Ulrich CM, van Vulpen JK, Custers JAE, Buffart LM. Support Care Cancer. 2025 Jul 1; 2025 Jul 1. PMID: 40591016.
- Associations between colonization with Helicobacter pylori and risk of gastrointestinal tract cancers: An umbrella review of meta-analyses.Paiva Prudente T, Mezaiko E, Nunes Pereira Oliva H, Yamamoto-Silva FP, Santos de Freitas Silva B, Oliveira Oliva I, Risch H. Eur J Clin Invest. 2025 Jul; 2025 Jan 29. PMID: 39878420.
- Optimizing participant and community engagement in cancer genomic sequencing research.Crossnohere NL, Schuster ALR, Blair CK, Bland H, Carpten JD, Claus EB, Colditz GA, Diehl D, Ding L, Drake BF, Fields RC, George S, Janeway K, Kim H, Lenz HJ, Mack JW, Ricker C, Stern MC, Sussman A, Trent J, Van Allen E, Verhaak R, Willman C, Bridges JFP, Mishra SI, Kwan BM. Genet Med. 2025 Jun 11; 2025 Jun 11. PMID: 40517303.
- Clinicopathologic Features of Untreated Colorectal Cancer with Acellular Mucin-Only Lymph Nodes.Luo W, Hu S, Riahi IR, Wang HL, Shaker N, Abukhiran I, Wang T, Polydorides AD, Akinsanya A, González IA, Hagen C, Graham RP, Lisovsky M, Longacre TA, Challa B, Chen W, Harter D, Beech C, Najibi M, Cao W, Lee M, Lagana SM, Liao X, Setia N, Westbrook LM, Chandan VS, Choi WT, Ding X, Gonzalez RS, Gopal P, Lee H, Navale P, Liu X, Panarelli NC, Yang Z, Drage MG, Song Z, Li F, Nagtegaal ID, Zhang X. Mod Pathol. 2025 Jun 11; 2025 Jun 11. PMID: 40513988.
- Mortality Outcomes for Survivors of Cancer With Food Insecurity in the US.Lin JC, Sun J, Yan R, Wang LS, McCarthy AM, Tong G, Aysola J. JAMA Health Forum. 2025 Jun 7; 2025 Jun 7. PMID: 40540285.
- Celecoxib as a potential treatment for hepatocellular carcinoma in populations exposed to high PFAS levels.Sun B, Zhao Y, Yang S, Li X, Li N, Wang Y, Han Q, Liu X, Tu Q, Zheng J, Zhang X. J Hazard Mater. 2025 Jun 5; 2025 Feb 13. PMID: 39955994.
- Risk of Thyroid Tumors With GLP-1 Receptor Agonists: A Retrospective Cohort Study.Morales DR, Bu F, Viernes B, DuVall SL, Matheny ME, Simon KR, Falconer T, Richter LR, Ostropolets A, Lau WCY, Man KKC, Chattopadhyay S, Mathioudakis N, Minty E, Nishimura A, Sun F, Yin C, Seager SL, Chai Y, Zhou JJ, Lu Y, Reyes C, Pistillo A, Duarte-Salles T, Blacketer C, Schuemie MJ, Ryan PB, Krumholz HM, Hripcsak G, Khera R, Suchard MA. Diabetes Care. 2025 Jun 4; 2025 Jun 4. PMID: 40465422.
- Competing Subclones and Fitness Diversity Shape Tumor Evolution Across Cancer Types.Chen H, Shu J, Mudappathi R, Li E, Wang P, Bergsagel L, Yang P, Sun Z, Zhao L, Shi C, Townsend JP, Maley C, Liu L. bioRxiv. 2025 Jun 3; 2025 Jun 3. PMID: 40502073.
- Biomarker-Specific Survival and Medication Cost for Patients With Non-Small Cell Lung Cancer.Tan J, Yang SC, Dinan MA, Chiang AC, Gross CP, Wang SY. JAMA Netw Open. 2025 Jun 2; 2025 Jun 2. PMID: 40493365.
- Contribution of chronic conditions to mortality: Differences by race and ethnicity.Elman MR, Quiñones AR, McAvay GJ, Vander Wyk B, Nagel CL, Allore HG. Aging Health Res. 2025 Jun; 2025 Apr 23. PMID: 40575585.
- Psychosocial Experiences of African American Parents of Children With Cancer.Eche-Ugwu IJ, Aronowitz T, Broden EG, Merz A, White-Hammond GE, Umaretiya PJ, Bullock K, Brock K, Johnston EE, Wolfe J, Feraco AM. Pediatrics. 2025 Jun 1. PMID: 40398876.
- Twenty-five years without progress: The enduring challenge of soft tissue sarcomas.Hardy NJ, Frej KBH, Nkansah R, Olino K, Deshpande H, Ma X, Trent JC, Costa P. Cancer. 2025 Jun 1. PMID: 40396557.
- Adoption of Broad Genomic Profiling in Patients With Cancer.Wang X, Rothen J, Huang S, Long JB, Soulos PR, Goldberg SB, Mamtani R, Presley CJ, Kunst N, Ma S, Wang SY, Gross CP, Dinan MA. JAMA Oncol. 2025 Jun 1. PMID: 40244595.
- Developing a digital video to support lung cancer screening in diverse populations.Lindsay M, Odole IP, Belliveau O, Abujarad F, Gross CP, Richman IB. PEC Innov. 2025 Jun; 2025 Mar 17. PMID: 40212805.
- Off-Label Use of First-Line Immunotherapy for Metastatic Renal Cell Carcinoma.McManus HD, Long JB, Westvold SJ, Leapman MS, Hurwitz ME, Mitchell AP, Pollack CE, Gross CP, Dinan MA. Clin Genitourin Cancer. 2025 Jun; 2025 Mar 15. PMID: 40186898.
- A robust multiplex-DIA workflow profiles protein turnover regulations associated with cisplatin resistance and aneuploidy.Salovska B, Li W, Bernhardt OM, Germain PL, Wang Q, Gandhi T, Reiter L, Liu Y. Nat Commun. 2025 May 30; 2025 May 30. PMID: 40447611.
- Cutaneous lupus features specialized stromal niches and altered retroelement expression.Gehlhausen JR, Kong Y, Baker E, Ramachandran S, Koumpouras F, Ko CJ, Vesely M, Little AJ, Damsky W, King B, Iwasaki A. J Invest Dermatol. 2025 May 21; 2025 May 21. PMID: 40409678.
- Breast Cancer Diagnosis and Management in an Area of Protracted Conflict: A Case Series from Northwest Syria.Hamze M, Alawa J, Alahdab F, Al-Shemali A, Alhussein AN, Arab NMA, Galal B, Debel J, Jemo A, Khalil M, Chagpar A, Atassi B, Khoshnood K, Abbara A. Avicenna J Med. 2025 Jan; 2025 May 19. PMID: 40395698.
- Canonical amplifications and CDKN2A/B loss refine IDH1/2-mutant astrocytoma prognosis.Ghosh HS, Patel RV, Claus EB, Gonzalez Castro LN, Wen PY, Ligon KL, Meredith DM, Bi WL. Neuro Oncol. 2025 May 15. PMID: 39584448.
- Breastfeeding attributable fraction of triple negative breast cancer in the US.Chehayeb RJ, Odzer N, Albany RA, Ferrucci L, Sarpong D, Perez-Escamilla R, Lewis JB, Phipps AI, Meisner A, Pusztai L. NPJ Breast Cancer. 2025 May 7; 2025 May 7. PMID: 40328734.
- Accelerated Aging in Cancer and Cancer Treatment: Current Status of Biomarkers.Abraham S, Parekh J, Lee S, Afrin H, Rozenblit M, Blenman KRM, Perry RJ, Ferrucci LM, Liu J, Irwin ML, Lustberg M. Cancer Med. 2025 May. PMID: 40322791.
- Sex-specific effects of exogenous asparagine on colorectal tumor growth, 17β-estradiol levels, and aromatase.Aladelokun O, Benitez K, Wang Y, Jain A, Berardi D, Maroun G, Shen X, Roper J, Gibson J, Sumigray K, Khan SA, Johnson CH. Pharmacol Res. 2025 May; 2025 Apr 12. PMID: 40228761.
- Perinatal Exposures to Ambient Fine Particulate Matter and Outdoor Artificial Light at Night and Risk of Pediatric Papillary Thyroid Cancer.Deziel NC, Wang R, Warren JL, Dinauer C, Ogilvie J, Clark CJ, Zhong C, Wiemels JL, Morimoto L, Metayer C, Ma X. Environ Health Perspect. 2025 May; 2025 May 29. PMID: 40209106.
- Uncovering Structurally Differential Care: Pediatric Oncology Nurses' Perspectives Caring for African American Families.Eche-Ugwu IJ, Aronowitz T, Broden EG, Merz A, Vernadakis A, Bullock K, Wolfe J, Feraco AM. J Pain Symptom Manage. 2025 May; 2025 Feb 5. PMID: 39920978.
- Primary Tumors of the Brain and Central Nervous System in Adults and Children in Sub-Saharan Africa: Protocol for a Scoping Review.Al-Fikri AAB, Alhammadi M, Arum C, Kaur M, Del Biondo K, Bani I, Mudenda V, Vermund SH. JMIR Res Protoc. 2025 Apr 24; 2025 Apr 24. PMID: 40273436.
- Long-term mortality trends among individuals with tuberculosis: a retrospective cohort study of individuals diagnosed with tuberculosis in Brazil.Kim S, Pelissari DM, Harada LO, Sanchez M, Oliveira PB, Johansen FDC, Maciel ELN, Cohen T, Castro MC, Menzies NA. Clin Infect Dis. 2025 Apr 18; 2025 Apr 18. PMID: 40249758.
- Fish consumption and gastric cancer within the Stomach cancer Pooling (StoP) Project.Franchi C, Ardoino I, Mandelli S, Patel L, Pelucchi C, Bonzi R, Camargo MC, Rabkin CS, Liao LM, Sinha R, Johnson KC, Hu J, Zhang ZF, Palli D, Ferraroni M, Negri E, Turati F, Yu GP, Lunet N, Morais S, López-Carrillo L, Tsugane S, Hidaka A, Malekzadeh R, Zaridze D, Maximovitch D, Vioque J, Gonzalez-Palacios S, Ward MH, Aragonés N, Castaño-Vinyals G, Curado MP, Dias-Neto E, Hamada GS, Hernández-Ramirez RU, Pakseresht M, Pourfarzi F, Mu L, Lagiou A, Lagiou P, López-Cervantes M, Dolci A, Boccia S, Pastorino R, Boffetta P, D'Avanzo B, La Vecchia C. Sci Rep. 2025 Apr 16; 2025 Apr 16. PMID: 40240417.
- The impact of Indigenous American-like ancestry on risk of acute lymphoblastic leukemia in Hispanic/Latino children.Langie J, Chan TF, Yang W, Kang AY, Morimoto L, Stram DO, Mancuso N, Ma X, Metayer C, Lupo PJ, Rabin KR, Scheurer ME, Wiemels JL, Yang JJ, de Smith AJ, Chiang CWK. medRxiv. 2025 Apr 10; 2025 Apr 10. PMID: 39867407.
- Screening History, Stage at Diagnosis, and Mortality in Screen-Detected Breast Cancer.Huang S, Westvold SJ, Soulos PR, Fan J, Winer EP, Zhan H, Lustberg MB, Lewin J, Robinson TJ, Dinan MA. JAMA Netw Open. 2025 Apr 1; 2025 Apr 1. PMID: 40232715.
- Phase II Trial of Chemotherapy, Cetuximab, and Erlotinib in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck.Bhatia A, Mehra R, Bauman J, Khan SA, Wei W, Neumeister V, Sandoval-Schaefer T, Alpaugh RK, Lango M, Rimm DL, Ridge JA, Burtness B. Head Neck. 2025 Apr 1; 2025 Apr 1. PMID: 40166973.
- Precision projections of the delay of resistance mutations in non-small cell lung cancer via suppression of APOBEC.Nousias O, Mandell JD, Anderson KS, Townsend JP. Lung Cancer. 2025 Apr; 2025 Mar 13. PMID: 40090261.
- Urology on a changing planet: links between climate change and urological disease.Cole AP, Qian Z, Gupta N, Leapman M, Zurl H, Trinh QD, Sherman JD, Loeb S, Iyer HS. Nat Rev Urol. 2025 Apr; 2025 Jan 28. PMID: 39875561.
- BPI25-017: A Novel Integrated Classification Schema for Molecular Findings by Potential Clinical Actionability: A Tool for Assessment of Real-World Cancer Care in the Targeted Therapy Era.Wang X, Long JB, Rothen J, Soulos PR, Robinson TJ, Presley CJ, Goldberg SB, Mamtani R, Wang SY, Kunst N, Ma S, Huang S, Gross CP, Dinan MA. J Natl Compr Canc Netw. 2025 Mar 28; 2025 Mar 28. PMID: 40154428.
- BPI25-005: Molecular Biomarker Testing Patterns and Turn-Around Time in US Patients With Advanced Non-Small Cell Lung Cancer.Wang X, Lee D, Yang SC, Li Y, Soulos PR, Gross CP, Wang SY, Chiang AC. J Natl Compr Canc Netw. 2025 Mar 28; 2025 Mar 28. PMID: 40154384.
- Glioma mutational signatures associated with haloalkane exposure are enriched in firefighters.Cannataro VL, Bracci PM, Taylor JW, McCoy L, Rice T, Hansen HM, Heffernan AE, Wiemels J, Wiencke J, Wrensch M, Claus EB. Cancer. 2025 Mar 15. PMID: 40059488.
- Perinatal exposure to ambient fine particle air pollution and risk of childhood ewing sarcoma in a population-based case-control study in California (1988-2015).Clark CJ, Wang R, Wiemels JL, Metayer C, Deziel NC, Ma X. Environ Health. 2025 Mar 7; 2025 Mar 7. PMID: 40055781.
- Long COVID has variable incidence and clinical presentations: our 6-country collaborative study.Szabo S, Muzyka I, Muller V, Szabo AJ, Szijártó A, Gyires K, Doczi T, Janszky J, Stengel A, Göpel S, Trichopoulou A, Diaz R, Camacho N, Malatinszky G, Lambrecht N, Zayachkivska O. Inflammopharmacology. 2025 Mar; 2025 Feb 21. PMID: 39982603.
- Quality of gastrointestinal surgical oncology care according to insurance status.Butensky SD, Kerekes D, Bakkila BF, Billingsley KG, Ahuja N, Johnson CH, Khan SA. J Gastrointest Surg. 2025 Mar; 2025 Jan 10. PMID: 39800081.
- Risks of grade reclassification among patients with Gleason grade group 1 prostate cancer and PI-RADS 5 findings on prostate MRI.Sundaresan VM, Webb L, Rabil M, Golos A, Sutherland R, Bailey J, Rajwa P, Seibert TM, Loeb S, Cooperberg MR, Catalona WJ, Sprenkle PC, Kim IY, Leapman MS. Urol Oncol. 2025 Mar; 2024 Dec 19. PMID: 39706698.
- Colorectal surgeon practice patterns of low anterior resection syndrome after rectal cancer treatment.Coppersmith NA, Schultz KS, Esposito AC, Cruickshank K, Saleh A, Linhares SM, Leeds IL, Pantel HJ, Reddy VB, Longo WE, Mongiu AK. Support Care Cancer. 2025 Feb 24; 2025 Feb 24. PMID: 39994079.
- Hierarchical Multi-Label Classification With Gene-Environment Interactions in Disease Modeling.Li J, Zhang Q, Ma S, Fang K, Xu Y. Stat Med. 2025 Feb 10. PMID: 39865593.
- Bayesian Modeling of Cancer Outcomes Using Genetic Variables Assisted by Pathological Imaging Data.Im Y, Li R, Ma S. Stat Med. 2025 Feb 10. PMID: 39840672.
- Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) from contaminated water and risk of childhood cancer in California, 2000-2015.Binczewski NR, Morimoto LM, Wiemels JL, Ma X, Metayer C, Vieira VM. Environ Epidemiol. 2025 Feb; 2025 Jan 9. PMID: 39802752.
- Estimation of Cancer Deaths Averted From Prevention, Screening, and Treatment Efforts, 1975-2020.Goddard KAB, Feuer EJ, Mandelblatt JS, Meza R, Holford TR, Jeon J, Lansdorp-Vogelaar I, Gulati R, Stout NK, Howlader N, Knudsen AB, Miller D, Caswell-Jin JL, Schechter CB, Etzioni R, Trentham-Dietz A, Kurian AW, Plevritis SK, Hampton JM, Stein S, Sun LP, Umar A, Castle PE. JAMA Oncol. 2025 Feb 1. PMID: 39636625.
- The Incidence and Significance of Iliac Vein Stenosis in Patients with Deep Vein Thrombosis.Ali S, Chan SM, Brahmandam A, Xu Y, Deng Y, Elbadawy A, Lee A, Ochoa Chaar CI. Ann Vasc Surg. 2025 Feb; 2024 Nov 29. PMID: 39617297.
- Disparities in Colorectal Cancer Screening Before and After the Onset of the COVID Pandemic.Siddique S, Wang R, Gaddy JJ, Stempel JM, Warren JL, Gross CP, Ma X. J Gen Intern Med. 2025 Feb; 2024 Nov 4. PMID: 39495455.
- Telomere transcripts act as tumor suppressor and are associated with favorable prognosis in colorectal cancer with low proliferating cell nuclear antigen expression.Kienzl P, Deloria AJ, Hunjadi M, Hadolt JM, Haering MF, Bothien A, Mejri D, Korkut-Demirbaş M, Sampl S, Weber G, Pirker C, Laengle S, Braunschmid T, Dragona E, Marian B, Gagos S, Lu L, Henson JD, Lau LMS, Reddel RR, Mikulits W, Stättner S, Holzmann K. Cell Oncol (Dordr). 2025 Feb; 2024 Sep 2. PMID: 39222177.
- Treatment Access among Younger Medicaid Beneficiaries with Multiple Myeloma.Fiala MA, Ji M, Shih YH, Huber J, Wang M, Johnson KJ, Gasoyan H, Wang R, Colditz GA, Wang SY, Chang SH. Clin Lymphoma Myeloma Leuk. 2025 Feb; 2024 Aug 2. PMID: 39209567.
- Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway.Dudkina N, Park HB, Song D, Jain A, Khan SA, Flavell RA, Johnson CH, Palm NW, Crawford JM. Cell Chem Biol. 2025 Jan 16; 2024 Aug 19. PMID: 39163853.
- The Influence of DNA Repair Genes and Prenatal Tobacco Exposure on Risk of Childhood Acute Lymphoblastic Leukemia: A Gene-Environment Interaction Study.Wang X, Zhong C, Ma X, Metayer C, Mancuso N, Gauderman WJ, Wiemels JL. Cancer Epidemiol Biomarkers Prev. 2025 Jan 9. PMID: 39495115.
- OncoSexome: the landscape of sex-based differences in oncologic diseases.Shen X, Zhang Y, Li J, Zhou Y, Butensky SD, Zhang Y, Cai Z, DeWan AT, Khan SA, Yan H, Johnson CH, Zhu F. Nucleic Acids Res. 2025 Jan 6. PMID: 39535034.
- Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions.Jia G, Chen Z, Ping J, Cai Q, Tao R, Li C, Bauer JA, Xie Y, Ambs S, Barnard ME, Chen Y, Choi JY, Gao YT, Garcia-Closas M, Gu J, Hu JJ, Iwasaki M, John EM, Kweon SS, Li CI, Matsuda K, Matsuo K, Nathanson KL, Nemesure B, Olopade OI, Pal T, Park SK, Park B, Press MF, Sanderson M, Sandler DP, Shen CY, Troester MA, Yao S, Zheng Y, Ahearn T, Brewster AM, Falusi A, Hennis AJM, Ito H, Kubo M, Lee ES, Makumbi T, Ndom P, Noh DY, O'Brien KM, Ojengbede O, Olshan AF, Park MH, Reid S, Yamaji T, Zirpoli G, Butler EN, Huang M, Low SK, Obafunwa J, Weinberg CR, Zhang H, Zhao H, Cote ML, Ambrosone CB, Huo D, Li B, Kang D, Palmer JR, Shu XO, Haiman CA, Guo X, Long J, Zheng W. Nat Genet. 2025 Jan; 2025 Jan 3. PMID: 39753771.
- [Retracted] MicroRNA‑34a expression affects breast cancer invasion in vitro and patient survival via downregulation of E2F1 and E2F3 expression.Han R, Zhao J, Lu L. Oncol Rep. 2025 Jan; 2024 Nov 14. PMID: 39540400.
- Tertiary Lymphoid Structures and Immunotherapy: Challenges and Opportunities.Ruddle NH. Methods Mol Biol. 2025. PMID: 39527229.
- Living Flat: Stories from Women of Color After Mastectomy.Khubchandani JA, Suttiratana SC, Washington R, White-Bracey D, Kc M, Silber A, Fayanju OM, Butler PD, Menon A, Greenup RA. Ann Surg Oncol. 2025 Jan; 2024 Oct 15. PMID: 39407064.
- Strength of evidence underlying the CMS-FDA parallel review of comprehensive genomic profiling tests in the cancer setting.Stackland S, Schnabel D, Dinan MA, Presley CJ, Gross CP. J Natl Cancer Inst. 2025 Jan 1. PMID: 39288939.
- Understanding risk factors for endometrial cancer in young women.Peeri NC, Bertrand KA, Na R, De Vivo I, Setiawan VW, Seshan VE, Alemany L, Chen Y, Clarke MA, Clendenen T, Cook LS, Costas L, Dal Maso L, Freudenheim JL, Friedenreich CM, Gierach GL, Goodman MT, La Vecchia C, Levi F, Lopez-Querol M, Lu L, Moysich KB, Mutter G, Naduparambil J, Negri E, O'Connell K, O'Mara T, Palmer JR, Parazzini F, Penney KL, Petruzella S, Reynolds P, Ricceri F, Risch H, Rohan TE, Sacerdote C, Sandin S, Shu XO, Stolzenberg-Solomon RZ, Webb PM, Wentzensen N, Wilkens LR, Xu W, Yu H, Zeleniuch-Jacquotte A, Zheng W, Guo X, Lipworth L, Du M. J Natl Cancer Inst. 2025 Jan 1. PMID: 39235934.
- Artificial Intelligence-Enhanced Risk Stratification of Cancer Therapeutics-Related Cardiac Dysfunction Using Electrocardiographic Images.Oikonomou EK, Sangha V, Dhingra LS, Aminorroaya A, Coppi A, Krumholz HM, Baldassarre LA, Khera R. Circ Cardiovasc Qual Outcomes. 2025 Jan; 2024 Sep 2. PMID: 39221857.
- Varying the intensity of cystoscopic surveillance for high-risk non-muscle-invasive bladder cancer.Su ZT, Florissi IS, Mahon KM, Li T, Rezaee ME, Singla N, Patel SH, Townsend JP, Kates MR. BJU Int. 2025 Jan; 2024 Aug 29. PMID: 39210627.
- Exercise and Nutrition to Improve Cancer Treatment-Related Outcomes (ENICTO).Schmitz KH, Brown JC, Irwin ML, Robien K, Scott JM, Berger NA, Caan B, Cercek A, Crane TE, Evans SR, Ligibel JA, Meyerhardt JA, Agurs-Collins T, Basen-Engquist K, Bea JW, Cai SF, Cartmel B, Chinchilli VM, Demark-Wahnefried W, Dieli-Conwright CM, DiPietro L, Doerksen SE, Edelstein SL, Elena J, Evans W, Ferrucci LM, Foldi J, Freylersythe S, Furberg H, Jones LW, Levine R, Moskowitz CS, Owusu C, Penedo F, Rabin BA, Ratner E, Rosenzweig M, Salz T, Sanft T, Schlumbrecht M, Spielmann G, Thomson CA, Tjaden AH, Weiser MR, Yang S, Yu AF, Perna FM. J Natl Cancer Inst. 2025 Jan 1. PMID: 39118255.
- Asparagine synthetase and G-protein coupled estrogen receptor are critical responders to nutrient supply in KRAS mutant colorectal cancer.Lu L, Zhang Q, Aladelokun O, Berardi D, Shen X, Marin A, Garcia-Milian R, Roper J, Khan SA, Johnson CH. Int J Cancer. 2025 Jan 1; 2024 Jul 22. PMID: 39039782.
- Prostate-specific antigen screening for prostate cancer: Diagnostic performance, clinical thresholds, and strategies for refinement.Sundaresan VM, Smani S, Rajwa P, Renzulli J, Sprenkle PC, Kim IY, Leapman MS. Urol Oncol. 2025 Jan; 2024 Jul 17. PMID: 39019723.
- Incorporating prior information in gene expression network-based cancer heterogeneity analysis.Li R, Xu S, Li Y, Tang Z, Feng D, Cai J, Ma S. Biostatistics. 2024 Dec 31. PMID: 39074174.
- Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020.Ajjawi I, Loeb S, Cooperberg MR, Catalona WJ, Gross CP, Ma X, Leapman MS. JAMA. 2024 Dec 17. PMID: 39565605.
- Socio-economic factors associated with cancer stigma among apparently healthy women in two selected municipalities Nepal.Paneru B, Karmacharya A, Makaju S, Kafle D, Poudel L, Mali S, Timsina P, Shrestha N, Timalsena D, Chaudhary K, Bhandari N, Rai P, Shakya S, Spiegelman D, Sheth SS, Stangl A, Eastment MC, Shrestha A. PLoS One. 2024; 2024 Dec 16. PMID: 39680514.
- US Tobacco 21 Policies and Potential Mortality Reductions by State.Tam J, Crippen A, Friedman A, Jeon J, Colston DC, Fleischer NL, Vander Woude CA, Boelter MA, Holford TR, Levy DT, Meza R. JAMA Health Forum. 2024 Dec 6; 2024 Dec 6. PMID: 39705045.
- 16S rRNA target sequencing of human tumors validates findings of Lachnoclostridium abundance in human melanomas that are heavily CD8+ T-cell infiltrated.Lu L, Johnson C, Khan S, Kluger H. Eur J Cancer. 2024 Dec; 2024 Oct 24. PMID: 39477777.
- Diagnostic experiences of Black and White patients with uterine cancer: A qualitative study.Britton MC, Izampuye E, Clark M, Ornstein RA, Nunez-Smith M, Wright JD, Xu X. Gynecol Oncol. 2024 Dec; 2024 Oct 2. PMID: 39362045.
- A gap analysis of UK biobank publications reveals SNPs associated with intrinsic subtypes of breast cancer.van den Driest L, Kelly P, Marshall A, Johnson CH, Lasky-Su J, Lannigan A, Rattray Z, Rattray NJW. Comput Struct Biotechnol J. 2024 Dec; 2024 May 10. PMID: 38817965.
- Per- and polyfluoroalkyl substances (PFAS) and cancer: Detection methodologies, epidemiological insights, potential carcinogenic mechanisms, and future perspectives.Zheng J, Liu S, Yang J, Zheng S, Sun B. Sci Total Environ. 2024 Nov 25; 2024 Sep 8. PMID: 39255941.
- The critical need for a robust research agenda on ultra-processed food consumption and cancer risk.Loftfield E, Moore SC, Mayne ST. PLoS Med. 2024 Nov; 2024 Nov 19. PMID: 39561210.
- Correction: Randomized trial of physical activity on quality of life and lung cancer biomarkers in patients with advanced stage lung cancer: a pilot study.Bade BC, Gan G, Li F, Lu L, Tanoue L, Silvestri GA, Irwin ML. BMC Cancer. 2024 Nov 15; 2024 Nov 15. PMID: 39548453.
- Baseline predictors associated with successful weight loss among breast cancer survivors in the Lifestyle, Exercise, and Nutrition (LEAN) study.Hoobler R, Puklin LS, Harrigan M, Cartmel B, Li FY, Sanft T, Ferrucci LM, Irwin ML, Playdon MC. J Cancer Surviv. 2024 Nov 11; 2024 Nov 11. PMID: 39528779.
- Real-world analysis of two ischaemic stroke and TIA systolic blood pressure goals on 12-month mortality and recurrent vascular events.Sico JJ, Hu X, Myers LJ, Levine D, Bravata DM, Arling GW. Stroke Vasc Neurol. 2024 Nov 5; 2024 Nov 5. PMID: 38191185.
- Risk Score for Hepatocellular Cancer in Adults Without Viral Hepatitis or Cirrhosis.Ilagan-Ying YC, Gordon KS, Tate JP, Lim JK, Torgersen J, Lo Re V 3rd, Justice AC, Taddei TH. JAMA Netw Open. 2024 Nov 4; 2024 Nov 4. PMID: 39504020.
- Accessing breast cancer care in a protracted conflict: Qualitative exploration of the perspectives of women with breast cancer in northwest Syria.Marzouk M, Hamze M, Debel J, Alshemali A, Alameen BA, Bakkour M, Galal B, Chagpar AB, Atassi B, Khoshnood K, Abbara A. Soc Sci Med. 2024 Nov; 2024 Sep 21. PMID: 39357306.
- Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine.Machavariani E, Dumchev K, Pykalo I, Filippovych M, Ivasiy R, Esserman D, Madden LM, Bromberg DJ, Haddad M, Morozova O, Ahmad B, Gómez DO, Farnum SO, Dvoriak S, Altice FL. Contemp Clin Trials. 2024 Nov; 2024 Sep 14. PMID: 39265780.
- Associations Between Prostate Magnetic Resonance Imaging, Genomic Testing, and Treatment for Localized Prostate Cancer.Sundaresan VM, Wang R, Long JB, Sprenkle PC, Seibert TM, Loeb S, Cooperberg MR, Catalona WJ, Ma X, Gross CP, Leapman MS. Urol Pract. 2024 Nov; 2024 Jul 16. PMID: 39196719.
- Predictors of early life residential mobility in urban and rural Pennsylvania children with acute lymphoblastic leukemia and implications for environmental exposure assessment.Clark CJ, Warren JL, Saiers JE, Ma X, Bell ML, Deziel NC. J Expo Sci Environ Epidemiol. 2024 Nov; 2023 Dec 26. PMID: 38148338.
- Using a Bayesian analytic approach to identify county-level ecological factors associated with survival among individuals with early-onset colorectal cancer.Siddique S, Baum LVM, Deziel NC, Kelly JR, Warren JL, Ma X. PLoS One. 2024; 2024 Oct 29. PMID: 39471191.
- Updated CP*Trends: An Online Tool to Compare Cohort and Period Trends across Cancer Sites.Holford TR, Chen HS, Kane MJ, Krapcho M, Annett D, Esclamado L, Melkonyan A, Feuer EJ. Am J Epidemiol. 2024 Oct 28; 2024 Oct 28. PMID: 39475089.
- The protective effect of dietary folate intake on gastric cancer is modified by alcohol consumption: A pooled analysis of the StoP Consortium.Gonzalez-Palacios S, Compañ-Gabucio LM, Torres-Collado L, Oncina-Canovas A, García-de-la-Hera M, Collatuzzo G, Negri E, Pelucchi C, Rota M, López-Carrillo L, Lunet N, Morais S, Ward MH, Martin V, Lozano-Lorca M, Malekzadeh R, Pakseresht M, Hernández-Ramírez RU, Bonzi R, Patel L, López-Cervantes M, Rabkin CS, Tsugane S, Hidaka A, Trichopoulou A, Karakatsani A, Camargo MC, Curado MP, Zhang ZF, La Vecchia C, Boffetta P, Vioque J. Int J Cancer. 2024 Oct 15; 2024 May 16. PMID: 38757245.
- Catabolism of extracellular glutathione supplies amino acids to support tumor growth.Hecht F, Zocchi M, Tuttle ET, Ward NP, Smith B, Kang YP, Cazarin J, Soares ZG, Ozgurses ME, Zhao H, Sheehan C, Alimohammadi F, Munger LD, Trivedi D, Asantewaa G, Blick-Nitko SK, Zoeller JJ, Chen Y, Vasiliou V, Turner BM, Muir A, Coloff JL, Munger J, DeNicola GM, Harris IS. bioRxiv. 2024 Oct 13; 2024 Oct 13. PMID: 39416022.
- Thyroid Cancer Incidence During 2020 to 2021 COVID-19 Variant Waves.Bell R, Weinberger DM, Venkatesh M, Fernandes-Taylor S, Francis DO, Davies L. JAMA Otolaryngol Head Neck Surg. 2024 Oct 10; 2024 Oct 10. PMID: 39388144.
- Long-Term Outcomes of Prostate-Specific Membrane Antigen-PET Imaging of Recurrent Prostate Cancer.Kunst N, Long JB, Westvold S, Sprenkle PC, Kim IY, Saperstein L, Rabil M, Ghaffar U, Karnes RJ, Ma X, Gross CP, Wang SY, Leapman MS. JAMA Netw Open. 2024 Oct 1; 2024 Oct 1. PMID: 39441595.
- Clinician Staffing and Quality of Care in US Health Centers.Sun QW, Forman HP, Stern L, Oldfield BJ. JAMA Netw Open. 2024 Oct 1; 2024 Oct 1. PMID: 39436649.
- USPSTF Colorectal Cancer Screening Recommendation and Uptake for Individuals Aged 45 to 49 Years.Siddique S, Wang R, Yasin F, Gaddy JJ, Zhang L, Gross CP, Ma X. JAMA Netw Open. 2024 Oct 1; 2024 Oct 1. PMID: 39361285.
- Patterns of Physical Therapy Referral and Subsequent Attendance Among Childhood Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy at a Regional Childhood Cancer Survivorship Clinic.Kang L, Kadan-Lottick NS, Rotatori J, Kujawski SE, Messerschmidt E, Auerbach C, Balsamo LM, Lustberg MB, Ma X, Rodwin RL. Semin Oncol Nurs. 2024 Oct; 2024 Aug 19. PMID: 39164160.
- Characterization of time toxicity in older patients with metastatic breast cancer.Atre SY, Soulos PR, Kuderer NM, Gross CP, Baum LVM, Dinan MA, Lustberg MB. Breast Cancer Res Treat. 2024 Oct; 2024 May 31. PMID: 38816556.
- Charting the metabolic biogeography of the colorectum in cancer: challenging the right sided versus left sided classification.Jain A, Morris MT, Berardi D, Arora T, Domingo-Almenara X, Paty PB, Rattray NJW, Kerekes D, Lu L, Khan SA, Johnson CH. Mol Cancer. 2024 Sep 28; 2024 Sep 28. PMID: 39342363.
- The impact of chiropractic care on prescription opioid use for non-cancer spine pain: protocol for a systematic review and meta-analysis.Emary PC, Corcoran KL, Coleman BC, Brown AL, Ciraco C, DiDonato J, Wang L, Couban RJ, Sud A, Busse JW. Syst Rev. 2024 Sep 12; 2024 Sep 12. PMID: 39267131.
- Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery.Liu M, Jin S, Agabiti SS, Jensen TB, Yang T, Radda JSD, Ruiz CF, Baldissera G, Rajaei M, Townsend JP, Muzumdar MD, Wang S. bioRxiv. 2024 Sep 9; 2024 Sep 9. PMID: 37546882.
Centers and other resources
- Yale Cancer Center (YCC)The Center provides the best approaches for the prevention, detection, diagnosis, and treatment of cancer.
- Yale Center for Analytical Sciences (YCAS)YCAS collaborative team provides expertise in the design, conduct, and analysis of health and health care studies, methodological development, and education and training.
- Yale-Griffin Prevention Research Center (PRC)The PRC works with community partners to develop and implement community-based approaches to prevent and control chronic diseases such as heart disease, diabetes, and cancer.