- July 19, 2024Source: Medical News Today
Physical exercise may help prevent nerve damage during chemotherapy, study finds
- July 03, 2024
Ambient heat during pregnancy linked to increased risk of childhood cancer
- June 13, 2024Source: The Guardian
Rare cancers, full-body rashes, death: did fracking make their kids sick?
- May 28, 2024
Dr. Vasilis Vasiliou on Yale Cancer Answers
Cancer
More people today die from cancer than from almost any other cause in the world. The challenges posed by cancer are immense and top scientists at the Yale School of Public Health are committed to reducing its toll.
The departments of Chronic Disease Epidemiology, Biostatistics and Health Policy and Management are heavily focused on a wide variety of cancer-related research, and the Department of Environmental Health Sciences is renowned for novel approaches to the study of how environmental exposures affect health outcomes. From key partnerships with the Yale Cancer Center to collaborative efforts locally and globally, YSPH scientists are taking significant steps toward preventing and treating a wide range of cancers. Today, research in cancer and other chronic diseases encompasses interdisciplinary teams committed to understanding cancer causation and etiology, prevention, screening and early detection, risk factors, environmental exposures, social determinants of health and survival.
A variety of technologies and approaches are used to detect mechanisms and characteristics of the many different types of cancer, including genomics, metabolomics, social and behavioral effects, evolutionary biology, biostatistical methodology and study design, and outcomes research.
The Yale School of Public Health maintains biospecimens and data from thousands of individuals in more than a dozen studies that can be made applied to future research. It also has partnerships with numerous international cancer researchers, and is the home of leading experts in clinical trial design and data management, and genomic and metabolic centers.
Recent Publications
2024
- A gap analysis of UK biobank publications reveals SNPs associated with intrinsic subtypes of breast cancer.van den Driest L, Kelly P, Marshall A, Johnson CH, Lasky-Su J, Lannigan A, Rattray Z, Rattray NJW. Comput Struct Biotechnol J. 2024 Dec; 2024 May 10. PMID: 38817965.
- The protective effect of dietary folate intake on gastric cancer is modified by alcohol consumption: A pooled analysis of the StoP Consortium.Gonzalez-Palacios S, Compañ-Gabucio LM, Torres-Collado L, Oncina-Canovas A, García-de-la-Hera M, Collatuzzo G, Negri E, Pelucchi C, Rota M, López-Carrillo L, Lunet N, Morais S, Ward MH, Martin V, Lozano-Lorca M, Malekzadeh R, Pakseresht M, Hernández-Ramírez RU, Bonzi R, Patel L, López-Cervantes M, Rabkin CS, Tsugane S, Hidaka A, Trichopoulou A, Karakatsani A, Camargo MC, Curado MP, Zhang ZF, La Vecchia C, Boffetta P, Vioque J. Int J Cancer. 2024 Oct 15; 2024 May 16. PMID: 38757245.
- Patterns of Physical Therapy Referral and Subsequent Attendance Among Childhood Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy at a Regional Childhood Cancer Survivorship Clinic.Kang L, Kadan-Lottick NS, Rotatori J, Kujawski SE, Messerschmidt E, Auerbach C, Balsamo LM, Lustberg MB, Ma X, Rodwin RL. Semin Oncol Nurs. 2024 Oct; 2024 Aug 19. PMID: 39164160.
- Strength of Evidence Underlying the CMS-FDA Parallel Review of Comprehensive Genomic Profiling Tests in the Cancer Setting.Stackland S, Schnabel D, Dinan M, Presley CJ, Gross CP. J Natl Cancer Inst. 2024 Sep 18; 2024 Sep 18. PMID: 39288939.
- Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine.Machiavariani E, Dumchev K, Pykalo I, Filippovych M, Ivasiy R, Esserman D, Madden LM, Bromberg DJ, Haddad M, Morozova O, Ahmad B, Gómez DO, Farnum SO, Dvoriak S, Altice FL. Contemp Clin Trials. 2024 Sep 14; 2024 Sep 14. PMID: 39265780.
- The impact of chiropractic care on prescription opioid use for non-cancer spine pain: protocol for a systematic review and meta-analysis.Emary PC, Corcoran KL, Coleman BC, Brown AL, Ciraco C, DiDonato J, Wang L, Couban RJ, Sud A, Busse JW. Syst Rev. 2024 Sep 12; 2024 Sep 12. PMID: 39267131.
- Per- and polyfluoroalkyl substances (PFAS) and cancer: Detection methodologies, epidemiological insights, potential carcinogenic mechanisms, and future perspectives.Zheng J, Liu S, Yang J, Zheng S, Sun B. Sci Total Environ. 2024 Sep 8; 2024 Sep 8. PMID: 39255941.
- Understanding risk factors for endometrial cancer in young women.Peeri NC, Bertrand KA, Na R, De Vivo I, Setiawan VW, Seshan VE, Alemany L, Chen Y, Clarke MA, Clendenen T, Cook LS, Costas L, Dal Maso L, Freudenheim JL, Friedenreich CM, Gierach GL, Goodman MT, La Vecchia C, Levi F, Lopez-Querol M, Lu L, Moysich KB, Mutter G, Naduparambil J, Negri E, O'Connell K, O'Mara T, Palmer JR, Parazzini F, Penney KL, Petruzella S, Reynolds P, Ricceri F, Risch H, Rohan TE, Sacerdote C, Sandin S, Shu XO, Stolzenberg-Solomon RZ, Webb PM, Wentzensen N, Wilkens LR, Xu W, Yu H, Zeleniuch-Jacquotte A, Zheng W, Guo X, Lipworth L, Du M. J Natl Cancer Inst. 2024 Sep 5; 2024 Sep 5. PMID: 39235934.
- Folate Metabolism and Risk of Childhood Acute Lymphoblastic Leukemia: A Genetic Pathway Analysis from the Childhood Cancer and Leukemia International Consortium.Metayer C, Spector LG, Scheurer ME, Jeon S, Scott RJ, Takagi M, Clavel J, Manabe A, Ma X, Hailu EM, Lupo PJ, Urayama KY, Bonaventure A, Kato M, Meirhaeghe A, Chiang CWK, Morimoto LM, Wiemels JL. Cancer Epidemiol Biomarkers Prev. 2024 Sep 3. PMID: 38904462.
- Genome-Wide Analysis to Assess if Heavy Alcohol Consumption Modifies the Association between SNPs and Pancreatic Cancer Risk.Ni Z, Kundu P, McKean DF, Wheeler W, Albanes D, Andreotti G, Antwi SO, Arslan AA, Bamlet WR, Beane-Freeman LE, Berndt SI, Bracci PM, Brennan P, Buring JE, Chanock SJ, Gallinger S, Gaziano JM, Giles GG, Giovannucci EL, Goggins MG, Goodman PJ, Haiman CA, Hassan MM, Holly EA, Hung RJ, Katzke V, Kooperberg C, Kraft P, LeMarchand L, Li D, McCullough ML, Milne RL, Moore SC, Neale RE, Oberg AL, Patel AV, Peters U, Rabe KG, Risch HA, Shu XO, Smith-Byrne K, Visvanathan K, Wactawski-Wende J, White E, Wolpin BM, Yu H, Zeleniuch-Jacquotte A, Zheng W, Zhong J, Amundadottir LT, Stolzenberg-Solomon RZ, Klein AP. Cancer Epidemiol Biomarkers Prev. 2024 Sep 3. PMID: 38869494.
- Telomere transcripts act as tumor suppressor and are associated with favorable prognosis in colorectal cancer with low proliferating cell nuclear antigen expression.Kienzl P, Deloria AJ, Hunjadi M, Hadolt JM, Haering MF, Bothien A, Mejri D, Korkut-Demirbaş M, Sampl S, Weber G, Pirker C, Laengle S, Braunschmid T, Dragona E, Marian B, Gagos S, Lu L, Henson JD, Lau LMS, Reddel RR, Mikulits W, Stättner S, Holzmann K. Cell Oncol (Dordr). 2024 Sep 2; 2024 Sep 2. PMID: 39222177.
- Artificial Intelligence-Enhanced Risk Stratification of Cancer Therapeutics-Related Cardiac Dysfunction Using Electrocardiographic Images.Oikonomou EK, Sangha V, Dhingra LS, Aminorroaya A, Coppi A, Krumholz HM, Baldassarre LA, Khera R. Circ Cardiovasc Qual Outcomes. 2024 Sep 2; 2024 Sep 2. PMID: 39221857.
- A Brief Report of Lung Cancer Screening Utilization Before, During, and in the Later Stages of the COVID-19 Pandemic in the United States.Poghosyan H, Sarkar S, Richman I, Pietrzak RH, Carter-Bawa L, Cooley ME. JTO Clin Res Rep. 2024 Sep; 2024 Jul 6. PMID: 39282662.
- Genomic Landscape of Osteosarcoma of Bone in an Older-Aged Patient Population and Analysis of Possible Etiologies Based on Molecular Signature.Kaseb H, Tan C, Townsend JP, Costa J, Laskin WB. Genet Test Mol Biomarkers. 2024 Sep; 2024 Jul 25. PMID: 39052504.
- Alternative Payment Models and Performance in Federally Qualified Health Centers.Markowski J, Wallace J, Schlesinger M, Ndumele CD. JAMA Intern Med. 2024 Sep 1. PMID: 38976258.
- Medical Marijuana for Pain Management in Hospice Care as a Complementary Approach to Scheduled Opioids: A Single Arm Study.Zanker T, Sacco J, Prota J, Palma M, Viola Lee KA, Wang RR, Liang Y, Cunningham J, Mackary M, Ovchinnikova P. Am J Hosp Palliat Care. 2024 Sep; 2023 Dec 15. PMID: 38100655.
- Varying the intensity of cystoscopic surveillance for high-risk non-muscle-invasive bladder cancer.Su ZT, Florissi IS, Mahon KM, Li T, Rezaee ME, Singla N, Patel SH, Townsend JP, Kates MR. BJU Int. 2024 Aug 29; 2024 Aug 29. PMID: 39210627.
- Expression and clinicopathologic significance of HER2 and PD-L1 in high grade urothelial carcinoma of the urinary tract.Li P, Ni P, Haines GK, Si Q, Li X, Baskovich B. Int J Clin Exp Pathol. 2024; 2024 Aug 15. PMID: 39262437.
- Barriers to and facilitators of improving physical activity and nutrition behaviors during chemotherapy for breast cancer: a sequential mixed methods study.Puklin LS, Irwin ML, Sanft T, Ferrucci LM, Harrigan M, McGowan C, Cartmel B, Zupa M, Winer EP, Deyling M, Ligibel JA, Basen-Engquist K, Spiegelman D, Sharifi M. Support Care Cancer. 2024 Aug 14; 2024 Aug 14. PMID: 39141176.
- National age-specific mortality trends for cervical and breast cancers in urban-rural areas of China from 2009 to 2021: a population-based analysis.Li ML, Qi JL, Ma YQ, Shu W, Xiao HD, Wang LJ, Yin P, Guo HY, Vermund SH, Zhou MG, Hu YF. Mil Med Res. 2024 Aug 13; 2024 Aug 13. PMID: 39138529.
- Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway.Dudkina N, Park HB, Song D, Jain A, Khan SA, Flavell RA, Johnson CH, Palm NW, Crawford JM. Cell Chem Biol. 2024 Aug 9; 2024 Aug 9. PMID: 39163853.
- Exercise and nutrition to improve cancer Treatment-Related outcomes (ENICTO).Schmitz KH, Brown JC, Irwin ML, Robien K, Scott JM, Berger NA, Caan B, Cercek A, Crane TE, Evans SR, Ligibel JA, Meyerhardt JA, Agurs-Collins T, Basen-Engquist K, Bea JW, Cai SF, Cartmel B, Chinchilli VM, Demark-Wahnefried W, Dieli-Conwright CM, DiPietro L, Doerksen SE, Edelstein SL, Elena J, Evans W, Ferrucci LM, Foldi J, Freylersythe S, Furberg H, Jones LW, Levine R, Moskowitz CS, Owusu C, Penedo F, Rabin BA, Ratner E, Rosenzweig M, Salz T, Sanft T, Schlumbrecht M, Spielmann G, Thomson CA, Tjaden AH, Weiser MR, Yang S, Yu AF, Perna FM. J Natl Cancer Inst. 2024 Aug 8; 2024 Aug 8. PMID: 39118255.
- Association Between the Decipher Genomic Classifier and Prostate Cancer Outcome in the Real-world Setting.Leapman MS, Ho J, Liu Y, Filson C, Zhao X, Hakansson A, Proudfoot JA, Davicioni E, Martin DT, An Y, Seibert TM, Lin DW, Spratt DE, Cooperberg MR, Sprenkle PC, Ross AE. Eur Urol Oncol. 2024 Aug 3; 2024 Aug 3. PMID: 39098389.
- Treatment Access among Younger Medicaid Beneficiaries with Multiple Myeloma.Fiala MA, Ji M, Shih YH, Huber J, Wang M, Johnson KJ, Gasoyan H, Wang R, Colditz GA, Wang SY, Chang SH. Clin Lymphoma Myeloma Leuk. 2024 Aug 2; 2024 Aug 2. PMID: 39209567.
- Smoking patterns by birth cohort in Argentina: an age-period-cohort population-based modeling study.Salgado MV, Mok Y, Jeon J, Jaffri M, Tam J, Holford TR, Sánchez-Romero LM, Meza R, Mejia R. Lancet Reg Health Am. 2024 Aug; 2024 Jun 21. PMID: 39006127.
Click here to download the full summary of YSPH 2023 research findings in publication.
for Faculty working in this area.
The Yale Cancer Prevention and Control Training Program
Centers and other resources
- Yale Cancer Center (YCC)The Center provides the best approaches for the prevention, detection, diagnosis, and treatment of cancer.
- Yale Center for Analytical Sciences (YCAS)YCAS collaborative team provides expertise in the design, conduct, and analysis of health and health care studies, methodological development, and education and training.
- Yale-Griffin Prevention Research Center (PRC)The PRC works with community partners to develop and implement community-based approaches to prevent and control chronic diseases such as heart disease, diabetes, and cancer.