- September 19, 2023
Colon Tumor Location Matters for Metastatic Disease, According to Study
- September 13, 2023
Metabolomic Research Links Diet to Paraben Food Preservatives in Urine, Findings Important for Women Trying to Conceive
- August 28, 2023
Chemical compounds in extra virgin olive oil could aid in the treatment and prevention of Alzheimer’s disease
- August 28, 2023
AI-Powered Triage Platform Could Aid Future Viral Outbreak Response
Lifestyle Factors
As many emerging economies around the world adopt Westernized diets and lifestyles, noncommunicable diseases are rising at alarming rates across the globe.
Lifestyle factors such as use of tobacco and alcohol, diet and physical activity are closely associated with myriad chronic health conditions such as cancer, diabetes, obesity and cardiovascular disease. Scientists have found, for example, that unhealthy body weight, limited physical activity and poor diets are associated with an increased incidence of 13 cancers, and an increased mortality of 14 cancers in addition to metabolic diseases.
By altering hormones, lifestyle factors also can affect energy metabolism, cellular growth, steroid metabolism, inflammatory mediation, DNA repair and immune function. In addition, malnutrition increases morbidity and mortality from infectious diseases, and can increase the severity of an infection and hinder the response to treatment.
To address these conditions, Yale School of Public Health researchers are using rigorous interdisciplinary and epidemiologic methods to understand the health consequences of nutrition, exercise, genetics, biomarkers, access to health services, community-based characteristics on disease rates and outcomes, epigenetics of obesity, lifestyle interventions in oncology care, breastfeeding and the impact of climate change, among other factors.
Recent Publications
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Nicotine & Tobacco Research
The Impact of Smoke-free Air Laws and Conventional Cigarette Taxes on Cardiovascular Hospitalizations
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American Journal of Epidemiology
Associations Between Asthma and Body Mass Index -
American Journal of Human Biology
Changing Body Norms: Samoa in 1995 and 2018 -
Nutrition Research
Skin Carotenoids are Inversely Associated with Adiposity in Breast Cancer Survivors
Centers and other resources
YSPH Gene-Lifestyle-Environmental Interactions 2022 Research Highlights
- Obesity (Silver Spring)The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans
- The American Journal of Human GeneticsLeveraging LD eigenvalue regression to improve the estimation of SNP heritability and confounding inflation