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Stephanie Perniciaro, PhD, MPH

Associate Research Scientist in Epidemiology (Microbial Diseases)

Contact Information

Stephanie Perniciaro, PhD, MPH

Mailing Address

  • Epidemiology of Microbial Diseases

    350 George Street

    New Haven, CT 06515

    United States

Research Summary

There are numerous vaccines designed to prevent acute respiratory disease, including those targeted to influenza, COVID-19, RSV, Streptococcus pneumoniae, Bordatella pertussis, Corynebacterim diphtheriae, and Haemophilus influenzae. I study vaccine effectiveness and vaccine impact, describing when, where, and how well the vaccines are preventing disease and death in various populations. I'm interested in respiratory disease surveillance, pneumococcal serotype replacement and serotype distribution, vaccine scheduling policy and recommendations, and optimizing vaccine use to protect the full population.

Extensive Research Description

I worked in a sewage treatment facility, analyzing wastewater, sludge, and solids in the laboratory and catching fish and aqueous invertebrates on the bioinventory team. I worked in a VA hospital laboratory, performing endocrine experiments on obese rats. I assisted on a study of thermoregulatory behavior of lizards in the Sonoran Desert. I worked in a nutritional epidemiology laboratory, processing blood and urine samples. I worked in intraoperative research, testing medical devices and collecting various secretions. I worked in the German National Reference Center for Streptococci, registering and analyzing high volumes of bacterial isolates, then designing and carrying out various epidemiological studies related to the surveillance and sample collection.

The overarching goal of my research now is to optimize vaccine impact for respiratory disease, which requires unity between surveillance, policy, and advocacy. I want to determine how we should select vaccines for particular populations and how we should design future vaccines. I want to establish the best way to structure vaccine schedules, which segments of the population should receive vaccines, and how to improve vaccine uptake. I investigate the current and potential effects of using vaccines. In order to unravel these questions, high-quality, long-term, stable disease surveillance systems are essential.


Research Interests

Child; Data Collection; Disease Outbreaks; Immunization; Infant; Influenza, Human; Pneumonia; Population Surveillance; Public Health; Refugees; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; Streptococcus pyogenes; Epidemiologic Studies; Bacteremia; Gram-Positive Bacterial Infections; Community-Acquired Infections; Molecular Epidemiology; Pneumonia, Bacterial; Disease Transmission, Infectious; Disease Notification; Sentinel Surveillance; Endemic Diseases; Communicable Diseases, Emerging; Vulnerable Populations; Emigrants and Immigrants; Genome-Wide Association Study; Coinfection; Public Health Systems Research; Vaccine-Preventable Diseases

Public Health Interests

Antimicrobial Resistance; Emerging Infectious Diseases; Global Health; Health Care Quality, Efficiency; Health Policy; Modeling; Respiratory Disease/Infections; Vaccines; Health Systems Reform

Selected Publications