About
Titles
Professor Adjunct
Biography
Xiaoming Shi is the Professor and Director of the National Institute of Environmental Health (NIEH), Chinese Center for Disease Control and Prevention (China CDC). Professor Shi received his MD in 1999 from Anhui Medical University and PhD in Epidemiology and Health Statistics in 2005 from the China CDC. He joined the branch of Infectious Disease Surveillance, China CDC in 2005, and then worked as the head of the Branch of Monitoring and Evaluation, Division of non-communicable Disease (NCDs) Control and Community Health, China CDC. In 2015, he was appointed as the Director of NIEH, China CDC.
Dr. Shi has received a number of grants from the Ministry of Science and Technology of China, National Natural Science Foundation of China (NSFC), as well as international agencies and organizations (e.g., United Nations Population Fund) to conduct research on healthy longevity and environmental health, and more. He has also contributed to the establishment the National Human Bio-monitoring (NHBM) of China to assess for the first time the internal exposure levels of environmental chemicals in the Chinese population. Dr. Shi is currently leading a large-scale project systematically assessing the acute health risks of air pollution in China. He and his research group conducted a cohort study on sub-clinical outcomes of polluted air in China (SCOPA-China Cohort) and a well-designed panel study on biomarkers of air pollutants exposure among Chinese aged 60-69 (China BAPE). He has published over 200 peer-reviewed journal articles and authored/co-authored in over 10 book chapters and books.
Appointments
Environmental Health Sciences
Professor AdjunctPrimary
Other Departments & Organizations
Research
Research at a Glance
Yale Co-Authors
Publications Timeline
Krystal Pollitt, PhD, P.Eng.
Pengfei Guo, MBBS, PhD
Publications
Associations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study
Zheng X, Pan Y, Qu Y, Ji S, Wang J, Li Z, Zhao F, Wu B, Xie L, Li Y, Song H, Hu X, Qiu Y, Zhang Z, Zhang W, Yang Y, Cai J, Zhu Y, Zhu Y, Cao Z, Ji J, Lv Y, Dai J, Shi X. Associations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study. Environmental Science And Technology 2024 PMID: 38980177, DOI: 10.1021/acs.est.3c11095.Peer-Reviewed Original ResearchConceptsNationwide cross-sectional studyPublic health planningCross-sectional studyOdds of hyperuricemiaChinese adultsHealth plansJoint effectsElevated oddsGeneral populationNationwide studyNonmonotonic dose responsePositive associationRisk factorsAdultsHealthEffects of polyfluoroalkyl substancesHealth hazardsParticipantsSerum polyfluoroalkyl substancesJoint effects of PFAS mixtureMeasured serum concentrationsFish consumptionSerum concentrations of uric acidAssociationHyperuricemiaAnalysis of changes in social isolation, loneliness, or both, and subsequent cognitive function among older adults: Findings from a nationwide cohort study
Huang Q, Zhang P, Shen D, Gao J, Li Z, Lv Y, Shi X, Mao C. Analysis of changes in social isolation, loneliness, or both, and subsequent cognitive function among older adults: Findings from a nationwide cohort study. Alzheimer's & Dementia 2024 PMID: 38946708, DOI: 10.1002/alz.14080.Peer-Reviewed Original ResearchConceptsAssociated with accelerated cognitive declineCognitive impairment riskPersistent lonelinessSocial isolationCognitive declineOlder adultsImpairment riskChinese Longitudinal Healthy Longevity SurveyIncident cognitive impairmentCognitive impairmentAssociation of changesNationwide cohort studyAccelerated cognitive declineCognitive functionLongevity SurveyCohort studyChanging statusLonelinessRisk factorsRegression modelsTobit regression modelCox modelShort-termRiskAdultsMetabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study
Song W, Zhong W, Gao J, Li Z, Ren J, Shen D, Wang X, Shen Q, You F, Fu Q, Li C, Chen H, Lv Y, Shi X, Mao C. Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study. International Journal Of Obesity 2024, 1-9. PMID: 38926462, DOI: 10.1038/s41366-024-01571-x.Peer-Reviewed Original ResearchConceptsMetabolically unhealthy non-obeseMetabolically healthy non-obeseMetabolically healthy obesityMetabolic obesity phenotypesOldest-old populationMetabolically unhealthy obesityProspective cohort studyMortality riskCohort studyHazard ratioObese phenotypeManagement of metabolic healthUnhealthy non-obeseOldest-old adultsHealthy non-obeseMethodsThis prospective cohort studyDecreased mortality riskIncreased mortality riskHigher mortality riskYears of follow-upAll-cause mortalityNon-obeseEffect of obesityHealthy obesityCentral obesityPersonal exposure to airborne organic pollutants and lung function changes among healthy older adults
Guo X, Ren H, Sun P, Ding E, Fang J, Fang K, Ma X, Li C, Li C, Xu Y, Cao K, Lin E, Guo P, Pollitt K, Tong S, Tang S, Shi X. Personal exposure to airborne organic pollutants and lung function changes among healthy older adults. Environmental Research 2024, 258: 119411. PMID: 38876423, DOI: 10.1016/j.envres.2024.119411.Peer-Reviewed Original Research[Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China].
Zhou J, Qi L, Wang J, Liu S, Shi W, Ye L, Zhang Z, Zhang Z, Meng X, Cui J, Chen C, Lyu Y, Shi X. [Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China]. Chinese Journal Of Epidemiology 2024, 45: 809-816. PMID: 38889980, DOI: 10.3760/cma.j.cn112338-20231205-00333.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsDaily living scoresPredictors of frailtyArea under the receiver operating characteristic curveIncident frailtyOlder adultsLiving scoresChinese Longitudinal Healthy Longevity SurveyRisk thresholdSelf-rated healthChinese older adultsRisk of incident frailtyRisk of frailtyFree of frailtyPhysical examination variablesCox proportional hazards regression modelsProportional hazards regression modelsRisk prediction modelInstrumental activitiesHazards regression modelsLongevity SurveyFrailty incidenceFollow-up timeDecision-curve analysisOlder personsReceiver operating characteristic curvePositive Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Hypertension May Be Attenuated by Endogenous Sex Hormones: A Nationally Representative Cross-Sectional Study
Wu B, Sheng N, Li Z, Wang J, Ji S, Zhao F, Pan Y, Qu Y, Wei Y, Xie L, Li Y, Hu X, Wu C, Zhang Z, Qiu Y, Zheng X, Zhang W, Hu X, Song H, Cai J, Cao Z, Ji J, Lv Y, Dai J, Shi X. Positive Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Hypertension May Be Attenuated by Endogenous Sex Hormones: A Nationally Representative Cross-Sectional Study. Hypertension 2024, 81: 1799-1810. PMID: 38853753, DOI: 10.1161/hypertensionaha.123.22127.Peer-Reviewed Original ResearchConceptsDiastolic blood pressureSystolic blood pressureEndogenous sex hormonesBlood pressureNationally representative cross-sectional studyPositive associationPerfluoroheptane sulfonic acidWeighted multiple logistic regressionSex hormonesLevels of endogenous sex hormonesPrevalence of hypertensionCross-sectional studyMultiple logistic regressionAssociations of polyfluoroalkyl substancesPFAS mixtureJoint effects of PFAS mixtureAssociated with hypertensionProgression of hypertensionChinese adultsSynergy indexOdds ratioG-computationQuantile-based g-computationRisk ratioLogistic regressionA Prospective Cohort Study of Antimony Exposure and Cognitive Impairment in Older Adults — China, 2017–2021
Qiu Y, Ji S, Chen C, Zhou J, Wang J, Wu B, Wei Y, Li F, Zheng X, Xu L, Zhang Z, Zhao F, Chen G, Ji J, Lyu Y, Tong S, Shi X. A Prospective Cohort Study of Antimony Exposure and Cognitive Impairment in Older Adults — China, 2017–2021. China CDC Weekly 2024, 6: 537-541. PMID: 38933661, PMCID: PMC11196874, DOI: 10.46234/ccdcw2024.104.Peer-Reviewed Original Research[Exploring implementation strategies for healthy longevity among the elderly population in China based on the delphi method].
Chai X, Cui J, Ye L, Lyu Y, Shao R, Zhang J, Shi X. [Exploring implementation strategies for healthy longevity among the elderly population in China based on the delphi method]. Chinese Preventive Medicine 2024, 58: 883-890. PMID: 38955737, DOI: 10.3760/cma.j.cn112150-20230804-00056.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsHarmony coefficientsImplementation strategiesHealthy longevityAuthority coefficientPromote healthy longevityExpert active coefficientElderly populationChinese elderly populationDelphi methodDelphi consultationConsultation questionnaireElderly care service industryPublic healthFeasibility scoreScore of feasibilityAverage scoreConsultationExpert discussionScoresLiterature reviewClinical medicineHealthy Lifestyle and the Likelihood of Becoming a Centenarian
Li Y, Wang K, Jigeer G, Jensen G, Tucker K, Lv Y, Shi X, Gao X. Healthy Lifestyle and the Likelihood of Becoming a Centenarian. JAMA Network Open 2024, 7: e2417931. PMID: 38900423, PMCID: PMC11190803, DOI: 10.1001/jamanetworkopen.2024.17931.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsHealthy lifestyleCase-control studyLifestyle factorsOlder adultsChinese Longitudinal Healthy Longevity SurveySelf-reported chronic conditionsHealthy lifestyle scoreImprove lifestyle behaviorsChinese older adultsAssociated with life expectancyProspective nested case-control studyNested case-control studyLifestyle scoreLifestyle behaviorsLongevity SurveyOlder age groupsHealth outcomesChronic conditionsSociodemographic characteristicsCommunity-basedMental wellnessYear of entryMain OutcomesOdds ratioMiddle-agedDietary seafood as a potential modifier in the relationship between per- and polyfluoroalkyl substances (PFASs) burden and prediabetes/diabetes: Insights from a nationally representative cross-sectional study
Qu Y, Sheng N, Ji S, Li Z, Wang J, Pan Y, Hu X, Zheng X, Li Y, Song H, Xie L, Zhang W, Cai J, Zhao F, Zhu Y, Cao Z, Lv Y, Dai J, Shi X. Dietary seafood as a potential modifier in the relationship between per- and polyfluoroalkyl substances (PFASs) burden and prediabetes/diabetes: Insights from a nationally representative cross-sectional study. Journal Of Hazardous Materials 2024, 473: 134645. PMID: 38762989, DOI: 10.1016/j.jhazmat.2024.134645.Peer-Reviewed Original ResearchConceptsPolyfluoroalkyl substancesSeafood consumptionImpact of polyfluoroalkyl substancesPFAS burdenPFAS levelsHuman biomonitoring dataEffects of PFAS exposureDietary seafoodSeafood consumersCl-PFESABiomonitoring dataSeafood intakePFAS concentrationsPolyfluoroalkyl substances exposuresSeafoodLevels of PERPFAS exposurePFOSPolyfluoroalkylNon-linear relationshipSerum PFAS concentrationsPERPrevalence of prediabetesPFOAPFUnDA