Ralitza Gueorguieva, PhD

• Eugenia Buta
• Heping Zhang
• Jody L. Sindelar
• Robert Makuch

Psychiatry; Research Design; Models, Statistical; Risk Assessment; Biostatistics

Epidemiology Methods; Maternal & Child Health; Mental Health; Modeling; Substance Use, Addiction

• Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial.Grilo C, Lydecker J, Gueorguieva R. Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2023, 1-10. PMID: 37366017, DOI: 10.1017/s0033291723001800.
• Gambling participation among Connecticut adolescents from 2007 to 2019: Potential risk and protective factors.Stefanovics E, Gueorguieva R, Zhai Z, Potenza M. Gambling participation among Connecticut adolescents from 2007 to 2019: Potential risk and protective factors. Journal Of Behavioral Addictions 2023 PMID: 37335777, DOI: 10.1556/2006.2023.00027.
• Sex steroid hormone levels associated with dopamine D2/3 receptor availability in people who smoke cigarettesZakiniaeiz Y, Gueorguieva R, Peltier M, Verplaetse T, Roberts W, McKee S, Cosgrove K. Sex steroid hormone levels associated with dopamine D2/3 receptor availability in people who smoke cigarettes Frontiers In Behavioral Neuroscience 2023, 17: 1192740. PMID: 37358969, PMCID: PMC10288103, DOI: 10.3389/fnbeh.2023.1192740.
• Does Symptom-Onset Treatment With a Sertraline Improve Functional Impairment for Individuals With Premenstrual Dysphoric Disorder?: A Randomized Controlled Trial.Yonkers K, Altemus M, Gilstad-Hayden K, Kornstein S, Gueorguieva R. Does Symptom-Onset Treatment With a Sertraline Improve Functional Impairment for Individuals With Premenstrual Dysphoric Disorder?: A Randomized Controlled Trial. Journal Of Clinical Psychopharmacology 2023, Publish Ahead of Print PMID: 37212651, DOI: 10.1097/jcp.0000000000001700.
• Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trialGrilo C, Lydecker J, Gueorguieva R. Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial International Journal Of Eating Disorders 2023 PMID: 37144325, DOI: 10.1002/eat.23975.
• Randomized controlled trial of the glycine transporter 1 inhibitor PF-03463275 to enhance cognitive training and neuroplasticity in schizophreniaSurti T, Ranganathan M, Johannesen J, Gueorguieva R, Deaso E, Kenney J, Krystal J, D'Souza D. Randomized controlled trial of the glycine transporter 1 inhibitor PF-03463275 to enhance cognitive training and neuroplasticity in schizophrenia Schizophrenia Research 2023, 256: 36-43. PMID: 37141764, PMCID: PMC10257994, DOI: 10.1016/j.schres.2023.04.010.
• 430. Calibrated fMRI Sensitive to Ketamine-Related Increases Throughout the CortexDriesen N, Herman P, Rowland M, Thompson G, Qiu M, He G, Criscuolo E, Fineberg S, Barron D, Helgeson L, Lacadie C, Chow R, Gueorguieva R, Straun T, Krystal J, Hyder F. 430. Calibrated fMRI Sensitive to Ketamine-Related Increases Throughout the Cortex Biological Psychiatry 2023, 93: s268-s269. DOI: 10.1016/j.biopsych.2023.02.670.
• A Network Investigation of Core Mindfulness ProcessesSala M, Aslan M, Gueorguieva R, Schupak M, Garrison K. A Network Investigation of Core Mindfulness Processes Mindfulness 2023, 14: 992-1004. DOI: 10.1007/s12671-023-02109-4.
• A Network Analysis of Cigarette Craving.Aslan M, Sala M, Gueorguieva R, Garrison K. A Network Analysis of Cigarette Craving. Nicotine & Tobacco Research 2023, 25: 1155-1163. PMID: 36757093, PMCID: PMC10202645, DOI: 10.1093/ntr/ntad021.
• The FIRST nicotine product tried is associated with current multiple nicotine product use and nicotine dependence among a nationally representative sample of U.S. youthsSimon P, Buta E, Jackson A, Camenga D, Kong G, Morean M, Bold K, Davis D, Krishnan-Sarin S, Gueorguieva R. The FIRST nicotine product tried is associated with current multiple nicotine product use and nicotine dependence among a nationally representative sample of U.S. youths Preventive Medicine 2023, 169: 107437. PMID: 36731754, DOI: 10.1016/j.ypmed.2023.107437.
• Examining racial differences in smoking outcomes among smokers enrolled in an intravenous nicotine infusion studySchwartz E, Palmisano A, Gueorguieva R, DeVito E, Sofuoglu M. Examining racial differences in smoking outcomes among smokers enrolled in an intravenous nicotine infusion study Addictive Behaviors 2023, 140: 107615. PMID: 36640662, PMCID: PMC9911383, DOI: 10.1016/j.addbeh.2023.107615.
• Models for Zero-Inflated and Overdispersed Correlated Count Data: An Application to Cigarette Use.Pittman B, Buta E, Garrison K, Gueorguieva R. Models for Zero-Inflated and Overdispersed Correlated Count Data: An Application to Cigarette Use. Nicotine & Tobacco Research 2022, 25: 996-1003. PMID: 36318799, PMCID: PMC10077942, DOI: 10.1093/ntr/ntac253.
• Saracatinib Fails to Reduce Alcohol-Seeking and Consumption in Mice and Human ParticipantsThompson SL, Gianessi CA, O'Malley SS, Cavallo DA, Shi JM, Tetrault JM, DeMartini KS, Gueorguieva R, Pittman B, Krystal JH, Taylor JR, Krishnan-Sarin S. Saracatinib Fails to Reduce Alcohol-Seeking and Consumption in Mice and Human Participants Frontiers In Psychiatry 2021, 12: 709559. PMID: 34531767, PMCID: PMC8438169, DOI: 10.3389/fpsyt.2021.709559.
• Two‐part models for repeatedly measured ordinal data with “don't know” categoryGueorguieva R, Buta E, Morean M, Krishnan‐Sarin S. Two‐part models for repeatedly measured ordinal data with “don't know” category Statistics In Medicine 2020, 39: 4574-4592. PMID: 32909252, PMCID: PMC8025667, DOI: 10.1002/sim.8739.
• Data Visualization Tools of Tobacco Product Use Patterns, Transitions and Sex Differences in the PATH Youth Data.Gueorguieva R, Buta E, Simon P, Krishnan-Sarin S, O’Malley S. Data Visualization Tools of Tobacco Product Use Patterns, Transitions and Sex Differences in the PATH Youth Data. Nicotine & Tobacco Research 2020, 22: 1901-1908. PMID: 32219313, PMCID: PMC7542650, DOI: 10.1093/ntr/ntaa056.
• Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trialKrishnan-Sarin S, O’Malley S, Franco N, Cavallo DA, Tetrault JM, Shi J, Gueorguieva R, Pittman B, Krystal JH. Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial Neuropsychopharmacology 2019, 45: 319-326. PMID: 31590179, PMCID: PMC6901445, DOI: 10.1038/s41386-019-0536-z.
• Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional studyChekroud SR, Gueorguieva R, Zheutlin AB, Paulus M, Krumholz HM, Krystal JH, Chekroud AM. Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study The Lancet Psychiatry 2018, 5: 739-746. PMID: 30099000, DOI: 10.1016/s2215-0366(18)30227-x.
• Bayesian joint modelling of longitudinal data on abstinence, frequency and intensity of drinking in alcoholism trialsButa E, O’Malley S, Gueorguieva R. Bayesian joint modelling of longitudinal data on abstinence, frequency and intensity of drinking in alcoholism trials Journal Of The Royal Statistical Society Series A (Statistics In Society) 2017, 181: 869-888. PMID: 31123390, PMCID: PMC6527419, DOI: 10.1111/rssa.12334.
• Trajectories of relapse in randomised, placebo-controlled trials of treatment discontinuation in major depressive disorder: an individual patient-level data meta-analysisGueorguieva R, Chekroud AM, Krystal JH. Trajectories of relapse in randomised, placebo-controlled trials of treatment discontinuation in major depressive disorder: an individual patient-level data meta-analysis The Lancet Psychiatry 2017, 4: 230-237. PMID: 28189575, PMCID: PMC5340978, DOI: 10.1016/s2215-0366(17)30038-x.
• Statistical Methods in Psychiatry and Related Fields: Longitudinal, Clustered and Other Repeated Measures Data.Gueorguieva R. (2017). Chapman & Hall/CRC Interdisciplinary Statistics series. ISBN 9781498740760.
• Correlated probit analysis of repeatedly measured ordinal and continuous outcomes with application to the Health and Retirement StudyGrigorova D, Gueorguieva R. Correlated probit analysis of repeatedly measured ordinal and continuous outcomes with application to the Health and Retirement Study Statistics In Medicine 2016, 35: 4202-4225. PMID: 27222058, DOI: 10.1002/sim.6982.
• A modified classification tree method for personalized medicine decisions.Tsai WM, Zhang H, Buta E, O'Malley S, Gueorguieva R. A modified classification tree method for personalized medicine decisions. Statistics And Its Interface 2016, 9: 239-253. PMID: 26770292, PMCID: PMC4707681, DOI: 10.4310/sii.2016.v9.n2.a11.
• An analysis of moderators in the COMBINE study: Identifying subgroups of patients who benefit from acamprosateGueorguieva R, Wu R, Tsai WM, O’Connor P, Fucito L, Zhang H, O’Malley S. An analysis of moderators in the COMBINE study: Identifying subgroups of patients who benefit from acamprosate European Neuropsychopharmacology 2015, 25: 1586-1599. PMID: 26141511, PMCID: PMC4600651, DOI: 10.1016/j.euroneuro.2015.06.006.
• Predictors of Abstinence from Heavy Drinking During Treatment in COMBINE and External Validation in PREDICTGueorguieva R, Wu R, O'Connor PG, Weisner C, Fucito LM, Hoffmann S, Mann K, O'Malley SS. Predictors of Abstinence from Heavy Drinking During Treatment in COMBINE and External Validation in PREDICT Alcoholism Clinical And Experimental Research 2014, 38: 2647-2656. PMID: 25346505, PMCID: PMC4397985, DOI: 10.1111/acer.12541.
• Em Algorithm for MLE of a Probit Model for Multiple Ordinal OutcomesGrigorova D, Encheva E, Gueorguieva R. Em Algorithm for MLE of a Probit Model for Multiple Ordinal Outcomes Serdica Journal Of Computing 2014, 7: 227-244. DOI: 10.55630/sjc.2013.7.227-244.
• Temporal patterns of adherence to medications and behavioral treatment and their relationship to patient characteristics and treatment responseGueorguieva R, Wu R, Krystal JH, Donovan D, O'Malley SS. Temporal patterns of adherence to medications and behavioral treatment and their relationship to patient characteristics and treatment response Addictive Behaviors 2013, 38: 2119-2127. PMID: 23435273, PMCID: PMC3595348, DOI: 10.1016/j.addbeh.2013.01.024.
• Random effects models for joint analysis of repeatedly measured discrete and continuous outcomesGueorguieva R. Random effects models for joint analysis of repeatedly measured discrete and continuous outcomes 2013, 109-123. DOI: 10.1201/b14571-9.
• Trajectories of Depression Severity in Clinical Trials of Duloxetine: Insights Into Antidepressant and Placebo ResponsesGueorguieva R, Mallinckrodt C, Krystal JH. Trajectories of Depression Severity in Clinical Trials of Duloxetine: Insights Into Antidepressant and Placebo Responses JAMA Psychiatry 2011, 68: 1227-1237. PMID: 22147842, PMCID: PMC3339151, DOI: 10.1001/archgenpsychiatry.2011.132.
• Joint modelling of longitudinal outcome and interval‐censored competing risk dropout in a schizophrenia clinical trialGueorguieva R, Rosenheck R, Lin H. Joint modelling of longitudinal outcome and interval‐censored competing risk dropout in a schizophrenia clinical trial Journal Of The Royal Statistical Society Series A (Statistics In Society) 2011, 175: 417-433. PMID: 22468033, PMCID: PMC3315284, DOI: 10.1111/j.1467-985x.2011.00719.x.
• Differential changes in body mass index after retirement by occupation: hierarchical modelsGueorguieva R, Sindelar JL, Wu R, Gallo WT. Differential changes in body mass index after retirement by occupation: hierarchical models International Journal Of Public Health 2010, 56: 111-116. PMID: 20625792, PMCID: PMC3154720, DOI: 10.1007/s00038-010-0166-z.
• Correlated Probit ModelGueorguieva R. Correlated Probit Model 2010, 355-362. DOI: 10.3109/9781439822463.057.
• The Impact of Occupation on Self-Rated Health: Cross-Sectional and Longitudinal Evidence from the Health and Retirement SurveyGueorguieva R, Sindelar JL, Falba TA, Fletcher JM, Keenan P, Wu R, Gallo WT. The Impact of Occupation on Self-Rated Health: Cross-Sectional and Longitudinal Evidence from the Health and Retirement Survey The Journals Of Gerontology Series B 2009, 64B: 118-124. PMID: 19196689, PMCID: PMC2654983, DOI: 10.1093/geronb/gbn006.
• Dirichlet component regression and its applications to psychiatric dataGueorguieva R, Rosenheck R, Zelterman D. Dirichlet component regression and its applications to psychiatric data Computational Statistics & Data Analysis 2008, 52: 5344-5355. PMID: 22058582, PMCID: PMC3207324, DOI: 10.1016/j.csda.2008.05.030.
• Length of Prenatal Participation in WIC and Risk of Delivering a Small for Gestational Age Infant: Florida, 1996–2004Gueorguieva R, Morse SB, Roth J. Length of Prenatal Participation in WIC and Risk of Delivering a Small for Gestational Age Infant: Florida, 1996–2004 Maternal And Child Health Journal 2008, 13: 479-488. PMID: 18661219, DOI: 10.1007/s10995-008-0391-8.
• New Insights into the Efficacy of Naltrexone Based on Trajectory-Based Reanalyses of Two Negative Clinical TrialsGueorguieva R, Wu R, Pittman B, Cramer J, Rosenheck RA, O’Malley S, Krystal JH. New Insights into the Efficacy of Naltrexone Based on Trajectory-Based Reanalyses of Two Negative Clinical Trials Biological Psychiatry 2007, 61: 1290-1295. PMID: 17224132, PMCID: PMC1952242, DOI: 10.1016/j.biopsych.2006.09.038.
• Joint analysis of repeatedly observed continuous and ordinal measures of disease severityGueorguieva RV, Sanacora G. Joint analysis of repeatedly observed continuous and ordinal measures of disease severity Statistics In Medicine 2006, 25: 1307-1322. PMID: 16217846, DOI: 10.1002/sim.2270.
• Control Group Bias in Randomized Atypical Antipsychotic Medication Trials for SchizophreniaWoods SW, Gueorguieva RV, Baker CB, Makuch RW. Control Group Bias in Randomized Atypical Antipsychotic Medication Trials for Schizophrenia JAMA Psychiatry 2005, 62: 961-970. PMID: 16143728, DOI: 10.1001/archpsyc.62.9.961.
• Comments about Joint Modeling of Cluster Size and Binary and Continuous Subunit‐Specific OutcomesGueorguieva RV. Comments about Joint Modeling of Cluster Size and Binary and Continuous Subunit‐Specific Outcomes Biometrics 2005, 61: 862-866. PMID: 16135040, DOI: 10.1111/j.1541-020x.2005.00409_1.x.
• Move Over ANOVA: Progress in Analyzing Repeated-Measures Data andIts Reflection in Papers Published in the Archives of General PsychiatryGueorguieva R, Krystal JH. Move Over ANOVA: Progress in Analyzing Repeated-Measures Data andIts Reflection in Papers Published in the Archives of General Psychiatry JAMA Psychiatry 2004, 61: 310-317. PMID: 14993119, DOI: 10.1001/archpsyc.61.3.310.
• A Risk Assessment Screening Test for Very Low Birth WeightGueorguieva RV, Sarkar NP, Carter RL, Ariet M, Roth J, Resnick MB. A Risk Assessment Screening Test for Very Low Birth Weight Maternal And Child Health Journal 2003, 7: 127-136. PMID: 12870628, DOI: 10.1023/a:1023821127953.
• A multivariate generalized linear mixed model for joint modelling of clustered outcomes in the exponential familyGueorguieva R. A multivariate generalized linear mixed model for joint modelling of clustered outcomes in the exponential family Statistical Modelling 2001, 1: 177-193. DOI: 10.1177/1471082x0100100302.
• A Correlated Probit Model for Joint Modeling of Clustered Binary and Continuous ResponsesGueorguieva R, Agresti A. A Correlated Probit Model for Joint Modeling of Clustered Binary and Continuous Responses Journal Of The American Statistical Association 2001, 96: 1102-1112. DOI: 10.1198/016214501753208762.
• Effect of Teenage Pregnancy on Educational Disabilities in KindergartenGueorguieva R, Carter R, Ariet M, Roth J, Mahan C, Resnick M. Effect of Teenage Pregnancy on Educational Disabilities in Kindergarten American Journal Of Epidemiology 2001, 154: 212-220. PMID: 11479185, DOI: 10.1093/aje/154.3.212.
• The Impact of Low Birth Weight, Perinatal Conditions, and Sociodemographic Factors on Educational Outcome in KindergartenResnick M, Gueorguieva R, Carter R, Ariet M, Sun Y, Roth J, Bucciarelli R, Curran J, Mahan C. The Impact of Low Birth Weight, Perinatal Conditions, and Sociodemographic Factors on Educational Outcome in Kindergarten Pediatrics 1999, 104: e74-e74. PMID: 10586008, DOI: 10.1542/peds.104.6.e74.
• Genetic Mapping of 20 Novel Expressed Sequence Tags from Midgestation Mouse Embryos Suggests Chromosomal ClusteringTchernev V, Barbosa M, Detter J, Patel T, Achey K, Wakeland E, Gueorguieva R, Yang M, Gossler A, Kingsmore S. Genetic Mapping of 20 Novel Expressed Sequence Tags from Midgestation Mouse Embryos Suggests Chromosomal Clustering Genomics 1997, 40: 170-174. PMID: 9070936, DOI: 10.1006/geno.1996.4564.