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Nathan Grubaugh, PhD

Associate Professor of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health

Research Summary

Mosquito-borne viruses, such as Zika, West Nile, and chikungunya, continue to emerge into new areas, and sometimes, they surprise us by causing large outbreaks and severe disease. We use genomics to investigate how they spread (genomic epidemiology), cause disease (functional evolution), and adapt to new environments (experimental evolution). Together, these studies can help us better understand and respond to outbreaks. Learn more about our research at


Research Interests

Aedes; Arthropod Vectors; Chikungunya virus; Culex; Dengue Virus; Disease Outbreaks; Epidemiology; Genetics, Microbial; Molecular Sequence Data; RNA Viruses; West Nile virus; Directed Molecular Evolution

Public Health Interests

Emerging Infectious Diseases; Epidemiology Methods; Evolution; Genetics, Genomics, Epigenetics; Global Health; Infectious Diseases; Vector Biology; Mosquito-borne Diseases; COVID-19

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Selected Publications

Clinical Trials

ConditionsStudy Title
COVID-19 Inpatient; COVID-19 Outpatient; Diseases of the Nervous System; HIV/AIDS; Infectious DiseasesHIV Associated Reservoirs and Comorbidities (The HARC Plus Study)