Ning Sun, PhD
Senior Research Scientist in BiostatisticsCards
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Senior Research Scientist in Biostatistics
Biography
Dr. Sun is a Research Scientist in the Department of Biostatistics. She received her B.S. in Civil and Environmental Engineering from Tsinghua University in 1991 and Ph.D. in Environmental Engineering from the University of California at Los Angeles in 1998. Prior to her position at Yale School of Public Health, she was a Postdoctoral Associate and Associate Research Scientist in Chemical Engineering at Yale between 1998 and 2000. Dr. Sun has extensive experiences in environmental engineering focusing on modeling contaminant transport in heterogeneous porous media, and she developed a mathematical and computational approach for colloid surface interactions in Chemical Engineering. As a bioinformatician and biostatistician, Dr. Sun is experienced in statistical methods for transcriptome analysis using both gene expression microarray data and next generation sequencing data, regulatory network modeling, data integration methods, functional genomics, and genome wide association studies. Dr. Sun has developed a number of novel statistical methods for more efficient data integration for the purpose of inferring gene expression networks and disease gene identifications.
Appointments
Biostatistics
Senior Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- University of California at Los Angeles (1998)
- MS
- University of California at Los Angeles (1994)
- BS
- Tsinghua University (1991)
Research
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Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0002-4123-5362
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Hongyu Zhao, PhD
Joel Gelernter, MD
Nallakkandi Rajeevan, PhD
Vasilis Vasiliou, PhD
Daniel F. Levey, PhD
David Thompson
Publications
2025
Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification
Starble R, Sun E, Gbyli R, Radda J, Lu J, Jensen T, Sun N, Khudaverdyan N, Zhao T, Hu B, Melnick M, Zhao S, Roper N, Wang G, Tackett A, Wang Y, Song J, Politi K, Wang S, Xiao A. Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification. Nature Structural & Molecular Biology 2025, 33: 7-19. PMID: 41131337, PMCID: PMC12819156, DOI: 10.1038/s41594-025-01685-4.Peer-Reviewed Original ResearchCitationsAltmetricThe E3 ubiquitin ligase SCFLAO1 promotes NITRITE REDUCTASE degradation to modulate growth and oilseed production in Brassica napus
Li Y, Cheng S, Xu Y, Sun N, Dong J. The E3 ubiquitin ligase SCFLAO1 promotes NITRITE REDUCTASE degradation to modulate growth and oilseed production in Brassica napus. Plant Physiology 2025, 199: kiaf429. PMID: 40994036, DOI: 10.1093/plphys/kiaf429.Peer-Reviewed Original Research
2024
CYP2E1 in 1,4-dioxane metabolism and liver toxicity: insights from CYP2E1 knockout mice study
Wang Y, Charkoftaki G, Orlicky D, Davidson E, Aalizadeh R, Sun N, Ginsberg G, Thompson D, Vasiliou V, Chen Y. CYP2E1 in 1,4-dioxane metabolism and liver toxicity: insights from CYP2E1 knockout mice study. Archives Of Toxicology 2024, 98: 3241-3257. PMID: 39192018, PMCID: PMC11500436, DOI: 10.1007/s00204-024-03811-5.Peer-Reviewed Original ResearchCitationsAltmetricLong-term exposure to ambient fine particulate matter and risk of liver cancer in the NIH-AARP Diet and Health Study
Ma X, Fisher J, McGlynn K, Liao L, Vasiliou V, Sun N, Kaufman J, Silverman D, Jones R. Long-term exposure to ambient fine particulate matter and risk of liver cancer in the NIH-AARP Diet and Health Study. Environment International 2024, 187: 108637. PMID: 38636274, PMCID: PMC11286199, DOI: 10.1016/j.envint.2024.108637.Peer-Reviewed Original ResearchCitationsAltmetricTemporal control of the Aux/IAA genes BnIAA32 and BnIAA34 mediates Brassica napus dual shade responses
Li Y, Guo Y, Cao Y, Xia P, Xu D, Sun N, Jiang L, Dong J. Temporal control of the Aux/IAA genes BnIAA32 and BnIAA34 mediates Brassica napus dual shade responses. Journal Of Integrative Plant Biology 2024, 66: 928-942. PMID: 37929685, DOI: 10.1111/jipb.13582.Peer-Reviewed Original ResearchCitationsAltmetric
2023
Ambient fine particulate matter exposure and risk of incident liver cancer in the NIH-AARP Diet and Health Study
Ma X, Fisher J, McGlynn K, Liao L, Vasiliou V, Sun N, Kaufman J, Silverman D, Jones R. Ambient fine particulate matter exposure and risk of incident liver cancer in the NIH-AARP Diet and Health Study. ISEE Conference Abstracts 2023, 2023 DOI: 10.1289/isee.2023.vo-011.Peer-Reviewed Original ResearchEffects of surface roughness on van der Waals and electrostatic contributions to particle-particle interactions and particle adhesion
Walz J, Sun N. Effects of surface roughness on van der Waals and electrostatic contributions to particle-particle interactions and particle adhesion. 2023, 151-169. DOI: 10.1201/9780429070716-11.ChaptersCitations
2022
Use of clinical chemistry health outcomes and PFAS chain length to predict 28-day rodent oral toxicity
Bellia G, Bilott R, Sun N, Thompson D, Vasiliou V. Use of clinical chemistry health outcomes and PFAS chain length to predict 28-day rodent oral toxicity. Toxicology Methods 2022, 33: 378-387. PMID: 36446747, PMCID: PMC10625160, DOI: 10.1080/15376516.2022.2150591.Peer-Reviewed Original ResearchCitationsAltmetric
2020
Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals
Xu K, Li B, McGinnis KA, Vickers-Smith R, Dao C, Sun N, Kember RL, Zhou H, Becker WC, Gelernter J, Kranzler HR, Zhao H, Justice AC. Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals. Nature Communications 2020, 11: 5302. PMID: 33082346, PMCID: PMC7598939, DOI: 10.1038/s41467-020-18489-3.Peer-Reviewed Original ResearchCitationsAltmetricStatistical Methods in Genome-Wide Association Studies
Sun N, Zhao H. Statistical Methods in Genome-Wide Association Studies. Annual Review Of Biomedical Data Science 2020, 3: 1-24. DOI: 10.1146/annurev-biodatasci-030320-041026.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitations
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