2021
Analysis of Health Trajectories Leading to Adverse Opioid-Related Events.
Gilson AS, Chartash D, Chang D, Hawk K, D'Onofrio G, Haimovich AD, Fiellin DA, Taylor RA. Analysis of Health Trajectories Leading to Adverse Opioid-Related Events. AMIA Joint Summits On Translational Science Proceedings 2021, 2021: 248-256. PMID: 34457139, PMCID: PMC8378649.Peer-Reviewed Original ResearchConceptsRelative riskHealth trajectoriesHealth service eventsPatient risk factorsMental health diagnosesHigher relative riskLargest relative riskCombination of diagnosisViral hepatitisPatient cohortRisk factorsRisk-based interventionsMental health codesNatural historyPatient diagnosisHealth diagnosisDiagnosisTherapy agentsPotential causal mechanismsRiskAverage populationAOEHealth CodeHepatitisOpioids
1994
The lack of efficacy of phenytoin in the prevention of recurrent alcohol-related seizures
Rathlev N, D'Onofrio G, Fish S, Harrison P, Bernstein E, Hossack R, Pickens L. The lack of efficacy of phenytoin in the prevention of recurrent alcohol-related seizures. Annals Of Emergency Medicine 1994, 23: 513-518. PMID: 8135426, DOI: 10.1016/s0196-0644(94)70070-2.Peer-Reviewed Original ResearchConceptsAlcohol-related seizuresSix-hour observation periodNormal saline placeboDouble-blind trialObservation periodConfidence intervalsLack of efficacyChronic alcohol abuseYears of ageChi 2 analysisPlacebo groupConsecutive adultsEligible subjectsPhenytoin groupSaline placeboGeneralized seizuresPhenytoin administrationSecond seizureEmergency departmentNormal salineRelative riskTeaching hospitalAlcohol abuseDrug AdministrationSeizures