Clonal gene signatures predict prognosis in mesothelioma and lung adenocarcinoma
Lin Y, Burt B, Lee H, Nguyen T, Jang H, Lee C, Hong W, Ripley R, Amos C, Cheng C. Clonal gene signatures predict prognosis in mesothelioma and lung adenocarcinoma. Npj Precision Oncology 2024, 8: 47. PMID: 38396241, PMCID: PMC10891127, DOI: 10.1038/s41698-024-00531-y.Peer-Reviewed Original ResearchMalignant pleural mesotheliomaMalignant pleural mesothelioma patientsIntratumoral heterogeneityTranscriptome dataPrognostic stratificationPrognostic valueLung adenocarcinomaRNA-seq dataRNA-seq datasetsGene signatureCopy number variationsCancer typesAssociated with poor prognosisLow intratumoral heterogeneityGenomic regionsNumber variationsPleural mesotheliomaPoor prognosisClinical factorsTumor samplesInferior regionsGenesPrognostic genesTumorCancer