Tissue-resident memory T cell signatures from single-cell analysis associated with better melanoma prognosis
Jiang C, Chao C, Li J, Ge X, Shen A, Jucaud V, Cheng C, Shen X. Tissue-resident memory T cell signatures from single-cell analysis associated with better melanoma prognosis. IScience 2024, 27: 109277. PMID: 38455971, PMCID: PMC10918229, DOI: 10.1016/j.isci.2024.109277.Peer-Reviewed Original ResearchTumor immune microenvironmentTissue-resident memory TMemory TOverall survivalT cellsAssociated with longer overall survivalT cell-mediated responsesLonger overall survivalMemory B cellsT cell populationsAbundance of T cellsCell-mediated responsesHigh-risk categoryMelanoma patientsNK cellsImmune microenvironmentPatient survivalMelanoma prognosisImmune activationB cellsM1 macrophagesPeripheral tissuesRisk scoreCell populationsPatients