Zhangsheng Yu
Professor Adjunct of BiostatisticsCards
About
Research
Publications
2026
Foundation Models in Urological Pathology: Possible Impact and Potential Pitfalls
Zhu X, Liu Q, Xia Y, Zhang Q, Yu Z, Cheng L, Chen R. Foundation Models in Urological Pathology: Possible Impact and Potential Pitfalls. Asian Journal Of Urology 2026 DOI: 10.1016/j.ajur.2026.01.007.Commentaries, Editorials and LettersSemi-automatic mask guidance enhances 3D tumor segmentation in medical imaging
Zhang Y, Xia Y, Wang Y, Xun X, Gao R, Yin J, Gong Y, Zhao S, Zhang J, Yu Z. Semi-automatic mask guidance enhances 3D tumor segmentation in medical imaging. Communications Medicine 2026, 6: 527. PMID: 42337366, PMCID: PMC13655109, DOI: 10.1038/s43856-026-01735-y.Peer-Reviewed Original ResearchEvaluating the Effectiveness of an Enhanced Early Childhood Development Program Integrated Into Primary Health Care in China: Protocol for a Cluster Randomized Controlled Trial
Zhang Y, Dong Y, Wang H, Zhou H, Li G, Dong Z, Jiao J, Wu Y, Qi S, Yu Z, Wei X, Jiang F. Evaluating the Effectiveness of an Enhanced Early Childhood Development Program Integrated Into Primary Health Care in China: Protocol for a Cluster Randomized Controlled Trial. JMIR Research Protocols 2026, 15: e89106. PMID: 42202312, PMCID: PMC13215665, DOI: 10.2196/89106.Peer-Reviewed Original ResearchEmpowering multifaceted analysis of spatial transcriptomics data with RGAST
Gong Y, Yuan X, Yu Z. Empowering multifaceted analysis of spatial transcriptomics data with RGAST. Briefings In Bioinformatics 2026, 27: bbag298. PMID: 42302280, PMCID: PMC13271401, DOI: 10.1093/bib/bbag298.Peer-Reviewed Original ResearchMeta-encoder: a unified integration framework for multiple pathological foundation models in cancer detection
Gao R, Yang Z, Yuan X, Wang Y, Xia Y, Zhang Y, Zheng B, Gong Y, Yue Y, Tu Y, Yu Z. Meta-encoder: a unified integration framework for multiple pathological foundation models in cancer detection. Nature Communications 2026, 17: 5738. PMID: 41986341, PMCID: PMC13323401, DOI: 10.1038/s41467-026-71558-x.Peer-Reviewed Original ResearchEarly lumbar drainage plus intrathecal urokinase in severe aneurysmal subarachnoid hemorrhage: the LD-ITUK randomized controlled trial protocol
Wu M, Yan T, Hu P, Wang C, Ye M, Yu Z, Wang Y, Mao G, Xiao B, Gong Y, Li J, Zhao R, Yang P, Liu J, Zhu X. Early lumbar drainage plus intrathecal urokinase in severe aneurysmal subarachnoid hemorrhage: the LD-ITUK randomized controlled trial protocol. Trials 2026, 27: 379. PMID: 41968344, PMCID: PMC13182107, DOI: 10.1186/s13063-026-09716-1.Peer-Reviewed Original ResearchAdultCombined Modality TherapyDouble-Blind MethodDrainageEquivalence Trials as TopicFibrinolytic AgentsHumansInjections, SpinalMulticenter Studies as TopicProspective StudiesRandomized Controlled Trials as TopicSeverity of Illness IndexSubarachnoid HemorrhageTime FactorsTreatment OutcomeUrokinase-Type Plasminogen ActivatorA Bayesian phase I/II platform design with data augmentation accounting for delayed outcomes
Yang W, Mu R, Yu Z. A Bayesian phase I/II platform design with data augmentation accounting for delayed outcomes. Biometrics 2026, 82: ujag096. PMID: 42319384, DOI: 10.1093/biomtc/ujag096.Peer-Reviewed Original ResearchSurvSTAAR: A Powerful Statistical Framework for Rare Variant Analysis of Time-to-Event Traits in Large-Scale Whole-Genome Sequencing Studies
Cui Y, Ma S, Yuan Y, Zhu N, Chen H, Wei T, Li Z, Li X, Yu Z. SurvSTAAR: A Powerful Statistical Framework for Rare Variant Analysis of Time-to-Event Traits in Large-Scale Whole-Genome Sequencing Studies. Journal Of The American Statistical Association 2026, 121: 905-916. DOI: 10.1080/01621459.2025.2606388.Peer-Reviewed Original ResearchRetinal structure and microcirculation alterations in dysthyroid optic neuropathy: A comprehensive OCTA study
Tan K, Liu Y, Zhang Y, Chen X, Li J, Wang H, Wu S, Feng M, Xi C, Sun Q, Sun J, Li Y, Yu Z, Zhou H, Fan X. Retinal structure and microcirculation alterations in dysthyroid optic neuropathy: A comprehensive OCTA study. Asia-Pacific Journal Of Ophthalmology 2026, 15: 100303. PMID: 41833634, DOI: 10.1016/j.apjo.2026.100303.Peer-Reviewed Original ResearchLeveraging co-attention-based interactions between pathology and radiology for pan-cancer survival prediction
Xia Y, Zhou J, Wang M, Hu T, Zhai W, Zhang Y, Yu Z. Leveraging co-attention-based interactions between pathology and radiology for pan-cancer survival prediction. Computerized Medical Imaging And Graphics 2026, 130: 102744. PMID: 41806501, DOI: 10.1016/j.compmedimag.2026.102744.Peer-Reviewed Original Research