2016
Whole genome sequencing shows sleeping sickness relapse is due to parasite regrowth and not reinfection
Richardson JB, Evans B, Pyana PP, Van Reet N, Sistrom M, Büscher P, Aksoy S, Caccone A. Whole genome sequencing shows sleeping sickness relapse is due to parasite regrowth and not reinfection. Evolutionary Applications 2016, 9: 381-393. PMID: 26834831, PMCID: PMC4721075, DOI: 10.1111/eva.12338.Peer-Reviewed Original ResearchSame patientHuman African trypanosomiasisHigh incidencePatientsTrypanosoma brucei gambienseHAT casesDrug resistanceDisease controlRelapseSingle nucleotide polymorphismsBrucei gambienseWhole-genome sequencingAfrican trypanosomiasisPathogenic levelsSaharan AfricaNucleotide polymorphismsOriginal strainRecent studiesTreatmentPromising new setFunctional studiesNovel insightsReinfectionFuture functional studiesNew strain
2002
Speciation Within Anopheles gambiae-- the Glass Is Half Full
della Torre A, Costantini C, Besansky N, Caccone A, Petrarca V, Powell J, Coluzzi M. Speciation Within Anopheles gambiae-- the Glass Is Half Full. Science 2002, 298: 115-117. PMID: 12364784, DOI: 10.1126/science.1078170.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalAfrica South of the SaharaAllelesAnimalsAnophelesBiological EvolutionChromosome InversionChromosomesDNA, RibosomalEcosystemEnvironmentFeeding BehaviorGenetic VariationGenetics, PopulationGenomeHuman ActivitiesHumansInsect Bites and StingsInsect VectorsMalariaMicrosatellite RepeatsReproductionSequence Analysis, DNA