Women's Health in the Time of COVID-19 Webinar
Uncovering how the coronavirus affects the biology of women and men differently is teaching us new ways to fight COVID-19. Identifying how the stress of the pandemic is different for women and men is focusing mental health professionals on risk and resilience. Watch Women’s Health Research at Yale Director Carolyn M. Mazure, Ph.D, and leading immunologist Akiko Iwasaki, Ph.D., in conversation with Yale Medalist Susanna Krentz, '80, as they discuss a major new research finding and next steps in investigating sex differences to advance the health of women and men.
New cancer immunotherapy drugs rapidly reach patients after approval
The majority of patients eligible for cancer immunotherapy drugs known as checkpoint inhibitors received treatment within a few months of FDA approval, according to a new Yale-led study. The finding suggests that cancer immunotherapies are adopted at a much quicker pace than is typical for newly approved medical treatments, the researchers said. However, patients receiving the therapies are older than those in the clinical trials used to evaluate them, pointing to a disconnect between research and practice that should be addressed, they noted.
Researchers develop a novel RNA-based therapy to target West Nile Virus
A Yale-led research team developed a new RNA therapy, delivered through the nose, to treat mice infected with West Nile Virus. The innovative approach reduced the virus in the brain, allowing the immune system to destroy the virus and develop long-term protection against West Nile Virus disease, the researchers said.
Opportunities to vaccinate young women against HPV missed at alarming rate
en aged 18-26 who were eligible to receive Human Papilloma Virus (HPV) vaccine have missed at least one opportunity to receive the vaccine during a visit to an obstetrics and gynecology clinic, Yale researchers report. This study also confirms previous research showing racial disparities in vaccination for HPV: Women who identify as black are 61% more likely have had a missed opportunity than women who identify as white. These findings are published in the American Journal of Obstetrics and Gynecology. HPV is a well-known cause of pre-cancerous cervical lesions, which, if untreated, could develop into cervical cancer. Immunization against HPV has been shown to be safe and effective in preventing these pre-cancerous lesions. The two-dose HPV vaccine is recommended for administration to It is recommended that girls ages 11-12 receive the two-dose HPV vaccine, and that those through age 26 receive the three-dose vaccination for “catch-up.”
Aging impairs innate immune response to flu
Aging impairs the immune system’s response to the flu virus in multiple ways, weakening resistance in older adults, according to a Yale study. The research reveals why older people are at increased risk of illness and death from flu, the researchers said.
Digestion Could Account for Differences in Colon Cancer Among Men, Women
Although women are less likely to develop colon cancer than men, they have higher rates of right-sided colon cancer, which is linked to worse outcomes since it is close in proximity to the small intestine. Colorectal cancer results in more than 50,000 people each year, and is a leading cause of death for both sexes. While this cancer is avoidable through a healthy diet, many Americans develop this cancer each year. A new study being conducted by the Yale Cancer Center suggests that digestion differences could result in sex disparities for colon cancer, according to a press release.Source: Specialty Pharmacy Times
Social contagion in the exam room: Peer influence and cancer surgeons’ use of breast MRI
A new study by researchers at Yale School of Medicine and Johns Hopkins School of Medicine has found that surgeons’ use of a new imaging test is influenced by the practice style of their peers. Published in the current issue of the Journal of the National Cancer Institute, the study suggests that social contagion — which has largely been studied in the field of sociology as a means by which ideas, attitudes, and behaviors spread — is also a relevant factor in medicine.
Zika virus harms testes, says study
The Zika virus reduces the size of testes in infected mice up to 21 days after infection, according to a new Yale study. The persistence of the virus in the male reproductive organ can lead to sexual transmission and may impair male fertility, the researchers said.
Using the Immune System to Target Cancer
A former Navy pilot, Ray leads an active life and was anxious to return to his usual level of activity. He was totally blindsided when he received a diagnosis of lung cancer, and further devastated by the news that it had spread to his pancreas and possibly his brain. He learned he was eligible for a clinical trial to test pembrolizumab, a drug helps the immune system fight cancer by blocking a pathway that prevents immune cells from destroying cancer cells.
Eleven Yale faculty honored by Connecticut Academy of Science and Engineering
Eleven Yale faculty are among 23 individuals recently elected to the Connecticut Academy of Science and Engineering. Members of the academy are considered Connecticut's leading experts in science, engineering, and technology.
Broad immune response may be needed to destroy latent HIV
A major barrier to finding a cure for HIV/AIDS is the presence of latent HIV in the cells of chronically infected individuals. But a team of Yale and Johns Hopkins researchers may have pinpointed a strategy for eliminating the residual virus.
Cold virus replicates better at cooler temperatures
The common cold virus can reproduce itself more efficiently in the cooler temperature found inside the nose than at core body temperature, according to a new Yale-led study. This finding may confirm the popular, yet contested, notion that people are more likely to catch a cold in cool-weather conditions.
President and professor — Salovey and Medzhitov — elected to Institute of Medicine
Yale President Peter Salovey and immunologist Ruslan Medzhitov of the Yale School of Medicine, have been elected as new members of the Institute of Medicine (IOM), one of the most prestigious bodies in health and medicine.
Blavatnik Family Foundation to provide $10 million grant for immunobiology research at Yale
Scientists at Yale University will test a new theory of inflammation and chronic disease, thanks to a $10 million grant from the Blavatnik Family Foundation, the charitable organization headed by American industrialist and philanthropist Len Blavatnik. The grant supports the work of immunobiologists Ruslan Medzhitov and Richard Flavell, who have posed a unifying theory to describe how inflammation can impact the body’s homeostatic control mechanisms to trigger the onset of disease.