Deus Thindwa, PhD
Postdoctoral Associate
Research & Publications
Biography
Locations
Coauthors
Selected Publications
- Cost-effectiveness analysis of typhoid conjugate vaccines in an outbreak setting: a modeling studyPhillips M, Antillon M, Bilcke J, Bar-Zeev N, Limani F, Debellut F, Pecenka C, Neuzil K, Gordon M, Thindwa D, Paltiel A, Yaesoubi R, Pitzer V. Cost-effectiveness analysis of typhoid conjugate vaccines in an outbreak setting: a modeling study. BMC Infectious Diseases 2023, 23: 143. PMID: 36890448, PMCID: PMC9993384, DOI: 10.1186/s12879-023-08105-2.
- Optimal age targeting for pneumococcal vaccination in older adults; a modelling study.Thindwa D, Clifford S, Kleynhans J, von Gottberg A, Walaza S, Meiring S, Swarthout TD, Miller E, McIntyre P, Andrews N, Amin-Chowdhury Z, Fry N, Jambo KC, French N, Almeida SCG, Ladhani SN, Heyderman RS, Cohen C, de Cunto Brandileone MC, Flasche S. Optimal age targeting for pneumococcal vaccination in older adults; a modelling study. Nat Commun 2023, 14: 888. PMID: 36797259, DOI: 10.1038/s41467-023-36624-8.
- Unmasking Pneumococcal Carriage in a High Human Immunodeficiency Virus (HIV) Prevalence Population in two Community Cohorts in South Africa, 2016-2018: The PHIRST Study.Carrim M, Tempia S, Thindwa D, Martinson NA, Kahn K, Flasche S, Hellferscee O, Treurnicht FK, McMorrow ML, Moyes J, Mkhencele T, Mathunjwa A, Kleynhans J, Lebina L, Mothlaoleng K, Wafawanaka F, Gómez-Olivé FX, Cohen C, von Gottberg A, Wolter N, PHIRST group. Unmasking Pneumococcal Carriage in a High Human Immunodeficiency Virus (HIV) Prevalence Population in two Community Cohorts in South Africa, 2016-2018: The PHIRST Study. Clin Infect Dis 2023, 76: e710-e717. PMID: 35717655, DOI: 10.1093/cid/ciac499.
- Omicron B.1.1.529 variant infections associated with severe disease are uncommon in a COVID-19 under-vaccinated, high SARS-CoV-2 seroprevalence population in Malawi.Mseka UL, Mandolo J, Nyoni K, Divala O, Kambalame D, Mapemba D, Kamzati M, Chibwe I, Henrion MYR, Manda K, Thindwa D, Mvula M, Odala B, Kamng'ona R, Dzinza N, Jere KC, Feasey N, Ho A, Amoah AS, Gordon M, Swarthout TD, Crampin A, Heyderman RS, Kagoli M, Chitsa-Banda E, Mitambo C, Phuka J, Chilima B, Kasambara W, Jambo KC, Chauma-Mwale A. Omicron B.1.1.529 variant infections associated with severe disease are uncommon in a COVID-19 under-vaccinated, high SARS-CoV-2 seroprevalence population in Malawi. EClinicalMedicine 2023, 56: 101800. PMID: 36600885, DOI: 10.1016/j.eclinm.2022.101800.
- Waning of antibody levels induced by a 13-valent pneumococcal conjugate vaccine, using a 3 + 0 schedule, within the first year of life among children younger than 5 years in Blantyre, Malawi: an observational, population-level, serosurveillance study.Swarthout TD, Henrion MYR, Thindwa D, Meiring JE, Mbewe M, Kalizang'Oma A, Brown C, Msefula J, Moyo B, Mataya AA, Barnaba S, Pearce E, Gordon M, Goldblatt D, French N, Heyderman RS. Waning of antibody levels induced by a 13-valent pneumococcal conjugate vaccine, using a 3 + 0 schedule, within the first year of life among children younger than 5 years in Blantyre, Malawi: an observational, population-level, serosurveillance study. Lancet Infect Dis 2022, 22: 1737-1747. PMID: 36029796, DOI: 10.1016/S1473-3099(22)00438-8.
- Quality of antibody responses by adults and young children to 13-valent pneumococcal conjugate vaccination and Streptococcus pneumoniae colonisation.Wolf AS, Mitsi E, Jones S, Jochems SP, Roalfe L, Thindwa D, Meiring JE, Msefula J, Bonomali F, Makhaza Jere T, Mbewe M, Collins AM, Gordon SB, Gordon MA, Ferreira DM, French N, Goldblatt D, Heyderman RS, Swarthout TD. Quality of antibody responses by adults and young children to 13-valent pneumococcal conjugate vaccination and Streptococcus pneumoniae colonisation. Vaccine 2022, 40: 7201-7210. PMID: 36210249, DOI: 10.1016/j.vaccine.2022.09.069.
- Risk factors for pneumococcal carriage in adults living with HIV on antiretroviral therapy in the infant pneumococcal vaccine era in Malawi.Thindwa D, Mwalukomo TS, Msefula J, Jambo KC, Brown C, Kamng'ona A, Mwansambo C, Ojal J, Flasche S, French N, Heyderman RS, Swarthout TD. Risk factors for pneumococcal carriage in adults living with HIV on antiretroviral therapy in the infant pneumococcal vaccine era in Malawi. AIDS 2022, 36: 2045-2055. PMID: 35983828, DOI: 10.1097/QAD.0000000000003365.
- Hepatitis B Vaccination Impact and the Unmet Need for Antiviral Treatment in Blantyre, Malawi.Stockdale AJ, Meiring JE, Shawa IT, Thindwa D, Silungwe NM, Mbewe M, Kachala R, Kreuels B, Patel P, Patel P, Henrion MYR, Bar-Zeev N, Swarthout TD, Heyderman RS, Gordon SB, Maria Geretti A, Gordon MA. Hepatitis B Vaccination Impact and the Unmet Need for Antiviral Treatment in Blantyre, Malawi. J Infect Dis 2022, 226: 871-880. PMID: 34752631, DOI: 10.1093/infdis/jiab562.
- Effect of patient-delivered household contact tracing and prevention for tuberculosis: A household cluster-randomised trial in MalawiKaswaswa K, MacPherson P, Kumwenda M, Mpunga J, Thindwa D, Nliwasa M, Mwapasa M, Odland J, Tomoka T, Chipungu G, Mukaka M, Corbett E. Effect of patient-delivered household contact tracing and prevention for tuberculosis: A household cluster-randomised trial in Malawi. PLOS ONE 2022, 17: e0269219. PMID: 36074775, PMCID: PMC9455850, DOI: 10.1371/journal.pone.0269219.
- Social mixing patterns relevant to infectious diseases spread by close contact in urban Blantyre, MalawiThindwa D, Jambo K, Ojal J, MacPherson P, Dennis Phiri M, Pinsent A, Khundi M, Chiume L, Gallagher K, Heyderman R, Corbett E, French N, Flasche S. Social mixing patterns relevant to infectious diseases spread by close contact in urban Blantyre, Malawi. Epidemics 2022, 40: 100590. PMID: 35691100, PMCID: PMC9176177, DOI: 10.1016/j.epidem.2022.100590.
- Estimating the contribution of HIV-infected adults to household pneumococcal transmission in South Africa, 2016-2018: A hidden Markov modelling study.Thindwa D, Wolter N, Pinsent A, Carrim M, Ojal J, Tempia S, Moyes J, McMorrow M, Kleynhans J, Gottberg AV, French N, PHIRST group, Cohen C, Flasche S. Estimating the contribution of HIV-infected adults to household pneumococcal transmission in South Africa, 2016-2018: A hidden Markov modelling study. PLoS Comput Biol 2021, 17: e1009680. PMID: 34941865, DOI: 10.1371/journal.pcbi.1009680.
- Burden of enteric fever at three urban sites in Africa and Asia: a multicentre population-based studyMeiring JE, Shakya M, Khanam F, Voysey M, Phillips MT, Tonks S, Thindwa D, Darton TC, Dongol S, Karkey A, Zaman K, Baker S, Dolecek C, Dunstan SJ, Dougan G, Holt KE, Heyderman RS, Qadri F, Pitzer VE, Basnyat, Gordon MA, Clemens J, Pollard AJ, Group S. Burden of enteric fever at three urban sites in Africa and Asia: a multicentre population-based study. The Lancet Global Health 2021, 9: e1688-e1696. PMID: 34798028, PMCID: PMC8609278, DOI: 10.1016/s2214-109x(21)00370-3.
- A Bayesian approach for estimating typhoid fever incidence from large‐scale facility‐based passive surveillance dataPhillips MT, Meiring JE, Voysey M, Warren JL, Baker S, Basnyat, Clemens JD, Dolecek C, Dunstan SJ, Dougan G, Gordon MA, Thindwa D, Heyderman RS, Holt KE, Qadri F, Pollard AJ, Pitzer VE, Group T. A Bayesian approach for estimating typhoid fever incidence from large‐scale facility‐based passive surveillance data. Statistics In Medicine 2021, 40: 5853-5870. PMID: 34428309, PMCID: PMC9291985, DOI: 10.1002/sim.9159.
- Tuberculosis case notifications in Malawi have strong seasonal and weather-related trendsKirolos A, Thindwa D, Khundi M, Burke R, Henrion M, Nakamura I, Divala T, Nliwasa M, Corbett E, MacPherson P. Tuberculosis case notifications in Malawi have strong seasonal and weather-related trends. Scientific Reports 2021, 11: 4621. PMID: 33633272, PMCID: PMC7907065, DOI: 10.1038/s41598-021-84124-w.
- Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia.Thindwa D, Farooq YG, Shakya M, Saha N, Tonks S, Anokwa Y, Gordon MA, Hartung C, Meiring JE, Pollard AJ, Heyderman RS, Strategic Typhoid alliance across Africa and Asia consortium. Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia. Wellcome Open Res 2020, 5: 66. PMID: 32934993, DOI: 10.12688/wellcomeopenres.15811.2.
- Vaccine strategies to reduce the burden of pneumococcal disease in HIV-infected adults in Africa.Thindwa D, Pinsent A, Ojal J, Gallagher KE, French N, Flasche S. Vaccine strategies to reduce the burden of pneumococcal disease in HIV-infected adults in Africa. Expert Rev Vaccines 2020, 19: 1085-1092. PMID: 33269987, DOI: 10.1080/14760584.2020.1843435.
- Use of seasonal influenza and pneumococcal polysaccharide vaccines in older adults to reduce COVID-19 mortality.Thindwa D, Garcia Quesada M, Liu Y, Bennett J, Cohen C, Knoll MD, von Gottberg A, Hayford K, Flasche S. Use of seasonal influenza and pneumococcal polysaccharide vaccines in older adults to reduce COVID-19 mortality. Vaccine 2020, 38: 5398-5401. PMID: 32600911, DOI: 10.1016/j.vaccine.2020.06.047.
- Distinct climate influences on the risk of typhoid compared to invasive non-typhoid Salmonella disease in Blantyre, Malawi.Thindwa D, Chipeta MG, Henrion MYR, Gordon MA. Distinct climate influences on the risk of typhoid compared to invasive non-typhoid Salmonella disease in Blantyre, Malawi. Sci Rep 2019, 9: 20310. PMID: 31889080, DOI: 10.1038/s41598-019-56688-1.
- Pregnancy intention and contraceptive use among HIV-positive Malawian women at 4-26 weeks post-partum: A nested cross-sectional study.Thindwa D, Landes M, van Lettow M, Kanyemba A, Nkhoma E, Phiri H, Kalua T, van Oosterhout JJ, Kim EJ, Barr BAT, NEMAPP Consortium. Pregnancy intention and contraceptive use among HIV-positive Malawian women at 4-26 weeks post-partum: A nested cross-sectional study. PLoS One 2019, 14: e0215947. PMID: 31013338, DOI: 10.1371/journal.pone.0215947.
- Completion of isoniazid preventive therapy among human immunodeficiency virus positive adults in urban MalawiThindwa D, MacPherson P, Choko A, Khundi M, Sambakunsi R, Ngwira L, Kalua T, Webb E, Corbett E. Completion of isoniazid preventive therapy among human immunodeficiency virus positive adults in urban Malawi. The International Journal Of Tuberculosis And Lung Disease 2018, 22: 273-279. PMID: 29471904, PMCID: PMC5824849, DOI: 10.5588/ijtld.17.0370.
- The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveysDarton TC, Meiring JE, Tonks S, Khan MA, Khanam F, Shakya M, Thindwa D, Baker S, Basnyat B, Clemens JD, Dougan G, Dolecek C, Dunstan SJ, Gordon MA, Heyderman RS, Holt KE, Pitzer VE, Qadri F, Zaman K, Pollard AJ. The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys. BMJ Open 2017, 7: e016283. PMID: 28674145, PMCID: PMC5726077, DOI: 10.1136/bmjopen-2017-016283.
- Initial Accuracy of HIV Rapid Test Kits Stored in Suboptimal Conditions and Validity of Delayed Reading of Oral Fluid TestsChoko A, Taegtmeyer M, MacPherson P, Cocker D, Khundi M, Thindwa D, Sambakunsi R, Kumwenda M, Chiumya K, Malema O, Makombe S, Webb E, Corbett E. Initial Accuracy of HIV Rapid Test Kits Stored in Suboptimal Conditions and Validity of Delayed Reading of Oral Fluid Tests. PLOS ONE 2016, 11: e0158107. PMID: 27336161, PMCID: PMC4918937, DOI: 10.1371/journal.pone.0158107.
- Effect of Optional Home Initiation of HIV Care Following HIV Self-testing on Antiretroviral Therapy Initiation Among Adults in Malawi: A Randomized Clinical TrialMacPherson P, Lalloo D, Webb E, Maheswaran H, Choko A, Makombe S, Butterworth A, van Oosterhout J, Desmond N, Thindwa D, Squire S, Hayes R, Corbett E. Effect of Optional Home Initiation of HIV Care Following HIV Self-testing on Antiretroviral Therapy Initiation Among Adults in Malawi: A Randomized Clinical Trial. JAMA 2014, 312: 372-379. PMID: 25038356, PMCID: PMC4118051, DOI: 10.1001/jama.2014.6493.
- A Novel Community Health Worker Tool Outperforms WHO Clinical Staging for Assessment of Antiretroviral Therapy Eligibility in a Resource-Limited SettingMacPherson P, Lalloo D, Thindwa D, Webb E, Squire S, Chipungu G, Desmond N, Makombe S, Taegtmeyer M, Choko A, Corbett E. A Novel Community Health Worker Tool Outperforms WHO Clinical Staging for Assessment of Antiretroviral Therapy Eligibility in a Resource-Limited Setting. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 65: e74-e78. PMID: 23846567, PMCID: PMC3966510, DOI: 10.1097/qai.0b013e3182a20e74.
- Development and Validation of a Global Positioning System–based “Map Book” System for Categorizing Cluster Residency Status of Community Members Living in High-Density Urban Slums in Blantyre, MalawiMacPherson P, Choko A, Webb E, Thindwa D, Squire S, Sambakunsi R, van Oosterhout J, Chunda T, Chavula K, Makombe S, Lalloo D, Corbett E. Development and Validation of a Global Positioning System–based “Map Book” System for Categorizing Cluster Residency Status of Community Members Living in High-Density Urban Slums in Blantyre, Malawi. American Journal Of Epidemiology 2013, 177: 1143-1147. PMID: 23589586, PMCID: PMC3649638, DOI: 10.1093/aje/kws376.
- Determinants and Consequences of Failure of Linkage to Antiretroviral Therapy at Primary Care Level in Blantyre, Malawi: A Prospective Cohort StudyMacPherson P, Corbett E, Makombe S, van Oosterhout J, Manda E, Choko A, Thindwa D, Squire S, Mann G, Lalloo D. Determinants and Consequences of Failure of Linkage to Antiretroviral Therapy at Primary Care Level in Blantyre, Malawi: A Prospective Cohort Study. PLOS ONE 2012, 7: e44794. PMID: 22984560, PMCID: PMC3439373, DOI: 10.1371/journal.pone.0044794.