YSPH Biostatistics Seminar: “Analysis of Complex Multilevel Dental Data with Informative Tooth Loss”

NOTE: BIS 525 students are required to attend in person. Others are invited to attend in person, but may also attend via Zoom.

SPEAKER: Aya Mitani, PhD, Assistant Professor, Department of Biostatistics, University of Toronto

TITLE: "Analysis of Complex Multilevel Dental Data with Informative Tooth Loss"

ABSTRACT: Almost half of the global adult population suffers from gum disease, which, if untreated, can lead to tooth loss. When the unit of analysis is the tooth, we need to account for the baseline number of teeth and the rate of tooth loss over time when analyzing the marginal effect of health risk factors on changing gum disease outcomes over time. I will present two recent works on methods to model complex longitudinal dental data subject to informative cluster size. One incorporates inverse probability censoring weights into cluster weighted generalized estimating equations and the other incorporates cluster weights into a multistate model. The methods are applied study the effects of metabolic syndrome on the progression of gum disease using data from the Veterans Affairs Dental Longitudinal Study.

YSPH values inclusion and access for all participants. If you have questions about accessibility or would like to request an accommodation, please contact Charmila Fernandes at Charmila.fernandes@yale.edu. We will try to provide accommodations requested by November 2, 2023.