1990
Molecular cloning and characterization of the immunologically protective surface glycoprotein GP46/M-2 of Leishmania amazonensis.
Lohman K, Langer P, McMahon-Pratt D. Molecular cloning and characterization of the immunologically protective surface glycoprotein GP46/M-2 of Leishmania amazonensis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 8393-8397. PMID: 2236047, PMCID: PMC54962, DOI: 10.1073/pnas.87.21.8393.Peer-Reviewed Original ResearchConceptsGP46/MDNA sequence dataHydrophobic leader peptideCarboxyl-terminal domainMetal-binding motifGlycosyl-phosphatidylinositol anchorAmino-terminal portionProtozoan Leishmania amazonensisSouthern blot analysisGene familyMature proteinPutative attachment siteMolecular cloningProtein comprisesRepetitive sequencesSequence dataCarboxyl terminusCysteine residuesProtein sequencesLeader peptideMembrane locationBinding motifLeishmania amazonensisMembrane glycoproteinsBlot analysisEvolution of nuclear DNA and the occurrence of sequences related to new small chromosomal DNAs in the trypanosomatid genus Endotrypanum
de C.S. Lopes A, Iovannisci D, Petrillo-Peixoto M, McMahon-Pratt D, Beverley S. Evolution of nuclear DNA and the occurrence of sequences related to new small chromosomal DNAs in the trypanosomatid genus Endotrypanum. Molecular And Biochemical Parasitology 1990, 40: 151-161. PMID: 2362601, DOI: 10.1016/0166-6851(90)90037-m.Peer-Reviewed Original ResearchConceptsHybridization probesMolecular karyotype analysisMolecular evolutionary treeComplex hybridization patternDNA restriction fragment patternsRestriction fragment patternsEvolutionary relatednessSequence divergenceDisjunct distributionEvolutionary treeTrypanosomatid parasitesGenus EndotrypanumNuclear DNAChromosomal DNAHybridization patternsRelated sequencesRestriction enzymesChromosomesEndotrypanumFragment patternsKaryotype analysisOccurrence of sequencesDNAGroup B isolatesVirus-like particles
1985
Brazilian Leishmania stocks phenotypically similar to Leishmania major.
Momen H, Pacheco R, Jaffe C, Grimaldi G, Marzochi M, McMahon-Pratt D. Brazilian Leishmania stocks phenotypically similar to Leishmania major. American Journal Of Tropical Medicine And Hygiene 1985, 34: 1076-84. PMID: 3834794, DOI: 10.4269/ajtmh.1985.34.1076.Peer-Reviewed Original ResearchConceptsEnzyme profilesEnzyme electrophoresisL. mexicanaRestriction enzyme profilesL. donovani speciesIndirect radioimmuneNew World LeishmaniaL. braziliensisSchizodeme analysisL. majorMonoclonal antibodiesCutaneous speciesReference strainsSpeciesDifferent geographic areasMexicanaL. donovaniElectrophoresisLeishmaniaLarge panelSubspeciesBspRIMspIBraziliensisGeographic areas