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Vaccines

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Vaccines are one of the greatest achievements of public health in the 20th century. Universal immunization of infants and children, which began in the 1940s, has reduced the burden of previously common and potentially fatal infectious diseases. Despite remarkable progress, challenges remain. Each year, thousands of cases of vaccine preventable diseases still occur. Effective vaccines are still not available for many infectious diseases. Pathogens may evolve in response to vaccination with imperfect vaccines. Complacency toward immunization and anti-vaccination sentiment is growing in the United States and Europe while many vaccine preventable diseases persist in developing countries. Faculty work closely with public health practitioners and policymakers at CDC, WHO, the Bill and Melinda Gates Foundation, and GAVI on these issues.

Research in the Department of the Epidemiology of Microbial Diseases focuses on the following areas:

  • Development and use of novel mathematical and statistical models to predict and evaluate the impact of vaccinations
  • Surveillance to monitor the impact of vaccines
  • Evaluation of attitudes and barriers to vaccination
  • Studies to optimize the effectiveness and cost-effectiveness of vaccination strategies
  • Studies on the impacts of microbial evolution on long-term vaccine effectiveness
  • Fundamental biological research on host immune effectors that will facilitate the development of new vaccines.

Faculty of Interest

  • Associate Professor of Epidemiology (Mircrobial Diseases); Affiliated Faculty, Yale Institute for Global Health

    Research Interests
    • Africa
    • Ecology
    • Genetics
    • Genetics, Population
    • Senegal
    • Malaria, Falciparum
    • Molecular Epidemiology
    • Malaria Vaccines
    • Disease Transmission, Infectious
    • Genomics
    • Host-Pathogen Interactions
    • Adaptive Immunity
    • Biostatistics
  • Burnett and Stender Families Professor of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health; Director of the Center for Infectious Disease Modeling and Analysis (CIDMA)

    Research Interests
    • Acquired Immunodeficiency Syndrome
    • Africa, Southern
    • Ecology
    • Economics
    • Epidemiologic Methods
    • Epidemiology
    • Biological Evolution
    • HIV
    • Influenza, Human
    • Parasitology
    • Public Health
    • Tuberculosis
    • Global Health
    • Evolution, Planetary
    • Infectious Disease Medicine
  • Raj and Indra Nooyi Professor of Public Health and Professor of Epidemiology (Microbial Diseases) and of Medicine (Infectious Diseases); Affiliated Faculty, Yale Institute for Global Health

    Research Interests
    • Dengue
    • Epidemiology
    • Leptospirosis
    • Urban Health
    • Global Health
    • Meningitis, Bacterial
    • Infectious Disease Medicine
  • Associate Dean for Academic Affairs and Professor of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health; Director, HPV Working Group at Yale; Director, CT Emerging Infections Program at Yale, Epidemiology of Microbial Diseases

    Research Interests
    • Epidemiologic Methods
    • Epidemiology
    • HIV
    • Sexually Transmitted Diseases
    • Vaccines
    • Communicable Diseases, Emerging
    • Qualitative Research
    • Human papillomavirus 11
  • Professor Adjunct; Affiliated Faculty, Yale Institute for Global Health

    Research Interests
    • Drug Resistance
    • Pneumonia
    • Respiratory Tract Infections
    • Infection Control
    • Pulmonary Disease, Chronic Obstructive
    • Gastrointestinal Microbiome
  • Associate Professor of Epidemiology (Microbial Diseases); Co-director, Public Health Modeling Concentration; Affiliated Faculty, Yale Institute for Global Health

    Research Interests
    • Ecology
    • Immunization
    • Paratyphoid Fever
    • Rotavirus
    • Typhoid Fever
    • Global Health
  • Associate Professor Tenure; Co-director, Public Health Modeling Concentration; Affiliated Faculty, Yale Institute for Global Health

    Research Interests
    • Americas
    • Bacterial Infections
    • Biology
    • Carrier State
    • Communicable Disease Control
    • Denmark
    • Epidemiologic Methods
    • Europe
    • Fourier Analysis
    • Iceland
    • Influenza, Human
    • Netherlands
    • Population Characteristics
    • Public Health
    • Respiratory Tract Infections
    • Streptococcus pneumoniae
    • Biostatistics
    • Diseases

Secondary & Adjunct Faculty

  • Associate Director, Yale Emerging Infections Program, and Lecturer in Epidemiology (Microbial Diseases); Associate Director, Yale Emerging Infections Program

    Research Interests
    • Epidemiology
    • Tick Control
    • Ticks
    • Zoonoses
  • Professor of Pediatrics (Infectious Diseases) and of Epidemiology (Microbial Diseases); Vice Chair for Research, Department of Pediatrics, Pediatrics; Deputy Director, Investigative Medicine PhD Program, Investigative Medicine Program; Co-Director of Education, Yale Center for Clinical Investigation, YCCI Senior Leadership; Affiliated Faculty, Yale Institute for Global Health

    Research Interests
    • Education
    • Lyme Disease
    • Investigative Techniques
    • Pediatrics
    • Vaccines
    • Case-Control Studies
    • Infectious Disease Medicine
    • Translational Research, Biomedical
  • Epidemiologist 3 and Lecturer in Epidemiology (Microbial Diseases); Program Manager, RESP-NET, Connecticut Emerging Infections Program

    Research Interests
    • Epidemiology
    • Influenza, Human
    • Lyme Disease
    • Population Surveillance
    • Rabies
    • Zoonoses
    • Infectious Disease Medicine