Rena Jones, PhD, MS
Assistant Professor AdjunctCards
About
Research
Publications
2026
Maternal serum concentrations of persistent organic pollutants and childhood acute lymphoblastic leukemia in the Finnish Maternity Cohort
Ward M, Madrigal J, Troisi R, Surcel H, Öhman H, Kivelä J, Kiviranta H, Rantakokko P, Koponen J, Medgyesi D, McGlynn K, Keil A, Albert P, Jones R. Maternal serum concentrations of persistent organic pollutants and childhood acute lymphoblastic leukemia in the Finnish Maternity Cohort. Environmental Research 2026, 124280. PMID: 41833871, DOI: 10.1016/j.envres.2026.124280.Peer-Reviewed Original ResearchPersistent organic pollutantsPolychlorinated biphenylsTrans-nonachlorChildhood leukemia riskOrganic pollutantsFinnish Maternity CohortAcute lymphoblastic leukemiaConcentrations of persistent organic pollutantsAssociated with acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaEffects of persistent organic pollutantsSerum concentrations of persistent organic pollutantsMaternal serum concentrationsLeukemia riskMaternity CohortOdds ratioPopulation-based pregnancy cohortQuantile-based g-computationConfidence intervalsAssociated with childhood acute lymphoblastic leukemiaOrganochlorine pesticidesConditional logistic regressionLymphoblastic leukemiaSampling datesB-hexachlorocyclohexane
2025
Trends in Childhood and Adolescent Cancer Incidence Rates in the United States between 2001 and 2022.
Shiels M, Haque A, Jones R, Kitahara C, Glod J, Widemann B, Morton L, Chanock S, Savage S. Trends in Childhood and Adolescent Cancer Incidence Rates in the United States between 2001 and 2022. Cancer Discovery 2025 PMID: 41370847, DOI: 10.1158/2159-8290.cd-25-1493.Peer-Reviewed Original ResearchCancer incidence ratesChildhood cancer diagnosisIncidence of cancerPutative risk factorsScreening practicesCancer ratesCentral nervous system tumorsLeukemia ratesIncidence rateCancer diagnosisLymphoma ratesNervous system tumorsNational dataRisk factorsEpithelial neoplasmsSystem tumorsStatistical databasesChildhoodCancerUnited StatesDiagnostic technologiesPotential contributionReply to Zhou et al.: Methodological Pitfalls Undermine Industrial Emission-related Lung Cancer Risk Assessment
Madrigal J, Fisher J, Pruitt C, Liao L, Graubard B, Ward M, Silverman D, Jones R. Reply to Zhou et al.: Methodological Pitfalls Undermine Industrial Emission-related Lung Cancer Risk Assessment. American Journal Of Respiratory And Critical Care Medicine 2025, 211: 2420-2421. PMID: 40845341, PMCID: PMC12700262, DOI: 10.1164/rccm.202507-1584le.Peer-Reviewed Original ResearchAmbient air pollution exposure and lung cancer risk in a large prospective U.S. cohort
Fisher J, Liao L, Graubard B, Kaufman J, Silverman D, Jones R. Ambient air pollution exposure and lung cancer risk in a large prospective U.S. cohort. The Science Of The Total Environment 2025, 1002: 180490. PMID: 41027348, PMCID: PMC12716236, DOI: 10.1016/j.scitotenv.2025.180490.Peer-Reviewed Original ResearchLung cancer riskOutdoor PM2.5Smoking statusCancer riskAmbient air pollution exposureU.S. cohortRisk of lung cancerIncident lung cancerNOAssociated with lung cancerAir pollution exposureMedian household incomeOutdoor air pollutionStudy catchment areaRisk of squamous cell carcinomaNIH-AARPPre-enrollment periodHealth StudyEffect modificationIQR increaseCatchment areaPollution exposureHazard ratioHousehold incomeLung cancerAccuracy of LexisNexis-derived retrospective address histories in the Sister Study cohort
Ish J, Daniel M, Ringwald P, Niehoff N, Jones R, White A. Accuracy of LexisNexis-derived retrospective address histories in the Sister Study cohort. Journal Of Exposure Science & Environmental Epidemiology 2025, 1-7. PMID: 40855130, PMCID: PMC12444789, DOI: 10.1038/s41370-025-00802-1.Peer-Reviewed Original ResearchResidential historySister Study participantsSister Study cohortEnvironmental exposuresAddress historiesSister StudyCohort enrollmentStudy participantsSupplemental questionnaireProspective cohortReinforcing confidenceEpidemiological studiesStudy cohortAddress dataHealth effectsParticipantsCohortAccurate assessmentResidence durationLexisNexisGeographical characteristicsYears of dataHealthQuestionnaireTimeframeSerum concentrations of perfluoroalkyl and polyfluoroalkyl substances and risk of ovarian cancer
Jones R, Madrigal J, Medgyesi D, Fisher J, Calafat A, Botelho J, Kato K, Albert P, Silverman D, Hofmann J, Trabert B. Serum concentrations of perfluoroalkyl and polyfluoroalkyl substances and risk of ovarian cancer. Journal Of The National Cancer Institute 2025, 117: 2272-2279. PMID: 40748719, PMCID: PMC12597518, DOI: 10.1093/jnci/djaf204.Peer-Reviewed Original ResearchOvarian cancerQuartile trendOvarian cancer risk factorsOvarian Cancer Screening TrialFamily historyFamily history of cancerRisk of ovarian cancerSerum concentrationsCancer risk factorsCancer Screening TrialHistory of cancerNested Case-Control StudyOvarian cancer casesOral contraceptive useMenopausal hormone therapyPrediagnostic serum samplesBody mass indexCase-control studyLogistic regression modelsHormone therapyScreening TrialCancer casesHighest quartilesFatal malignancyGynecologic cancerCarcinogenic Industrial Air Emissions and Lung Cancer Risk in a Cohort of 440,000 Americans.
Madrigal J, Fisher J, Pruitt C, Liao L, Graubard B, Ward M, Silverman D, Jones R. Carcinogenic Industrial Air Emissions and Lung Cancer Risk in a Cohort of 440,000 Americans. American Journal Of Respiratory And Critical Care Medicine 2025, 211: 1241-1252. PMID: 40315142, PMCID: PMC12264657, DOI: 10.1164/rccm.202409-1738oc.Peer-Reviewed Original ResearchConceptsLung cancer riskCancer riskAssociated with riskNIH-AARP DietEvaluate lung cancer riskLung carcinogensAssociated with lung cancerCox proportional hazards modelsNIH-AARPHealth StudyProportional hazards modelSquamous cell carcinomaStrong associationsAssociated with benzeneHazards modelIndustrial air emissionsEnrollment residenceCell carcinomaOverall riskLung cancer developmentSmokingAssociationRiskHistological subtypesLung cancerCommunity Water Trihalomethanes and Chronic Kidney Disease
Medgyesi D, Mohan S, Bangia K, Spielfogel E, Spaur M, Fisher J, Madrigal J, Navas-Acien A, Freeman L, Jones R, Ward M, Lacey J, Sanchez T. Community Water Trihalomethanes and Chronic Kidney Disease. JAMA Network Open 2025, 8: e2518513. PMID: 40601319, PMCID: PMC12223891, DOI: 10.1001/jamanetworkopen.2025.18513.Peer-Reviewed Original ResearchConceptsCalifornia Teachers StudyChronic kidney disease riskProspective cohort studyParticipants' homesHazard ratioMultivariable-adjusted Cox proportional hazards regression modelsDiagnostic codesLong-term exposure to trihalomethanesProspective cohortBurden of chronic kidney diseaseHealth care recordsChronic kidney diseaseAdverse birth outcomesExposure-response associationsCox proportional hazards regression modelsProportional hazards regression modelsChronic kidney disease casesPublic health implicationsHazards regression modelsCare recordsBirth outcomesAssociated with chronic kidney diseaseMain OutcomesEpidemiological researchUS populationAmbient dioxin exposure and incidence of lymphoid malignancies in large prospective US cohorts of female nurses
Chen J, Hart J, VoPham T, Elliott E, Jones R, Ward M, Laden F, Birmann B. Ambient dioxin exposure and incidence of lymphoid malignancies in large prospective US cohorts of female nurses. Journal Of Hazardous Materials 2025, 495: 139115. PMID: 40609469, PMCID: PMC12305743, DOI: 10.1016/j.jhazmat.2025.139115.Peer-Reviewed Original ResearchConceptsDuration of residenceCohort of female nursesResidential proximityUS cohortNon-Hodgkin's lymphomaHazard ratioTime-varying Cox proportional hazards modelsNurses' Health StudyAssociated with residential proximityCohort-specific resultsConfidence intervalsNon-Hodgkin lymphoma subtypesPositive associationIncident non-Hodgkin's lymphomaCox proportional hazards modelsDioxin exposureFemale nursesMultiple myelomaHealth StudyProportional hazards modelNationwide cohortProspective cohortOverall NHLMM casesMM incidencePrediagnostic Serum Concentrations of Per- and Polyfluoroalkyl Substances and Risk of Endometrial Cancer in a US Cohort
Madrigal J, Trabert B, Medgyesi D, Fisher J, Calafat A, Botelho J, Kato K, Albert P, Silverman D, Hofmann J, Jones R. Prediagnostic Serum Concentrations of Per- and Polyfluoroalkyl Substances and Risk of Endometrial Cancer in a US Cohort. Environmental Health Perspectives 2025, 133: 067701. PMID: 40262115, PMCID: PMC12142652, DOI: 10.1289/ehp16569.Peer-Reviewed Original Research
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