Nicole Deziel, PhD, MHS
Associate Professor of Epidemiology (Environmental Health Sciences)Cards
Additional Titles
Co-Director, Yale Center for Perinatal, Pediatric and Environmental Epidemiology (CPPEE)
Contact Info
Environmental Health Sciences
60 College St.
New Haven, CT 06510
United States
About
Titles
Associate Professor of Epidemiology (Environmental Health Sciences)
Co-Director, Yale Center for Perinatal, Pediatric and Environmental Epidemiology (CPPEE)
Biography
Dr. Deziel obtained a Master’s of Industrial Hygiene and Doctorate in Environmental Health from the Johns Hopkins Bloomberg School of Public Health. Her research is focused on applying statistical models, biomonitoring techniques, and environmental measurements to provide comprehensive and quantitative assessments of exposure to traditional and emerging environmental contaminants in population-based studies. Her research uses a combination of large, administrative datasets and detailed community-focused studies to advance understanding of environmental exposures to chemicals, particularly carcinogens and endocrine disruptors. This research also serves to illuminate exposure mechanisms underlying associations between environmental chemicals and disease, thereby informing more effective policies to reduce exposures and protect public health. Dr. Deziel's contributions have been directed at two main areas: (1) exposure and human health impacts of unconventional oil and gas development (“hydraulic fracturing”) and (2) residential exposure to chemicals in common consumer products (e.g., pesticides, flame retardants) and cancer risk (particularly thyroid cancer). In addition, she consider disproportionate burdens of exposures (“environmental justice”) and the combination of environmental and social stressors in the context of her work.
Appointments
Environmental Health Sciences
Associate Professor TenurePrimaryChemical and Environmental Engineering
Associate Professor TenureSecondarySchool of the Environment
Associate Professor on TermSecondary
Other Departments & Organizations
- Cancer Prevention and Control
- Center for Perinatal, Pediatric and Environmental Epidemiology (CPPEE)
- Chemical and Environmental Engineering
- Climate Change and Health
- Deziel Lab
- Environmental Health Sciences
- Environmental Health Sciences (EHS)
- GEOHealth-MENA program
- School of the Environment
- The WATER Study: WATer and Energy Resources Study
- Yale Cancer Center
- Yale School of Public Health
- Yale School of Public Health - NEW
- Yale Superfund Research Center
Education & Training
- PhD
- Johns Hopkins Bloomberg School of Public Health (2008)
- MHS
- Johns Hopkins Bloomberg School of Public Health (2000)
Research
Overview
Public Health Interests
ORCID
0000-0002-5751-9191- View Lab Website
Deziel Exposure Science Lab
Research at a Glance
Yale Co-Authors
Publications Timeline
Xiaomei Ma, PhD
Joshua Warren, PhD
Caroline Helen Johnson, PhD
Michelle L. Bell, PhD
James Saiers, PhD
Krystal Pollitt, PhD, P.Eng.
Publications
2024
Effects of ambient temperature on mental and neurological conditions in older adults: A systematic review and meta-analysis
Byun G, Choi Y, Foo D, Stewart R, Song Y, Son J, Heo S, Ning X, Clark C, Kim H, Michelle Choi H, Kim S, Kim S, Burrows K, Lee J, Deziel N, Bell M. Effects of ambient temperature on mental and neurological conditions in older adults: A systematic review and meta-analysis. Environment International 2024, 194: 109166. PMID: 39603080, DOI: 10.1016/j.envint.2024.109166.Peer-Reviewed Original ResearchConceptsOlder adultsWorld Health OrganizationHealth of older adultsStudy designNeurological conditionsSystematic reviewMental disordersRisk ratioEpidemiological evidenceAmbient temperature exposureCase-crossover analysisRandom-effects meta-analysesExposure metricsOlder adult populationIncreased riskMeta-analysisPooled effect estimatesRisk of biasCertainty of evidencePeer-reviewed journal articlesPooled risk ratioWeb of ScienceHealth outcomesScreened articlesModerate certaintyDomestic groundwater wells in Appalachia show evidence of low-dose, complex mixtures of legacy pollutants
Bugher N, Xiong B, Gentles R, Glist L, Siegel H, Johnson N, Clark C, Deziel N, Saiers J, Plata D. Domestic groundwater wells in Appalachia show evidence of low-dose, complex mixtures of legacy pollutants. Environmental Science Processes & Impacts 2024 PMID: 39501836, DOI: 10.1039/d4em00364k.Peer-Reviewed Original ResearchConceptsVolatile organic compoundsMaximum contaminant levelEnvironmental Protection AgencyDrinking water sourcesContaminated sitesVOC concentrationsIndustrial activitiesConcentrations of volatile organic compoundsVolatile organic compound contaminationVolatile organic compound concentrationsWater sourcesIndustrially contaminated sitesLack of water quality dataPotential groundwater contaminationU.S. Environmental Protection AgencyWater quality dataComplex geochemical processesLegacy pollutantsGroundwater contaminationSuperfund siteContaminant occurrenceWest VirginiaMultiple volatile organic compoundsContamination levelsExposure riskQuantitative measures of recent and lifetime agricultural pesticide use are associated with increased pesticide concentrations in house dust
Xie S, Hofmann J, Sampson J, Josse P, Madrigal J, Chang V, Deziel N, Andreotti G, Keil A, Ward M, Beane Freeman L, Friesen M. Quantitative measures of recent and lifetime agricultural pesticide use are associated with increased pesticide concentrations in house dust. Environment International 2024, 193: 109123. PMID: 39541787, DOI: 10.1016/j.envint.2024.109123.Peer-Reviewed Original ResearchConceptsAgricultural pesticide usePesticide concentrationsAgricultural usePesticide useBanned pesticidesDust samplesElevated pesticide concentrationsBiomarkers of exposure and effectExposure and effectConcentrations of malathionVacuum dust samplesEvaluate temporal variabilityDust concentrationHeptachlor concentrationsP′-DDDP-DDEDieldrin concentrationsCyfluthrin concentrationsAgricultural pesticidesPesticidesPesticide analytesTemporal variabilityEstimate relative differencesIntraclass correlation coefficientHouse dustUsing a Bayesian analytic approach to identify county-level ecological factors associated with survival among individuals with early-onset colorectal cancer
Siddique S, Baum L, Deziel N, Kelly J, Warren J, Ma X. Using a Bayesian analytic approach to identify county-level ecological factors associated with survival among individuals with early-onset colorectal cancer. PLOS ONE 2024, 19: e0311540. PMID: 39471191, PMCID: PMC11521299, DOI: 10.1371/journal.pone.0311540.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsAge-of-onset colorectal cancerEarly-onset colorectal cancerEnd Results Program dataCenters for Disease Control and Prevention dataCounty-level factorsColorectal cancerHealth risk behaviorsIdentified principal componentsOdds of survivalPreventive servicesSurvival disparitiesLinear mixed modelsEOCRCChronic diseasesPreventive factorsUS countiesSalt Lake CountyCA residentsRisk behaviorsUnited StatesProgram dataCounty-levelOlder ageBayesian analytical approachYounger ageDelineating Urbanicity and Rurality: Impact on Environmental Exposure Assessment
Song Y, Deziel N, Bell M. Delineating Urbanicity and Rurality: Impact on Environmental Exposure Assessment. Environmental Science And Technology 2024, 58: 19178-19188. PMID: 39412270, DOI: 10.1021/acs.est.4c06942.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsEnvironmental exposuresEnvironmental exposure assessmentExposure of particulate matterUrban/rural disparitiesDemographic compositionHealth StudyHealth researchPopulation-basedClassification systemExposure assessmentSpatial patternsHealth impactsRural areasHealthRuralParticulate matterLand surface temperatureWest VirginiaUnited StatesSurface temperatureUrbanizationResearch questionsAssessmentDisparitiesExposureExposure range matters: considering non-linear associations in the meta-analysis of environmental pollutant exposure using examples of per- and polyfluoroalkyl substances and birth outcomes
Guo P, Warren J, Deziel N, Liew Z. Exposure range matters: considering non-linear associations in the meta-analysis of environmental pollutant exposure using examples of per- and polyfluoroalkyl substances and birth outcomes. American Journal Of Epidemiology 2024, kwae309. PMID: 39227151, DOI: 10.1093/aje/kwae309.Peer-Reviewed Original ResearchConceptsNon-linear associationMeta-analysisHeterogeneity of effect estimatesEffect estimatesPotential non-linear associationsExposure-outcome relationshipsRisk of preterm birthSubgroup meta-analysisBirth outcomesPollution exposureMeta-analytic approachMeta-analysesEffect sizeEnvironmental pollutant exposureResults heterogeneityExposure levelsHealth effectsPreterm birthEvidence-based policymakingPrenatal exposurePotential heterogeneityMean birth weightBirth weightMethodological challengesCut-off choiceQuantitative measures of recent and lifetime agricultural pesticide use are associated with increased pesticide concentrations in house dust
Xie S, Hofmann J, Sampson J, Josse P, Madrigal J, Chang V, Deziel N, Andreotti G, Keil A, Ward M, Beane Freeman L, Friesen M. Quantitative measures of recent and lifetime agricultural pesticide use are associated with increased pesticide concentrations in house dust. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0458.Peer-Reviewed Original ResearchExposures to Artificial Light at Night and Ambient Fine Particulate Matter and Risk of Pediatric Papillary Thyroid Cancer
Deziel N, Wang R, Warren J, Dinauer C, Ogilvie J, Clark C, Zhong C, Wiemels J, Morimoto L, Metayer C, Ma X. Exposures to Artificial Light at Night and Ambient Fine Particulate Matter and Risk of Pediatric Papillary Thyroid Cancer. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0720.Peer-Reviewed Original ResearchCitationsExposure to ambient air pollution during early life and risk of childhood Ewing sarcoma in a California case-control study (1988-2015)
Clark C, Wang R, Deziel N, Wiemels J, Metayer C, Ma X. Exposure to ambient air pollution during early life and risk of childhood Ewing sarcoma in a California case-control study (1988-2015). ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0493.Peer-Reviewed Original ResearchProximity of public K-12 schools to oil and gas development in the U.S.: Implications for environmental justice and children’s health
Clark C, Campbell E, Mooney F, Buonocore J, Casey J, Deziel N, Willis M. Proximity of public K-12 schools to oil and gas development in the U.S.: Implications for environmental justice and children’s health. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0488.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
honor Yale Cancer Center Population Science Research Prize
Yale School of Medicine AwardDetails12/01/2020United Stateshonor Joan M. Daisey Outstanding Young Exposure Scientist Award
International AwardInternational Society of Exposure ScienceDetails12/31/2018United States
News & Links
News
- November 22, 2024Source: Yale Daily News
How the lack of water fluoridation could impact communities across the US
- November 19, 2024
Yale environmental health expert discusses concerns about fracking
- November 11, 2024Source: BBC
'Dying of thirst' as climate-driven floods mix with oil
- September 18, 2024Source: Arlington Report
After two rejections, proposal to expand natural gas drilling near Arlington day care returns
Get In Touch
Contacts
Environmental Health Sciences
60 College St.
New Haven, CT 06510
United States
Locations
60 College Street
Academic Office
New Haven, CT 06510