- January 04, 2025Source: Hartford Courant
CT cancer expert on U.S. surgeon general on alcohol and cancer risk: ‘Cutting back makes sense’
- December 10, 2024
New Database Documents Sex Differences in Cancer Biology, Risk Factors, and Treatments
- November 19, 2024
Yale environmental health expert discusses concerns about fracking
- November 08, 2024
Liver Cancer Screening: A New Tool for Improved Detection
Cancer
More people today die from cancer than from almost any other cause in the world. The challenges posed by cancer are immense and top scientists at the Yale School of Public Health are committed to reducing its toll.
The departments of Chronic Disease Epidemiology, Biostatistics and Health Policy and Management are heavily focused on a wide variety of cancer-related research, and the Department of Environmental Health Sciences is renowned for novel approaches to the study of how environmental exposures affect health outcomes. From key partnerships with the Yale Cancer Center to collaborative efforts locally and globally, YSPH scientists are taking significant steps toward preventing and treating a wide range of cancers. Today, research in cancer and other chronic diseases encompasses interdisciplinary teams committed to understanding cancer causation and etiology, prevention, screening and early detection, risk factors, environmental exposures, social determinants of health and survival.
A variety of technologies and approaches are used to detect mechanisms and characteristics of the many different types of cancer, including genomics, metabolomics, social and behavioral effects, evolutionary biology, biostatistical methodology and study design, and outcomes research.
The Yale School of Public Health maintains biospecimens and data from thousands of individuals in more than a dozen studies that can be made applied to future research. It also has partnerships with numerous international cancer researchers, and is the home of leading experts in clinical trial design and data management, and genomic and metabolic centers.
Recent Publications
- Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions.Jia G, Chen Z, Ping J, Cai Q, Tao R, Li C, Bauer JA, Xie Y, Ambs S, Barnard ME, Chen Y, Choi JY, Gao YT, Garcia-Closas M, Gu J, Hu JJ, Iwasaki M, John EM, Kweon SS, Li CI, Matsuda K, Matsuo K, Nathanson KL, Nemesure B, Olopade OI, Pal T, Park SK, Park B, Press MF, Sanderson M, Sandler DP, Shen CY, Troester MA, Yao S, Zheng Y, Ahearn T, Brewster AM, Falusi A, Hennis AJM, Ito H, Kubo M, Lee ES, Makumbi T, Ndom P, Noh DY, O'Brien KM, Ojengbede O, Olshan AF, Park MH, Reid S, Yamaji T, Zirpoli G, Butler EN, Huang M, Low SK, Obafunwa J, Weinberg CR, Zhang H, Zhao H, Cote ML, Ambrosone CB, Huo D, Li B, Kang D, Palmer JR, Shu XO, Haiman CA, Guo X, Long J, Zheng W. Nat Genet. 2025 Jan 3; 2025 Jan 3. PMID: 39753771.
- [Retracted] MicroRNA‑34a expression affects breast cancer invasion in vitro and patient survival via downregulation of E2F1 and E2F3 expression.Han R, Zhao J, Lu L. Oncol Rep. 2025 Jan; 2024 Nov 14. PMID: 39540400.
- Tertiary Lymphoid Structures and Immunotherapy: Challenges and Opportunities.Ruddle NH. Methods Mol Biol. 2025. PMID: 39527229.
- Living Flat: Stories from Women of Color After Mastectomy.Khubchandani JA, Suttiratana SC, Washington R, White-Bracey D, Kc M, Silber A, Fayanju OM, Butler PD, Menon A, Greenup RA. Ann Surg Oncol. 2025 Jan; 2024 Oct 15. PMID: 39407064.
- Varying the intensity of cystoscopic surveillance for high-risk non-muscle-invasive bladder cancer.Su ZT, Florissi IS, Mahon KM, Li T, Rezaee ME, Singla N, Patel SH, Townsend JP, Kates MR. BJU Int. 2025 Jan; 2024 Aug 29. PMID: 39210627.
- Asparagine synthetase and G-protein coupled estrogen receptor are critical responders to nutrient supply in KRAS mutant colorectal cancer.Lu L, Zhang Q, Aladelokun O, Berardi D, Shen X, Marin A, Garcia-Milian R, Roper J, Khan SA, Johnson CH. Int J Cancer. 2025 Jan 1; 2024 Jul 22. PMID: 39039782.
- Prostate-specific antigen screening for prostate cancer: Diagnostic performance, clinical thresholds, and strategies for refinement.Sundaresan VM, Smani S, Rajwa P, Renzulli J, Sprenkle PC, Kim IY, Leapman MS. Urol Oncol. 2025 Jan; 2024 Jul 17. PMID: 39019723.
- Risks of grade reclassification among patients with Gleason grade group 1 prostate cancer and PI-RADS 5 findings on prostate MRI.Sundaresan VM, Webb L, Rabil M, Golos A, Sutherland R, Bailey J, Rajwa P, Seibert TM, Loeb S, Cooperberg MR, Catalona WJ, Sprenkle PC, Kim IY, Leapman MS. Urol Oncol. 2024 Dec 19; 2024 Dec 19. PMID: 39706698.
- Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020.Ajjawi I, Loeb S, Cooperberg MR, Catalona WJ, Gross CP, Ma X, Leapman MS. JAMA. 2024 Dec 17. PMID: 39565605.
- Socio-economic factors associated with cancer stigma among apparently healthy women in two selected municipalities Nepal.Paneru B, Karmacharya A, Makaju S, Kafle D, Poudel L, Mali S, Timsina P, Shrestha N, Timalsena D, Chaudhary K, Bhandari N, Rai P, Shakya S, Spiegelman D, Sheth SS, Stangl A, Eastment MC, Shrestha A. PLoS One. 2024; 2024 Dec 16. PMID: 39680514.
- US Tobacco 21 Policies and Potential Mortality Reductions by State.Tam J, Crippen A, Friedman A, Jeon J, Colston DC, Fleischer NL, Vander Woude CA, Boelter MA, Holford TR, Levy DT, Meza R. JAMA Health Forum. 2024 Dec 6; 2024 Dec 6. PMID: 39705045.
- Estimation of Cancer Deaths Averted From Prevention, Screening, and Treatment Efforts, 1975-2020.Goddard KAB, Feuer EJ, Mandelblatt JS, Meza R, Holford TR, Jeon J, Lansdorp-Vogelaar I, Gulati R, Stout NK, Howlader N, Knudsen AB, Miller D, Caswell-Jin JL, Schechter CB, Etzioni R, Trentham-Dietz A, Kurian AW, Plevritis SK, Hampton JM, Stein S, Sun LP, Umar A, Castle PE. JAMA Oncol. 2024 Dec 5; 2024 Dec 5. PMID: 39636625.
- 16S rRNA target sequencing of human tumors validates findings of Lachnoclostridium abundance in human melanomas that are heavily CD8+ T-cell infiltrated.Lu L, Johnson C, Khan S, Kluger H. Eur J Cancer. 2024 Dec; 2024 Oct 24. PMID: 39477777.
- Diagnostic experiences of Black and White patients with uterine cancer: A qualitative study.Britton MC, Izampuye E, Clark M, Ornstein RA, Nunez-Smith M, Wright JD, Xu X. Gynecol Oncol. 2024 Dec; 2024 Oct 2. PMID: 39362045.
- A gap analysis of UK biobank publications reveals SNPs associated with intrinsic subtypes of breast cancer.van den Driest L, Kelly P, Marshall A, Johnson CH, Lasky-Su J, Lannigan A, Rattray Z, Rattray NJW. Comput Struct Biotechnol J. 2024 Dec; 2024 May 10. PMID: 38817965.
- The Incidence and Significance of Iliac Vein Stenosis in Patients with Deep Vein Thrombosis.Ali S, Chan SM, Brahmandam A, Xu Y, Deng Y, Elbadawy A, Lee A, Ochoa Chaar CI. Ann Vasc Surg. 2024 Nov 29; 2024 Nov 29. PMID: 39617297.
- Canonical Amplifications and CDKN2A/B Loss Refine IDH1/2-mutant Astrocytoma Prognosis.Ghosh HS, Patel RV, Claus EB, Gonzalez Castro LN, Wen PY, Ligon KL, Meredith DM, Bi WL. Neuro Oncol. 2024 Nov 25; 2024 Nov 25. PMID: 39584448.
- Per- and polyfluoroalkyl substances (PFAS) and cancer: Detection methodologies, epidemiological insights, potential carcinogenic mechanisms, and future perspectives.Zheng J, Liu S, Yang J, Zheng S, Sun B. Sci Total Environ. 2024 Nov 25; 2024 Sep 8. PMID: 39255941.
- The critical need for a robust research agenda on ultra-processed food consumption and cancer risk.Loftfield E, Moore SC, Mayne ST. PLoS Med. 2024 Nov; 2024 Nov 19. PMID: 39561210.
- Correction: Randomized trial of physical activity on quality of life and lung cancer biomarkers in patients with advanced stage lung cancer: a pilot study.Bade BC, Gan G, Li F, Lu L, Tanoue L, Silvestri GA, Irwin ML. BMC Cancer. 2024 Nov 15; 2024 Nov 15. PMID: 39548453.
- OncoSexome: the landscape of sex-based differences in oncologic diseases.Shen X, Zhang Y, Li J, Zhou Y, Butensky SD, Zhang Y, Cai Z, DeWan AT, Khan SA, Yan H, Johnson CH, Zhu F. Nucleic Acids Res. 2024 Nov 13; 2024 Nov 13. PMID: 39535034.
- Baseline predictors associated with successful weight loss among breast cancer survivors in the Lifestyle, Exercise, and Nutrition (LEAN) study.Hoobler R, Puklin LS, Harrigan M, Cartmel B, Li FY, Sanft T, Ferrucci LM, Irwin ML, Playdon MC. J Cancer Surviv. 2024 Nov 11; 2024 Nov 11. PMID: 39528779.
- Real-world analysis of two ischaemic stroke and TIA systolic blood pressure goals on 12-month mortality and recurrent vascular events.Sico JJ, Hu X, Myers LJ, Levine D, Bravata DM, Arling GW. Stroke Vasc Neurol. 2024 Nov 5; 2024 Nov 5. PMID: 38191185.
- Risk Score for Hepatocellular Cancer in Adults Without Viral Hepatitis or Cirrhosis.Ilagan-Ying YC, Gordon KS, Tate JP, Lim JK, Torgersen J, Lo Re V 3rd, Justice AC, Taddei TH. JAMA Netw Open. 2024 Nov 4; 2024 Nov 4. PMID: 39504020.
- Disparities in Colorectal Cancer Screening Before and After the Onset of the COVID Pandemic.Siddique S, Wang R, Gaddy JJ, Stempel JM, Warren JL, Gross CP, Ma X. J Gen Intern Med. 2024 Nov 4; 2024 Nov 4. PMID: 39495455.
- Accessing breast cancer care in a protracted conflict: Qualitative exploration of the perspectives of women with breast cancer in northwest Syria.Marzouk M, Hamze M, Debel J, Alshemali A, Alameen BA, Bakkour M, Galal B, Chagpar AB, Atassi B, Khoshnood K, Abbara A. Soc Sci Med. 2024 Nov; 2024 Sep 21. PMID: 39357306.
- Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine.Machavariani E, Dumchev K, Pykalo I, Filippovych M, Ivasiy R, Esserman D, Madden LM, Bromberg DJ, Haddad M, Morozova O, Ahmad B, Gómez DO, Farnum SO, Dvoriak S, Altice FL. Contemp Clin Trials. 2024 Nov; 2024 Sep 14. PMID: 39265780.
- Associations Between Prostate Magnetic Resonance Imaging, Genomic Testing, and Treatment for Localized Prostate Cancer.Sundaresan VM, Wang R, Long JB, Sprenkle PC, Seibert TM, Loeb S, Cooperberg MR, Catalona WJ, Ma X, Gross CP, Leapman MS. Urol Pract. 2024 Nov; 2024 Jul 16. PMID: 39196719.
- Predictors of early life residential mobility in urban and rural Pennsylvania children with acute lymphoblastic leukemia and implications for environmental exposure assessment.Clark CJ, Warren JL, Saiers JE, Ma X, Bell ML, Deziel NC. J Expo Sci Environ Epidemiol. 2024 Nov; 2023 Dec 26. PMID: 38148338.
- Using a Bayesian analytic approach to identify county-level ecological factors associated with survival among individuals with early-onset colorectal cancer.Siddique S, Baum LVM, Deziel NC, Kelly JR, Warren JL, Ma X. PLoS One. 2024; 2024 Oct 29. PMID: 39471191.
- Updated CP*Trends: An Online Tool to Compare Cohort and Period Trends across Cancer Sites.Holford TR, Chen HS, Kane MJ, Krapcho M, Annett D, Esclamado L, Melkonyan A, Feuer EJ. Am J Epidemiol. 2024 Oct 28; 2024 Oct 28. PMID: 39475089.
- The protective effect of dietary folate intake on gastric cancer is modified by alcohol consumption: A pooled analysis of the StoP Consortium.Gonzalez-Palacios S, Compañ-Gabucio LM, Torres-Collado L, Oncina-Canovas A, García-de-la-Hera M, Collatuzzo G, Negri E, Pelucchi C, Rota M, López-Carrillo L, Lunet N, Morais S, Ward MH, Martin V, Lozano-Lorca M, Malekzadeh R, Pakseresht M, Hernández-Ramírez RU, Bonzi R, Patel L, López-Cervantes M, Rabkin CS, Tsugane S, Hidaka A, Trichopoulou A, Karakatsani A, Camargo MC, Curado MP, Zhang ZF, La Vecchia C, Boffetta P, Vioque J. Int J Cancer. 2024 Oct 15; 2024 May 16. PMID: 38757245.
- Catabolism of extracellular glutathione supplies amino acids to support tumor growth.Hecht F, Zocchi M, Tuttle ET, Ward NP, Smith B, Kang YP, Cazarin J, Soares ZG, Ozgurses ME, Zhao H, Sheehan C, Alimohammadi F, Munger LD, Trivedi D, Asantewaa G, Blick-Nitko SK, Zoeller JJ, Chen Y, Vasiliou V, Turner BM, Muir A, Coloff JL, Munger J, DeNicola GM, Harris IS. bioRxiv. 2024 Oct 13; 2024 Oct 13. PMID: 39416022.
- Thyroid Cancer Incidence During 2020 to 2021 COVID-19 Variant Waves.Bell R, Weinberger DM, Venkatesh M, Fernandes-Taylor S, Francis DO, Davies L. JAMA Otolaryngol Head Neck Surg. 2024 Oct 10; 2024 Oct 10. PMID: 39388144.
- Long-Term Outcomes of Prostate-Specific Membrane Antigen-PET Imaging of Recurrent Prostate Cancer.Kunst N, Long JB, Westvold S, Sprenkle PC, Kim IY, Saperstein L, Rabil M, Ghaffar U, Karnes RJ, Ma X, Gross CP, Wang SY, Leapman MS. JAMA Netw Open. 2024 Oct 1; 2024 Oct 1. PMID: 39441595.
- Clinician Staffing and Quality of Care in US Health Centers.Sun QW, Forman HP, Stern L, Oldfield BJ. JAMA Netw Open. 2024 Oct 1; 2024 Oct 1. PMID: 39436649.
- USPSTF Colorectal Cancer Screening Recommendation and Uptake for Individuals Aged 45 to 49 Years.Siddique S, Wang R, Yasin F, Gaddy JJ, Zhang L, Gross CP, Ma X. JAMA Netw Open. 2024 Oct 1; 2024 Oct 1. PMID: 39361285.
- Patterns of Physical Therapy Referral and Subsequent Attendance Among Childhood Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy at a Regional Childhood Cancer Survivorship Clinic.Kang L, Kadan-Lottick NS, Rotatori J, Kujawski SE, Messerschmidt E, Auerbach C, Balsamo LM, Lustberg MB, Ma X, Rodwin RL. Semin Oncol Nurs. 2024 Oct; 2024 Aug 19. PMID: 39164160.
- Characterization of time toxicity in older patients with metastatic breast cancer.Atre SY, Soulos PR, Kuderer NM, Gross CP, Baum LVM, Dinan MA, Lustberg MB. Breast Cancer Res Treat. 2024 Oct; 2024 May 31. PMID: 38816556.
- Charting the metabolic biogeography of the colorectum in cancer: challenging the right sided versus left sided classification.Jain A, Morris MT, Berardi D, Arora T, Domingo-Almenara X, Paty PB, Rattray NJW, Kerekes D, Lu L, Khan SA, Johnson CH. Mol Cancer. 2024 Sep 28; 2024 Sep 28. PMID: 39342363.
- Strength of Evidence Underlying the CMS-FDA Parallel Review of Comprehensive Genomic Profiling Tests in the Cancer Setting.Stackland S, Schnabel D, Dinan M, Presley CJ, Gross CP. J Natl Cancer Inst. 2024 Sep 18; 2024 Sep 18. PMID: 39288939.
- The impact of chiropractic care on prescription opioid use for non-cancer spine pain: protocol for a systematic review and meta-analysis.Emary PC, Corcoran KL, Coleman BC, Brown AL, Ciraco C, DiDonato J, Wang L, Couban RJ, Sud A, Busse JW. Syst Rev. 2024 Sep 12; 2024 Sep 12. PMID: 39267131.
- Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery.Liu M, Jin S, Agabiti SS, Jensen TB, Yang T, Radda JSD, Ruiz CF, Baldissera G, Rajaei M, Townsend JP, Muzumdar MD, Wang S. bioRxiv. 2024 Sep 9; 2024 Sep 9. PMID: 37546882.
- Understanding risk factors for endometrial cancer in young women.Peeri NC, Bertrand KA, Na R, De Vivo I, Setiawan VW, Seshan VE, Alemany L, Chen Y, Clarke MA, Clendenen T, Cook LS, Costas L, Dal Maso L, Freudenheim JL, Friedenreich CM, Gierach GL, Goodman MT, La Vecchia C, Levi F, Lopez-Querol M, Lu L, Moysich KB, Mutter G, Naduparambil J, Negri E, O'Connell K, O'Mara T, Palmer JR, Parazzini F, Penney KL, Petruzella S, Reynolds P, Ricceri F, Risch H, Rohan TE, Sacerdote C, Sandin S, Shu XO, Stolzenberg-Solomon RZ, Webb PM, Wentzensen N, Wilkens LR, Xu W, Yu H, Zeleniuch-Jacquotte A, Zheng W, Guo X, Lipworth L, Du M. J Natl Cancer Inst. 2024 Sep 5; 2024 Sep 5. PMID: 39235934.
- Folate Metabolism and Risk of Childhood Acute Lymphoblastic Leukemia: A Genetic Pathway Analysis from the Childhood Cancer and Leukemia International Consortium.Metayer C, Spector LG, Scheurer ME, Jeon S, Scott RJ, Takagi M, Clavel J, Manabe A, Ma X, Hailu EM, Lupo PJ, Urayama KY, Bonaventure A, Kato M, Meirhaeghe A, Chiang CWK, Morimoto LM, Wiemels JL. Cancer Epidemiol Biomarkers Prev. 2024 Sep 3. PMID: 38904462.
- Genome-Wide Analysis to Assess if Heavy Alcohol Consumption Modifies the Association between SNPs and Pancreatic Cancer Risk.Ni Z, Kundu P, McKean DF, Wheeler W, Albanes D, Andreotti G, Antwi SO, Arslan AA, Bamlet WR, Beane-Freeman LE, Berndt SI, Bracci PM, Brennan P, Buring JE, Chanock SJ, Gallinger S, Gaziano JM, Giles GG, Giovannucci EL, Goggins MG, Goodman PJ, Haiman CA, Hassan MM, Holly EA, Hung RJ, Katzke V, Kooperberg C, Kraft P, LeMarchand L, Li D, McCullough ML, Milne RL, Moore SC, Neale RE, Oberg AL, Patel AV, Peters U, Rabe KG, Risch HA, Shu XO, Smith-Byrne K, Visvanathan K, Wactawski-Wende J, White E, Wolpin BM, Yu H, Zeleniuch-Jacquotte A, Zheng W, Zhong J, Amundadottir LT, Stolzenberg-Solomon RZ, Klein AP. Cancer Epidemiol Biomarkers Prev. 2024 Sep 3. PMID: 38869494.
- Telomere transcripts act as tumor suppressor and are associated with favorable prognosis in colorectal cancer with low proliferating cell nuclear antigen expression.Kienzl P, Deloria AJ, Hunjadi M, Hadolt JM, Haering MF, Bothien A, Mejri D, Korkut-Demirbaş M, Sampl S, Weber G, Pirker C, Laengle S, Braunschmid T, Dragona E, Marian B, Gagos S, Lu L, Henson JD, Lau LMS, Reddel RR, Mikulits W, Stättner S, Holzmann K. Cell Oncol (Dordr). 2024 Sep 2; 2024 Sep 2. PMID: 39222177.
- Artificial Intelligence-Enhanced Risk Stratification of Cancer Therapeutics-Related Cardiac Dysfunction Using Electrocardiographic Images.Oikonomou EK, Sangha V, Dhingra LS, Aminorroaya A, Coppi A, Krumholz HM, Baldassarre LA, Khera R. Circ Cardiovasc Qual Outcomes. 2024 Sep 2; 2024 Sep 2. PMID: 39221857.
- A Brief Report of Lung Cancer Screening Utilization Before, During, and in the Later Stages of the COVID-19 Pandemic in the United States.Poghosyan H, Sarkar S, Richman I, Pietrzak RH, Carter-Bawa L, Cooley ME. JTO Clin Res Rep. 2024 Sep; 2024 Jul 6. PMID: 39282662.
- Genomic Landscape of Osteosarcoma of Bone in an Older-Aged Patient Population and Analysis of Possible Etiologies Based on Molecular Signature.Kaseb H, Tan C, Townsend JP, Costa J, Laskin WB. Genet Test Mol Biomarkers. 2024 Sep; 2024 Jul 25. PMID: 39052504.
- Alternative Payment Models and Performance in Federally Qualified Health Centers.Markowski J, Wallace J, Schlesinger M, Ndumele CD. JAMA Intern Med. 2024 Sep 1. PMID: 38976258.
- Medical Marijuana for Pain Management in Hospice Care as a Complementary Approach to Scheduled Opioids: A Single Arm Study.Zanker T, Sacco J, Prota J, Palma M, Viola Lee KA, Wang RR, Liang Y, Cunningham J, Mackary M, Ovchinnikova P. Am J Hosp Palliat Care. 2024 Sep; 2023 Dec 15. PMID: 38100655.
- Expression and clinicopathologic significance of HER2 and PD-L1 in high grade urothelial carcinoma of the urinary tract.Li P, Ni P, Haines GK, Si Q, Li X, Baskovich B. Int J Clin Exp Pathol. 2024; 2024 Aug 15. PMID: 39262437.
- Barriers to and facilitators of improving physical activity and nutrition behaviors during chemotherapy for breast cancer: a sequential mixed methods study.Puklin LS, Irwin ML, Sanft T, Ferrucci LM, Harrigan M, McGowan C, Cartmel B, Zupa M, Winer EP, Deyling M, Ligibel JA, Basen-Engquist K, Spiegelman D, Sharifi M. Support Care Cancer. 2024 Aug 14; 2024 Aug 14. PMID: 39141176.
- National age-specific mortality trends for cervical and breast cancers in urban-rural areas of China from 2009 to 2021: a population-based analysis.Li ML, Qi JL, Ma YQ, Shu W, Xiao HD, Wang LJ, Yin P, Guo HY, Vermund SH, Zhou MG, Hu YF. Mil Med Res. 2024 Aug 13; 2024 Aug 13. PMID: 39138529.
- Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway.Dudkina N, Park HB, Song D, Jain A, Khan SA, Flavell RA, Johnson CH, Palm NW, Crawford JM. Cell Chem Biol. 2024 Aug 9; 2024 Aug 9. PMID: 39163853.
- Exercise and nutrition to improve cancer Treatment-Related outcomes (ENICTO).Schmitz KH, Brown JC, Irwin ML, Robien K, Scott JM, Berger NA, Caan B, Cercek A, Crane TE, Evans SR, Ligibel JA, Meyerhardt JA, Agurs-Collins T, Basen-Engquist K, Bea JW, Cai SF, Cartmel B, Chinchilli VM, Demark-Wahnefried W, Dieli-Conwright CM, DiPietro L, Doerksen SE, Edelstein SL, Elena J, Evans W, Ferrucci LM, Foldi J, Freylersythe S, Furberg H, Jones LW, Levine R, Moskowitz CS, Owusu C, Penedo F, Rabin BA, Ratner E, Rosenzweig M, Salz T, Sanft T, Schlumbrecht M, Spielmann G, Thomson CA, Tjaden AH, Weiser MR, Yang S, Yu AF, Perna FM. J Natl Cancer Inst. 2024 Aug 8; 2024 Aug 8. PMID: 39118255.
- Association Between the Decipher Genomic Classifier and Prostate Cancer Outcome in the Real-world Setting.Leapman MS, Ho J, Liu Y, Filson C, Zhao X, Hakansson A, Proudfoot JA, Davicioni E, Martin DT, An Y, Seibert TM, Lin DW, Spratt DE, Cooperberg MR, Sprenkle PC, Ross AE. Eur Urol Oncol. 2024 Aug 3; 2024 Aug 3. PMID: 39098389.
- Treatment Access among Younger Medicaid Beneficiaries with Multiple Myeloma.Fiala MA, Ji M, Shih YH, Huber J, Wang M, Johnson KJ, Gasoyan H, Wang R, Colditz GA, Wang SY, Chang SH. Clin Lymphoma Myeloma Leuk. 2024 Aug 2; 2024 Aug 2. PMID: 39209567.
- Brief Report: Protease Inhibitors Versus Nonnucleoside Reverse Transcriptase Inhibitors and the Risk of Cancer Among People With HIV.Coburn SB, Pimentel N, Leyden W, Kitahata M, Moore RD, Althoff KN, Gill MJ, Lang R, Horberg MA, D'Souza G, Hussain SK, Dubrow R, Novak RM, Rabkin CS, Park LS, Sterling TR, Neugebauer RS, Silverberg MJ. J Acquir Immune Defic Syndr. 2024 Aug. PMID: 39720558.
- Smoking patterns by birth cohort in Argentina: an age-period-cohort population-based modeling study.Salgado MV, Mok Y, Jeon J, Jaffri M, Tam J, Holford TR, Sánchez-Romero LM, Meza R, Mejia R. Lancet Reg Health Am. 2024 Aug; 2024 Jun 21. PMID: 39006127.
- Perioperative Modified FOLFIRINOX for Resectable Pancreatic Cancer: A Nonrandomized Controlled Trial.Cecchini M, Salem RR, Robert M, Czerniak S, Blaha O, Zelterman D, Rajaei M, Townsend JP, Cai G, Chowdhury S, Yugawa D, Tseng R, Mejia Arbelaez C, Jiao J, Shroyer K, Thumar J, Kortmansky J, Zaheer W, Fischbach N, Persico J, Stein S, Khan SA, Cha C, Billingsley KG, Kunstman JW, Johung KL, Wiess C, Muzumdar MD, Spickard E, Aushev VN, Laliotis G, Jurdi A, Liu MC, Escobar-Hoyos L, Lacy J. JAMA Oncol. 2024 Aug 1. PMID: 38900452.
- ACO leakage among gynecologic cancer patients: Incidence, predictors, and impact on annual Medicare expenditure.Osazuwa-Peters OL, Greiner MA, Kaufman BG, Zambrano Guevara LM, Dinan M, Havrilesky L, Moss HA. Gynecol Oncol. 2024 Aug; 2024 May 23. PMID: 38788516.
- The association between dietary fiber intake and gastric cancer: a pooled analysis of 11 case-control studies.Collatuzzo G, Cortez Lainez J, Pelucchi C, Negri E, Bonzi R, Palli D, Ferraroni M, Zhang ZF, Yu GP, Lunet N, Morais S, López-Carrillo L, Zaridze D, Maximovitch D, Guevara M, Santos-Sanchez V, Vioque J, Garcia de la Hera M, Ward MH, Malekzadeh R, Pakseresht M, Hernández-Ramírez RU, Turati F, Rabkin CS, Liao LM, Sinha R, López-Cervantes M, Tsugane S, Hidaka A, Camargo MC, Curado MP, Zubair N, Kristjansson D, Shah S, La Vecchia C, Boffetta P. Eur J Nutr. 2024 Aug; 2024 Apr 30. PMID: 38687390.
- Incorporating prior information in gene expression network-based cancer heterogeneity analysis.Li R, Xu S, Li Y, Tang Z, Feng D, Cai J, Ma S. Biostatistics. 2024 Jul 29; 2024 Jul 29. PMID: 39074174.
- Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial.Puklin LS, Ferrucci LM, Harrigan M, McGowan C, Zupa M, Cartmel B, Li FY, Ligibel JA, Spiegelman D, Sharifi M, Sanft T, Irwin ML. Cancer. 2024 Jul 15; 2024 Mar 12. PMID: 38470431.
- Mapping the influence of hydrocarbons mixture on molecular mechanisms, involved in breast and lung neoplasms: in silico toxicogenomic data-mining.Abu-Bakar A, Ismail M, Zulkifli MZI, Zaini NAS, Shukor NIA, Harun S, Inayat-Hussain SH. Genes Environ. 2024 Jul 9; 2024 Jul 9. PMID: 38982523.
- High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study.Rogne T, Wang R, Wang P, Deziel NC, Metayer C, Wiemels JL, Chen K, Warren JL, Ma X. Lancet Planet Health. 2024 Jul. PMID: 38969477.
- Machine learning identifies prognostic subtypes of the tumor microenvironment of NSCLC.Yu D, Kane MJ, Koay EJ, Wistuba II, Hobbs BP. Sci Rep. 2024 Jul 1; 2024 Jul 1. PMID: 38951567.
- DNA methylation-based telomere length is associated with HIV infection, physical frailty, cancer, and all-cause mortality.Liang X, Aouizerat BE, So-Armah K, Cohen MH, Marconi VC, Xu K, Justice AC. Aging Cell. 2024 Jul; 2024 Apr 17. PMID: 38629454.
- Threats to social safety and neuro-inflammatory mechanisms underlying sexual orientation disparities in depression symptom severity: A prospective cohort study of young adults.Bränström R, Hatzenbuehler ML, Lattanner MR, Hollinsaid NL, McDade TW, Pachankis JE. Brain Behav Immun. 2024 Jul; 2024 Mar 27. PMID: 38548185.
- Estimation of multiple networks with common structures in heterogeneous subgroups.Qin X, Hu J, Ma S, Wu M. J Multivar Anal. 2024 Jul; 2024 Feb 13. PMID: 38433779.
- Association between diet quality and ovarian cancer risk and survival.Cao A, Esserman DA, Cartmel B, Irwin ML, Ferrucci LM. J Natl Cancer Inst. 2024 Jul 1. PMID: 38400738.
- Multiple myeloma incidence and mortality trends in the United States, 1999-2020.Zhu DT, Park A, Lai A, Zhang L, Attar H, Rebbeck TR. Sci Rep. 2024 Jun 24; 2024 Jun 24. PMID: 38914692.
- Growth characteristics of HCT116 xenografts lacking asparagine synthetase vary according to sex.Aladelokun O, Lu L, Zheng J, Yan H, Jain A, Gibson J, Khan SA, Johnson CH. Hum Genomics. 2024 Jun 17; 2024 Jun 17. PMID: 38886847.
- Rare Drivers at Low Prevalence with High Cancer Effects in T-Cell and B-Cell Pediatric Acute Lymphoblastic Leukemia.Mandell JD, Diviti S, Xu M, Townsend JP. Int J Mol Sci. 2024 Jun 15; 2024 Jun 15. PMID: 38928295.
- Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions.Dareng EO, Coetzee SG, Tyrer JP, Peng PC, Rosenow W, Chen S, Davis BD, Dezem FS, Seo JH, Nameki R, Reyes AL, Aben KKH, Anton-Culver H, Antonenkova NN, Aravantinos G, Bandera EV, Beane Freeman LE, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bernardini MQ, Bjorge L, Black A, Bogdanova NV, Bolton KL, Brenton JD, Budzilowska A, Butzow R, Cai H, Campbell I, Cannioto R, Chang-Claude J, Chanock SJ, Chen K, Chenevix-Trench G, Chiew YE, Cook LS, DeFazio A, Dennis J, Doherty JA, Dörk T, du Bois A, Dürst M, Eccles DM, Ene G, Fasching PA, Flanagan JM, Fortner RT, Fostira F, Gentry-Maharaj A, Giles GG, Goodman MT, Gronwald J, Haiman CA, Håkansson N, Heitz F, Hildebrandt MAT, Høgdall E, Høgdall CK, Huang RY, Jensen A, Jones ME, Kang D, Karlan BY, Karnezis AN, Kelemen LE, Kennedy CJ, Khusnutdinova EK, Kiemeney LA, Kjaer SK, Kupryjanczyk J, Labrie M, Lambrechts D, Larson MC, Le ND, Lester J, Li L, Lubiński J, Lush M, Marks JR, Matsuo K, May T, McLaughlin JR, McNeish IA, Menon U, Missmer S, Modugno F, Moffitt M, Monteiro AN, Moysich KB, Narod SA, Nguyen-Dumont T, Odunsi K, Olsson H, Onland-Moret NC, Park SK, Pejovic T, Permuth JB, Piskorz A, Prokofyeva D, Riggan MJ, Risch HA, Rodríguez-Antona C, Rossing MA, Sandler DP, Setiawan VW, Shan K, Song H, Southey MC, Steed H, Sutphen R, Swerdlow AJ, Teo SH, Terry KL, Thompson PJ, Vestrheim Thomsen LC, Titus L, Trabert B, Travis R, Tworoger SS, Valen E, Van Nieuwenhuysen E, Edwards DV, Vierkant RA, Webb PM, Weinberg CR, Weise RM, Wentzensen N, White E, Winham SJ, Wolk A, Woo YL, Wu AH, Yan L, Yannoukakos D, Zeinomar N, Zheng W, Ziogas A, Berchuck A, Goode EL, Huntsman DG, Pearce CL, Ramus SJ, Sellers TA, Freedman ML, Lawrenson K, Schildkraut JM, Hazelett D, Plummer JT, Kar S, Jones MR, Pharoah PDP, Gayther SA. Am J Hum Genet. 2024 Jun 6; 2024 May 8. PMID: 38723632.
- Development of a Longitudinal Prostate Cancer Transcriptomic and Clinical Data Linkage.Leapman MS, Ho J, Liu Y, Filson CP, Zhao X, Hakansson A, Proudfoot JA, Davicioni E, Martin DT, An Y, Seibert TM, Lin DW, Spratt DE, Cooperberg MR, Ross AE, Sprenkle PC. JAMA Netw Open. 2024 Jun 3; 2024 Jun 3. PMID: 38874922.
- Hypertension and Risk of Endometrial Cancer: A Pooled Analysis in the Epidemiology of Endometrial Cancer Consortium (E2C2).Habeshian TS, Peeri NC, De Vivo I, Schouten LJ, Shu XO, Cote ML, Bertrand KA, Chen Y, Clarke MA, Clendenen TV, Cook LS, Costas L, Dal Maso L, Freudenheim JL, Friedenreich CM, Gallagher G, Gierach GL, Goodman MT, Jordan SJ, La Vecchia C, Lacey JV, Levi F, Liao LM, Lipworth L, Lu L, Matias-Guiu X, Moysich KB, Mutter GL, Na R, Naduparambil J, Negri E, O'Connell K, O'Mara TA, Onieva Hernández I, Palmer JR, Parazzini F, Patel AV, Penney KL, Prizment AE, Ricceri F, Risch HA, Sacerdote C, Sandin S, Stolzenberg-Solomon RZ, van den Brandt PA, Webb PM, Wentzensen N, Wijayabahu AT, Wilkens LR, Xu W, Yu H, Zeleniuch-Jacquotte A, Zheng W, Du M, Setiawan VW. Cancer Epidemiol Biomarkers Prev. 2024 Jun 3. PMID: 38530242.
- Tobacco smoking, smoking cessation and life expectancy among people with HIV on antiretroviral therapy in South Africa: a simulation modelling study.Thielking AM, Fitzmaurice KP, Sewpaul R, Chrysanthopoulou SA, Dike L, Levy DE, Rigotti NA, Siedner MJ, Wood R, Paltiel AD, Freedberg KA, Hyle EP, Reddy KP. J Int AIDS Soc. 2024 Jun. PMID: 38924347.
- 'It Just Makes Sense to Me': A qualitative study exploring patient decision-making and experiences with prostate MRI during active surveillance for prostate cancer.Sutherland R, Gross CP, Ma X, Jeong F, Seibert TM, Cooperberg MR, Catalona WJ, Ellis SD, Loeb S, Schulman-Green D, Leapman MS. BJUI Compass. 2024 Jun; 2024 Apr 2. PMID: 38873351.
- Novel non-invasive molecular signatures for oral cavity cancer, by whole transcriptome and small non-coding RNA sequencing analyses: Predicted association with PI3K/AKT/mTOR pathway.Vageli DP, Doukas PG, Townsend JP, Pickering C, Judson BL. Cancer Med. 2024 Jun. PMID: 38819439.
- Synergistic Immunoregulation: harnessing CircRNAs and PiRNAs to Amplify PD-1/PD-L1 Inhibition Therapy.Han R, Rao X, Zhou H, Lu L. Int J Nanomedicine. 2024; 2024 May 28. PMID: 38828205.
- Partial Hepatectomy and Ablation for Survival of Early-Stage Hepatocellular Carcinoma Patients: A Bayesian Emulation Analysis.Wang J, Im Y, Wang R, Ma S. Life (Basel). 2024 May 22; 2024 May 22. PMID: 38929645.
- Information-incorporated sparse hierarchical cancer heterogeneity analysis.Han W, Zhang S, Ma S, Ren M. Stat Med. 2024 May 20; 2024 Mar 30. PMID: 38553996.
- Artificial intelligence assisted diagnosis of early tc markers and its application.Zhang L, Wong C, Li Y, Huang T, Wang J, Lin C. Discov Oncol. 2024 May 18; 2024 May 18. PMID: 38761260.
- The effect of a fermented soy beverage among patients with localized prostate cancer prior to radical prostatectomy.Lokeshwar SD, Ali A, Weiss TR, Reynolds J, Shuch BM, Ferencz T, Kyriakides TC, Mehal WZ, Brito J, Renzulli J, Leapman MS. BMC Urol. 2024 May 3; 2024 May 3. PMID: 38702664.
- A supervised Bayesian factor model for the identification of multi-omics signatures.Gygi JP, Konstorum A, Pawar S, Aron E, Kleinstein SH, Guan L. Bioinformatics. 2024 May 2. PMID: 38603606.
- Premarket Evidence and Postmarketing Requirements for Real-Time Oncology Review Indication Approvals.Mooghali M, Mohammad A, Wallach JD, Mitchell AP, Ross JS, Ramachandran R. JAMA Netw Open. 2024 May 1; 2024 May 1. PMID: 38691363.
- Long-term exposure to ambient fine particulate matter and risk of liver cancer in the NIH-AARP Diet and Health Study.Ma X, Fisher JA, McGlynn KA, Liao LM, Vasiliou V, Sun N, Kaufman JD, Silverman DT, Jones RR. Environ Int. 2024 May; 2024 Apr 5. PMID: 38636274.
- U.S. Women with Invasive Cervical Cancer: Characteristics and Potential Barriers to Prevention.Rosenblum HG, Gargano JW, Cleveland AA, Dahl RM, Park IU, Whitney E, Castilho JL, Sackey E, Niccolai LM, Brackney M, Debess E, Ehlers S, Bennett NM, Kurtz R, Unger ER, Markowitz LE. J Womens Health (Larchmt). 2024 May; 2024 Apr 12. PMID: 38608239.
- Dietary intake of vitamin C and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project.Sassano M, Seyyedsalehi MS, Collatuzzo G, Pelucchi C, Bonzi R, Ferraroni M, Palli D, Yu GP, Zhang ZF, López-Carrillo L, Lunet N, Morais S, Zaridze D, Maximovich D, Martín V, Castano-Vinyals G, Vioque J, González-Palacios S, Ward MH, Malekzadeh R, Pakseresht M, Hernández-Ramirez RU, López-Cervantes M, Negri E, Turati F, Rabkin CS, Tsugane S, Hidaka A, Lagiou A, Lagiou P, Camargo MC, Curado MP, Boccia S, La Vecchia C, Boffetta P. Gastric Cancer. 2024 May; 2024 Mar 4. PMID: 38436761.
- Digital Interventions to Support Lung Cancer Screening: A Systematic Review.Odole IP, Andersen M, Richman IB. Am J Prev Med. 2024 May; 2024 Jan 20. PMID: 38246408.
- Posttransplant Tertiary Lymphoid Organs.Ruddle NH. Transplantation. 2024 May 1; 2023 Nov 2. PMID: 37917987.
- Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes.Chen Z, Guo X, Tao R, Huyghe JR, Law PJ, Fernandez-Rozadilla C, Ping J, Jia G, Long J, Li C, Shen Q, Xie Y, Timofeeva MN, Thomas M, Schmit SL, Díez-Obrero V, Devall M, Moratalla-Navarro F, Fernandez-Tajes J, Palles C, Sherwood K, Briggs SEW, Svinti V, Donnelly K, Farrington SM, Blackmur J, Vaughan-Shaw PG, Shu XO, Lu Y, Broderick P, Studd J, Harrison TA, Conti DV, Schumacher FR, Melas M, Rennert G, Obón-Santacana M, Martín-Sánchez V, Oh JH, Kim J, Jee SH, Jung KJ, Kweon SS, Shin MH, Shin A, Ahn YO, Kim DH, Oze I, Wen W, Matsuo K, Matsuda K, Tanikawa C, Ren Z, Gao YT, Jia WH, Hopper JL, Jenkins MA, Win AK, Pai RK, Figueiredo JC, Haile RW, Gallinger S, Woods MO, Newcomb PA, Duggan D, Cheadle JP, Kaplan R, Kerr R, Kerr D, Kirac I, Böhm J, Mecklin JP, Jousilahti P, Knekt P, Aaltonen LA, Rissanen H, Pukkala E, Eriksson JG, Cajuso T, Hänninen U, Kondelin J, Palin K, Tanskanen T, Renkonen-Sinisalo L, Männistö S, Albanes D, Weinstein SJ, Ruiz-Narvaez E, Palmer JR, Buchanan DD, Platz EA, Visvanathan K, Ulrich CM, Siegel E, Brezina S, Gsur A, Campbell PT, Chang-Claude J, Hoffmeister M, Brenner H, Slattery ML, Potter JD, Tsilidis KK, Schulze MB, Gunter MJ, Murphy N, Castells A, Castellví-Bel S, Moreira L, Arndt V, Shcherbina A, Bishop DT, Giles GG, Southey MC, Idos GE, McDonnell KJ, Abu-Ful Z, Greenson JK, Shulman K, Lejbkowicz F, Offit K, Su YR, Steinfelder R, Keku TO, van Guelpen B, Hudson TJ, Hampel H, Pearlman R, Berndt SI, Hayes RB, Martinez ME, Thomas SS, Pharoah PDP, Larsson SC, Yen Y, Lenz HJ, White E, Li L, Doheny KF, Pugh E, Shelford T, Chan AT, Cruz-Correa M, Lindblom A, Hunter DJ, Joshi AD, Schafmayer C, Scacheri PC, Kundaje A, Schoen RE, Hampe J, Stadler ZK, Vodicka P, Vodickova L, Vymetalkova V, Edlund CK, Gauderman WJ, Shibata D, Toland A, Markowitz S, Kim A, Chanock SJ, van Duijnhoven F, Feskens EJM, Sakoda LC, Gago-Dominguez M, Wolk A, Pardini B, FitzGerald LM, Lee SC, Ogino S, Bien SA, Kooperberg C, Li CI, Lin Y, Prentice R, Qu C, Bézieau S, Yamaji T, Sawada N, Iwasaki M, Le Marchand L, Wu AH, Qu C, McNeil CE, Coetzee G, Hayward C, Deary IJ, Harris SE, Theodoratou E, Reid S, Walker M, Ooi LY, Lau KS, Zhao H, Hsu L, Cai Q, Dunlop MG, Gruber SB, Houlston RS, Moreno V, Casey G, Peters U, Tomlinson I, Zheng W. Nat Commun. 2024 Apr 26; 2024 Apr 26. PMID: 38670944.
- Endocrine disrupting chemical mixture exposure and risk of papillary thyroid cancer in U.S. military personnel: A nested case-control study.Denic-Roberts H, McAdam J, Sjodin A, Davis M, Jones R, Ward MH, Hoang TD, Ma S, Zhang Y, Rusiecki JA. Sci Total Environ. 2024 Apr 20; 2024 Feb 28. PMID: 38428594.
- Cohort study of patients with advanced cancer: outcomes associated with duration of antibiotic therapy for non-ventilator hospital-acquired pneumonia.Lee S, Benson J, Cohen A, Quagliarello V, Juthani-Mehta M, Datta R. Antimicrob Steward Healthc Epidemiol. 2024; 2024 Apr 18. PMID: 38655023.
- Immunotherapy utilization patterns in patients with advanced cancer and autoimmune disease.Li H, Huntington S, Gross C, Wang SY. PLoS One. 2024; 2024 Apr 16. PMID: 38625861.
- A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children.de Smith AJ, Wahlster L, Jeon S, Kachuri L, Black S, Langie J, Cato LD, Nakatsuka N, Chan TF, Xia G, Mazumder S, Yang W, Gazal S, Eng C, Hu D, Burchard EG, Ziv E, Metayer C, Mancuso N, Yang JJ, Ma X, Wiemels JL, Yu F, Chiang CWK, Sankaran VG. Cell Genom. 2024 Apr 10; 2024 Mar 26. PMID: 38537633.
- Characterization of accelerated approval status, trial endpoints and results, and recommendations in guidelines for oncology drug treatments from the National Comprehensive Cancer Network: cross sectional study.Mooghali M, Mitchell AP, Skydel JJ, Ross JS, Wallach JD, Ramachandran R. BMJ Med. 2024; 2024 Apr 5. PMID: 38596814.
Centers and other resources
- Yale Cancer Center (YCC)The Center provides the best approaches for the prevention, detection, diagnosis, and treatment of cancer.
- Yale Center for Analytical Sciences (YCAS)YCAS collaborative team provides expertise in the design, conduct, and analysis of health and health care studies, methodological development, and education and training.
- Yale-Griffin Prevention Research Center (PRC)The PRC works with community partners to develop and implement community-based approaches to prevent and control chronic diseases such as heart disease, diabetes, and cancer.