- December 04, 2025
YSPH study provides new insights into colorectal cancer
- November 17, 2025Source: MedPage Today
Here's what's driving late heart events in older cancer survivors
- November 15, 2025Source: The Washington Post
Study offers clues on rise of colorectal cancer in women under 50
- November 12, 2025
A dose of skin cancer prevention
Cancer
More people today die from cancer than from almost any other cause in the world. The challenges posed by cancer are immense and top scientists at the Yale School of Public Health are committed to reducing its toll.
The departments of Chronic Disease Epidemiology, Biostatistics and Health Policy and Management are heavily focused on a wide variety of cancer-related research, and the Department of Environmental Health Sciences is renowned for novel approaches to the study of how environmental exposures affect health outcomes. From key partnerships with the Yale Cancer Center to collaborative efforts locally and globally, YSPH scientists are taking significant steps toward preventing and treating a wide range of cancers. Today, research in cancer and other chronic diseases encompasses interdisciplinary teams committed to understanding cancer causation and etiology, prevention, screening and early detection, risk factors, environmental exposures, social determinants of health and survival.
A variety of technologies and approaches are used to detect mechanisms and characteristics of the many different types of cancer, including genomics, metabolomics, social and behavioral effects, evolutionary biology, biostatistical methodology and study design, and outcomes research.
The Yale School of Public Health maintains biospecimens and data from thousands of individuals in more than a dozen studies that can be made applied to future research. It also has partnerships with numerous international cancer researchers, and is the home of leading experts in clinical trial design and data management, and genomic and metabolic centers.
Recent Publications
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- ASO Visual Abstract: Financial Outlook thRough CAncer STorytelling (FOReCAST): Development of a Novel Video-Based Storytelling Intervention to Mitigate Financial Hardship Among Young Women with Breast Cancer.Hamid SA, Moses J, Lynch OF, Washington R, Dicks M, Greenup RA, Proussaloglou EM. Ann Surg Oncol. 2026 Feb. PMID: 41145938.
- Research Priorities and Future Directions in Cardio-Oncology.Mszar R, Ali A, Hull SC, Ferrucci LM, Baldassarre LA, Khera R, Irwin ML, Clasen SC. Curr Treat Options Oncol. 2026 Jan 4; 2026 Jan 4. PMID: 41484494.
- Molecular Signature of Cisplatin Resistance in Ovarian Cancer Identifies Therapeutic Opportunities for Re-sensitization.Mansour M, van Ginkel S, Alata M, Bani I, Elhussin I. J Cancer. 2026; 2026 Jan 1. PMID: 41438580.
- Personalized risk assessment of frailty in long-term cancer survivors.Forman R, Westvold SJ, Long JB, Fan J, Hyslop T, Conlin K, Jacobson S, Wang SY, Leapman MS, Cecchini M, Leeds I, Spees L, Presley C, Yasin F, Taylor M, Kwaramba T, Gross CP, Oeffinger K, Dinan MA. J Geriatr Oncol. 2026 Jan; 2025 Nov 29. PMID: 41319472.
- Financial Outlook thRough CAncer STorytelling (FOReCAST): Development of a Novel Video-Based Storytelling Intervention to Mitigate Financial Hardship Among Young Women with Breast Cancer.Hamid SA, Moses J, Lynch OF, Washington R, Dicks M, Greenup RA, Proussaloglou EM. Ann Surg Oncol. 2026 Jan; 2025 Sep 24. PMID: 40993463.
- Effect of a lifestyle intervention during chemotherapy for breast cancer on quality of life.Puklin LS, Li FY, Ferrucci LM, Cartmel B, Harrigan M, Mcgowan C, Zupa M, Ligibel JA, Sanft T, Irwin ML. JNCI Cancer Spectr. 2025 Dec 26; 2025 Dec 26. PMID: 41452765.
- Body Mass Index and Chemotherapy Completion among Patients Newly Diagnosed with Ovarian Cancer.Cao A, Cartmel B, Ratner E, Li FY, Schlumbrecht MP, Kumar A, Crane TE, Esserman DA, Irwin ML, Ferrucci LM. JNCI Cancer Spectr. 2025 Dec 24; 2025 Dec 24. PMID: 41442446.
- Lipophilic Statins Deplete GPX4 to Promote Ferroptosis and Sensitize Cancer Cells to Immune Checkpoint Blockade.Talty R, Brooks VT, McGeary MK, Milette S, Zheng S, Flem-Karlsen K, Daniels A, Deshmukh M, Park K, Caraccio W, Yan H, Echeandia-Francis C, McNamara M, Hong S, Kirwin DS, Olino K, Johnson CH, Bosenberg M, Micevic G, Roy SF. Mol Cancer Ther. 2025 Dec 22; 2025 Dec 22. PMID: 41423587.
- Why Americans are Dying Younger? NIH Is Not the Problem. Our Broken Healthcare Delivery Is.Ignacio RB, Pagkas-Bather J, Gonsalves G, Gianella S. J Infect Dis. 2025 Dec 20; 2025 Dec 20. PMID: 41420662.
- Why Americans are Dying Younger? NIH Is Not the Problem. Our Broken Healthcare Delivery Is.Ignacio RB, Pagkas-Bather J, Gonsalves G, Gianella S. Clin Infect Dis. 2025 Dec 20; 2025 Dec 20. PMID: 41420651.
- Costs and benefits of early access to new cancer drugs through the US Food and Drug Administration's accelerated approval pathway: retrospective observational study and economic evaluation.Naci H, Shahzad M, Murphy P, Zhang Y, Costa R, Ross JS, Wagner AK. BMJ Med. 2025; 2025 Dec 16. PMID: 41431468.
- The impact of genetic and environmental risk factors on adverse liver outcomes.Zhang X, Zhao L, Campbell PT, Chen Y, Fang A, Liu Z, Li X, Yang W, Fan J, Petrick JL, McGlynn KA, Lai M, Zhang X. Int J Cancer. 2025 Dec 4; 2025 Dec 4. PMID: 41345374.
- HOXA13 overexpression is associated with poor prognosis in colorectal liver metastases(☆).Su DG, Kurbatov V, Wang X, Zeng Z, Paty PB, Johnson CH, Lu J, Khan SA. Surg Oncol Insight. 2025 Dec; 2025 Sep 29. PMID: 41409782.
- Trends in Colon Cancer Colectomy Volume and Inpatient Costs, 2018-2023: A Medicare Analysis.Newton LE, Korves C, Zwain G, Fowler XP, Bellamkonda K, Rosa S, Denny J, Huynh J, Weinberger DM, Justice A, Vashi A, Goodney PP, Wilson MZ, Davies L. J Surg Res. 2025 Dec; 2025 Dec 2. PMID: 41337807.
- Association between prostate radiotherapy and survival among patients with metastatic prostate cancer by extent of disease burden.Palencia PS, Smani S, Zhao X, Kandala K, Sivanesan N, Cavallo JA, Roessler N, Aneja S, An Y, Miszczyk M, Leapman MS. Radiother Oncol. 2025 Dec; 2025 Sep 21. PMID: 40987387.
- Distinct metabolic and genetic alterations in tumors from early-onset versus late-onset colorectal cancer.Janak A, Jain A, Garcia-Milian R, Aladelokun O, Ma X, Paty PB, Khan SA, Johnson CH. Free Radic Biol Med. 2025 Dec 1; 2025 Aug 25. PMID: 40865779.
- Tracing the evolution of single-cell 3D genomes in Kras-driven cancers.Liu M, Jin S, Agabiti SS, Jensen TB, Yang T, Radda JSD, Ruiz CF, Baldissera G, Rajaei M, Li FY, Townsend JP, Muzumdar MD, Wang S. Nat Genet. 2025 Dec; 2025 Aug 18. PMID: 40825871.
- Addressing conceptual and design gaps in the oncology nutrition evidence base during chemotherapy: contributions of the Exercise and Nutrition Interventions to Improve Cancer Treatment-Related Outcomes Consortium.Compton SLE, Wopat H, Lopez-Pentecost M, Agurs-Collins T, Brown JC, Caan B, Demark-Wahnefried W, Elena JW, Ferrucci LM, McGowan C, Puklin LS, Schmitz KH, Thomson CA, Robien K, Crane TE. J Natl Cancer Inst. 2025 Dec 1. PMID: 40680173.
- Barriers and facilitators to a combined strategy of HPV vaccination and cervical cancer screening among Mexican women.León-Maldonado L, Cabral A, Pages G, Brown B, Allen-Leigh B, Lazcano-Ponce E, Xavier Bosch F, Spiegelman D, Torres-Ibarra L, Hernández-Ramírez RU, Egger E, Rivera-Paredez B, Salmerón J. Hum Vaccin Immunother. 2025 Dec; 2025 Apr 2. PMID: 40172917.
- Patient Experiences in Accessing Reproductive Health Services for Women With Cognitive, Intellectual, and Developmental Disabilities: A Systematic Review.Chang C, Carandang RR, Silverberg J, Surkis C, Cunningham SD, Wang K, Qasba N. Womens Health Issues. 2025 Nov 21; 2025 Nov 21. PMID: 41274839.
- TCPGdb: A comprehensive T cell perturbation genomics database for identification of critical T cell regulators.Dong C, Zhang F, Tang K, Verma N, Zhu X, Feng D, Cai J, Zhao H, Chen S. Cancer Immunol Res. 2025 Nov 21; 2025 Nov 21. PMID: 41270225.
- Exposure to nitrosatable drugs during pregnancy and childhood cancer: A cohort study in Taiwan.Deng C, Hu YH, Sirirungreung A, Chock EY, Liew Z, Ritz B, Lee PC, Heck JE. Int J Cancer. 2025 Nov 7; 2025 Nov 7. PMID: 41203947.
- Semaglutide and Tirzepatide Prescribing for Obesity in Patients With Preexisting Comorbid Cancers.Kim C, Dinan MA, Robinson TJ, Ross JS, Jastreboff AM, Krumholz HM, Lu Y. JAMA Oncol. 2025 Nov 6; 2025 Nov 6. PMID: 41196576.
- Risk of Late-Onset Depression in Long-Term Survivors of Breast, Prostate, and Colorectal Cancer.Taylor M, Westvold SJ, Long JB, Hyslop T, Silber A, Forman R, Yasin F, Kwaramba T, Wang SY, Leapman MS, Cecchini M, Leeds I, Spees L, Wheeler SB, Gross CP, Oeffinger K, Dinan MA. JAMA Netw Open. 2025 Nov 3; 2025 Nov 3. PMID: 41296485.
- Interprovider Variation in Initiation of Bone-Modifying Agents for Patients With Prostate Cancer.Mitchell AP, Salner A, Palyca P, Farooki A, Persaud S, Chakraborty N, Bhamidipati D, Klimchuk M, Dinan MA, Leapman MS, Lipitz-Snyderman A, Hamid A, Ostroff JS, Morris MJ. JCO Oncol Pract. 2025 Nov 3; 2025 Nov 3. PMID: 41183247.
- Molecular Reactivity in Maternal Pregnancy Blood and Neonatal Dried Blood Spots Is Associated with the Risk of Pediatric Acute Lymphoblastic Leukemia.Petrick LM, Imani P, Yu M, Dolios G, Dudoit S, Morimoto LM, Ma X, Wiemels JL, Metayer C. Cancer Epidemiol Biomarkers Prev. 2025 Nov 3. PMID: 40932331.
- KRAS G12C-associated immunotherapy benefit in NSCLC is substantially mediated by tobacco-induced tumor mutation burden, not allele-specific effects.Liu M, Townsend JP. Lung Cancer. 2025 Nov; 2025 Sep 16. PMID: 41027389.
- Clinical effectiveness of HPV vaccine by age at vaccination: a matched case-control study.Oliveira CR, Shapiro ED, Sheth SS, Ellingson MK, Johnson NP, Sullivan EL, Querec TD, Unger ER, Niccolai LM. Lancet Reg Health Am. 2025 Nov; 2025 Sep 16. PMID: 41019517.
- Feasibility, safety and outcomes of patients with newly diagnosed acute myeloid leukemia discharged 'early' after intensive induction.Hunter CJ, Cheng W, Bewersdorf JP, Boddu P, Browning S, Halene S, Parker T, Huntington SF, Kothari S, Mendez L, Neparidze N, Sethi T, Barbarotta L, Podoltsev NA, Zeidan AM, Shallis RM. Leuk Lymphoma. 2025 Oct 29; 2025 Oct 29. PMID: 41160735.
- The impact of Indigenous American-like ancestry on the risk of acute lymphoblastic leukemia in Hispanic/Latino children.Langie J, Chan TF, Yang W, Kang AY, Morimoto L, Stram DO, Mancuso N, Ma X, Metayer C, Lupo PJ, Rabin KR, Scheurer ME, Wiemels JL, Yang JJ, de Smith AJ, Chiang CWK. HGG Adv. 2025 Oct 25; 2025 Oct 25. PMID: 41261530.
- Effect of prescribing and deprescribing oxycodone on pain and function in a mouse model of osteoarthritis: impact of polypharmacy and sex on response.Mach J, Blaker CL, Winters B, Otsu Y, Clarke EC, Allore H, Wyk BV, Winardi K, Peel R, Gregson CW, Assareh N, Kourieh M, Hilmer SN. bioRxiv. 2025 Oct 23; 2025 Oct 23. PMID: 41279379.
- Evaluation of disparities in the incidence, presentation, and treatment of pediatric differentiated thyroid cancer in the United States (2000-2022).Ning X, Wang R, Ogilvie J, Dinauer C, Ma X, Deziel NC. PLoS One. 2025; 2025 Oct 16. PMID: 41100458.
- Mediterranean diet and Cantonese cuisine for human health: report from a Sino-Italian bilateral meeting.Maggi S, Ecarnot F, Gianfredi V, Nucci D, Veronese N, Lei L, Hu M, Avart C, Capurso A, Chen L, Hachem F, Yang H, Logrieco AF, Magli M, Mai Q, Palla F, Predieri S, Rizzoli R, Rogoli D, Santino A, Silano M, Simeoni M, Trichopoulou A, Volpe R, Wang Y, Wu J, Xiaohui M, Chen X, Zhang X, Yujie L, Zanetti M, Picci G. Aging Clin Exp Res. 2025 Oct 11; 2025 Oct 11. PMID: 41075017.
- Molecular Biomarker Testing Patterns and Turnaround Time in US Patients With Advanced Non-Small Cell Lung Cancer.Wang X, Lee DH, Yang SC, Li Y, Soulos PR, Gross CP, Wang SY, Chiang AC. J Natl Compr Canc Netw. 2025 Oct 10; 2025 Oct 10. PMID: 41072474.
- Metabolomic Biomarkers of Rest-Activity Rhythms in Older Women: Results from the Women's Health Initiative (WHI) Study.Zhang L, Yeung CHC, Viola Lee KA, Shadyab AH, LaCroix A, Stone KL, Yaffe K, Hayden KM, Casanova R, Rapp SR, Chen JC, Baker L, Manson JE, Huang Y, Xiao Q. Sleep. 2025 Oct 10; 2025 Oct 10. PMID: 41071097.
- Cardiovascular risk in long-term survivors of breast, prostate, colon, and rectal cancer.Westvold SJ, Long JB, Fan J, Kc M, Hyslop T, Conlin K, Jacobson S, Silber A, Wang SY, Leapman MS, Leeds I, Spees L, Wheeler SB, Gross CP, Oeffinger K, Dinan MA. J Natl Cancer Inst. 2025 Oct 9; 2025 Oct 9. PMID: 41069232.
- Cost-Effectiveness and Evidence Gaps Surrounding PSMA-PET for Recurrent Prostate Cancer Evaluation.Kunst N, Long JB, Sprenkle PC, Kim IY, Saperstein L, Rabil M, Ghaffar U, Karnes RJ, Ma X, Gross CP, Wang SY, Leapman MS. JAMA Netw Open. 2025 Oct 1; 2025 Oct 1. PMID: 41134573.
- Changes in Colorectal Cancer Screening Modalities Among Insured Individuals.Siddique S, Wang R, May FP, Baum LVM, Gross CP, Ma X. JAMA Netw Open. 2025 Oct 1; 2025 Oct 1. PMID: 41118161.
- Ordinal Sparse Neural Networks for Modeling Gene- and Imaging-Environment Interactions.Xue J, Xu Y, Li J, Ma S, Fang K. Stat Med. 2025 Oct. PMID: 41105049.
- Psychosocial Risk Factors and Perceived Well-Being in Survivors of Gastrointestinal Cancer.Butensky SD, Schultz KS, Godfrey EL, Kim J, Sanft T, Johnson CH, Leeds IL, Khan SA. Psychooncology. 2025 Oct. PMID: 41068065.
- From Lymphotoxin to Tertiary Lymphoid Structures and Beyond.Ruddle NH. Immunol Rev. 2025 Oct. PMID: 41020546.
- Colorectal cancer molecular profiling: Opportunities for early detection.Sala A, van den Driest L, Rattray NJW, Johnson CH, Cameron JM, Khan SA, Palmer DS, Baker MJ. Clin Transl Med. 2025 Oct. PMID: 41020351.
- Opioid prescribing trends and pain scores among adult patients with cancer in a large health system.Baum LVM, Soulos PR, Kc M, Jeffery MM, Ruddy KJ, Lerro CC, Lee H, Graham DJ, Rivera DR, Liberatore M, Leapman MS, Jairam V, Dinan MA, Gross CP, Park HS. Cancer. 2025 Oct 1. PMID: 40977160.
- Diet and Prevention of Cardiovascular Disease and Cancer: JACC: CardioOncology State-of-the-Art Review.Hull SC, Mszar R, Ostfeld RJ, Ferrucci LM, Mucci LA, Giovannucci E, Loeb S. JACC CardioOncol. 2025 Oct; 2025 Aug 29. PMID: 40879583.
- Factors Associated With Timely Receipt of Colposcopy After Abnormal Cervical Cancer Screening.Patel AV, Qiu W, Sartor R, Wilcox M, Jones BA, Hernandez-Ramirez RU, Tang W, Megiel S, Girgis A, Foster J, Tong G, Spiegelman D, Sheth SS. J Low Genit Tract Dis. 2025 Oct 1; 2025 Jul 16. PMID: 40631578.
- Clinicopathologic Features of Untreated Colorectal Cancer with Acellular Mucin-Only Lymph Nodes.Luo W, Hu S, Riahi IR, Wang HL, Shaker N, Abukhiran I, Wang T, Polydorides AD, Akinsanya A, González IA, Hagen C, Graham RP, Lisovsky M, Longacre TA, Challa B, Chen W, Harter D, Beech C, Najibi M, Cao W, Lee M, Lagana SM, Liao X, Setia N, Westbrook LM, Chandan VS, Choi WT, Ding X, Gonzalez RS, Gopal P, Lee H, Navale P, Liu X, Panarelli NC, Yang Z, Drage MG, Song Z, Li F, Nagtegaal ID, Zhang X. Mod Pathol. 2025 Oct; 2025 Jun 11. PMID: 40513988.
- Changes in Use, Cost, and Value of Breast Cancer Screening Among Older Women in the US.Richman I, Long JB, Lindsay ME, Fendrick AM, Kyanko K, Gross CP. J Gen Intern Med. 2025 Sep 23; 2025 Sep 23. PMID: 40987968.
- Long-Term Outcomes and Cost-Effectiveness of Artificial Intelligence for Breast Cancer Screening: A Modeling Study.Andersen M, Kunst N, Richman IB. Value Health. 2025 Sep 20; 2025 Sep 20. PMID: 40983310.
- "A Double-Edged Sword": Influence of the 21st Century Cures Act on the Childhood, Adolescent, and Young Adult Cancer Care Experience.Lindsay ME, Clappier M, de Oliveira S, Gleeson D, Feifer D, O'Bryan SK, Kessler A, Mali N, Crabtree VM, Dean SM, Campbell PK, Snaman JM, Kaye EC, Ananth P. J Natl Compr Canc Netw. 2025 Sep 15; 2025 Sep 15. PMID: 40953607.
- Comparative Risk of Adverse Pancreatic Events With GLP-1 Receptor Agonists, SGLT2 Inhibitors, DPP4 Inhibitors, and Sulfonylureas Among Adults With Type 2 Diabetes at Moderate Cardiovascular Disease Risk.Kalathiya UN, Herrin J, Swarna KS, Deng Y, Polley EC, Neumiller JJ, Galindo RJ, Umpierrez GE, Ross JS, Mickelson MM, McCoy RG. Endocr Pract. 2025 Sep 11; 2025 Sep 11. PMID: 40945659.
- High MGMT expression identifies aggressive colorectal cancer with distinct genomic features and immune evasion properties.Zhang JY, Rajendran BK, Desai SS, Gibson J, DiPalermo J, LoRusso P, Kong Y, Zhao H, Cecchini M, Schalper KA. J Immunother Cancer. 2025 Sep 10; 2025 Sep 10. PMID: 40935566.
- Author Correction: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, Delgado MK, Lee JM, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Arun BK, Arver B, Bandera EV, Barile M, Barkardottir RB, Barrowdale D, Beckmann MW, Benitez J, Berchuck A, Bisogna M, Bjorge L, Blomqvist C, Blot W, Bogdanova N, Bojesen A, Bojesen SE, Bolla MK, Bonanni B, Børresen-Dale AL, Brauch H, Brennan P, Brenner H, Bruinsma F, Brunet J, Buhari SA, Burwinkel B, Butzow R, Buys SS, Cai Q, Caldes T, Campbell I, Cannioto R, Chang-Claude J, Chiquette J, Choi JY, Claes KBM, Cook LS, Cox A, Cramer DW, Cross SS, Cybulski C, Czene K, Daly MB, Damiola F, Dansonka-Mieszkowska A, Darabi H, Dennis J, Devilee P, Diez O, Doherty JA, Domchek SM, Dorfling CM, Dörk T, Dumont M, Ehrencrona H, Ejlertsen B, Ellis S, Engel C, Lee E, Evans DG, Fasching PA, Feliubadalo L, Figueroa J, Flesch-Janys D, Fletcher O, Flyger H, Foretova L, Fostira F, Foulkes WD, Fridley BL, Friedman E, Frost D, Gambino G, Ganz PA, Garber J, García-Closas M, Gentry-Maharaj A, Ghoussaini M, Giles GG, Glasspool R, Godwin AK, Goldberg MS, Goldgar DE, González-Neira A, Goode EL, Goodman MT, Greene MH, Gronwald J, Guénel P, Haiman CA, Hall P, Hallberg E, Hamann U, Hansen TVO, Harrington PA, Hartman M, Hassan N, Healey S, Heitz F, Herzog J, Høgdall E, Høgdall CK, Hogervorst FBL, Hollestelle A, Hopper JL, Hulick PJ, Huzarski T, Imyanitov EN, Isaacs C, Ito H, Jakubowska A, Janavicius R, Jensen A, John EM, Johnson N, Kabisch M, Kang D, Kapuscinski M, Karlan BY, Khan S, Kiemeney LA, Kjaer SK, Knight JA, Konstantopoulou I, Kosma VM, Kristensen V, Kupryjanczyk J, Kwong A, de la Hoya M, Laitman Y, Lambrechts D, Le N, De Leeneer K, Lester J, Levine DA, Li J, Lindblom A, Long J, Lophatananon A, Loud JT, Lu K, Lubinski J, Mannermaa A, Manoukian S, Le Marchand L, Margolin S, Marme F, Massuger LFAG, Matsuo K, Mazoyer S, McGuffog L, McLean C, McNeish I, Meindl A, Menon U, Mensenkamp AR, Milne RL, Montagna M, Moysich KB, Muir K, Mulligan AM, Nathanson KL, Ness RB, Neuhausen SL, Nevanlinna H, Nord S, Nussbaum RL, Odunsi K, Offit K, Olah E, Olopade OI, Olson JE, Olswold C, O'Malley D, Orlow I, Orr N, Osorio A, Park SK, Pearce CL, Pejovic T, Peterlongo P, Pfeiler G, Phelan CM, Poole EM, Pylkäs K, Radice P, Rantala J, Rashid MU, Rennert G, Rhenius V, Rhiem K, Risch HA, Rodriguez G, Rossing MA, Rudolph A, Salvesen HB, Sangrajrang S, Sawyer EJ, Schildkraut JM, Schmidt MK, Schmutzler RK, Sellers TA, Seynaeve C, Shah M, Shen CY, Shu XO, Sieh W, Singer CF, Sinilnikova OM, Slager S, Song H, Soucy P, Southey MC, Stenmark-Askmalm M, Stoppa-Lyonnet D, Sutter C, Swerdlow A, Tchatchou S, Teixeira MR, Teo SH, Terry KL, Terry MB, Thomassen M, Tibiletti MG, Tihomirova L, Tognazzo S, Toland AE, Tomlinson I, Torres D, Truong T, Tseng CC, Tung N, Tworoger SS, Vachon C, van den Ouweland AMW, van Doorn HC, van Rensburg EJ, Van't Veer LJ, Vanderstichele A, Vergote I, Vijai J, Wang Q, Wang-Gohrke S, Weitzel JN, Wentzensen N, Whittemore AS, Wildiers H, Winqvist R, Wu AH, Yannoukakos D, Yoon SY, Yu JC, Zheng W, Zheng Y, Khanna KK, Simard J, Monteiro AN, French JD, Couch FJ, Freedman ML, Easton DF, Dunning AM, Pharoah PD, Edwards SL, Chenevix-Trench G, Antoniou AC, Gayther SA. Nat Commun. 2025 Sep 8; 2025 Sep 8. PMID: 40925936.
- A systematic review of residential proximity to upstream oil and gas development and childhood, adolescent and young adult cancer risk.Stewart EC, Johnson NP, Clark CJ, Metayer C, Deziel NC. Curr Probl Pediatr Adolesc Health Care. 2025 Sep; 2025 Sep 19. PMID: 40975664.
- Diagnostic Evaluation for Abnormal Uterine Bleeding at Emergency Departments in the United States.Huang W, Ma X, Clark M, Xu X. Womens Health Issues. 2025 Sep-Oct; 2025 Sep 1. PMID: 40897603.
- GE-IA-NAM: gene-environment interaction analysis via imaging-assisted neural additive model.Li J, Xu Y, Ma S, Fang K. Bioinformatics. 2025 Sep 1. PMID: 40880282.
- Predictors of LexisNexis residential history availability and registry data concordance for childhood cancer research.Binczewski NR, Morimoto LM, Wiemels JL, Ma X, Metayer C, Vieira VM. JNCI Cancer Spectr. 2025 Sep 1. PMID: 40713918.
- Joint modeling of mixed outcomes using a rank-based sparse neural network.Xue J, Xu Y, Li J, Ma S, Fang K. J Biomed Inform. 2025 Sep; 2025 Jul 5. PMID: 40623577.
- Optimizing participant and community engagement in cancer genomic sequencing research.Crossnohere NL, Schuster ALR, Blair CK, Bland H, Carpten JD, Claus EB, Colditz GA, Diehl D, Ding L, Drake BF, Fields RC, George S, Janeway K, Kim H, Lenz HJ, Mack JW, Ricker C, Stern MC, Sussman A, Trent J, Van Allen E, Verhaak R, Willman C, Bridges JFP, Mishra SI, Kwan BM. Genet Med. 2025 Sep; 2025 Jun 11. PMID: 40517303.
- Phase II Trial of Chemotherapy, Cetuximab, and Erlotinib in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck.Bhatia A, Mehra R, Bauman J, Khan SA, Wei W, Neumeister V, Sandoval-Schaefer T, Alpaugh RK, Lango M, Rimm DL, Ridge JA, Burtness B. Head Neck. 2025 Sep; 2025 Apr 1. PMID: 40166973.
- Insult to Injury: Cross-Sectional Analysis of Preoperative Psychosocial Vulnerabilities in Adult Patients Undergoing Major Elective Cancer Surgery.Schultz KS, Linhares SM, Park EY, Godfrey EL, Dhanda U, Epstein EJ, Blake KBT, Huang Y, Zaheer H, Leeds IL. Cancers (Basel). 2025 Aug 30; 2025 Aug 30. PMID: 40940955.
- Cancer care interventions for forcibly displaced populations in low- and middle-income countries of the Middle East and North African region affected by humanitarian crises: Protocol for a scoping review.Havlik AL, Ahmed Z, Chadwick PS, Nyhan K, Khoshnood K. PLoS One. 2025; 2025 Aug 18. PMID: 40824891.
- Smart CAR-T Nanosymbionts: archetypes and proto-models.Baena JC, Victoria JS, Toro-Pedroza A, Aragón CC, Ortiz-Guzman J, Garcia-Robledo JE, Torres D, Rios-Serna LJ, Albornoz L, Rosales JD, Cañas CA, Adolfo Cruz-Suarez G, Osorio FO, Fleitas T, Laponogov I, Loukanov A, Veselkov K. Front Immunol. 2025; 2025 Aug 12. PMID: 40873579.
- Discovery of a Widespread Polyamine-Low-Molecular-Weight Thiol Hybrid Pathway in Clostridioides difficile.Hunt RL, Oh J, Jain A, Kuo TH, Berardi D, Jian W, Song D, Wu Q, Goodman AL, Palm NW, Zimmermann M, Johnson CH, Crawford JM. ACS Infect Dis. 2025 Aug 8; 2025 Jul 17. PMID: 40671632.
- Longitudinal graphics of patient-reported physical function in patients treated for hematologic malignancies.Thanarajasingam G, Bhatnagar V, Noble BN, Chen TY, Fiero MH, Hoffman R, Jeffery M, Mazza GL, Mascarenhas J, Mesa R, Murugappan M, Ross J, Sidana S, Warsame R, Kluetz PG, Dueck AC. BMC Med Res Methodol. 2025 Aug 7; 2025 Aug 7. PMID: 40775758.
- Updated CP*Trends: an online tool to compare cohort and period trends across cancer sites.Holford TR, Chen HS, Kane MJ, Krapcho M, Annett D, Esclamado L, Melkonyan A, Feuer EJ. Am J Epidemiol. 2025 Aug 5. PMID: 39475089.
- Non-communicable disease care for persons living with HIV in Peru: A national physician cross-sectional study.Slotkin R, Granda D, Cabrera D, Benites CM, Garcia PJ, Hsieh E. PLOS Glob Public Health. 2025; 2025 Aug 4. PMID: 40758733.
- Bayesian Counterfactual Machine Learning Individualizes Radiation Modality Selection to Mitigate Immunosuppression.Yu D, Kane MJ, Chen Y, Lin SH, Mohan R, Hobbs BP. JCO Clin Cancer Inform. 2025 Aug; 2025 Sep 8. PMID: 40920994.
- GWAS meta-analysis identifies five susceptibility loci for endometrial cancer.Ramachandran D, Wang X, Laisk T, Zheng Y, Ingold N, Canson DM, Kho PF, Naumann BJ, Chapman CJ, Bousset K, Krause AV, Schürmann P, Wieland B, Hanel P, Hülse F, Häfner N, Runnebaum I, Dubrowinskaja N, Turmanov N, Yugay T, Yessimsiitova ZB, Amant F, Annibali D, Beckmann MW, Bodelon C, Buchanan DD, Chen C, Clarke MA, Cook LS, De Vivo I, De Wispelaere W, Du M, Easton DF, Emons J, Fasching PA, Friedenreich CM, Gallagher G, Giles GG, Goode EL, Harris HR, Hunter DJ, Kolin DL, Kraft P, Lacey JV, Lambrechts D, Lu L, Mutter GL, Naduparambil J, O'Connell K, Patel AV, Pharoah PDP, Rebbeck TR, Ricceri F, Risch HA, Ruebner M, Sacerdote C, Scott RJ, Setiawan VW, Shu XO, Southey MC, Tham E, Tomlinson I, Turman C, Wentzensen N, Xu W, Yu H, Zheng W, Spurdle AB, Yarden Y, Mägi R, Hillemanns P, Glubb DM, Dörk T, O'Mara TA. EBioMedicine. 2025 Aug; 2025 Jul 8. PMID: 40633141.
- Lessons learned from aldehyde dehydrogenases as non-P450 aldehyde-oxidizing enzymes: implications for the 'exposome' and human health.Lisgara A, Thompson DC, Nebert DW, Vasiliou V. Expert Opin Drug Metab Toxicol. 2025 Aug; 2025 Jul 2. PMID: 40591371.
- Risk of Thyroid Tumors With GLP-1 Receptor Agonists: A Retrospective Cohort Study.Morales DR, Bu F, Viernes B, DuVall SL, Matheny ME, Simon KR, Falconer T, Richter LR, Ostropolets A, Lau WCY, Man KKC, Chattopadhyay S, Mathioudakis N, Minty E, Nishimura A, Sun F, Yin C, Seager SL, Chai Y, Zhou JJ, Lu Y, Reyes C, Pistillo A, Duarte-Salles T, Blacketer C, Schuemie MJ, Ryan PB, Krumholz HM, Hripcsak G, Khera R, Suchard MA. Diabetes Care. 2025 Aug 1. PMID: 40465422.
- Association Between the Decipher Genomic Classifier and Prostate Cancer Outcome in the Real-world Setting.Leapman MS, Ho J, Liu Y, Filson C, Zhao X, Hakansson A, Proudfoot JA, Davicioni E, Martin DT, An Y, Seibert TM, Lin DW, Spratt DE, Cooperberg MR, Sprenkle PC, Ross AE. Eur Urol Oncol. 2025 Aug; 2024 Aug 3. PMID: 39098389.
- Retraction Note: Tiliroside as a CAXII inhibitor suppresses liver cancer development and modulates E2Fs/Caspase-3 axis.Han R, Yang H, Lu L, Lin L. Sci Rep. 2025 Jul 29; 2025 Jul 29. PMID: 40730839.
- Tobacco smoke alters the trajectory of lung adenocarcinoma evolution via effects on somatic selection and epistasis.Dasari K, Alfaro-Murillo JA, Townsend JP. bioRxiv. 2025 Jul 25; 2025 Jul 25. PMID: 40777438.
- Applying multilevel selection to understand cancer evolution and progression.Laplane L, Lamoureux A, Richker HI, Marquez Alcaraz G, Fortunato A, Shaffer Z, Aktipis A, Mischel PS, Plutynski A, Townsend JP, Maley CC. PLoS Biol. 2025 Jul; 2025 Jul 18. PMID: 40680084.
- Machine Learning Risk Stratification for Older Breast Cancer Survivors: Clinical Care Implications.Wheeler SB, Rotter J, Spees LP, Biddell CB, Trogdon JG, Alfano CM, Mayer DK, Dinan MA, Nekhlyudov L, Birken SA. Health Serv Res. 2025 Jul 16; 2025 Jul 16. PMID: 40671264.
- Extending Cancer Survival with Exercise - Time for Oncology to Act.Irwin ML. N Engl J Med. 2025 Jul 3. PMID: 40601943.
- Distribution of copy number alterations and impact of chromosome arm call thresholds for meningioma.Patel RV, Ghosh HS, Meredith DM, Ryall S, Claus EB, Beroukhim R, Ligon AH, Santagata S, Bi WL. Nat Commun. 2025 Jul 2; 2025 Jul 2. PMID: 40603304.
- Robust Transfer Learning for High-Dimensional GLM Using γ -Divergence With Applications to Cancer Genomics.Xu F, Ma S, Zhang Q, Xu Y. Stat Med. 2025 Jul. PMID: 40662636.
- Exercise effects on symptoms of depression and anxiety vary by patient, clinical, and intervention characteristics in cancer survivors: Results from pooled analyses of individual participant data of 26 RCTs.Kenkhuis MF, Doorenbos M, Mast IH, Aaronson NK, van Beurden M, Bohus M, Courneya KS, Daley AJ, Galvão DA, Goedendorp MM, van Harten WH, Hayes SC, Hiensch AE, Irwin ML, Kersten MJ, Knoop H, May AM, McConnachie A, van Mechelen W, Mutrie N, Newton RU, Nollet F, Oldenburg HS, Schmidt ME, Schmitz KH, Schulz KH, Sonke GS, Steindorf K, Stuiver MM, Taaffe DR, Thorsen L, Velthuis MJ, Wiskemann J, Mesters I, Ulrich CM, van Vulpen JK, Custers JAE, Buffart LM. Support Care Cancer. 2025 Jul 1; 2025 Jul 1. PMID: 40591016.
- Associations between colonization with Helicobacter pylori and risk of gastrointestinal tract cancers: An umbrella review of meta-analyses.Paiva Prudente T, Mezaiko E, Nunes Pereira Oliva H, Yamamoto-Silva FP, Santos de Freitas Silva B, Oliveira Oliva I, Risch H. Eur J Clin Invest. 2025 Jul; 2025 Jan 29. PMID: 39878420.
- Early NOTCH1 mutation is positively selected but epistatically suppresses evolution of later esophageal squamous-cell carcinoma drivers.Glasmacher KA, Mandell JD, Jackson M, Fisk N, Cannataro VL, Townsend JP. bioRxiv. 2025 Jun 25; 2025 Jun 25. PMID: 40667321.
- Mortality Outcomes for Survivors of Cancer With Food Insecurity in the US.Lin JC, Sun J, Yan R, Wang LS, McCarthy AM, Tong G, Aysola J. JAMA Health Forum. 2025 Jun 7; 2025 Jun 7. PMID: 40540285.
- Celecoxib as a potential treatment for hepatocellular carcinoma in populations exposed to high PFAS levels.Sun B, Zhao Y, Yang S, Li X, Li N, Wang Y, Han Q, Liu X, Tu Q, Zheng J, Zhang X. J Hazard Mater. 2025 Jun 5; 2025 Feb 13. PMID: 39955994.
- Competing Subclones and Fitness Diversity Shape Tumor Evolution Across Cancer Types.Chen H, Shu J, Mudappathi R, Li E, Wang P, Bergsagel L, Yang P, Sun Z, Zhao L, Shi C, Townsend JP, Maley C, Liu L. bioRxiv. 2025 Jun 3; 2025 Jun 3. PMID: 40502073.
- Biomarker-Specific Survival and Medication Cost for Patients With Non-Small Cell Lung Cancer.Tan J, Yang SC, Dinan MA, Chiang AC, Gross CP, Wang SY. JAMA Netw Open. 2025 Jun 2; 2025 Jun 2. PMID: 40493365.
- Contribution of chronic conditions to mortality: Differences by race and ethnicity.Elman MR, Quiñones AR, McAvay GJ, Vander Wyk B, Nagel CL, Allore HG. Aging Health Res. 2025 Jun; 2025 Apr 23. PMID: 40575585.
- Psychosocial Experiences of African American Parents of Children With Cancer.Eche-Ugwu IJ, Aronowitz T, Broden EG, Merz A, White-Hammond GE, Umaretiya PJ, Bullock K, Brock K, Johnston EE, Wolfe J, Feraco AM. Pediatrics. 2025 Jun 1. PMID: 40398876.
- Twenty-five years without progress: The enduring challenge of soft tissue sarcomas.Hardy NJ, Frej KBH, Nkansah R, Olino K, Deshpande H, Ma X, Trent JC, Costa P. Cancer. 2025 Jun 1. PMID: 40396557.
- Adoption of Broad Genomic Profiling in Patients With Cancer.Wang X, Rothen J, Huang S, Long JB, Soulos PR, Goldberg SB, Mamtani R, Presley CJ, Kunst N, Ma S, Wang SY, Gross CP, Dinan MA. JAMA Oncol. 2025 Jun 1. PMID: 40244595.
- Developing a digital video to support lung cancer screening in diverse populations.Lindsay M, Odole IP, Belliveau O, Abujarad F, Gross CP, Richman IB. PEC Innov. 2025 Jun; 2025 Mar 17. PMID: 40212805.
- Off-Label Use of First-Line Immunotherapy for Metastatic Renal Cell Carcinoma.McManus HD, Long JB, Westvold SJ, Leapman MS, Hurwitz ME, Mitchell AP, Pollack CE, Gross CP, Dinan MA. Clin Genitourin Cancer. 2025 Jun; 2025 Mar 15. PMID: 40186898.
- A robust multiplex-DIA workflow profiles protein turnover regulations associated with cisplatin resistance and aneuploidy.Salovska B, Li W, Bernhardt OM, Germain PL, Wang Q, Gandhi T, Reiter L, Liu Y. Nat Commun. 2025 May 30; 2025 May 30. PMID: 40447611.
- Breast Cancer Diagnosis and Management in an Area of Protracted Conflict: A Case Series from Northwest Syria.Hamze M, Alawa J, Alahdab F, Al-Shemali A, Alhussein AN, Arab NMA, Galal B, Debel J, Jemo A, Khalil M, Chagpar A, Atassi B, Khoshnood K, Abbara A. Avicenna J Med. 2025 Jan; 2025 May 19. PMID: 40395698.
- Canonical amplifications and CDKN2A/B loss refine IDH1/2-mutant astrocytoma prognosis.Ghosh HS, Patel RV, Claus EB, Gonzalez Castro LN, Wen PY, Ligon KL, Meredith DM, Bi WL. Neuro Oncol. 2025 May 15. PMID: 39584448.
- Breastfeeding attributable fraction of triple negative breast cancer in the US.Chehayeb RJ, Odzer N, Albany RA, Ferrucci L, Sarpong D, Perez-Escamilla R, Lewis JB, Phipps AI, Meisner A, Pusztai L. NPJ Breast Cancer. 2025 May 7; 2025 May 7. PMID: 40328734.
- Accelerated Aging in Cancer and Cancer Treatment: Current Status of Biomarkers.Abraham S, Parekh J, Lee S, Afrin H, Rozenblit M, Blenman KRM, Perry RJ, Ferrucci LM, Liu J, Irwin ML, Lustberg M. Cancer Med. 2025 May. PMID: 40322791.
- Sex-specific effects of exogenous asparagine on colorectal tumor growth, 17β-estradiol levels, and aromatase.Aladelokun O, Benitez K, Wang Y, Jain A, Berardi D, Maroun G, Shen X, Roper J, Gibson J, Sumigray K, Khan SA, Johnson CH. Pharmacol Res. 2025 May; 2025 Apr 12. PMID: 40228761.
- Perinatal Exposures to Ambient Fine Particulate Matter and Outdoor Artificial Light at Night and Risk of Pediatric Papillary Thyroid Cancer.Deziel NC, Wang R, Warren JL, Dinauer C, Ogilvie J, Clark CJ, Zhong C, Wiemels JL, Morimoto L, Metayer C, Ma X. Environ Health Perspect. 2025 May; 2025 May 29. PMID: 40209106.
- Uncovering Structurally Differential Care: Pediatric Oncology Nurses' Perspectives Caring for African American Families.Eche-Ugwu IJ, Aronowitz T, Broden EG, Merz A, Vernadakis A, Bullock K, Wolfe J, Feraco AM. J Pain Symptom Manage. 2025 May; 2025 Feb 5. PMID: 39920978.
- Primary Tumors of the Brain and Central Nervous System in Adults and Children in Sub-Saharan Africa: Protocol for a Scoping Review.Al-Fikri AAB, Alhammadi M, Arum C, Kaur M, Del Biondo K, Bani I, Mudenda V, Vermund SH. JMIR Res Protoc. 2025 Apr 24; 2025 Apr 24. PMID: 40273436.
Centers and other resources
- Yale Cancer Center (YCC)The Center provides the best approaches for the prevention, detection, diagnosis, and treatment of cancer.
- Yale Center for Analytical Sciences (YCAS)YCAS collaborative team provides expertise in the design, conduct, and analysis of health and health care studies, methodological development, and education and training.
- Yale-Griffin Prevention Research Center (PRC)The PRC works with community partners to develop and implement community-based approaches to prevent and control chronic diseases such as heart disease, diabetes, and cancer.