Research & Publications
Dr. Peter J. Krause is Senior Research Scientist in the Department of Epidemiology and Public Health, Yale School of Public Health and Yale School of Medicine, New Haven, CT. He received his B.A. with honors in biology from Williams College and his M.D. from Tufts University School of Medicine. He completed his Pediatric internship and residency at Yale-New Haven Hospital and Stanford University Medical Center and his Pediatric Infectious Diseases training at the University of California Los Angeles (UCLA). He joined the faculty at the University of Connecticut in 1979 where he became Professor of Pediatrics and Chief of the Division of Pediatric Infectious Diseases. He moved back to Yale in 2008.
Dr. Krause carries out translational, epidemiological, and clinical research in the study of vector-borne disease. His primary focus has been on human babesiosis but he has also carried out research on two companion tick-borne infections, Lyme disease and relapsing fever caused by Borrelia miyamotoi. He is the author of more than 200 peer reviewed scientific publications, 2 books, and 35 book chapters. He has served on the Editorial Boards of the Journal of Clinical Microbiology and is on the Editorial Boards of Clinical Infectious Diseases, Clinical Microbiology Reviews, Plos Neglected Tropical Diseases, and Pathogens. He has served on several leadership committees of the Infectious Diseases Society of America (IDSA) and Connecticut Infectious Diseases Society. He recently served as Chair of the committee that wrote the Clinical Practice Guidelines for the Infectious Diseases Society of America's 2020 Guideline on Diagnosis and Management of Babesiosis. He also was selected as a Member of the committee that wrote the Infectious Diseases Society of America Clinical Practice Guidelines for the Prevention, Diagnosis, and Treatment of Lyme Disease. He has been cited in American Men and Women of Science, The Best Doctors in America, and Who’s Who in America. He is currently serving on the Health and Human Services Office of the Assistant Secretary of Health Tick Borne Disease Working Group 2021-2022.
Dr. Krause and his colleagues were the first to:
- Characterize the frequency and clinical outcome of human tick-borne disease coinfection
- Identify the long-term persistence of Babesia infection in people
- Perform an antibiotic treatment trial for human babesiosis
- Characterize persistent and relapsing babesiosis in immunocompromised hosts
- Develop a laboratory method for screening the blood supply for Babesia microti infection
- Discover human infection by the relapsing fever spirochete Borrelia miyamotoi
- Discover human infection by Borrelia miyamotoi in the United States (co-discoverers)
- Develop a Borrelia miyamotoi antibody assay
- Describe the epidemiology of Borrelia miyamotoi infection
- Provide evidence that Borrelia miyamotoi may be transmitted through blood transfusion
- They also have quantitated the risk of transmission of babesiosis and Lyme disease though blood transfusion and developed several antibody and molecular-based tests for the diagnosis of babesiosis and Borrelia miyamotoi.
Education & Training
- Research FellowUCLA (1979)
- ResidentStanford University Medical Center (1974)
- ResidentYale New Haven Hospital (1973)
- InternYale New Haven Hospital (1972)
- MDTufts University School of Medicine (1971)
- BAWilliams College (1967)
- Tick-borne Disease ResearchObihiro, Japan; Moscow, Russia; New Haven, United States 2010We have collaborated with Russian scientists to describe the first human cases of Borrelia miyamotoi relapsing fever infection. We are continuing research collaboration to better define the epidemiology, ecology, clinical manifestations, pathogenesis, diagnosis and treatment of this infection. We are working with Japanese scientists to develop improved laboratory testing for the diagnosis of babesiosis, another emerging tick-borne infection.
Honors & Recognition
|Chair, Committee on the Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA): 2020 Guideline on Diagnosis and Management of Babesiosis||Infectious Diseases Society of America (IDSA)||2021|
|Member, Committee on the Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease||Infectious Diseases Society of America (IDSA)||2020|
|Fellow, American Society of Tropical Medicine and Hygiene||2016|
|Member, Committee on Infectious Diseases Society of America Practice Guidelines for the Treatment of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis||2006|
|Member, Infectious Disease Society of America Practice Guidelines Committee,||1994, 1998|
|Clinical Microbiology Reviews||Editorial Board||2021 - Present|
|Clinical Infectious Diseases||Editorial Advisory Board||2020 - Present|
|Pathogens||Editorial Board||2019 - Present|
|Plos Neglected Tropical Diseases||Deputy Editor 2020-||2018 - Present|