Michaela Dinan, PhD
Professor of Epidemiology (Chronic Diseases)Cards
Additional Titles
Associate Cancer Center Director for Research Training and Education, Yale Cancer Center
Co-Director, Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, Yale School of Medicine
Co-Leader, Cancer Prevention and Control, Yale Cancer Center
Contact Info
Chronic Disease Epidemiology
PO Box 208034, 60 College St
New Haven, CT 06520
United States
Appointments
Additional Titles
Associate Cancer Center Director for Research Training and Education, Yale Cancer Center
Co-Director, Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, Yale School of Medicine
Co-Leader, Cancer Prevention and Control, Yale Cancer Center
Contact Info
Chronic Disease Epidemiology
PO Box 208034, 60 College St
New Haven, CT 06520
United States
Appointments
Additional Titles
Associate Cancer Center Director for Research Training and Education, Yale Cancer Center
Co-Director, Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, Yale School of Medicine
Co-Leader, Cancer Prevention and Control, Yale Cancer Center
Contact Info
Chronic Disease Epidemiology
PO Box 208034, 60 College St
New Haven, CT 06520
United States
Appointments
About
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Titles
Professor of Epidemiology (Chronic Diseases)
Associate Cancer Center Director for Research Training and Education, Yale Cancer Center; Co-Director, Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, Yale School of Medicine; Co-Leader, Cancer Prevention and Control, Yale Cancer Center
Biography
Dr. Michaela Dinan is a Professor of Epidemiology in the Yale School of Public Health, Associate Cancer Center Director for Cancer Research Training and Education at the Yale Cancer Center (YCC) as well as Co-Director of the Yale Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center. She is also co-leader of the YCC Cancer Prevention and Control Research Program. Dr. Dinan has extensive research expertise in leveraging existing real-world data sources as well as novel data linkages to examine oncology outcomes.
Dr. Dinan is a health services researcher by training and she specializes in using econometric and epidemiologic methodologies to analyze complex datasets. Specifically, Dr. Dinan's research examines advances in cancer care technologies, such as emerging treatments and diagnostics, and how these advances in technologies impact different cancer outcomes and experiences such as access, quality of care, cost of care, and health disparities.
Dr. Dinan has led studies funded by the National Institutes of Health, the American Cancer Society, and the Agency for Healthcare Research and Quality. She is currently MPI of an NCI-funded R01 study examining broad genomic profiling in patients with lung cancer to determine how testing and test results impact treatment, survival, and costs of care. Dr. Dinan is also leading a study funded by the ACS to develop and validate risk prediction algorithms to inform efficient and high-quality care for long-term cancer survivors.
In 2021, Dr. Dinan led the first linkage of the Medicare claims data to physical tumor specimens and cancer registry data. This proof-of-concept study was the first to demonstrate the ability to combine the detailed clinicopathologic data from the SEER Registry, the longitudinal follow-up provided by the Medicare claims data, with genomic sequence data obtained from the physical tumor specimen all into one dataset. Dr. Dinan is the PI of an ACS Research Scholar Grant building on this novel data linkage to determine the molecular etiology of aggressive screening-detected breast cancers.
Appointments
Chronic Disease Epidemiology
ProfessorPrimaryMedical Oncology and Hematology
Associate Professor on TermSecondary
Other Departments & Organizations
- Cancer Prevention and Control
- Chronic Disease Epidemiology
- COPPER Center
- Medical Oncology and Hematology
- Public Health Data Science and Data Equity
- Yale Cancer Center
- Yale School of Public Health
- YCC Collaborative Excellence
Education & Training
- PhD
- University of North Carolina, Health Policy and Management (2011)
Research
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Overview
Dr. Dinan has extensive research expertise in leveraging existing real-world data sources as well as novel data linkages to examine oncology outcomes. She is a health services researcher with training in econometric and epidemiologic methodologies to analyze complex datasets. Specifically, Dr. Dinan's research involves issues related to access and quality of care, health disparities, and cost of care for cancer patients.
Medical Research Interests
Public Health Interests
ORCID
0000-0003-4849-4743
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Cary P Gross, MD
Michael S. Leapman, MD, MHS
Sarah Westvold, MPH
Shi-Yi Wang, MD, PhD
Timothy Robinson, MD, PhD
Ira Leeds, MD, FACS, FASCRS
Breast Neoplasms
Carcinoma, Renal Cell
Risk Assessment
Cancer Survivors
Costs and Cost Analysis
Chronic Disease
Publications
2025
Cardiovascular risk in long-term survivors of breast, prostate, colon, and rectal cancer
Westvold S, Long J, Fan J, Kc M, Hyslop T, Conlin K, Jacobson S, Silber A, Wang S, Leapman M, Leeds I, Spees L, Wheeler S, Gross C, Oeffinger K, Dinan M. Cardiovascular risk in long-term survivors of breast, prostate, colon, and rectal cancer. Journal Of The National Cancer Institute 2025, djaf243. PMID: 41069232, DOI: 10.1093/jnci/djaf243.Peer-Reviewed Original ResearchThis study investigates cardiovascular risk in older long-term cancer survivors, showing non-cancer factors, rather than cancer-specific ones, predict late-onset cardiovascular disease.Digital breast tomosynthesis and breast cancer detection in older women: Smaller tumors and more invasive lobular carcinomas.
Huang S, Westvold S, Soulos P, Winer E, Lewin J, Lustberg M, Zhan H, Richman I, Robinson T, Dinan M. Digital breast tomosynthesis and breast cancer detection in older women: Smaller tumors and more invasive lobular carcinomas. JCO Oncology Practice 2025, 21: 285-285. DOI: 10.1200/op.2025.21.10_suppl.285.Peer-Reviewed Original ResearchConceptsInvasive lobular carcinomaDigital breast tomosynthesisOlder womenBreast cancer detectionDigital mammographyLobular carcinomaCohort study of womenScreen-detected casesStudy of womenClaims-based algorithmER+/HER2- breast cancerBreast tomosynthesisTrial of womenCancer detectionScreening modalitiesPrimary exposureBreast cancerWomenEarly detectionCarcinomaTumorBreastTomosynthesisMammographyOpioid prescribing trends and pain scores among adult patients with cancer in a large health system
Baum L, Soulos P, Kc M, Jeffery M, Ruddy K, Lerro C, Lee H, Graham D, Rivera D, Liberatore M, Leapman M, Jairam V, Dinan M, Gross C, Park H. Opioid prescribing trends and pain scores among adult patients with cancer in a large health system. Cancer 2025, 131: e70027. PMID: 40977160, PMCID: PMC12451255, DOI: 10.1002/cncr.70027.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsOpioid prescribingMetastatic cancerNo painHealth systemPain scoresWidespread policy changeOpioid-naive adultsNewly diagnosed cancerOpioid-related harmsOpioid prescribing trendsPain managementOpioid prescriptionsRetrospective studyAdult patientsClinical strataPrescribingPrescribing trendsSurgical patientsLogistic regressionOpioidPainPatientsCancerStewardship policiesPolicy changesTreatment exposure-based risk-stratification for care of survivors of childhood cancer: a report from the childhood cancer survivor study
Dinan M, Stratton K, Leisenring W, Yasui Y, Chow E, Tonorezos E, Moskowitz C, Yeh J, Noyd D, Armstrong G, Oeffinger K. Treatment exposure-based risk-stratification for care of survivors of childhood cancer: a report from the childhood cancer survivor study. Journal Of The National Cancer Institute 2025, djaf268. PMID: 40971674, DOI: 10.1093/jnci/djaf268.Peer-Reviewed Original ResearchCitationsAltmetricConceptsChildhood Cancer Survivor StudyChronic health conditionsHealth conditionsFive-year survivorsCancer survivorsSurvivor StudyChronic conditionsFive-year survivors of childhood cancerNon-Hispanic white survivorsManagement of childhood cancer survivorsLong-term cancer survivorsSurvivors of childhood cancerChildhood cancer survivorsHigh-risk survivorsSevere chronic conditionsCox proportional hazards modelsSurvivorship clinicRisk of late morbidityWhite survivorsProportional hazards modelHealth careHealth-relatedChildhood cancerHigh-risk groupDiverse populationsArea Level Social Deprivation and Use of Prostate MRI Before Prostate Biopsy Among Commercial Insurance Beneficiaries
Smani S, Wang R, Zhou X, Sprenkle P, Kim I, Dinan M, Gross C, Ma X, Leapman M. Area Level Social Deprivation and Use of Prostate MRI Before Prostate Biopsy Among Commercial Insurance Beneficiaries. Urology 2025 PMID: 40759400, DOI: 10.1016/j.urology.2025.07.070.Peer-Reviewed Original ResearchConceptsPre-biopsy magnetic resonance imagingProstate magnetic resonance imagingMagnetic resonance imagingMagnetic resonance imaging useProstate biopsySocial deprivation indexArea-level measuresDynamic cohort studyMRI useMeasure of area-level deprivationSocioeconomic statusArea-level social deprivationArea-level measures of socioeconomic statusMeasures of socioeconomic statusStrata of socioeconomic statusArea-level deprivationCommercial insurance beneficiariesComposite measureBiopsyProstateNon-metropolitan areasDeprivation indexRural/urban statusResonance imagingSociodemographic factorsMachine Learning Risk Stratification for Older Breast Cancer Survivors: Clinical Care Implications
Wheeler S, Rotter J, Spees L, Biddell C, Trogdon J, Alfano C, Mayer D, Dinan M, Nekhlyudov L, Birken S. Machine Learning Risk Stratification for Older Breast Cancer Survivors: Clinical Care Implications. Health Services Research 2025, e70005. PMID: 40671264, DOI: 10.1111/1475-6773.70005.Peer-Reviewed Original ResearchCitationsConceptsBreast cancer survivorsAdverse health outcomesCancer survivorsHealth outcomesCancer-specific deathOlder breast cancer survivorsClinical care implicationsRisk prediction algorithmsAdverse outcomesHigh riskSEER-CAHPSRisk of all-cause deathPrimary careSurvivorship outcomesClinical risk prediction algorithmsCare implicationsClaims dataAll-cause deathCohen's kappaEnd ResultsSurvivorsCancer recurrenceFollow-up periodLow riskCareBiomarker-Specific Survival and Medication Cost for Patients With Non–Small Cell Lung Cancer
Tan J, Yang S, Dinan M, Chiang A, Gross C, Wang S. Biomarker-Specific Survival and Medication Cost for Patients With Non–Small Cell Lung Cancer. JAMA Network Open 2025, 8: e2514519. PMID: 40493365, PMCID: PMC12152704, DOI: 10.1001/jamanetworkopen.2025.14519.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsAdvanced non-small cell lung cancerNon-small cell lung cancerEGFR variationPD-L1ALK rearrangementCell lung cancerDriver alterationsMedical costsLung cancerCohort studyProgrammed cell death 1 ligand 1Cell death 1 ligand 1Biomarker statusMedian overall survivalRetrospective cohort studyLower medical costsOverall survivalTargeted therapyNon-smallPatient cohortMonthly medical costsFollow-upStudy cohortBiomarker testingAssociated with higher costsAdoption of Broad Genomic Profiling in Patients With Cancer
Wang X, Rothen J, Huang S, Long J, Soulos P, Goldberg S, Mamtani R, Presley C, Kunst N, Ma S, Wang S, Gross C, Dinan M. Adoption of Broad Genomic Profiling in Patients With Cancer. JAMA Oncology 2025, 11: 666-668. PMID: 40244595, PMCID: PMC12006912, DOI: 10.1001/jamaoncol.2025.0499.Peer-Reviewed Original ResearchAltmetricFactors associated with decreased treatment intensity in patients with metastatic colon cancer: A real world analysis.
Forman R, Wang R, Yasin F, Kwaramba T, Lacy J, Ma X, Dinan M. Factors associated with decreased treatment intensity in patients with metastatic colon cancer: A real world analysis. Journal Of Clinical Oncology 2025, 43: 11168-11168. DOI: 10.1200/jco.2025.43.16_suppl.11168.Peer-Reviewed Original ResearchConceptsMetastatic colon cancerNon-intensive therapyNational Comprehensive Cancer NetworkPoor performance statusIntensive therapyFlatiron Health electronic health record-derived deidentified databaseColon cancerIntensive first-line therapyUndertreatment of older patientsNational Comprehensive Cancer Network guidelinesOdds ratioAssociated with treatment choiceFirst-line therapyAssociated with female sexComprehensive Cancer NetworkRetrospective cohort studyYear of diagnosisShorter overall survivalNon-frail patientsOlder ageNon-frailMultivariate logistic regressionEstimate odds ratiosAssociated with receiptTreatment intensityRisk and predictors of late second primary malignancies in long-term breast, prostate, colon, and rectal cancer survivors.
Kwaramba T, Westvold S, Long J, Hyslop T, Silber A, Lustberg M, Wang S, Leapman M, Leeds I, Cecchini M, Spees L, Wheeler S, Gross C, Dinan M. Risk and predictors of late second primary malignancies in long-term breast, prostate, colon, and rectal cancer survivors. Journal Of Clinical Oncology 2025, 43: 1642-1642. DOI: 10.1200/jco.2025.43.16_suppl.1642.Peer-Reviewed Original ResearchConceptsSurvivors of breastRectal cancer survivorsCancer survivorsYears post-diagnosisPost-diagnosisOlder survivorsScreen-detectedSEER-MedicareLong-term cancer survivorsNon-screened cancersLong-term breastStage I-III cancerProstate cancer survivorsIndex cancer diagnosisContinuous Medicare Parts ASEER-Medicare dataModifiable risk factorsMedicare Part ADiagnosis of SPMSurvivorship careSEER-Medicare databaseSurvivorship cohortScreening guidelinesAssociated with shorter timeIndex cancer
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News
- November 17, 2025Source: MedPage Today
Here's what's driving late heart events in older cancer survivors
- October 07, 2025
Multi-Day Cancer Symposium Lays Groundwork for Research Collaboration
- September 22, 2025
Yale Study Finds Reduced Opioid Prescribing for Some Patients with Cancer
- August 08, 2025
Yale Cancer Center’s CRTEC Program Launches Future Deaf Scientists Internship
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Chronic Disease Epidemiology
PO Box 208034, 60 College St
New Haven, CT 06520
United States
Locations
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Academic Office
60 College Street
New Haven, CT 06510