Lauren Pischel, MD, MSc
Assistant Professor of Medicine (Infectious Diseases)DownloadHi-Res Photo
Cards
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Contact Info
About
Copy Link
Titles
Assistant Professor of Medicine (Infectious Diseases)
Affiliated Faculty, Yale Institute for Global Health
Biography
Dr. Lauren Pischel obtained her undergraduate degree in biology at Brown University and worked in the lab of Dr. Jake Kurtis on the development of a pediatric malaria vaccine. She obtained her MD at Stanford where she conducted research with Dr. Julie Parsonnet on the impact of an antimicrobial triclosan on the human microbiome. She then completed her internal medicine residency at Yale where she was awarded the primary care award for the Fair Haven Community Health Center. She subsequently pursued her fellowship in infectious diseases at Yale and her Master of Science in the epidemiology of infectious diseases at the Yale School of Public Health under the mentorship of Saad Omer and Inci Yildirim. Her research interests include the epidemiology and household transmission of COVID-19 and influenza as well estimating vaccine effectiveness using real-world data and the epidemiology emerging infectious diseases.
Last Updated on April 10, 2025.
Departments & Organizations
Education & Training
- MSc
- Yale, Public Health- Epidmiology of Infectious Diseases (2022)
- MD
- Stanford School of Medicine (2016)
- ScB
- Brown University, Biology (2011)
Research
Copy Link
Overview
Public Health Interests
Global Health; Climate Change; Emerging Infectious Diseases; Vaccines
ORCID
0000-0002-7697-0084
Research at a Glance
Yale Co-Authors
Frequent collaborators of Lauren Pischel's published research.
Publications Timeline
A big-picture view of Lauren Pischel's research output by year.
Richard A Martinello, MD
Albert Ko, MD
George Goshua, MD, MSc, FACP
Carolina Lucas, PhD
Justin Belsky, MD, MPH
Lydia Aoun-Barakat, MD
33Publications
513Citations
Publications
2025
The Impact of Orthopoxvirus Vaccination and Mpox Infection on Cross-Protective Immunity 2402
Crandell J, Monteiro V, Pischel L, Fang Z, Conde L, Zhong Y, Lawres L, Breban M, Vogels C, Grubaugh N, Aoun-Barakat L, Grifoni A, Sette A, Chen S, Yildirim I, Vale A, Omer S, Lucas C. The Impact of Orthopoxvirus Vaccination and Mpox Infection on Cross-Protective Immunity 2402. The Journal Of Immunology 2025, 214 DOI: 10.1093/jimmun/vkaf283.326.Peer-Reviewed Original ResearchConceptsT cell responsesComplement-mediated neutralizationMpox virusT cellsViral immunologyCross-neutralizing responsesT cell memoryCross-reactive T cell memoryCross-neutralizing antibodiesCowpox virusCross-protective immunityVaccine recipientsImmunological memoryMucosal responsesAntibody effector functionsAntigenic distanceEffector functionsCross-reactive memoryVaccine efficacyCross-neutralizationJYNNEOSVaccineAntibodiesVACVCross-protectionHuman monoclonal antibodies targeting A35 protect from death against mpox 2296
Fantin R, Civljak A, Ignacio M, Park S, Crandell J, Monteiro V, Earl P, Cohn H, Bozarth B, Cotter C, Nardulli J, Burkhardt M, Srivastava K, Altman D, Lugo L, Bajic G, Pischel L, Yildirim I, Omer S, Simon V, Lucas C, Moss B, Coelho C. Human monoclonal antibodies targeting A35 protect from death against mpox 2296. The Journal Of Immunology 2025, 214 DOI: 10.1093/jimmun/vkaf283.231.Peer-Reviewed Original ResearchConceptsMonkeypox virusVaccinia virusWorld Health OrganizationAntibody-based therapiesHuman monoclonal antibodyIn vivo neutralizationBALB/c mouse modelEfficacy in vitroCross-protective immunitySafety profileNon-endemic regionsGlobal health threatMouse modelNational InstituteVaccine developmentMonoclonal antibodiesProphylactic measuresProtection assayPublic health emergencyIn vitroViral attachmentMAbVaccineHealth OrganizationHealth threatComparable Outcomes in Suspected Septic Shock: A Retrospective Study of Emergency Department Patients With and Without Bacteremia
Belsky J, Wira C, Fryman A, He Z, Boccio E, Haimovich A, Jacob V, Pischel L. Comparable Outcomes in Suspected Septic Shock: A Retrospective Study of Emergency Department Patients With and Without Bacteremia. Journal Of Emergency Medicine 2025, 79: 349-358. PMID: 41175539, DOI: 10.1016/j.jemermed.2025.08.039.Peer-Reviewed Original ResearchAltmetricConceptsEmergency departmentHospital outcomesIntensive care unit lengthPresence of bacteremiaLength of stayED variablesSeptic shockBlood culturesHospital mortalityUrban academic centerRetrospective studyAdult patientsHospital lengthEmergency department patientsIntensive care unit length of stayUnit length of stayGram-negative bacteremiaHospital length of stayInitial blood cultureLogistic regression analysisAssociated with bacteremiaPatient encountersRetrospective observational analysisDepartment patientsSecondary aimBarriers and Facilitators to COVID19 Vaccination Access Among Older Adults: A Comprehensive Needs Assessment for Vaccination Strategies
Lee J, Trumpler J, Roberts S, Pischel L, Martinello R. Barriers and Facilitators to COVID19 Vaccination Access Among Older Adults: A Comprehensive Needs Assessment for Vaccination Strategies. Antimicrobial Stewardship & Healthcare Epidemiology 2025, 5: s82-s82. PMCID: PMC12461516, DOI: 10.1017/ash.2025.302.Peer-Reviewed Original ResearchConceptsPlan-Do-Study-ActOlder adultsSemi-structured interviewsHealthcare leadersIterative Plan-Do-Study-ActNeeds assessmentSystem-specific barriersPrimary care sitesHealth care providersInsufficient financial incentivesQuality improvement effortsHigh-impact interventionsComprehensive needs assessmentHealth care systemComplex vaccination scheduleBarriers to COVID-19 vaccinationAmbulatory locationsOn-site vaccinationPrimary careClinical partnershipsCare sitesEducation sessionsCare providersHealthcare visitsHealthcare professionalsSocial mixing patterns of United States healthcare personnel at a quaternary health center: a prospective observational study
Pischel L, Aguolu O, Ahmed N, Campbell M, Borg R, Duckwall C, Willebrand K, Zaleski A, Paintsil E, Muenker M, Malik A, Kiti M, Warren J, Jenness S, Lopman B, Belsky J, Martinello R, Yildirim I, Ko A, Omer S. Social mixing patterns of United States healthcare personnel at a quaternary health center: a prospective observational study. Infection Control And Hospital Epidemiology 2025, 46: 289-297. PMID: 39880795, PMCID: PMC11883655, DOI: 10.1017/ice.2024.234.Peer-Reviewed Original ResearchAltmetricConceptsHealthcare personnelUnited States healthcare systemStates healthcare systemCOVID-19 pandemicNurse aidesContact diariesHealth centersHealthcare systemWorking-age populationImaging technologistsLow-contact groupNursesRegression modelsPandemic responseWork environmentSocial contactCOVID-19Job typeThree-hundredWorking daysDiaryParticipantsPersonnelInfectious disease transmissionContact groupP-271. Contact Patterns of United States Health Care Workers at Quaternary Health Center: Stability of contacts during the post-pandemic era
Pischel L, Aguolu O, Ahmed N, Campbell M, Borg R, Duckwall C, Willebrand K, Paintsil E, Muenker M, Malik A, Kiti M, Jenness S, Lopman B, Belsky J, Martinello R, Yildirim I, Ko A, Omer S. P-271. Contact Patterns of United States Health Care Workers at Quaternary Health Center: Stability of contacts during the post-pandemic era. Open Forum Infectious Diseases 2025, 12: ofae631.475. PMCID: PMC11777566, DOI: 10.1093/ofid/ofae631.475.Peer-Reviewed Original ResearchCitationsConceptsHealth care workersHealth care worker participationCare workersUnited States health care systemStates health care systemAge rangeHealth care systemHealth care workers' contactsLinear regressionHealth centersCare systemChi-square testCOVID-19 pandemic responseContact diariesEpidemiological researchParticipants' jobsWorking-age populationWorking ageConfidence intervalsImaging technologistsParticipantsPandemic responseSocial workersWork environmentWorking days
2024
Comprehensive profiling of social mixing patterns in resource poor countries: A mixed methods research protocol
Aguolu O, Kiti M, Nelson K, Liu C, Sundaram M, Gramacho S, Jenness S, Melegaro A, Sacoor C, Bardaji A, Macicame I, Jose A, Cavele N, Amosse F, Uamba M, Jamisse E, Tchavana C, Briones H, Jarquín C, Ajsivinac M, Pischel L, Ahmed N, Mohan V, Srinivasan R, Samuel P, John G, Ellington K, Joaquim O, Zelaya A, Kim S, Chen H, Kazi M, Malik F, Yildirim I, Lopman B, Omer S. Comprehensive profiling of social mixing patterns in resource poor countries: A mixed methods research protocol. PLOS ONE 2024, 19: e0301638. PMID: 38913670, PMCID: PMC11195963, DOI: 10.1371/journal.pone.0301638.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsLow-and-middle-income countriesData collection toolHousehold membersBurden of communicable diseasesCollection toolLow-and-middle-incomeDisease prevention strategiesInteraction dataPatterns of social mixingSocial mixingParameterizing mathematical modelsResource poor countriesPoor countriesCognitive interviewsLMIC populationsDisproportionate burdenQuantitative dataCommunicable diseasesStudy sitesPrevention strategiesContact diariesGroup discussionsStudy proceduresStudy toolDisease modelsVaccine effectiveness of 3rd generation mpox vaccines against mpox and disease severity: A systematic review and meta-analysis
Pischel L, Martini B, Yu N, Cacesse D, Tracy M, Kharbanda K, Ahmed N, Patel K, Grimshaw A, Malik A, Goshua G, Omer S. Vaccine effectiveness of 3rd generation mpox vaccines against mpox and disease severity: A systematic review and meta-analysis. Vaccine 2024, 42: 126053. PMID: 38906763, DOI: 10.1016/j.vaccine.2024.06.021.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPost-exposure prophylaxisMVA-BNVaccine effectivenessMeta-analysisTime of administrationNewcastle-Ottawa ScaleRisk of publication biasMeasuring vaccine efficacyImmortal time biasImmunogenicity studiesNewcastle-OttawaWeb of ScienceVaccine efficacyAnimal studiesEgger's testDisease severityFunnel plotPrimary searchDosePublication biasStudy qualityVaccineSystematic reviewVaccination timingMpox outbreakCharacterizing healthcare personnel attitudes toward receipt of a voluntary bivalent COVID-19 booster vaccine during a COVID-19 outbreak at a behavioral health hospital in Connecticut
Roberts S, Willebrand K, Fredrick J, Pischel L, Patel K, Murray T, Martinello R. Characterizing healthcare personnel attitudes toward receipt of a voluntary bivalent COVID-19 booster vaccine during a COVID-19 outbreak at a behavioral health hospital in Connecticut. Antimicrobial Stewardship & Healthcare Epidemiology 2024, 4: e87. PMID: 38774120, PMCID: PMC11106727, DOI: 10.1017/ash.2024.78.Peer-Reviewed Original ResearchCitationsAltmetric
2023
Characterizing healthcare worker attitudes toward the bivalent COVID-19 booster
Willebrand K, Fredrick J, Pischel L, Patel K, Roberts S, Murray T, Martinello R. Characterizing healthcare worker attitudes toward the bivalent COVID-19 booster. Antimicrobial Stewardship & Healthcare Epidemiology 2023, 3: s56-s57. PMCID: PMC10594485, DOI: 10.1017/ash.2023.300.Peer-Reviewed Original ResearchConceptsBooster doseBehavioral health unitHealthcare workersHealth unitsCOVID-19COVID-19 outbreakInpatient behavioral health unitFirst booster dosePrimary vaccination seriesCOVID-19 vaccinationCOVID-19 exposureBehavioral health settingsMonovalent vaccinationVaccination seriesBooster dosesBooster vaccineComplete responsePrevious vaccinationVaccine uptakeHealth HospitalGeneral populationSide effectsPsychiatric hospitalHealth settingsDemographic data
Academic Achievements & Community Involvement
Copy Link
Honors
honor Janeway Society Member
10/10/2024Yale School of Medicine Award
Clinical Care
Copy Link
Board Certifications
Infectious Disease
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2021
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2019
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileNews
Copy Link
News
- December 17, 2025Source: Yahoo Lifestyle
The One Thing That Reliably Kills Norovirus and How to Keep it From Spreading in Your Home
- December 25, 2024Source: SELF
Walking Pneumonia Is on the Rise. Here Are the Symptoms to Look Out For
- July 27, 2022
New Appointments & Promotions Within Department of Internal Medicine
- December 02, 2020
Infectious Disease Fellowship Supports Doctor’s Research
Get In Touch
Copy Link