Gary Ginsberg, PhD
Professor Adjunct of Epidemiology (Environmental Health)Cards
Additional Titles
Clinical Professor, Environmental Health Sciences
Contact Info
About
Titles
Professor Adjunct of Epidemiology (Environmental Health)
Clinical Professor, Environmental Health SciencesBiography
Dr. Ginsberg is the director of the Center for Environmental Health for the New York State Dept of Health and has a Clinical Professor appointment at the Yale School of Public Health. He serves on a number of national committees including US EPA’s Science Advisory Board (2008-present) and the National Academy of Sciences (Biomonitoring committee 2004-2006; USEPA Risk Methods committee which produced Science and Decisions, 2006-2008; Inorganic Arsenic Risk Assessment committee, 2012-2015, Emerging Science committee 2016-present). He also served on USEPA’s Children’s Health Protection Advisory Committee (2004-2009) and has been an external reviewer on a number of USEPA IRIS documents. Dr. Ginsberg has been called on by other federal agencies to provide reviews including OSHA (silica workplace standard), CPSC (cadmium in children’s jewelry) and FDA (dental amalgam). His risk assessments on fish contaminants, synthetic turf fields, acrylamide, cadmium, and assessments pertaining to risks in children and those with genetic polymorphisms have been published in peer review journals. Dr. Ginsberg co-authored a book for the lay public called “What’s Toxic What’s Not” (Berkeley Books, 2006).
Appointments
Environmental Health Sciences
Professor AdjunctPrimary
Other Departments & Organizations
Education & Training
- PhD
- University of Connecticut (1986)
Research
Overview
Identification of hazardous chemicals in consumer products
Evaluation of children’s risks from house dust and indoor air
Construction of population vulnerability distributions to assess inter-individual variability in toxicant response
Comparing the risks and benefits of fish consumption
Research at a Glance
Publications Timeline
Publications
2014
Methylmercury-Induced Inhibition of Paraoxonase-1 (PON1)—Implications for Cardiovascular Risk
Ginsberg G, Sonawane B, Nath R, Lewandowski P. Methylmercury-Induced Inhibition of Paraoxonase-1 (PON1)—Implications for Cardiovascular Risk. Journal Of Toxicology And Environmental Health Part A 2014, 77: 1004-1023. PMID: 25072822, DOI: 10.1080/15287394.2014.919837.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAnimalsAntioxidantsAryldialkylphosphataseCarboxylic Ester HydrolasesCardiovascular DiseasesDisease Models, AnimalDose-Response Relationship, DrugFatty Acids, Omega-3FishesFood ContaminationHumansLipid MetabolismMeatMethylmercury CompoundsMiceReactive Oxygen SpeciesRisk AssessmentRisk FactorsConceptsCardiovascular riskParaoxonase 1PON1 activityDoses of MeHgAcute cardiovascular eventsSerum PON1 activityHigh-density lipoproteinCardiovascular eventsBlood lipidsMeHg doseCardiovascular healthFish-eating populationsCardiovascular diseaseCardioprotective factorPON1 levelsVascular endotheliumDisease processEpidemiology studiesClinical biomarkersPopulation riskBiochemical effectsAntioxidant defenseRiskFish consumptionDisease biomarkers
2012
Cadmium Risk Assessment in Relation to Background Risk of Chronic Kidney Disease
Ginsberg GL. Cadmium Risk Assessment in Relation to Background Risk of Chronic Kidney Disease. Journal Of Toxicology And Environmental Health Part A 2012, 75: 374-390. PMID: 22524593, DOI: 10.1080/15287394.2012.670895.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsChronic kidney diseaseKidney diseaseU.S. Environmental Protection Agency reference dosesStage 3 chronic kidney diseaseNoncancer effectsPopulation riskCurrent dietary exposureMinimum risk levelLower Cd doseCKD riskDisease Registry's Minimum Risk LevelDaily doseLow doseChronic daily doseSwedish womenDietary exposureLeft shiftAdverse effectsCd doseDiseaseCadmium risk assessmentDoseReference dosesDose responseGFR
2011
Synthetic Turf Field Investigation in Connecticut
Simcox NJ, Bracker A, Ginsberg G, Toal B, Golembiewski B, Kurland T, Hedman C. Synthetic Turf Field Investigation in Connecticut. Journal Of Toxicology And Environmental Health Part A 2011, 74: 1133-1149. PMID: 21797768, DOI: 10.1080/15287394.2011.586941.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAir PollutantsAir Pollution, IndoorAltitudeBenzothiazolesButylated HydroxytolueneConnecticutElastomersFacility Design and ConstructionLeadNaphthalenesNitrosaminesParticulate MatterPlay and PlaythingsPoaceaePublic FacilitiesPublic Health PracticeRecyclingSeasonsSports EquipmentVolatile Organic CompoundsConceptsVolatile organic compoundsOrganic compoundsCertain volatile organic compoundsStationary air samplesRubber fieldBenzothiazoleStationary concentrationVOC concentrationsNatural grass fieldCompoundsAir monitoringChemicalsAir samplesPublic health targetsBulk samplesAir samplingPersonal air samplingBackground samplesReporting levelsBenzothiazole Toxicity Assessment in Support of Synthetic Turf Field Human Health Risk Assessment
Ginsberg G, Toal B, Kurland T. Benzothiazole Toxicity Assessment in Support of Synthetic Turf Field Human Health Risk Assessment. Journal Of Toxicology And Environmental Health Part A 2011, 74: 1175-1183. PMID: 21797770, DOI: 10.1080/15287394.2011.586943.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHealth risk assessmentSynthetic turf fieldsHuman health risk assessmentSubchronic dietary studyHuman bladder cancerOral slope factorBladder cancerInhalation exposureRoute extrapolationRespiratory irritantsRisk assessmentDermal sensitizerMetabolic activationEffect levelRodent carcinogensChemical exposureToxicology databaseCarcinogenic potentialAcute toxicityGenetic toxicityDietary studiesUnit riskTurf fieldsRiskSlope factorHuman Health Risk Assessment of Synthetic Turf Fields Based Upon Investigation of Five Fields in Connecticut
Ginsberg G, Toal B, Simcox N, Bracker A, Golembiewski B, Kurland T, Hedman C. Human Health Risk Assessment of Synthetic Turf Fields Based Upon Investigation of Five Fields in Connecticut. Journal Of Toxicology And Environmental Health Part A 2011, 74: 1150-1174. PMID: 21797769, DOI: 10.1080/15287394.2011.586942.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdultAge FactorsAir PollutantsAir Pollution, IndoorAthletesBenzothiazolesCarcinogens, EnvironmentalChildConnecticutElastomersEnvironmental ExposureFacility Design and ConstructionGuidelines as TopicHumansNeoplasmsPlay and PlaythingsPublic FacilitiesRecyclingRespiratory RateRisk AssessmentRisk FactorsSeasonsSports EquipmentConceptsSynthetic turf fieldsGreater ventilationAdverse health risksAcute hazard indexInhalation rateAdequate ventilationSeparate risk assessmentHealth risk assessmentHuman health risk assessmentPossible exposurePotential concernTurf fieldsRisk assessmentHigh exposureExposure concentrationsHealth risksBreathing zoneHazard indexVentilationPersonal samplersExposureAdultsState of ConnecticutChildrenNew York CityDevelopment and evaluation of a harmonized physiologically based pharmacokinetic (PBPK) model for perchloroethylene toxicokinetics in mice, rats, and humans
Chiu WA, Ginsberg GL. Development and evaluation of a harmonized physiologically based pharmacokinetic (PBPK) model for perchloroethylene toxicokinetics in mice, rats, and humans. Toxicology And Applied Pharmacology 2011, 253: 203-234. PMID: 21466818, DOI: 10.1016/j.taap.2011.03.020.Peer-Reviewed Original ResearchCitationsAltmetricPolymorphism in the DNA repair enzyme XRCC1: Utility of current database and implications for human health risk assessment
Ginsberg G, Angle K, Guyton K, Sonawane B. Polymorphism in the DNA repair enzyme XRCC1: Utility of current database and implications for human health risk assessment. Mutation Research/Fundamental And Molecular Mechanisms Of Mutagenesis 2011, 727: 1-15. PMID: 21352951, DOI: 10.1016/j.mrrev.2011.02.001.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsBase excision repairDNA repairGene expressionRepair functionUpstream regulatory sequencesDNA damaging agentsHomozygous variantToxicodynamic responseXRCC1 levelsRegulatory sequencesBinding sequenceExcision repairDamaging agentsProtein structureBER genesDNA damageAllele frequenciesCurrent databasePolymorphismGenotype effectsArg399Gln variantPhenotypeGenetic polymorphismsXRCC1Environmental agents
2000
Development of a single-meal fish consumption advisory for methyl mercury.
Ginsberg G, Toal B. Development of a single-meal fish consumption advisory for methyl mercury. Risk Analysis 2000, 20: 41-7. PMID: 10795337, DOI: 10.1111/0272-4332.00004.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsFish consumption advisoriesMaternal hair concentrationsConsumption advisoriesMethyl mercuryHair concentrationsU.S. Environmental Protection Agency reference doseEnvironmental Protection Agency reference doseFish MeHg concentrationsMercury hair concentrationFish tissue concentrationsMeHg body burdenAcute exposure to MeHgContamination of fishExposure to MeHgFish sampling programSingle-meal scenariosMeHg concentrationsRfD levelFish concentrationsBody burdenFish consumptionReference doseMeHgSampling programSeasonal differences
Links & Media
News
- December 16, 2019
Threat of Toxic Chemicals Draws Scores of Experts to Yale School of Public Health
- March 13, 2018
Is it Safe? methylene chloride and N-methyl pyrrolidone
- October 25, 2017
Is it Safe?
- April 06, 2017
Is It Safe? Vaping