E. Jennifer Edelman, MD, MHS, BS
Professor of Medicine (General Medicine)Cards
About
Research
Publications
2025
Implementation facilitation improves readiness for emergency department-initiated buprenorphine to treat opioid use disorder
Strout T, Dziura J, Barrett T, Cowan E, Hawk K, Herring A, Manteuffel J, Martel S, Owens P, McCormack R, Perrone J, Fiellin D, D'Onofrio G, Edelman E. Implementation facilitation improves readiness for emergency department-initiated buprenorphine to treat opioid use disorder. Journal Of Substance Use And Addiction Treatment 2025, 209845. PMID: 41354305, DOI: 10.1016/j.josat.2025.209845.Peer-Reviewed Original ResearchImplementation facilitatorsEmergency department-initiated buprenorphineOpioid use disorderED readinessRandomized clinical trialsMedical directorsED medical directorsSite principal investigatorsUse disorderTreatment of opioid use disorderNursing supportAddress barriersLikert scale ratingsPost-enrollmentLinear regression modelsPre-enrollmentInsurance coverageTreatment availabilityClinical trialsRegression modelsFacilitationBuprenorphineReadinessTime pointsScale ratingsAlcohol-Related Hospitalizations From 2016 to 2022
Bernstein E, Wilson L, Kruse G, Edelman E, Herzig S, Anderson T. Alcohol-Related Hospitalizations From 2016 to 2022. JAMA Network Open 2025, 8: e2550589. PMCID: PMC12728657, DOI: 10.1001/jamanetworkopen.2025.50589.Peer-Reviewed Original ResearchAlcohol-related hospitalizationsCross-sectional studyDischarge diagnosis codesAlcohol use disorderLength of stayIn-Hospital MortalityDiagnosis codesPopulation-level alcohol consumptionAlcohol useUnhealthy alcohol useAlcohol-related diagnosesHealth care costsHealth care spendingMedical complicationsNational Inpatient SampleAnnual rateMain OutcomesCare costsCost of hospitalizationCare spendingAdministrative dataPrevention effortsAlcohol consumptionAlcohol use disorder treatmentUS trendsPsychosocial correlates of awareness of HIV pre-exposure prophylaxis (PrEP) among persons who inject drugs in Northeast Georgia
Haider M, Clinton S, Zaman J, Ahmed F, Mehra R, Arayasirikul S, McFarland W, Mirzazadeh A, Edelman E, Hansen N. Psychosocial correlates of awareness of HIV pre-exposure prophylaxis (PrEP) among persons who inject drugs in Northeast Georgia. AIDS Care 2025, ahead-of-print: 1-14. PMID: 41318110, DOI: 10.1080/09540121.2025.2592886.Peer-Reviewed Original ResearchSyringe service programsHIV pre-exposure prophylaxisPrEP awarenessPre-exposure prophylaxisPsychosocial correlatesAssociated with PrEP awarenessOdds of PrEP awarenessUptake of HIV pre-exposure prophylaxisHIV prevention continuumSexualized drug useInjected drugsHIV-negative PWIDPrEP informationHIV testingPrevention continuumHIV diagnosisHealth insurancePrEPPsychological stressDrug usePWIDPsychosocialHIVService programsNortheast GeorgiaPrevalence and Patient-Level Factors Associated with Common Antibiotic Allergy Labels Among Patients Undergoing Hematopoietic Stem Cell Transplants: A Cross-Sectional Study
Belmont A, Reynolds J, Stone C, Dziura J, Malinis M, Phillips E, Sarpong D, Seropian S, Edelman E. Prevalence and Patient-Level Factors Associated with Common Antibiotic Allergy Labels Among Patients Undergoing Hematopoietic Stem Cell Transplants: A Cross-Sectional Study. The Journal Of Allergy And Clinical Immunology In Practice 2025 PMID: 41161669, PMCID: PMC12753012, DOI: 10.1016/j.jaip.2025.10.016.Peer-Reviewed Original ResearchHepatology clinician readiness to provide addiction treatment in hepatology clinics: A mixed-methods formative evaluation
Haque L, Choi H, Justen M, Deng Y, Edelman E, Fiellin D. Hepatology clinician readiness to provide addiction treatment in hepatology clinics: A mixed-methods formative evaluation. Hepatology Communications 2025, 9: e0818. PMID: 41085538, PMCID: PMC12520222, DOI: 10.1097/hc9.0000000000000818.Peer-Reviewed Original ResearchConceptsHepatology clinicAUD treatmentAddiction treatmentMixed-methods formative evaluationTreatment of AUDUrban academic medical centerAcademic medical centerSemi-structured interviewsLiver diseaseHepatologyPractice patternsMedical CenterTobacco useClinicClinical toolOpioidImplementation science frameworkTreatmentPatientsFlexible care modelsAddictionCliniciansDisorder treatmentOUDMedicationVariation in initiation of medications for alcohol use disorder during alcohol withdrawal hospitalizations in a large health system: A retrospective cohort study
Bernstein E, Lebin J, Hoppe J, Clinton I, Gritz R, Kruse G, Edelman E. Variation in initiation of medications for alcohol use disorder during alcohol withdrawal hospitalizations in a large health system: A retrospective cohort study. Journal Of Hospital Medicine 2025 PMID: 41060248, DOI: 10.1002/jhm.70201.Peer-Reviewed Original ResearchRetrospective cohort studyHealth systemHospital sitesAlcohol use disorderElectronic health recordsAddiction consult servicesUse disorderOral naltrexoneInitiation of medicationHealth recordsInpatient administrationHospital factorsPharmacy dataUnmet opportunitiesCohort studyPatient factorsMultivariate linear modelHospitalHealthInjectable naltrexoneHigher RatesIndividual patientsPatientsNaltrexoneRandom effectsExercise Interventions Among Individuals With Co-occurring HIV And Unhealthy Substance Use: A Systematic Review
Mistler C, Allen W, Grimshaw A, Idiong C, Harsono D, Irwin M, Ash G, Pescatello L, Meyer J, Edelman E. Exercise Interventions Among Individuals With Co-occurring HIV And Unhealthy Substance Use: A Systematic Review. Medicine & Science In Sports & Exercise 2025, 57: 755-755. DOI: 10.1249/01.mss.0001161400.40878.dc.Peer-Reviewed Original ResearchAlcohol interventions for persons with HIV: Meta-analysis of randomized controlled trials using phosphatidylethanol and self-report
Hahn J, Kane J, Fatch R, Espinosa da Silva C, Emenyonu N, Scheffler A, Chirayil P, So-Armah K, Kahler C, Conroy A, Edelman E, Woolf-King S, Parry C, Kiene S, Chamie G, Muyindike W, Adong J, Go V, Cook R, Morojele N, Fiellin D, Santos G, Tahir P, Samet J, Krupitsky E, Allen I. Alcohol interventions for persons with HIV: Meta-analysis of randomized controlled trials using phosphatidylethanol and self-report. Drug And Alcohol Dependence 2025, 276: 112879. PMID: 40992009, DOI: 10.1016/j.drugalcdep.2025.112879.Peer-Reviewed Original ResearchRandomized Controlled TrialsUnhealthy alcohol useAlcohol interventionsSelf-ReportAlcohol useIndividual Participant Data Meta-AnalysisSystematic reviewIntervention RCTsParticipant data meta-analysisPrimary outcomeSelf-reported alcohol useRisk-of-bias assessmentMeta-analysisAlcohol intervention studyCertainty of evidenceData Meta-AnalysisRandom-effects modelMeta-analysis of randomized controlled trialsIPD-MAIntervention efficacyIntervention studiesControlled TrialsEffect sizeModerate riskIntervention253 Implementation Facilitation Improves Readiness for Buprenorphine Initiation in Opioid Use Disorder
Strout T, Dziura J, Barrett T, Cowan E, Hawk K, Herring A, Manteuffel J, McCormack R, Fiellin D, D'Onofrio G, Edelman E. 253 Implementation Facilitation Improves Readiness for Buprenorphine Initiation in Opioid Use Disorder. Annals Of Emergency Medicine 2025, 86: s109. DOI: 10.1016/j.annemergmed.2025.06.269.Peer-Reviewed Original ResearchMicrocosting implementation facilitation for emergency department-initiated buprenorphine for untreated opioid use disorder
Ryan D, Lu T, Edelman E, Hawk K, O'Connor P, Coupet E, Jalali A, Owens P, Fiellin D, D'Onofrio G, Murphy S. Microcosting implementation facilitation for emergency department-initiated buprenorphine for untreated opioid use disorder. The American Journal Of Emergency Medicine 2025, 98: 124-129. PMID: 40865260, PMCID: PMC12716430, DOI: 10.1016/j.ajem.2025.08.002.Peer-Reviewed Original ResearchED-initiated buprenorphineImplementation facilitatorsOpioid use disorderPre-implementationEvidence-based implementation strategiesUse disorderHealth system resourcesEmergency department-initiated buprenorphineMicrocosting analysisUntreated opioid use disorderDrug Abuse Treatment Cost Analysis ProgramPer-patient costsImplementation strategiesBuprenorphine programMicrocostingStudy dataFormative evaluationClinical settingReferralHealthFinancial costsMOUDBuprenorphineQuantitative dataFacilitation
Clinical Trials
Current Trials
Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE)
HIC ID2000030586RolePrincipal InvestigatorPrimary Completion Date02/28/2023Recruiting ParticipantsGenderBothAge18+ years
Academic Achievements & Community Involvement
Clinical Care
Overview
E. Jennifer Edelman, MD, MHS, specializes in HIV and addiction medicine. She provides patient care for HIV/AIDS and its associated complications, such as HIV-associated myopathy, dementia, and neurocognitive disorder.
In addition to her clinical work in HIV care, Dr. Edelman’s research examines substance use disorder treatment in HIV clinics, emergency department-initiated buprenorphine programs, and alcohol reduction interventions for people with HIV.
A recipient of the New England Society of General Internal Medicine Award for Excellence in Clinical Investigation and the Society of General Internal Medicine Lawrence Linn Award, her research has been supported by grants from the National Institutes of Health, the National Institute on Alcohol Abuse and Alcoholism, and the National Cancer Institute.
Dr. Edelman is a professor of medicine at Yale School of Medicine.
Clinical Specialties
Internal Medicine; Addiction Medicine; HIV & AIDs Medicine
Fact Sheets
Human Immunodeficiency Virus (HIV)
Learn More on Yale MedicineOpioid Use Disorder
Learn More on Yale MedicineStimulant Use Disorder
Learn More on Yale MedicineAlcohol Use Disorder
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Board Certifications
Addiction Medicine (Internal Medicine)
- Certification Organization
- AB of Addiction Medicine
- Latest Certification Date
- 2024
- Original Certification Date
- 2014
HIV Specialist
- Certification Organization
- American Academy of HIV Medicine
- Latest Certification Date
- 2021
- Original Certification Date
- 2013
Yale Medicine News
News
News
- May 27, 2025
Research Project Studies High Doses of an Opioid Use Disorder Medication Among Veterans
- December 02, 2024
2025 YCCI Funding Opportunities Open for Applications
- October 23, 2024
Penicillin Allergies Among Patients Undergoing Hematopoietic Stem Cell Transplants
- August 05, 2024
Yale partnership seeks to improve HIV prevention and treatment training in Tbilisi, Georgia
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Contacts
Appointment Number
Clinic Fax Number
Mailing Address
General Internal Medicine
PO Box 208056
New Haven, CT 06520-8025
United States
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