Ernest Asare, PhD
Associate Research Scientist in Epidemiology (Microbial Diseases)Cards
About
Research
Publications
2025
Global estimates of rotavirus vaccine efficacy and effectiveness: a rapid review and meta-regression analysis
Prunas O, Asare E, Sajewski E, Li Y, Pithawala Z, Weinberger D, Warren J, Armah G, Cunliffe N, Iturriza-Gómara M, Lopman B, Pitzer V. Global estimates of rotavirus vaccine efficacy and effectiveness: a rapid review and meta-regression analysis. EClinicalMedicine 2025, 81: 103122. PMID: 40115174, PMCID: PMC11925534, DOI: 10.1016/j.eclinm.2025.103122.Peer-Reviewed Original ResearchRotavirus-associated gastroenteritisRotavirus vaccine efficacyPredicting vaccine efficacyVaccine efficacyVaccine effectivenessVaccine performanceNational rotavirus immunization programImpact of rotavirus vaccinationRotavirus immunization programAffecting young childrenBill &Meta-regression analysisRandomized controlled trialsSystematic review of studiesEstimates of vaccine effectivenessRotavirus morbidityMelinda Gates FoundationRotavirus vaccineCohort studyLicensed vaccinesVaccine trialsDecreased efficacyControlled trialsCase-controlLow-income settingsLong-term drought and risk of infant mortality in Africa: A cross-sectional study
Wang P, Rogne T, Warren J, Asare E, Akum R, Toure N, Ross J, Chen K. Long-term drought and risk of infant mortality in Africa: A cross-sectional study. PLOS Medicine 2025, 22: e1004516. PMID: 39888958, PMCID: PMC11785314, DOI: 10.1371/journal.pmed.1004516.Peer-Reviewed Original ResearchConceptsRisk of infant mortalityInfant mortality riskCross-sectional studyInfant mortalityMortality riskIncreased risk of infant mortalityIncreased risk of neonatal mortalityIncreased riskRisk of neonatal mortalityHealth Surveys ProgramPost-neonatal mortalityCox regression modelsStatistically significant associationChild healthGlobal burdenNon-casesNeonatal mortalitySignificant associationImpact mortalityNon-exposureSurvival periodRegression modelsPregnancyMortalityHealth
2024
Impact of dosing schedules on performance of rotavirus vaccines in Ghana
Asare E, Al-Mamun M, Armah G, Lopman B, Pitzer V. Impact of dosing schedules on performance of rotavirus vaccines in Ghana. Science Advances 2024, 10: eadn4176. PMID: 39661683, PMCID: PMC11633732, DOI: 10.1126/sciadv.adn4176.Peer-Reviewed Original ResearchConceptsVaccine dosing schedulesDosing scheduleDoses of RV1Median percentage reductionImprove vaccine performanceRotavirus vaccine impactThird doseRotavirus vaccineRotarix vaccineVaccine impactAdditional doseVaccine effectivenessVaccine performanceVaccineRotavirusRV1Percentage reductionChildrenRotarixImpact of rotavirus vaccination in Malawi from 2012 to 2022 compared to model predictions
Pitzer V, Ndeketa L, Asare E, Hungerford D, Lopman B, Jere K, Cunliffe N. Impact of rotavirus vaccination in Malawi from 2012 to 2022 compared to model predictions. Npj Vaccines 2024, 9: 227. PMID: 39562592, PMCID: PMC11576906, DOI: 10.1038/s41541-024-01008-6.Peer-Reviewed Original ResearchRotavirus-associated gastroenteritisRotavirus-negative childrenRotavirus-negative controlsImpact of rotavirus vaccinationVaccination coverageRotavirus vaccine impactAcute gastroenteritis casesNational immunization programPre-vaccination dataVaccine introductionRotavirus vaccineVaccine impactAcute gastroenteritisVaccine effectivenessGastroenteritis casesLow-income settingsImmunization programsVaccine
2023
Floods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries
Wang P, Asare E, Pitzer V, Dubrow R, Chen K. Floods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries. JAMA Pediatrics 2023, 177: 1206-1214. PMID: 37782513, PMCID: PMC10546297, DOI: 10.1001/jamapediatrics.2023.3964.Peer-Reviewed Original ResearchConceptsMiddle-income countriesDiarrhea riskOdds ratioMAIN OUTCOMEMixed-effects logistic regression modelRisk of diarrheaCross-sectional studyHigher odds ratioPrevalence of diarrheaLogistic regression modelsHealth survey programUnexposed childrenEffect modificationChild healthDiarrhea prevalenceSurvey clustersSignificant associationHygiene practicesFourth weekWeeksStrong associationRandom interceptYoung childrenChildrenDiarrheaClimate Drivers of Malaria Transmission Seasonality and Their Relative Importance in Sub‐Saharan Africa
Yamba E, Fink A, Badu K, Asare E, Tompkins A, Amekudzi L. Climate Drivers of Malaria Transmission Seasonality and Their Relative Importance in Sub‐Saharan Africa. GeoHealth 2023, 7: e2022gh000698. PMID: 36743738, PMCID: PMC9884660, DOI: 10.1029/2022gh000698.Peer-Reviewed Original Research
2022
Malaria metrics distribution under global warming: assessment of the VECTRI malaria model over Cameroon
Mbouna A, Tamoffo A, Asare E, Lenouo A, Tchawoua C. Malaria metrics distribution under global warming: assessment of the VECTRI malaria model over Cameroon. International Journal Of Biometeorology 2022, 67: 93-105. PMID: 36258135, DOI: 10.1007/s00484-022-02388-x.Peer-Reviewed Original ResearchAssociations between long-term drought and diarrhea among children under five in low- and middle-income countries
Wang P, Asare E, Pitzer VE, Dubrow R, Chen K. Associations between long-term drought and diarrhea among children under five in low- and middle-income countries. Nature Communications 2022, 13: 3661. PMID: 35773263, PMCID: PMC9247069, DOI: 10.1038/s41467-022-31291-7.Peer-Reviewed Original ResearchThe influence of demographic and meteorological factors on temporal patterns of rotavirus infection in Dhaka, Bangladesh
Asare EO, Al-Mamun MA, Sarmin M, Faruque ASG, Ahmed T, Pitzer VE. The influence of demographic and meteorological factors on temporal patterns of rotavirus infection in Dhaka, Bangladesh. Proceedings Of The Royal Society B 2022, 289: 20212727. PMID: 35673869, PMCID: PMC9174722, DOI: 10.1098/rspb.2021.2727.Peer-Reviewed Original ResearchCase fatality risk of diarrhoeal pathogens: a systematic review and meta-analysis
Asare EO, Hergott D, Seiler J, Morgan B, Archer H, Wiyeh AB, Guo B, Driver M, Giersing B, Hasso-Agopsowicz M, Lingappa J, Lopman BA, Pitzer VE. Case fatality risk of diarrhoeal pathogens: a systematic review and meta-analysis. International Journal Of Epidemiology 2022, 51: 1469-1480. PMID: 35578827, PMCID: PMC9557849, DOI: 10.1093/ije/dyac098.Peer-Reviewed Original ResearchConceptsCase fatality riskDiarrhoeal pathogensEnteropathogenic Escherichia coliSystematic reviewMultilevel mixed-effects logistic regression modelsMixed-effects logistic regression modelLower odds ratioOverall case fatality riskRandom-effects modelLogistic regression modelsDiarrhoea mortalityPrimary outcomeFatality riskOdds ratioMortality rateVaccine developmentAge groupsEnteric pathogensPotential predictorsBurden modelMore studiesReview criteriaConsiderable heterogeneityDifferent pathogensCFR estimates