Erica Spatz, MD, MHS
Associate Professor of Cardiology and Associate Professor of Epidemiology (Chronic Diseases)Cards
About
Research
Publications
2026
Primary Prevention Antihypertensive Eligibility With the 2025 AHA/ACC Guideline
Malik D, Essa M, Lu Y, Yang H, Spatz E, Krumholz H, Faridi K. Primary Prevention Antihypertensive Eligibility With the 2025 AHA/ACC Guideline. Hypertension 2026, 83: e26387. PMID: 41849572, DOI: 10.1161/hypertensionaha.125.26387.Peer-Reviewed Original ResearchAssociation Between Retinal Vascular Occlusions and Stroke in Individuals With Atrial Fibrillation.
Jayaraj C, Eisen J, Jin A, Faulkner S, Miguez S, Spatz E, Bakhoum C, Bakhoum M. Association Between Retinal Vascular Occlusions and Stroke in Individuals With Atrial Fibrillation. Journal Of The American Heart Association 2026, 15: e043029. PMID: 41717858, DOI: 10.1161/jaha.125.043029.Peer-Reviewed Original ResearchShared Decision-Making and Patient Decision Aids for Percutaneous Left Atrial Appendage Occlusion
Rager J, Huang C, Zimmerman S, Dhruva S, Freeman J, Matlock D, Minges K, Sandhu A, Spatz E, Varosy P, Caverly T. Shared Decision-Making and Patient Decision Aids for Percutaneous Left Atrial Appendage Occlusion. JAMA Network Open 2026, 9: e2556937. PMID: 41686441, PMCID: PMC12905655, DOI: 10.1001/jamanetworkopen.2025.56937.Peer-Reviewed Original ResearchConceptsShared decision-makingCenters for Medicare & Medicaid ServicesPatient decision aidsNational Cardiovascular Data RegistryDecision aidCohort studyCenters for Medicare & Medicaid Services requirementsUnadjusted ratesDA useNational Cardiovascular Data Registry LAAO RegistryPercutaneous left atrial appendage occlusionAmerican College of Cardiology National Cardiovascular Data RegistryAmerican CollegeUnique patient encountersHierarchical logistic regressionProportion of encountersCohort study of patientsStudy periodPatient encountersMedicaid ServicesMain OutcomesUnadjusted analysisData registryLogistic regressionInstitutional levelSpatial and racial/ethnic disparities in cardiovascular mortality attributable to PM2.5 components in the contiguous United States
Hu Y, Chu L, Renzetti S, Zang E, Opara I, Lu Y, Spatz E, Krumholz H, Chen K. Spatial and racial/ethnic disparities in cardiovascular mortality attributable to PM2.5 components in the contiguous United States. Science Advances 2026, 12: eadx2075. PMID: 41604483, PMCID: PMC12851041, DOI: 10.1126/sciadv.adx2075.Peer-Reviewed Original ResearchConceptsLong-term exposure to fine particulate matterExposure to fine particulate matterContiguous United StatesFine particulate matterPM2.5 componentsParticulate matterBlack carbonCVD deathRacial/ethnic disparitiesNon-Hispanic blacksNon-Hispanic whitesCardiovascular diseaseRacial/ethnic groupsGeographic regionsTargeted interventionsUnited StatesEast North CentralRisk factorsDisparitiesRegression modelsNorth CentralMatterAtlanticCaliforniaCarbonLow levels of atherogenic lipoproteins and incident atherosclerotic cardiovascular disease: A pooled cohort primary prevention study
Faridi K, Quispe R, Martin S, Jones S, Blumenthal R, Saeed A, Lima J, Spatz E, Rana J, Michos E. Low levels of atherogenic lipoproteins and incident atherosclerotic cardiovascular disease: A pooled cohort primary prevention study. American Heart Journal 2026, 295: 107354. PMID: 41610901, DOI: 10.1016/j.ahj.2026.107354.Peer-Reviewed Original ResearchConceptsAtherosclerotic cardiovascular diseaseNon-HDL-CBaseline LDL-CLDL-C <Lipid-Lowering TherapyLDL-CMultivariable adjustmentASCVD riskBaseline LDL-C <High riskPrimary preventionAtherogenic lipoproteinsPrimary prevention of atherosclerotic cardiovascular diseasePrevention of atherosclerotic cardiovascular diseaseCardiovascular diseaseMultivariate Cox proportional hazardsLevels of atherogenic lipoproteinsMedian Follow-UpRisk of atherosclerotic cardiovascular diseaseAtherosclerotic cardiovascular disease riskPopulation-based prospective cohortAssociated with higher riskAtherosclerotic cardiovascular disease eventsLow-normal valuesLow-normal levelsObesity and Long COVID: intersecting epidemics?
Gottlieb M, Yu H, Chen J, Spatz E, Gentile N, Geyer R, Santangelo M, Malicki C, Gatling K, O’Laughlin K, Stephens K, Elmore J, Wisk L, L’Hommedieu M, Rodriguez R, Montoy J, Wang R, Rising K, Kean E, Dyal J, Hill M, Venkatesh A, Weinstein R. Obesity and Long COVID: intersecting epidemics? BMC Public Health 2026, 26: 626. PMID: 41566432, PMCID: PMC12911336, DOI: 10.1186/s12889-025-26134-1.Peer-Reviewed Original ResearchPersistent obesityHealth outcomesMental healthModerate-to-severe fatigueMental health outcomesPhysical health outcomesAssociation of obesitySignificant public health implicationsEffects of long COVIDStudy of participantsLong-term effectsLong COVIDPublic health implicationsObesity interventionsLC statusRate of LCObesity managementHigher RatesInfluence of obesityObesityHealth implicationsParticipantsHealthFollow-upSARS-CoV-2 infectionCardiovascular Statistics in the United States, 2026 JACC Stats
Wadhera R, Dhruva S, Bikdeli B, Bonaca M, Kittleson M, Ko D, Lu Y, Pagidipati N, Sawano M, Spatz E, Vaduganathan M, Wasfy J, Yong C, Yang H, Zheng Z, Krumholz H, Curtis L. Cardiovascular Statistics in the United States, 2026 JACC Stats. Journal Of The American College Of Cardiology 2026, 87: 1094-1134. PMID: 41524687, DOI: 10.1016/j.jacc.2025.12.027.Peer-Reviewed Original ResearchConceptsQuality of careCardiovascular healthPeripheral arterial diseaseAcute myocardial infarctionPersistent health disparitiesPublic health professionalsRisk factors-hypertensionPopulation-based surveyRisk factorsCoronary heart diseaseHeart diseaseCardiovascular risk factorsUnited StatesHealth disparitiesHealth professionalsMyocardial infarctionHealth policySocioeconomic statusU.S. adultsVital statisticsAdministrative datasetsClinical registryJACCArtery diseaseHealth
2025
Long COVID as Intermediate Physiology Rethinking Autonomic Dysfunction and Medical Uncertainty
Sawano M, Spatz E, Sanders L. Long COVID as Intermediate Physiology Rethinking Autonomic Dysfunction and Medical Uncertainty. Journal Of The American College Of Cardiology 2025, 87: 231-233. PMID: 41405529, DOI: 10.1016/j.jacc.2025.10.083.Peer-Reviewed Original ResearchConfronting the Global Rise of Obesity and Cardiovascular Disease The Role of GLP-1 RAs
Spatz E. Confronting the Global Rise of Obesity and Cardiovascular Disease The Role of GLP-1 RAs. Journal Of The American College Of Cardiology 2025, 86: 2155-2157. PMID: 41298033, DOI: 10.1016/j.jacc.2025.09.1599.Peer-Reviewed Original ResearchGearing Up for Lipoprotein(a) Screening and Management Distributions and Risk in the Hispanic/Latino Population
Spatz E. Gearing Up for Lipoprotein(a) Screening and Management Distributions and Risk in the Hispanic/Latino Population. Journal Of The American College Of Cardiology 2025, 86: 2311-2313. PMID: 41338841, DOI: 10.1016/j.jacc.2025.10.034.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Clinical Care
Overview
Erica Spatz, MD, MHS, is a general cardiologist who treats a variety of conditions that relate to the heart and circulatory system. In addition to emphasizing prevention to her patients, she is an active researcher who investigates ways to prevent heart attacks and strokes, so that more people can live long and healthy lives.
“The field of prevention is exciting. We are rapidly developing new ways of estimating people’s risk of future heart disease, and we have new medications and tools to reduce that risk,” says Dr. Spatz, who is especially interested in applying “precision medicine” to prevention. This is making conversations with patients in her practice more specific and less generic. “I am thinking, ‘What are the patient’s risk factors? What's unique about their biology, their genetics, and their biography? What are the aspects of their lives that may be contributing to cardiovascular risk or, on the contrary, promoting cardiovascular health? What might be the best strategies for reducing risk and improving their health outcomes?’ The onus is on us as clinicians, physicians, nurses, and pharmacists, to really understand the person before us.”
We need to be working at multiple levels to reduce heart disease, Spatz says. “We need strong policies and coordinated community efforts to promote healthier lifestyles and overall well-being. There is so much we can be doing to make ‘healthy’ the easy choice for our population. At the individual level, there is an opportunity to better capture the personalized biological factors, experiences, and behaviors that inform cardiovascular risk—through digital technology and surveys.”
Lifestyle changes are often considered the bedrock of preventing heart disease, and while this can be difficult for some people—especially if they are overwhelmed with other life challenges—small achievable goals go a long way, Dr. Spatz says. “I try to think about this from a lifelong perspective. Cardiovascular disease prevention is hard work and people can't be perfect all the time, so I try to find specific things people can work on as well as opportunities when this makes sense in a person's life. If I can help them to define a healthier path, then I think the ripple effects can be massive.”
In addition to caring for patients, Dr. Spatz serves as a clinical investigator for the Center for Outcomes Research & Evaluation (CORE), an organization at Yale School of Medicine that focuses on health care quality, where she researches individualized approaches to preventing and managing cardiovascular disease, health disparities across the health care system, and ways to engage patients as partners in their care. She also is a cofounder of Project Access-New Haven—a network of physicians, hospitals, and community organizations partnering to provide donated specialty care to underserved patients in New Haven.
Clinical Specialties
Fact Sheets
Heart Attack (Myocardial Infarction)
Learn More on Yale MedicineFamilial hypercholesterolemia
Learn More on Yale MedicineHypercholesterolemia (High Cholesterol)
Learn More on Yale MedicineCOVID-19
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Yale Medicine News
News & Links
News
- March 16, 2026Source: Yale Medicine
Should You Take a Statin for Your High Cholesterol?
- January 31, 2026Source: The Charlotte Observer Online (with Dr. Erica Spatz)
7 Things All Women Should Know About Their Heart Health
- December 29, 2025Source: Yahoo UK - Yahoo Movies UK
75% of US adults may meet criteria for obesity under new definition, study finds
- December 01, 2025
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Cardiovascular Medicine
789 Howard Avenue, PO Box 208017
New Haven, CT 06520-8017
United States
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Events
Everyone Lavanya Bellumkonda, MD - Andrew Y. Chang, MD, PhD - Kai Chen, PhD - Yuan Lu, ScD - Jodi Sherman, MD - Erica Spatz, MD, MHSZoom link will be shared after registration.