Elisabete Weiderpass
Professor AdjunctCards
About
Research
Publications
2025
The 3V score and joint associations of low ultra-processed food, biodiverse and plant-based diets on colorectal cancer risk: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study
Cakmak E, Al Nahas A, Chimera B, Hanley-Cook G, Berden J, Fardet A, Rock E, Biessy C, Nicolas G, Kliemann N, Rauber F, Levy R, Mangone L, Touvier M, Srour B, Kesse-Guyot E, Lachat C, Skeie G, Weiderpass E, Jannasch F, Dahm C, Ibsen D, Dahl C, Kyrø C, Hajji-Louati M, Marques C, Severi G, Katzke V, Kaaks R, Schulze M, Caini S, Sieri S, De Magistris M, Tumino R, Sacerdote C, Zamora-Ros R, Sánchez M, Jimenez-Zabala A, Gómez J, Guevara M, Riboli E, Gunter M, Huybrechts I, Vineis P, Robinson O. The 3V score and joint associations of low ultra-processed food, biodiverse and plant-based diets on colorectal cancer risk: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. EClinicalMedicine 2025, 90: 103662. PMID: 41438976, PMCID: PMC12719066, DOI: 10.1016/j.eclinm.2025.103662.Peer-Reviewed Original ResearchUltra-processed foodsColorectal cancer riskRisk of colorectal cancerEuropean Prospective InvestigationAssociated with lower riskCancer riskJoint associationsAssociated with colon cancer riskLower risk of colorectal cancerUltra-processed food intakeProspective InvestigationMultivariable-adjusted Cox regression modelsColorectal cancer ratesDistal colon cancerProspective European Prospective InvestigationCancer and NutritionColorectal cancerColon cancer riskMiddle-aged participantsCancer ratesLowest quintileDiet indexEPIC cohortInverse associationDietary patternsIntake of total, classes, and subclasses of (poly)phenols and risk of lymphoid neoplasms: a prospective analysis in the EPIC cohort
Almanza-Aguilera E, Guananga-Álvarez D, Benavente Y, Nieters A, Besson C, Saberi Hosnijeh F, Kyrø C, Bondonno N, Dahm C, Weiderpass E, Truong T, Louati-hajji M, Ren X, Katzke V, Schulze M, Pasanisi F, Vener C, Masala G, Giraudo M, Tumino R, Aizpurua A, Sánchez M, Huerta J, Guevara M, Lasheras C, Vineis P, Vermeulen R, Zamora-Ros R, Casabonne D. Intake of total, classes, and subclasses of (poly)phenols and risk of lymphoid neoplasms: a prospective analysis in the EPIC cohort. British Journal Of Cancer 2025, 133: 1864-1871. PMID: 41044175, PMCID: PMC12689600, DOI: 10.1038/s41416-025-03228-6.Peer-Reviewed Original ResearchConceptsAssociated with riskHodgkin lymphomaIsoflavone intakeEPIC cohortRisk of lymphoid neoplasmsMature B-cell lymphomasAssociated with Hodgkin lymphomaMultivariable-adjusted Cox proportional hazards modelsNon-Hodgkin's lymphomaB-cell lymphomaRisk of lymphomaRisk of HLIncident lymphoma casesCox proportional hazards modelsNo significant associationProportional hazards modelTotal intakeLymphoma subtypesFlavone intakeLymphoma casesLymphoid neoplasmsLymphoma developmentLymphoma riskCell neoplasmsFrequent subtypeIn the framework of the EU Trio Presidency–supporting the European Code Against Cancer
Koczkodaj P, Damianos M, Jagielska B, Weiderpass E, Schüz J. In the framework of the EU Trio Presidency–supporting the European Code Against Cancer. The Lancet Regional Health - Europe 2025, 57: 101451. PMID: 40917995, PMCID: PMC12410580, DOI: 10.1016/j.lanepe.2025.101451.Peer-Reviewed Original ResearchBiodiverse diets present co-benefits for greenhouse gas emissions, land use, mortality rates and nutritional adequacy in Europe
Berden J, Chimera B, Hanley-Cook G, Cakmak E, Vineis P, Nicolas G, Skeie G, Srour B, Kesse-Guyot E, Touvier M, Baudry J, Deschasaux-Tanguy M, Berlivet J, van der Schouw Y, Murray K, Jannasch F, Tjønneland A, Kyrø C, Dahm C, Ibsen D, Le Cornet C, Schulze M, Mangone L, Marques C, Weiderpass E, Heath A, Severi G, Cadeau C, Jiménez-Zabala A, Sodano B, Castro-Espin C, Castilla J, Tsilidis K, Chirlaque M, Sánchez M, Contiero P, Panico S, Katzke V, Gunter M, Ferrari P, Lachat C, Huybrechts I. Biodiverse diets present co-benefits for greenhouse gas emissions, land use, mortality rates and nutritional adequacy in Europe. Nature Food 2025, 6: 857-867. PMID: 40835792, DOI: 10.1038/s43016-025-01214-y.Peer-Reviewed Original ResearchConceptsDietary species richnessPotential adverse environmental impactsGreenhouse gas emissionsLand useDiet scoreAssociated with probabilityCo-benefitsGas emissionsNutrient adequacyEnvironmental impacts of dietsMortality ratePublic health nutritionEnvironmental healthAssociated with greenhouse gas emissionsHealth nutritionSpecies richnessAssociated with mortality ratesPlant biodiversityAnimal-source foodsStudy participantsDietary diversityImpact of dietNutritional adequacyPositive associationGreenhouseSex Disparities and Female Reproductive and Hormonal Factors Associated with Risk of Pancreatic Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort
Katzke V, Dutta S, Rasokat A, Archibugi L, Capurso G, Peduzzi G, Gentiluomo M, Canzian F, Eriksen A, Tjønneland A, Dahm C, Truong T, Canonico M, Laouali N, Schulze M, Tumino R, Masala G, Agnoli C, Dansero L, Panico S, Crous-Bou M, Molina-Montes E, Dorronsoro A, Chirlaque M, Guevara M, Butt S, Sund M, Christakoudi S, Aglago E, Weiderpass E, Gunter M, Campa D, Kaaks R. Sex Disparities and Female Reproductive and Hormonal Factors Associated with Risk of Pancreatic Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort. Cancers 2025, 17: 2275. PMID: 40723159, PMCID: PMC12293992, DOI: 10.3390/cancers17142275.Peer-Reviewed Original ResearchEuropean Prospective InvestigationRisk of PCAssociated with riskHigher incidence of pancreatic cancerPC riskProspective InvestigationRisk of pancreatic cancerAssociated with PC riskDuration of HRT useIncidence of pancreatic cancerCancer and NutritionPancreatic cancerRisk factorsChild-bearing womenDuration of breastfeedingFull-term pregnancySex-related risk factorsCox proportional hazards modelsMonths of breastfeedingAssociation of PCCumulative durationProportional hazards modelAssociated with risk of PCMethods:HRT useLung cancer screening in Europe: a golden opportunity to address tobacco use through scalable, WHO-guided cessation interventions
Sheikh M, Weiderpass E. Lung cancer screening in Europe: a golden opportunity to address tobacco use through scalable, WHO-guided cessation interventions. European Respiratory Journal 2025, 65: 2500124. PMID: 40537166, DOI: 10.1183/13993003.00124-2025.Peer-Reviewed Original ResearchAssociation Between Dietary Intake and Blood Concentrations of One-Carbon-Metabolism-Related Nutrients in European Prospective Investigation into Cancer and Nutrition
Park J, Van Puyvelde H, Regazzetti L, Clasen J, Heath A, Eussen S, Ueland P, Johansson M, Biessy C, Zamora-Ros R, Huerta J, Sánchez M, Ocke M, Schulze M, Schiborn C, Braaten T, Skeie G, Sacerdote C, Castilla J, Karlsson T, Johansson I, Kyrø C, Tjønneland A, Tong T, Katzke V, Bajracharya R, Lasheras C, Midttun Ø, Vollset S, Vineis P, Masala G, Amiano P, Tumino R, Baldassari I, Weiderpass E, Riboli E, Gunter M, Freisling H, Rinaldi S, Muller D, Huybrechts I, Ferrari P. Association Between Dietary Intake and Blood Concentrations of One-Carbon-Metabolism-Related Nutrients in European Prospective Investigation into Cancer and Nutrition. Nutrients 2025, 17: 1970. PMID: 40573081, PMCID: PMC12195952, DOI: 10.3390/nu17121970.Peer-Reviewed Original ResearchConceptsEuropean Prospective InvestigationDietary intakeBlood concentrationsProspective InvestigationOne-carbon metabolism-related nutrientsDietary intake of betaineNested Case-Control StudyCancer and NutritionVitamin B6Individual dietary intakeAssociated with folateVitamin B12Vitamin supplement useWeak to moderate associationsCase-control studyCase-control statusIntake of betaineConcentrations of homocysteineSupplement useSmoking statusAssociated with methionineModerate associationBloodFolateIntakeAssociation between endometriosis and type and age of menopause: a pooled analysis of 279 948 women from five cohort studies
Chung H, Hayashi K, Dobson A, Sandin S, Ideno Y, Hardy R, Weiderpass E, Mishra G. Association between endometriosis and type and age of menopause: a pooled analysis of 279 948 women from five cohort studies. Human Reproduction 2025, 40: 1210-1219. PMID: 40304605, PMCID: PMC12127511, DOI: 10.1093/humrep/deaf068.Peer-Reviewed Original ResearchConceptsPremature ovarian insufficiencySpontaneous premature ovarian insufficiencySurgical menopauseNatural menopauseAge of menopauseBilateral oophorectomyOvarian reserveEarly menopauseMenopausal ageCohort studyHazard ratioIncreased riskMenopause typeOdds ratioInternational Agency for Research on CancerImpact ovarian reservePremature surgical menopauseMenopausal hormone therapyStages of endometriosisPremenopausal bilateral oophorectomyManagement of endometriosisMonitoring of womenOvarian preservationPremenopausal hysterectomyFine-Gray subdistribution hazard modelPhysical activity and mortality in melanoma patients within the Norwegian Women and Cancer study (NOWAC)
Perrier F, Ahimbisibwe A, Ghiasvand R, Rueegg C, Green A, Borch K, Braaten T, Weiderpass E, Valberg M, Robsahm T, Veierød M. Physical activity and mortality in melanoma patients within the Norwegian Women and Cancer study (NOWAC). International Journal Of Cancer 2025, 157: 846-857. PMID: 40181554, DOI: 10.1002/ijc.35430.Peer-Reviewed Original ResearchPre-diagnosis PAPre-DiagnosisPA levelsPhysical activityNorwegian womenPost-diagnosis physical activityCancer Registry of NorwayPopulation-based Norwegian WomenPost-diagnosis PAMelanoma-specific mortalityMiddle-aged Norwegian womenAssociated with lower riskOverall mortalityRegion of residenceTrajectory classesAssociated with decreased mortalityLatent class mixed modelsCancer RegistryOther causesSmoking statusDecreased riskSummary stageMelanoma diagnosisCancer studiesCancer cohortIdentifying Metabolomic Mediators of the Physical Activity and Colorectal Cancer Relationship
Papadimitriou N, Kazmi N, Tsilidis K, Richmond R, Lynch B, Bendinelli B, Ricceri F, Sánchez M, Trobajo-Sanmartín C, Jakszyn P, Simeon V, Severi G, Perduca V, Truong T, Ferrari P, Keski-Rahkonen P, Weiderpass E, Eichelmann F, Schulze M, Katzke V, Fortner R, Heath A, Aune D, Harewood R, Dahm C, Llorente A, Gunter M, Murphy N, Lewis S. Identifying Metabolomic Mediators of the Physical Activity and Colorectal Cancer Relationship. Cancer Epidemiology Biomarkers & Prevention 2025, 34: 578-587. PMID: 39883068, PMCID: PMC11966109, DOI: 10.1158/1055-9965.epi-24-1390.Peer-Reviewed Original ResearchPhysical activityPA levelsReduced risk of colorectal cancerAssociated with CRC riskColorectal cancerRisk of colorectal cancerFalse discovery rate correctionColorectal cancer riskCancer prevention interventionsNested Case-Control StudyMetabolomic signaturesCase-control studyCancer relationshipCRC riskBaseline questionnairePA measuresEPIC cohortPreventive interventionsInverse associationPA indexPhosphatidylcholine acyl-alkylReduced riskMediation analysisMetabolomics panelCirculating metabolome