Featured Publications
C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study
Meyer AJ, Ochom E, Turimumahoro P, Byanyima P, Sanyu I, Lalitha R, Kaswabuli S, Andama A, Walter ND, Katamba A, Cattamanchi A, Worodria W, Huang L, Yoon C, Davis JL. C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study. Journal Of Clinical Microbiology 2020, 59: 10.1128/jcm.02162-20. PMID: 33087439, PMCID: PMC7771459, DOI: 10.1128/jcm.02162-20.Peer-Reviewed Original ResearchConceptsC-reactive proteinEnzyme-linked immunosorbent assayTriage testUtility of CRPC-reactive protein testingCulture-positive pulmonary tuberculosisProspective cross-sectional studySerum C-reactive proteinDiagnostic performanceHIV-seronegative individualsTB triage testNational Referral HospitalCross-sectional studyNegative predictive valueNegative likelihood ratioDiagnostic accuracy studiesActive tuberculosisPulmonary tuberculosisTB screeningReferral hospitalIllness severityCRP testingSputum samplesManufacturer's thresholdPredictive valueImplementing mHealth Interventions in a Resource-Constrained Setting: Case Study From Uganda
Meyer AJ, Armstrong-Hough M, Babirye D, Mark D, Turimumahoro P, Ayakaka I, Haberer JE, Katamba A, Davis JL. Implementing mHealth Interventions in a Resource-Constrained Setting: Case Study From Uganda. JMIR MHealth And UHealth 2020, 8: e19552. PMID: 32673262, PMCID: PMC7385635, DOI: 10.2196/19552.Peer-Reviewed Original ResearchConceptsEnd usersCommunity health workersComplex data structuresData management plansLack of adaptabilityDigital fingerprintingMHealth interventionsData managementData structureDigital servicesContact investigationHardware requirementsSMS messagesUse of technologyHealth interventionsComplex mHealth interventionExcessive complexityTB contact investigationTuberculosis contact investigationMobile health interventionsTechnology requirementsSurvey appPublic health interventionsResource-constrained settingsUsersSputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda
Meyer AJ, Atuheire C, Worodria W, Kizito S, Katamba A, Sanyu I, Andama A, Ayakaka I, Cattamanchi A, Bwanga F, Huang L, Davis JL. Sputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda. PLOS ONE 2017, 12: e0180572. PMID: 28686705, PMCID: PMC5501569, DOI: 10.1371/journal.pone.0180572.Peer-Reviewed Original ResearchConceptsGeneXpert MTB/RIFBlood-stained sputumSputum qualityMTB/RIFSalivary sputumXpert testingDiagnostic performanceMycobacterial cultureCross-sectional studyTB patientsPatient factorsSputum testTB diagnosisDiagnostic yieldMucoid sputumSputum samplesLED fluorescence microscopySputumXpertTuberculosis diagnosticsDemographic informationPatientsAdditional testingHigher proportionSample types
2022
Assessing a norming intervention to promote acceptance of HIV testing and reduce stigma during household tuberculosis contact investigation: protocol for a cluster-randomised trial
Armstrong-Hough M, Ggita J, Gupta AJ, Shelby T, Nangendo J, Ayen DO, Davis JL, Katamba A. Assessing a norming intervention to promote acceptance of HIV testing and reduce stigma during household tuberculosis contact investigation: protocol for a cluster-randomised trial. BMJ Open 2022, 12: e061508. PMID: 35613785, PMCID: PMC9134160, DOI: 10.1136/bmjopen-2022-061508.Peer-Reviewed Original ResearchConceptsCommunity health workersHIV testingHIV test uptakeHIV status awarenessHome HIV testingHousehold contactsContact investigationTB stigmaTest uptakeHIV stigmaPublic Health Institutional Review BoardHealth Institutional Review BoardTB contact investigationTuberculosis contact investigationCluster-randomised trialHousehold tuberculosis contact investigationPublic health facilitiesVerbal informed consentHuman Investigation CommitteeMakerere University SchoolInstitutional review boardUganda National CouncilProportion of contactsHome HIVStatus awarenessA cost analysis of implementing mobile health facilitated tuberculosis contact investigation in a low-income setting
Turimumahoro P, Tucker A, Gupta AJ, Tampi RP, Babirye D, Ochom E, Ggita JM, Ayakaka I, Sohn H, Katamba A, Dowdy D, Davis JL. A cost analysis of implementing mobile health facilitated tuberculosis contact investigation in a low-income setting. PLOS ONE 2022, 17: e0265033. PMID: 35363783, PMCID: PMC8975098, DOI: 10.1371/journal.pone.0265033.Peer-Reviewed Original ResearchConceptsCommunity health workersTuberculosis contact investigationHousehold contactsContact investigationHome-based HIV testingContact investigation strategyHIV testing servicesPatient-provider communicationHome-based strategiesResource-limited settingsLow-income settingsUgandan health systemTB evaluationActive TBHIV testingSputum collectionSputum samplesHealth workersProgram implementationHealth servicesMHealth strategiesHealth systemProgram reachMobile health applicationsRoutine implementationTheory-Informed Design of a Tailored Strategy for Implementing Household TB Contact Investigation in Uganda
Davis JL, Ayakaka I, Ggita JM, Ochom E, Babirye D, Turimumahoro P, Gupta AJ, Mugabe FR, Armstrong-Hough M, Cattamanchi A, Katamba A. Theory-Informed Design of a Tailored Strategy for Implementing Household TB Contact Investigation in Uganda. Frontiers In Public Health 2022, 10: 837211. PMID: 35400072, PMCID: PMC8987305, DOI: 10.3389/fpubh.2022.837211.Peer-Reviewed Original ResearchConceptsContact investigationBehaviour Change Wheel frameworkMulti-component implementation strategyHousehold contact investigationTB contact investigationCommon infectious causeMultiple behavior change techniquesCluster-randomized trialEvidence-based interventionsWheel frameworkWorld Health OrganizationBehaviour change techniquesUsual careActive tuberculosisInfectious causesMiddle-income countriesHistorical controlsImplementation strategiesParallel mixed-methods studyMicro-randomized trialCOM-B modelBCW frameworkHealth OrganizationTuberculosisMixed-methods study
2020
Experiences and intentions of Ugandan household tuberculosis contacts receiving test results via text message: an exploratory study
Ggita JM, Katahoire A, Meyer AJ, Nansubuga E, Nalugwa T, Turimumahoro P, Ochom E, Ayakaka I, Haberer JE, Katamba A, Armstrong-Hough M, Davis JL. Experiences and intentions of Ugandan household tuberculosis contacts receiving test results via text message: an exploratory study. BMC Public Health 2020, 20: 310. PMID: 32164612, PMCID: PMC7068887, DOI: 10.1186/s12889-020-8427-0.Peer-Reviewed Original ResearchConceptsLay health workersHousehold contactsWorld Health OrganizationContact investigationBackgroundThe World Health OrganizationHousehold contact investigationTB-positive resultHigh-burden countriesHousehold tuberculosis contactTuberculosis contactsSputum collectionTB statusHealth workersShort message serviceFurther evaluationTuberculosisThematic saturationHealth OrganizationTB resultsNegative resultsStatus awarenessReliefSemi-structured interviewsText messagesDelivery
2018
Feasibility, Acceptability, and Adoption of Digital Fingerprinting During Contact Investigation for Tuberculosis in Kampala, Uganda: A Parallel-Convergent Mixed-Methods Analysis
White EB, Meyer AJ, Ggita JM, Babirye D, Mark D, Ayakaka I, Haberer JE, Katamba A, Armstrong-Hough M, Davis JL. Feasibility, Acceptability, and Adoption of Digital Fingerprinting During Contact Investigation for Tuberculosis in Kampala, Uganda: A Parallel-Convergent Mixed-Methods Analysis. Journal Of Medical Internet Research 2018, 20: e11541. PMID: 30442637, PMCID: PMC6265600, DOI: 10.2196/11541.Peer-Reviewed Original ResearchConceptsTechnology Acceptance Model 2Digital fingerprintingDigital fingerprintUnique patient identificationData integrityFingerprint captureSoftware leadFingerprint scannerPatient identificationHardware failureDigital technologiesBiometricsModest clusteringClusteringSocial imageTechnologyHousehold tuberculosis contact investigationRobust covariance estimatorPotential solutionsActual useGuide improvementFrameworkHardwareIndividual identificationTemporal characteristics‘Something so hard': a mixed-methods study of home sputum collection for tuberculosis contact investigation in Uganda
Armstrong-Hough M, Ggita J, Turimumahoro P, Meyer AJ, Ochom E, Dowdy D, Cattamanchi A, Katamba A, Davis JL. ‘Something so hard': a mixed-methods study of home sputum collection for tuberculosis contact investigation in Uganda. The International Journal Of Tuberculosis And Lung Disease 2018, 22: 1152-1159. PMID: 30236182, PMCID: PMC6496950, DOI: 10.5588/ijtld.18.0129.Peer-Reviewed Original ResearchConceptsLay health workersSputum collectionContact investigationHome-based collectionTB contact investigationContacts of patientsTuberculosis contact investigationDiagnosis of tuberculosisActive tuberculosisPrompt evaluationRisk factorsEnhanced interventionsIndex patientsConvergent mixed-methods studyHealth workersHome visitsSputumClinical settingTuberculosisMixed-methods studyMixed-method studyPatientsContact interviewsFocus group discussionsInterventionPatterns of usage and preferences of users for tuberculosis-related text messages and voice calls in Uganda
Ggita JM, Ojok C, Meyer AJ, Farr K, Shete PB, Ochom E, Turimumahoro P, Babirye D, Mark D, Dowdy D, Ackerman S, Armstrong-Hough M, Nalugwa T, Ayakaka I, Moore D, Haberer JE, Cattamanchi A, Katamba A, Davis JL. Patterns of usage and preferences of users for tuberculosis-related text messages and voice calls in Uganda. The International Journal Of Tuberculosis And Lung Disease 2018, 22: 530-536. PMID: 29663958, PMCID: PMC6350252, DOI: 10.5588/ijtld.17.0521.Peer-Reviewed Original ResearchConceptsClinic attendeesHousehold contactsTB patientsClinic visitsClinic patientsMHealth interventionsTuberculosisMobile phone accessHealth communicationPatientsUrban KampalaMost contactPhone accessPhone sharingLittle informationAttendeesText messagesPatterns of usageShort messaging service (SMS) messagesUgandaCentral UgandaVisitsRecipients
2017
Drop-out from the tuberculosis contact investigation cascade in a routine public health setting in urban Uganda: A prospective, multi-center study
Armstrong-Hough M, Turimumahoro P, Meyer AJ, Ochom E, Babirye D, Ayakaka I, Mark D, Ggita J, Cattamanchi A, Dowdy D, Mugabe F, Fair E, Haberer JE, Katamba A, Davis JL. Drop-out from the tuberculosis contact investigation cascade in a routine public health setting in urban Uganda: A prospective, multi-center study. PLOS ONE 2017, 12: e0187145. PMID: 29108007, PMCID: PMC5673209, DOI: 10.1371/journal.pone.0187145.Peer-Reviewed Original ResearchConceptsHousehold contact investigationNational TB ProgrammeContact investigationTB evaluationActive TBHealth workersPatient householdsMulti-center observational studyIndex TB patientsTB contact investigationLay health workersTuberculosis contact investigationMulti-center studyRoutine public health settingPublic health settingsTB patientsTB programsEligible contactsTuberculosis unitProgrammatic settingsRisk factorsIndex householdsIndex patientsObservational studyRisk contacts