Yuan Huang, PhD
Assistant Professor of Biostatistics (Biostatistics)Cards
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Assistant Professor of Biostatistics (Biostatistics)
Biography
Yuan Huang is an Assistant Professor in the Department of Biostatistics at Yale School of Public Health. Her methodological research is focused on statistical methods for high-dimensional data and has been motivated by challenges posted by analyzing cancer genomics, such as low reproducibly, nonlinearity, and heterogeneity. Applications from her work include biomarker identification, large-scale network structure estimation, GxE analysis, etc. She is particularly interested in integrative analysis that simultaneously analyzes multiple datasets to improve the discovery. Recently she collaborates extensively in neurodegenerative diseases and movement disorders, such as Alzheimer's disease, Huntington’s disease, and Parkinson's disease . She is also actively involved in collaborative research on clinical trials, genetics, epidemiology, and other biomedical fields.
Appointments
Biostatistics
Assistant ProfessorPrimary
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Education & Training
- PhD
- The Pennsylvania State University, Statistics
Research
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Public Health Interests
ORCID
0000-0002-8011-3034
Publications
2026
Unobserved heterogeneity in threshold regression based on the hitting times of a reflected Brownian motion for recurrent hypoglycemia
Xie Y, Fu H, Huang Y, Yan J. Unobserved heterogeneity in threshold regression based on the hitting times of a reflected Brownian motion for recurrent hypoglycemia. Lifetime Data Analysis 2026, 32: 36. PMID: 42228213, DOI: 10.1007/s10985-026-09717-x.Peer-Reviewed Original ResearchEmpowering classification for multivariate functional data with simultaneous feature selection.
Wang S, Cao G, Huang Y. Empowering classification for multivariate functional data with simultaneous feature selection. Statistical Methods In Medical Research 2026, 9622802261449366. PMID: 42138358, DOI: 10.1177/09622802261449366.Peer-Reviewed Original ResearchSubgroup Identification by Supervised Clustering Analysis of Disease Outcomes and Biomarkers with Repeated Measurements
Mao Y, Mou Y, Zhan X, Huang Y. Subgroup Identification by Supervised Clustering Analysis of Disease Outcomes and Biomarkers with Repeated Measurements. Journal Of Systems Science And Complexity 2026, 39: 1269-1284. DOI: 10.1007/s11424-026-5169-9.Peer-Reviewed Original ResearchCitationsGeneralizing the Finkelstein–Schoenfeld Test to Incorporate Multiple Alternating Thresholds
Mou Y, Kyriakides T, Hummel S, Li F, Huang Y. Generalizing the Finkelstein–Schoenfeld Test to Incorporate Multiple Alternating Thresholds. Biometrical Journal 2026, 68: e70117-e70117. PMID: 41761447, PMCID: PMC13052009, DOI: 10.1002/bimj.70117.Peer-Reviewed Original ResearchAltmetricAdaptive Incorporation of External Summary Information in the Cox Regression Under Population Heterogeneity
Li Y, Huang Y, Sheng Y, Zhang Q. Adaptive Incorporation of External Summary Information in the Cox Regression Under Population Heterogeneity. Statistics In Medicine 2026, 45: e70371. PMID: 41572651, DOI: 10.1002/sim.70371.Peer-Reviewed Original ResearchBHMnet: Bayesian high-dimensional mediation analysis with network information integration for correlated mediators
Im Y, Huang Y. BHMnet: Bayesian high-dimensional mediation analysis with network information integration for correlated mediators. Briefings In Bioinformatics 2026, 27: bbaf734. PMID: 41554050, PMCID: PMC12814977, DOI: 10.1093/bib/bbaf734.Peer-Reviewed Original ResearchCitationsDurability of Respiratory Syncytial Virus Vaccine Effectiveness Among US Veterans
Bajema K, Bui D, Yan L, Li Y, Rajeevan N, Vergun R, Sriskantharajah V, Hynes D, Berry K, Huang Y, Lin H, Aslan M, Ioannou G. Durability of Respiratory Syncytial Virus Vaccine Effectiveness Among US Veterans. JAMA Internal Medicine 2026, 186: 78-88. PMID: 41284307, PMCID: PMC12645397, DOI: 10.1001/jamainternmed.2025.6355.Peer-Reviewed Original ResearchCitationsAltmetric
2025
Effectiveness of the 2024–2025 KP.2 COVID-19 vaccines in the United States during long-term follow-up
Ioannou G, Berry K, Yan L, Huang Y, Lin H, Bui D, Hynes D, Boyko E, Ferguson J, Aslan M, Bajema K. Effectiveness of the 2024–2025 KP.2 COVID-19 vaccines in the United States during long-term follow-up. Nature Communications 2025, 17: 1043. PMID: 41444246, PMCID: PMC12847879, DOI: 10.1038/s41467-025-67796-0.Peer-Reviewed Original ResearchCitationsAltmetricImpact of time zero designation on estimated COVID-19 antiviral effectiveness in observational studies
Bajema K, Yan L, Berry K, Bui D, Lin H, Huang Y, Li Y, Rajeevan N, Maciejewski M, Smith V, Bohnert A, Hynes D, Aslan M, Ioannou G. Impact of time zero designation on estimated COVID-19 antiviral effectiveness in observational studies. American Journal Of Epidemiology 2025, 195: 562-568. PMID: 41078178, DOI: 10.1093/aje/kwaf221.Peer-Reviewed Original ResearchCitationsAltmetricMetabolomic biomarkers of rest-activity rhythms in older women: results from the Women’s Health Initiative study
Zhang L, Yeung C, Lee K, Shadyab A, LaCroix A, Stone K, Yaffe K, Hayden K, Casanova R, Rapp S, Chen J, Baker L, Manson J, Huang Y, Xiao Q. Metabolomic biomarkers of rest-activity rhythms in older women: results from the Women’s Health Initiative study. Sleep 2025, 49: zsaf320. PMID: 41071097, PMCID: PMC12795739, DOI: 10.1093/sleep/zsaf320.Peer-Reviewed Original ResearchCitationsAltmetric
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300 George Street
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Fl 5th , Ste Ste 511
New Haven, CT 06511