Siqi Zhang
Associate Research ScientistCards
About
Research
Publications
2025
Short-term exposure to ambient temperature variability and myocardial infarction hospital admissions: A nationwide case-crossover study in Sweden
Ni W, Stafoggia M, Zhang S, Ljungman P, Breitner S, de Bont J, Jernberg T, Atar D, Schneider A, Agewall S. Short-term exposure to ambient temperature variability and myocardial infarction hospital admissions: A nationwide case-crossover study in Sweden. PLOS Medicine 2025, 22: e1004607. PMID: 40392899, PMCID: PMC12091774, DOI: 10.1371/journal.pmed.1004607.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionNon-ST-segment elevation myocardial infarctionAssociated with increased riskHospital admissionAssociated with increased risk of hospital admissionElevation myocardial infarctionHospitalization riskRisk of hospital admissionConditional logistic regression modelsPopulation-based nationwide studyMyocardial infarctionShift exposureCase-crossover designPotential effect modifiersCase-crossover studyAssociated with decreased riskPatient's residential areaTemperature variabilityLogistic regression modelsNo significant associationHistory of diseaseTime-stratifiedMI hospitalizationSWEDEHEART registryClimate changeAir pollution and stroke: Short-term exposure's varying effects on stroke subtypes
Liao M, Zhang S, He C, Breitner S, Cyrys J, Naumann M, Braadt L, Traidl-Hoffmann C, Hammel G, Peters A, Ertl M, Schneider A. Air pollution and stroke: Short-term exposure's varying effects on stroke subtypes. Ecotoxicology And Environmental Safety 2025, 298: 118296. PMID: 40373710, DOI: 10.1016/j.ecoenv.2025.118296.Peer-Reviewed Original ResearchConceptsAir pollutionParticulate matterShort-term air pollution exposureAir pollution exposureSpecific air pollutantsShort-term exposureAverage air pollutionContext of global warmingPolluted areasMonitoring sitesPollution exposureCase-crossover studyAerodynamic diameterPollutionCoarse particlesFine particlesWarm seasonNitrogen oxidesGlobal warmingMeteorological dataStroke subtypesSouthern GermanyStroke eventsConditional logistic regressionPre-existing disabilityLow and high air temperature and cardiovascular risk
Ni W, Areal A, Lechner K, Breitner S, Zhang S, Woeckel M, Slesinski S, Nikolaou N, Dallavalle M, Schikowski T, Schneider A. Low and high air temperature and cardiovascular risk. Atherosclerosis 2025, 406: 119238. PMID: 40383648, DOI: 10.1016/j.atherosclerosis.2025.119238.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseArea-level factorsRisk factorsIndividual-level measuresPre-existing cardiovascular diseasePopulation healthCardiovascular healthCardiovascular mortalityPublic healthHealthJ-shapedEpidemiological dataCardiovascular riskBiological plausibilityRiskAir pollutionAssociationPopulationMortalityClimate changeExtremitiesIndividual-Social dimensions of climate changeDiseaseDimensions of climate changeStroke risk associated with cold spells occurring during the warm season
He C, Breitner S, Zhang S, Naumann M, Traidl-Hoffmann C, Hammel G, Peters A, Ertl M, Schneider A. Stroke risk associated with cold spells occurring during the warm season. Environment International 2025, 199: 109514. PMID: 40328088, DOI: 10.1016/j.envint.2025.109514.Peer-Reviewed Original ResearchConceptsCold spellsStroke riskStroke casesWarm seasonOdds ratioCold spell definitionsCase-crossover studyConditional logistic regressionFrequency of extreme cold eventsRisk of stroke occurrenceElevated risk of strokeCumulative odds ratioClimate changeCold spell eventExtreme cold eventsIncreased stroke riskAir temperature thresholdsRisk of strokeCardiovascular healthStratified analysisOccurrence of strokeCity of AugsburgDaily mean temperatureElevated riskLogistic regressionShort‐Term Associations Between Ambient Ozone and Acute Myocardial Infarction Onset Among Younger Patients: Results From the VIRGO Study
Zhang S, Chu L, Lu Y, Wei J, Dubrow R, Chaudhry S, Spatz E, Krumholz H, Chen K. Short‐Term Associations Between Ambient Ozone and Acute Myocardial Infarction Onset Among Younger Patients: Results From the VIRGO Study. GeoHealth 2025, 9: e2024gh001234. PMID: 39968338, PMCID: PMC11833228, DOI: 10.1029/2024gh001234.Peer-Reviewed Original ResearchAcute myocardial infarction subtypeShort-term associationsAcute myocardial infarctionAcute myocardial infarction onsetAMI riskEffect modificationAssociated with increased AMI riskParticipant's home addressNon-Hispanic blacksNon-ST-segment elevation acute myocardial infarctionNon-Hispanic whitesCase-crossover designType 1 AMIConditional logistic regressionIncreased AMI riskMyocardial infarction onsetType 2 AMIAcute myocardial infarction patientsST-segment elevation acute myocardial infarctionLifestyle factorsSociodemographic statusHome addressUS hospitalsStratified analysisSpatiotemporal deep learning approach
2024
Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study
Liao M, Zhang S, Wolf K, Bolte G, Laxy M, Schwettmann L, Peters A, Schneider A, Kraus U. Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study. International Journal Of Hygiene And Environmental Health 2024, 264: 114513. PMID: 39719813, DOI: 10.1016/j.ijheh.2024.114513.Peer-Reviewed Original ResearchConceptsSelf-perceived healthLong-term air pollution exposureSelf-perceived health statusAir pollution exposurePoor SRHHealth statusAssociated with poor self-perceived healthPoor self-perceived healthPollution exposureInterquartile rangeLand-use regression modelsLogistic regressionGeocoded residential addressesParticle number concentrationFace-to-face interviewsCooperative Health ResearchEQ-5D index valueSelf-perceived stressAmbient air pollutionEQ-VAS scoresIQR increaseAir pollutionCross-sectional studyBody mass indexMultinomial logistic regressionShort-term effects of temperature and air pollution on mortality in Norway: a nationwide cohort-based study
Rao S, Zhang S, Ahimbisibwe A, Bekkevold T, Di Ruscio F, Palomares A, Frohn L, Geels C, Fernández L, Schneider A. Short-term effects of temperature and air pollution on mortality in Norway: a nationwide cohort-based study. Frontiers In Environmental Health 2024, 3: 1419261. DOI: 10.3389/fenvh.2024.1419261.Peer-Reviewed Original ResearchNatural-cause mortalityCause-specific mortalityPotential effect modificationLevels of air pollutionAir pollutionEffect modificationCardiovascular mortalityIncreased risk of respiratory mortalityIncreased riskRisk of respiratory mortalityConditional logistic regression modelsConcentrations of fine particulate matterHistory of cardiovascular diseaseElevated air pollution levelsCase-crossover studyRisk of cardiovascular mortalityRegression modelsIncreased risk of cardiovascular mortalityShort-term associationsFine particulate matterAir pollutant concentrationsCohort-based studyAir pollution levelsSubgroup of participantsLogistic regression modelsShort-term effects of ambient temperature variability on myocardial infarction hospitalizations in Sweden: A nationwide case-crossover study
Ni W, Stafoggia M, Zhang S, Ljungman P, Breitner S, Bont J, Jernberg T, Atar D, Schneider A, Agewall S. Short-term effects of ambient temperature variability on myocardial infarction hospitalizations in Sweden: A nationwide case-crossover study. European Heart Journal 2024, 45: ehae666.3605. DOI: 10.1093/eurheartj/ehae666.3605.Peer-Reviewed Original ResearchNon-ST-segment elevation myocardial infarctionCase-crossover studyST-segment elevation myocardial infarctionMI hospitalizationHome addressSWEDEHEART registryShort-term effectsElevation myocardial infarctionTemperature variabilityConditional logistic regression modelsPopulation-based nationwide studyAssessed potential effect modificationPatient's home addressMyocardial infarction hospitalizationsPotential effect modificationMyocardial infarctionEffects of temperature variabilityCase-crossover designAssociated with decreased riskSeven-day averageAssociated with increased riskNationwide SWEDEHEART registryLogistic regression modelsClimate changeEffect modificationEffect modification of air pollution on the association between heat and mortality in five European countries
Zhang S, Breitner S, Stafoggia M, Donato F, Samoli E, Zafeiratou S, Katsouyanni K, Rao S, Diz-Lois Palomares A, Gasparrini A, Masselot P, Nikolaou N, Aunan K, Peters A, Schneider A. Effect modification of air pollution on the association between heat and mortality in five European countries. Environmental Research 2024, 263: 120023. PMID: 39293751, DOI: 10.1016/j.envres.2024.120023.Peer-Reviewed Original ResearchHigh PM levelsEffect modificationAir pollutionHeat-related mortalityEffect modification of air pollutantsPM levelsRural dataHighest O3 level waDaily non-accidental deathsPotential effect modificationMixed-effects meta-regressionRandom-effects meta-analysisAttica region of GreecePoisson regression modelsHeat-mortality associationsAir pollutant concentrationsAir pollution levelsImprove air qualityTime-series studyHeat-related mortality riskHeat-related health impactsNon-accidental deathsSmall area dataTemperature-mortality relationshipPollutant concentrationsHeat and cause-specific cardiopulmonary mortality in Germany: a case-crossover study using small-area assessment
Zhang S, Breitner S, de' Donato F, Stafoggia M, Nikolaou N, Aunan K, Peters A, Schneider A. Heat and cause-specific cardiopulmonary mortality in Germany: a case-crossover study using small-area assessment. The Lancet Regional Health - Europe 2024, 46: 101049. PMID: 39290807, PMCID: PMC11406445, DOI: 10.1016/j.lanepe.2024.101049.Peer-Reviewed Original ResearchCase-crossover studyRelative riskImprove public health practiceConditional quasi-Poisson regressionAssociated with increased mortality riskPublic health practiceRandom-effects meta-analysisQuasi-Poisson regressionHeat-related health impactsDistrict-level characteristicsSmall area dataHealth practicesRespiratory mortalityAssociated with increased mortalityPotential individual-Cardiopulmonary mortalityMortality riskRespiratory deathsSub-causesVulnerability factorsMeta-RegressionHealth impactsRural areasMeta-analysisSubgroup analysis
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