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Heather Allore, PhD

Professor of Medicine (Geriatrics) and of Biostatistics; Leader, Data Management and Statistics Core, Yale Alzheimer's Disease Research Center, Internal Medicine; Co-director of the Biostatistics and Bioinformatics Core of the Yale Transdisciplinary Collaborative Center for Precision Medicine focused on Health Disparities, Yale Transdisciplinary Collaborative Center for Precision Medicine ; Associate Director of Gerontologic Biostatistical Methods, Internal Medicine: Geriatrics; Senior Biostatistician and Epidemiologist, Internal Medicine: Rheumatology; Co-Director of Biostatistical Core, Internal Medicine: Geriatrics

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Heather Allore, PhD

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The focus of my research collaborations and methodological development work as previous Director of Biostatistics at the Yale Program on Aging for 12 years and current Leader of the Yale Alzheimer's Disease Research Center's Data Management and Statistics Core. I founded the field of Gerontological Biostatistic. I lead the Design and Statistics Core of Imbedded Pragmatic Alzheimer’s Disease and AD-Related Dementias Clinical Trials Collaboratory. I am Co-director of the Biostatistics and Bioinformatics Core of the Yale Transdisciplinary Collaborative Center for Precision Medicine focused on Health Disparities, especially adults with multiple chronic conditions. I co-authored a paper on health disparities in the Decadal Survey of Behavioral and Social Science Research on Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias. My innovated analytic methods include joint trajectories of cognition, function and mortality. Innovative designs and biostatistical methods are required to rigorously address the myriad of unanswered scientific questions related to older adults and persons with dementia, including risk prediction.

With over 240 peer-reviewed articles and continuous NIH funding since 2000, my research has focused on issues related to the design of clinical trials for and studies of older adults. These and other methodologic advances resulted in me being an invited speaker at an NIH/NIA conference on Longitudinal Methods and another on Clinical Trial Design. In 2017 and 2020, I co-chaired the Study Design and Metrics component of the NIH meeting on the 21st Century Cures Act: Inclusion Across the Lifespan I and II. I previously chaired the Alzheimer's Disease Research Center's Data Cores Steering Committee, member of the Executive Committee, and Co-Lead of the Data and Measures Committee of the NIA-funded AGING Initiative, which is a collaboration of Older Americans Independence Centers and the Healthcare Systems Research Network. I have a wealth of experience conducting epidemiologic studies and am a recognized authority on longitudinal statistical methods, including extended Cox models for state transitions, generalized estimating equations, mixed effects models, latent class trajectory models, and joint models. A defining hallmark of my biostatistical approach is that instead of developing analytic methods in the absence of a clinical question or adapting the study question to available analytical techniques, I adapt new statistical methods that suitably model the specific study question.

Education & Training

  • Postdoctoral Fellow
    Cornell University (1999)
  • PhD
    Cornell University (1996)
  • MSc
    Cornell University (1993)
  • BS (Hon)
    State University of New York, College of Technology, Computer Science (1989)


  • Keynote for “Healthy Aging and Geriatrics Forum: China Health Policy and Management Society Session”, a Virtual Workshop Xi’an, China.
    Global Health International Congress, Keynote for “Healthy Aging and Geriatrics Forum: China Health Policy and Management Society Session”, a Virtual Workshop Xi’an, China. 2022
    Global Health International Congress
  • Calculating Additive Contributions of Dementia and Chronic Conditions to Hospitalization, SNF Admission and Mortality: Why Race Matters
    Durham, NC, United States 2022
    Workshop: Leveraging Existing Data and Analytic Methods for Health Disparities Research Related to Aging
  • “Inclusion/ exclusion Criteria in Trial Design”
    Hosted by the National Academies of Sciences, Engineering and Medicine 2020
    National Academies of Sciences, Engineering and Medicine, Drug Research and Development for Adults Across the Older Age Span
  • Data analysis and study interpretation
    Due to pandemic this was held virtually 2020
    National Institutes of Health, Inclusion Across the Lifespan-II Workshop: Implementation and Future Directions
  • Brain Health and Aging
    Christchurch, Canterbury, New Zealand 2020
    Knowledge Exchange 2020: Good for the Brain Good for Life Symposium
  • Research Gaps for Long-Term Drug Therapies for Osteoporotic Fracture Prevention
    Sydney, NSW, Australia 2020
    University of Sydney Australia, Department of Pharmacy
  • Collaboration
    Amsterdam, NH, Netherlands; Portland, OR, United States; Ann Arbor, MI, United States; Boston, MA, United States; Providence, RI, United States 2018
    Working with researchers on caregiving and alternatives to hospitalization for older adults
  • Sabbatical and Visiting Professor Research
    Christchurch, Canterbury, New Zealand; Sydney, NSW, Australia; Trondheim, Trøndelag, Norway; Bergen, Vestland, Norway (2017-2020)
    Worked with aging researchers
  • Sabbatical
    Sydney, NSW, Australia; Bergen, Hordaland, Norway (2016-2017)
  • Vice President
    Guilford, Connecticut, United States (2009-2014)
    Guilford Land Conservation Trust

Honors & Recognition

AwardAwarding OrganizationDate
FellowGerontological Society of America2016
Women’s Midcareer Leadership Competitive ApplicationAmerican Association of Medical Colleges2014
Paul Harris FellowRotary International2012
NRI Competitive Grants Postdoctoral Fellowship 96-35204-3441NRI Competitive Grants Postdoctoral Fellowship1996
Gamma Sigma Delta Research AwardGamma Sigma Delta, Honor Society1991
HR Anslie Leadership AwardCornell University1990

Professional Service

Alzheimer’s Disease Centers Data Core Steering CommitteeLead the ADRC's Data Cores Steering Committee. Created Mission Statement, started and organized webinars and annual fall meeting and pre-meeting Analytics Workshop.2019 - 2021
American Geriatrics AssociationStatistical AE2018 - Present
Gerontologic Society of AmericaStatistical Editor2015 - Present
NIHSpecial Emphasis Panel Reviewer, Support of Competitive Research (SCORE)2015 - Present
American College of RheumatologyStatistical Editor2015 - Present
International Journal of Statistics in Medical ResearchSpecial Issue “Methods for Estimating Treatment Effects for Persons with Multiple Chronic Conditions” 2015 - Present
Gerontological Society of AmericaHealth Sciences Membership Committee2014 - 2017
NIH/NIAPPG P01Alzheimer’s Disease2014 - Present
NIH/NIAClinical Trial Advisory Panel2014 - Present
NIH/NIAIDSEP Reviewer, P01 Immunology, NIH/NIAID2011 - 2012
NIH/NIAIDSEP Immunology,2011 - 2012
NIMHMember, Special Emphasis Panel, Treatment of Mental Illness2009 - 2010
Foundation for NIH review panel on SarcopeniaReview panel on Sarcopenia2009
Gerontological Society of AmericaConvener Gerontological Society of America Measures Statistics Research Design Section2008 - 2010
CDCChair: CDC Special Emphasis Panel: Preparing People with Arthritis to Safely Select and Self Direct their Physical Activity2008 - Present
CDCCDC Mentored Public Health Research Scientist Development Award2007
NIH/NIANIH/NIA ASG Study Section2006 - 2012
Human Nutrition and Obesity Section USDA-NRICGPHuman Nutrition and Obesity Section USDA-NRICGP2006 - Present
USDA Small Business Initiative Grant ProgramUSDA Small Business Initiative Grant Program2003 - 2005
VA Cooperative Studies Program Coordinating CenterVA Cooperative Studies Program Coordinating Center Human Rights Committee2002 - Present

Departments & Organizations