In her first semester in the Master of Public Health program, Trisha Ramsdell discovered that she really missed the lab. However, with some well-timed advising, she soon learned that epidemiology and microbiology are well paired for understanding how infectious diseases spread.
Since then, Trisha’s home away from home has been in Professor Christian Tschudi’s lab, where she studies trypanosomes, the unicellular parasites that are the causative agent of African trypanosomiasis, commonly known as sleeping sickness. This microbiological approach to further understanding the parasite is important to population health as both people and livestock in sub-Saharan Africa are exposed to the disease through the bites of infected tsetse flies. Trisha’s thesis applies the relatively new technology of single cell-RNA sequencing to the parasite to characterize differences amongst singular cells as they progress through development to their infectious stage.