covidestim: A Vital Tool for Pandemic Response
Project Summary
covidestim was a real-time modeling tool developed by epidemiologists from the Yale School of Public Health and the Harvard T.H. Chan School of Public Health, with computational support from the Yale Center for Research Computing. During its operation, the tool provided up-to-date COVID-19 metrics across the United States on a county-by-county and state-by-state basis, including estimated infection rates, the effective case reproduction number, and estimated seroprevalence.
Designed for both public health officials and the public, covidestim offered critical insights for government officials and health leaders to help make informed decisions about public health interventions.
The tool operated until its shutdown in January 2024 and remains freely available on the covidestim website. All data and estimates over the entire pandemic have been stored and are freely and publicly available in the Harvard Dataverse.
Research Methodology
Critically, covidestim focused on "nowcasting"—providing a clearer understanding of the current state of the pandemic rather than projecting future trends, using sophisticated epidemiological models and statistical reasoning. The model addressed several challenges in real-time tracking, such as asymptomatic cases, delays in reporting symptomatic cases, and inconsistencies in cases, hospitalization and death reporting, to develop the most accurate snapshots of the pandemic possible.
During its operation, the covidestim models were initially updated daily (and later weekly), providing a glimpse into the pandemic’s progression through time and across counties and states. The tool revealed key trends, including the geographic heterogeneity of infection rates, with hotspots emerging in different regions at different times. Its findings helped visualize the wave-like behavior of the pandemic.
Impact on Public Health
covidestim had a profound impact on public health planning during the pandemic. The tool was utilized by academic institutions and government bodies, including Yale University, which relied on state-level projections at the start of the academic semester. Some policymakers involved with Connecticut’s reopening plan also used covidestim to track county-level infection trends. The tool’s ability to offer real-time insights helped shape public health interventions and assess their effectiveness.
Though covidestim is no longer being updated, its influence on public health decision-making during the pandemic was significant. The team behind the tool made their code and estimates freely available, encouraging others to build on their work and further advance public health preparedness for future outbreaks.
Project Contributors
Melanie H. Chitwood, Ted Cohen, Kenneth Gunasekera, Joshua Havumaki, Fayette Klaassen, Nicolas A. Menzies, Virginia E. Pitzer, Marcus Russi, Joshua Salomon, Nicole Swartwood, Joshua L. Warren, and Daniel M. Weinberger.
Press Coverage
- Estimated Covid infections may be 5 times higher than official counts, researchers project— VT Digger, August 1, 2022
- More people are getting reinfected with COVID-19— The Day, July 30, 2022
- Ron DeSantis can’t figure out who made covid all political— The Washington Post, October 28, 2021
- COVID-19 testing rates have dropped in CT. Do we have a handle on the spread of the delta variant?— CT Mirror, August 12, 2021
Research Publications
- Combining genomic data and infection estimates to characterize the complex dynamics of SARS-CoV-2 Omicron variants in the US.Lopes R, Pham K, Klaassen F, Chitwood MH, Hahn AM, Redmond S, Swartwood NA, Salomon JA, Menzies NA, Cohen T, Grubaugh ND. Cell Rep. 2024 Jul 23; 2024 Jul 5. PMID: 38970788.
- Predictive power of wastewater for nowcasting infectious disease transmission: A retrospective case study of five sewershed areas in Louisville, Kentucky.Klaassen F, Holm RH, Smith T, Cohen T, Bhatnagar A, Menzies NA. Environ Res. 2024 Jan 1; 2023 Oct 12. PMID: 37838198.
- Changes in Population Immunity Against Infection and Severe Disease From Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variants in the United States Between December 2021 and November 2022.Klaassen F, Chitwood MH, Cohen T, Pitzer VE, Russi M, Swartwood NA, Salomon JA, Menzies NA. Clin Infect Dis. 2023 Aug 14. PMID: 37074868.
- Population Immunity to Pre-Omicron and Omicron Severe Acute Respiratory Syndrome Coronavirus 2 Variants in US States and Counties Through 1 December 2021.Klaassen F, Chitwood MH, Cohen T, Pitzer VE, Russi M, Swartwood NA, Salomon JA, Menzies NA. Clin Infect Dis. 2023 Feb 8. PMID: 35717642.
- Changes in population immunity against infection and severe disease from SARS-CoV-2 Omicron variants in the United States between December 2021 and November 2022.Klaassen F, Chitwood MH, Cohen T, Pitzer VE, Russi M, Swartwood NA, Salomon JA, Menzies NA. medRxiv. 2022 Nov 23; 2022 Nov 23. PMID: 36451882.
- Reconstructing the course of the COVID-19 epidemic over 2020 for US states and counties: Results of a Bayesian evidence synthesis model.Chitwood MH, Russi M, Gunasekera K, Havumaki J, Klaassen F, Pitzer VE, Salomon JA, Swartwood NA, Warren JL, Weinberger DM, Cohen T, Menzies NA. PLoS Comput Biol. 2022 Aug; 2022 Aug 30. PMID: 36040963.
Project Funding
This project was supported by Cooperative Agreement NU38OT000297 from the Centers for Disease Control and Prevention (CDC) and the Council of State and Territorial Epidemiologists (CSTE), SHEPheRD Contract 200-2016-91779 from the CDC, and the CDC Broad Agency Announcement Contract 75D30122C14697.