Social isolation and likelihood of becoming centenarians: evidence from the Chinese longitudinal healthy longevity survey
Li Y, Jigeer G, Lv Y, Wang K, Peng Y, Sun L, Shi X, Gao X. Social isolation and likelihood of becoming centenarians: evidence from the Chinese longitudinal healthy longevity survey. BMC Geriatrics 2024, 24: 839. PMID: 39407128, PMCID: PMC11476547, DOI: 10.1186/s12877-024-05417-z.Peer-Reviewed Original ResearchConceptsChinese Longitudinal Healthy Longevity SurveySocial isolationLongevity SurveyAssociated with health outcomesHigher social isolation scoresConditional logistic regression modelsOldest-old peopleProspective nested case-control studyPublic health initiativesSocial isolation scoresOldest-old populationNested case-control studyDegree of social isolationLogistic regression modelsCase-control studyBackgroundSocial isolationHealth initiativesHealth outcomesLifestyle factorsCommunity-basedNever smokersOlder adultsYear of entryInverse associationIsolation scoresExposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study.
Ding E, Deng F, Fang J, Liu J, Yan W, Yao Q, Miao K, Wang Y, Sun P, Li C, Liu Y, Dong H, Dong L, Zhang X, Lu Y, Lin X, Ding C, Li T, Shi Y, Cai Y, Liu X, Godri Pollitt K, Ji J, Tong S, Tang S, Shi X. Exposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study. Environmental Health Perspectives 2024, 132: 97005. PMID: 39240788, PMCID: PMC11379127, DOI: 10.1289/ehp13864.Peer-Reviewed Original ResearchConceptsDyslipidemia markersCardiovascular diseaseMulti-omicsMarkers of dyslipidemiaExamination of cytokinesMeasurement of cytokinesSerum lipidomeSystemic inflammationMulti-omics profilingCardiac functionDyslipidemiaPrimary preventionClinical measuresSerumChinese adultsBlood transcriptomeImpact spectraCytokinesExposome-wide association studyInflammationMarkersBiomolecular pathwaysAssociationHealthy older adultsElectrocardiogramAssociation between dietary diversity changes and frailty among Chinese older adults: findings from a nationwide cohort study
Wang X, Zhong W, Zhang Y, Xiang J, Chen H, Li Z, Shen Q, Shen D, Song W, Fu Q, Gao J, Chen Z, Li C, Xie J, Liu D, Lv Y, Shi X, Mao C. Association between dietary diversity changes and frailty among Chinese older adults: findings from a nationwide cohort study. Nutrition Journal 2024, 23: 91. PMID: 39138490, PMCID: PMC11320915, DOI: 10.1186/s12937-024-00997-3.Peer-Reviewed Original ResearchConceptsDietary diversity scoreRisk of frailtyChinese older adultsOlder adultsSelf-reported health itemsChinese Longitudinal Healthy Longevity SurveyHigher risk of frailtyIncreased risk of frailtyOlder Chinese adultsFollow-up surveyNationwide cohort studyCox proportional hazards modelsHealth itemsLongevity SurveyFrailty incidencePrevent frailtyProportional hazards modelBackgroundDietary diversityChinese adultsFood groupsAssess frailtyPotential preventive measuresDiversity scoreComparing scoresCohort studyAssociation between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study
Sun P, Guo X, Ding E, Li C, Ren H, Xu Y, Qian J, Deng F, Shi W, Dong H, Lin E, Guo P, Fang J, Zhang Q, Zhao W, Tong S, Lu X, Pollitt K, Shi X, Tang S. Association between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study. Environmental Health Perspectives 2024, 132: 077005. PMID: 39028628, PMCID: PMC11259245, DOI: 10.1289/ehp13865.Peer-Reviewed Original ResearchConceptsFat mass indicatorsHealthy older adultsBayesian kernel machine regressionVisceral fat areaOlder adultsPercent body fatBody compositionBody fat massExposome-wide association studyPrevention of chronic diseasesAir pollution exposureBody composition indicatorsMediation analysisInBody 770 deviceHealthy adultsAssociated with increased body fat massBody composition changesKernel machine regressionBayesian kernel machine regression modelsChronic diseasesPollution exposureBody fatAssociation studiesAdverse health effectsFat area[Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China].
Zhou J, Qi L, Wang J, Liu S, Shi W, Ye L, Zhang Z, Zhang Z, Meng X, Cui J, Chen C, Lyu Y, Shi X. [Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China]. Chinese Journal Of Epidemiology 2024, 45: 809-816. PMID: 38889980, DOI: 10.3760/cma.j.cn112338-20231205-00333.Peer-Reviewed Original ResearchConceptsDaily living scoresPredictors of frailtyArea under the receiver operating characteristic curveIncident frailtyOlder adultsLiving scoresChinese Longitudinal Healthy Longevity SurveyRisk thresholdSelf-rated healthChinese older adultsRisk of incident frailtyRisk of frailtyFree of frailtyPhysical examination variablesCox proportional hazards regression modelsProportional hazards regression modelsRisk prediction modelInstrumental activitiesHazards regression modelsLongevity SurveyFrailty incidenceFollow-up timeDecision-curve analysisOlder personsReceiver operating characteristic curveHealthy Lifestyle and the Likelihood of Becoming a Centenarian
Li Y, Wang K, Jigeer G, Jensen G, Tucker K, Lv Y, Shi X, Gao X. Healthy Lifestyle and the Likelihood of Becoming a Centenarian. JAMA Network Open 2024, 7: e2417931. PMID: 38900423, PMCID: PMC11190803, DOI: 10.1001/jamanetworkopen.2024.17931.Peer-Reviewed Original ResearchConceptsHealthy lifestyleCase-control studyLifestyle factorsOlder adultsChinese Longitudinal Healthy Longevity SurveySelf-reported chronic conditionsHealthy lifestyle scoreImprove lifestyle behaviorsChinese older adultsAssociated with life expectancyProspective nested case-control studyNested case-control studyLifestyle scoreLifestyle behaviorsLongevity SurveyOlder age groupsHealth outcomesChronic conditionsSociodemographic characteristicsCommunity-basedMental wellnessYear of entryMain OutcomesOdds ratioMiddle-agedAssociations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study
Xing Y, Li Z, Wang J, Qu Y, Hu Q, Ji S, Chang X, Zhao F, Lv Y, Pan Y, Shi X, Dai J. Associations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study. Environment International 2024, 184: 108459. PMID: 38320373, DOI: 10.1016/j.envint.2024.108459.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesBayesian kernel machine regressionNationally representative cross-sectional studyNonlinear dose-response associationDose-response associationChinese adult populationWeighted multiple linear regressionGeneral Chinese populationCross-sectional studyNationally representative dataYounger age groupsKernel machine regressionChinese adultsInverse associationG-computationPerfluoroheptane sulfonic acidQuantile-based g-computationAdult populationRepresentative dataSignificant associationPositive associationThyroid homeostasisChinese populationMultiple linear regressionAge groups[Association of sleep duration and physical exercise with dyslipidemia in older adults aged 80 years and over in China].
Wu B, Li Y, Xu L, Zhang Z, Zhou J, Wei Y, Chen C, Wang J, Wu C, Li Z, Hu Z, Long F, Wu Y, Hu X, Li K, Li F, Luo Y, Liu Y, Lyu Y, Shi X. [Association of sleep duration and physical exercise with dyslipidemia in older adults aged 80 years and over in China]. Chinese Journal Of Epidemiology 2024, 45: 48-55. PMID: 38228524, DOI: 10.3760/cma.j.cn112338-20231007-00207.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesPhysical exerciseSleep durationPerson yearsDose-response relationshipAssociation of sleep durationPositive dose-response relationshipImpact of sleep durationBlood lipid testRisk of dyslipidemiaAverage sleep durationRestricted cubic spline functionsCompeting risk modelBaseline surveyBiomarkers Cohort StudyCases of dyslipidemiaLipid testingFasting venous blood samplesInteraction of sleep durationCohort studyExerciseCompetitive risk model analysisDemographic characteristicsIncidence densityStudy subjects