Body mass index, waist circumference, and mortality in subjects older than 80 years: a Mendelian randomization study
Lv Y, Zhang Y, Li X, Gao X, Ren Y, Deng L, Xu L, Zhou J, Wu B, Wei Y, Cui X, Xu Z, Guo Y, Qiu Y, Ye L, Chen C, Wang J, Li C, Luo Y, Yin Z, Mao C, Yu Q, Lu H, Kraus V, Zeng Y, Tong S, Shi X. Body mass index, waist circumference, and mortality in subjects older than 80 years: a Mendelian randomization study. European Heart Journal 2024, 45: 2145-2154. PMID: 38626306, PMCID: PMC11212828, DOI: 10.1093/eurheartj/ehae206.Peer-Reviewed Original ResearchChinese Longitudinal Healthy Longevity SurveyHigher body mass indexAssociation of body mass indexBody mass indexNon-CVD mortalityOldest-old peopleWaist circumferenceOldest-oldMortality riskMendelian randomizationSingle-nucleotide polymorphismsInverse relationship of BMIStudies of body mass indexRelationship of body mass indexCardiovascular diseaseOptimal body mass indexMass indexAssociated with body mass indexCardiovascular disease mortalityMendelian randomization studiesAssociated with decreased mortality riskGenetic risk scoreNon-linear MR analysisLower mortality riskJoint effect analysis