Associations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study
Zheng X, Pan Y, Qu Y, Ji S, Wang J, Li Z, Zhao F, Wu B, Xie L, Li Y, Song H, Hu X, Qiu Y, Zhang Z, Zhang W, Yang Y, Cai J, Zhu Y, Zhu Y, Cao Z, Ji J, Lv Y, Dai J, Shi X. Associations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study. Environmental Science And Technology 2024, 58: 12875-12887. PMID: 38980177, DOI: 10.1021/acs.est.3c11095.Peer-Reviewed Original ResearchNationwide cross-sectional studyPublic health planningCross-sectional studyOdds of hyperuricemiaChinese adultsHealth plansJoint effectsElevated oddsGeneral populationNationwide studyNonmonotonic dose responsePositive associationRisk factorsAdultsHealthEffects of polyfluoroalkyl substancesHealth hazardsParticipantsSerum polyfluoroalkyl substancesJoint effects of PFAS mixtureMeasured serum concentrationsFish consumptionSerum concentrations of uric acidAssociationHyperuricemiaPositive Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Hypertension May Be Attenuated by Endogenous Sex Hormones: A Nationally Representative Cross-Sectional Study
Wu B, Sheng N, Li Z, Wang J, Ji S, Zhao F, Pan Y, Qu Y, Wei Y, Xie L, Li Y, Hu X, Wu C, Zhang Z, Qiu Y, Zheng X, Zhang W, Hu X, Song H, Cai J, Cao Z, Ji J, Lv Y, Dai J, Shi X. Positive Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Hypertension May Be Attenuated by Endogenous Sex Hormones: A Nationally Representative Cross-Sectional Study. Hypertension 2024, 81: 1799-1810. PMID: 38853753, DOI: 10.1161/hypertensionaha.123.22127.Peer-Reviewed Original ResearchDiastolic blood pressureSystolic blood pressureEndogenous sex hormonesBlood pressureNationally representative cross-sectional studyPositive associationPerfluoroheptane sulfonic acidWeighted multiple logistic regressionSex hormonesLevels of endogenous sex hormonesPrevalence of hypertensionCross-sectional studyMultiple logistic regressionAssociations of polyfluoroalkyl substancesPFAS mixtureJoint effects of PFAS mixtureAssociated with hypertensionProgression of hypertensionChinese adultsSynergy indexOdds ratioG-computationQuantile-based g-computationRisk ratioLogistic regressionAssociations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study
Xing Y, Li Z, Wang J, Qu Y, Hu Q, Ji S, Chang X, Zhao F, Lv Y, Pan Y, Shi X, Dai J. Associations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study. Environment International 2024, 184: 108459. PMID: 38320373, DOI: 10.1016/j.envint.2024.108459.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesBayesian kernel machine regressionNationally representative cross-sectional studyNonlinear dose-response associationDose-response associationChinese adult populationWeighted multiple linear regressionGeneral Chinese populationCross-sectional studyNationally representative dataYounger age groupsKernel machine regressionChinese adultsInverse associationG-computationPerfluoroheptane sulfonic acidQuantile-based g-computationAdult populationRepresentative dataSignificant associationPositive associationThyroid homeostasisChinese populationMultiple linear regressionAge groups