2018
Plasma Menthol Glucuronide as a Biomarker of Acute Menthol Inhalation
Jatlow P, Valentine G, Gueorguieva R, Nadim H, Wu R, O'Malley SS, Sofuoglu M. Plasma Menthol Glucuronide as a Biomarker of Acute Menthol Inhalation. Tobacco Regulatory Science 2018, 4: 586-591. PMID: 29479558, PMCID: PMC5822727, DOI: 10.18001/trs.4.1.5.Peer-Reviewed Original ResearchPlasma Mg concentrationHuman challenge studiesMenthol inhalationMenthol glucuronideMenthol exposureChallenge studiesAnti-irritant effectsDose-dependent increaseInhalation of aerosolsE-cigarette solutionsVenous plasmaVenous bloodIntravenous nicotineNicotine dependenceSecondary analysisInhalationE-cigarettesQuantitative biomarkersVulnerable populationsInter-individual differencesAfrican AmericansNicotineMenthol concentrationGlucuronideBiomarkers
2017
Studying the interactive effects of menthol and nicotine among youth: An examination using e-cigarettes
Krishnan-Sarin S, Green BG, Kong G, Cavallo DA, Jatlow P, Gueorguieva R, Buta E, O’Malley S. Studying the interactive effects of menthol and nicotine among youth: An examination using e-cigarettes. Drug And Alcohol Dependence 2017, 180: 193-199. PMID: 28915478, PMCID: PMC5659733, DOI: 10.1016/j.drugalcdep.2017.07.044.Peer-Reviewed Original ResearchConceptsAd lib useE-cigarettesE-cigarette usersStimulant effectsNicotine concentrationsNicotine-containing e-cigarettesNicotine withdrawal symptomsMenthol concentrationRandom counterbalanced orderPositive rewarding effectsNicotine exposureNicotine withdrawalWithdrawal symptomsRewarding effectsMenthol glucuronideHigh menthol concentrationLow dosesNicotine levelsTobacco productsNicotineCounterbalanced order