2006
Stress-Induced Cocaine Craving and Hypothalamic-Pituitary-Adrenal Responses Are Predictive of Cocaine Relapse Outcomes
Sinha R, Garcia M, Paliwal P, Kreek MJ, Rounsaville BJ. Stress-Induced Cocaine Craving and Hypothalamic-Pituitary-Adrenal Responses Are Predictive of Cocaine Relapse Outcomes. JAMA Psychiatry 2006, 63: 324-331. PMID: 16520439, DOI: 10.1001/archpsyc.63.3.324.Peer-Reviewed Original ResearchMeSH KeywordsAdrenocorticotropic HormoneAdultBehavior, AddictiveCocaine-Related DisordersCuesFemaleFollow-Up StudiesHospitalizationHumansHydrocortisoneHypothalamo-Hypophyseal SystemMaleMiddle AgedPituitary-Adrenal SystemProspective StudiesSecondary PreventionStress, PsychologicalSubstance Abuse Treatment CentersTreatment OutcomeConceptsAdrenal axis responseCocaine cravingRelapse outcomesAxis responseCocaine relapseAdrenal responseInpatient treatmentCocaine relapse outcomesCue-induced cocaine cravingStress-induced drug cravingCocaine useCocaine dependenceCox proportional hazards regressionCommunity mental health centerProportional hazards regressionMental health centersProspective study designDrug cue exposureStress-related increasesTreatment-seeking cocaine dependent individualsHazards regressionHypothalamic-PituitaryHealth centersCocaine-dependent individualsRelapse
1999
Naturalistic Follow-Up of Drinking Behavior Following Participation in an Alcohol Administration Study
Sinha R, Krishnan-Sarin S, Farren C, O'Malley S. Naturalistic Follow-Up of Drinking Behavior Following Participation in an Alcohol Administration Study. Journal Of Substance Use And Addiction Treatment 1999, 17: 159-162. PMID: 10435264, DOI: 10.1016/s0740-5472(98)00058-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingAlcoholismEthics, MedicalFemaleFollow-Up StudiesHuman ExperimentationHumansMaleMotivationPsychotherapy, BriefSecondary PreventionConceptsAlcohol administration researchAlcohol-dependent individualsSubsequent drinkingDrinking behaviorBrief motivational interventionAlcohol administration studyParticipants' drinking behaviorMotivational interventionIndividual motivationNumber of drinksAssessment of drinkingAdministration of alcoholAdministration researchSelf-administration studiesDrinking daysEffects of naltrexoneAlcohol dependenceParticipantsMotivationDrinkingIndividualsClinical benefitFollow-upBaseline levelsClinical need