2018
The Breast Cancer Weight Loss (BWEL) trial: Randomized phase III trial evaluating the role of weight loss in adjuvant treatment of overweight and obese women with early-stage breast cancer (Alliance A011401).
Ligibel J, Barry W, Alfano C, Hershman D, Irwin M, Neuhouser M, Thomson C, Delahanty L, Frank E, Spears P, Paskett E, Hopkins J, Bernstein V, Stearns V, White J, Wadden T, Goodwin P, Carey L, Partridge A, Winer E. The Breast Cancer Weight Loss (BWEL) trial: Randomized phase III trial evaluating the role of weight loss in adjuvant treatment of overweight and obese women with early-stage breast cancer (Alliance A011401). Journal Of Clinical Oncology 2018, 36: tps598-tps598. DOI: 10.1200/jco.2018.36.15_suppl.tps598.Peer-Reviewed Original Research
2012
Post diagnosis weight gain and the role of exercise in breast cancer survivors.
Sanft T, Alvarez-Reeves M, Irwin M. Post diagnosis weight gain and the role of exercise in breast cancer survivors. Journal Of Clinical Oncology 2012, 30: 9007-9007. DOI: 10.1200/jco.2012.30.15_suppl.9007.Peer-Reviewed Original ResearchBone mineral densityLean body massDual-energy X-ray absorptiometryBreast cancer survivorsUsual careCA survivorsObese womenCancer survivorsBody fatBody compositionPoor breast cancer outcomesWeight gainFavorable body composition changesNon-obese womenBreast cancer outcomesRole of exerciseEffects of exerciseMin/wkPhysical activity levelsBody composition changesX-ray absorptiometrySupervised exerciseExercise groupExercise interventionUC group
2010
Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial
Friedenreich C, Woolcott C, McTiernan A, Terry T, Brant R, Ballard-Barbash R, Irwin M, Jones C, Boyd N, Yaffe M, Campbell K, McNeely M, Karvinen K, Courneya K. Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial. International Journal Of Obesity 2010, 35: 427-435. PMID: 20820172, PMCID: PMC3061001, DOI: 10.1038/ijo.2010.147.Peer-Reviewed Original ResearchConceptsAerobic exercise interventionTotal body fatExercise interventionPostmenopausal womenFat areaBody fatGreater body fat lossSubcutaneous abdominal fat areaCurrent public health guidelinesIntra-abdominal fat areaSedentary postmenopausal womenAbdominal fat areaAerobic exercise programExercise five timesBody fat lossDual-energy X-ray absorptiometry measurementsBreast cancer riskVolume of exerciseMeasures of adiposityPublic health guidelinesComputerized tomography measurementsExercise groupObese womenAbdominal adiposityExercise program
2005
Changes in Body Fat and Weight After a Breast Cancer Diagnosis: Influence of Demographic, Prognostic, and Lifestyle Factors
Irwin ML, McTiernan A, Baumgartner RN, Baumgartner KB, Bernstein L, Gilliland FD, Ballard-Barbash R. Changes in Body Fat and Weight After a Breast Cancer Diagnosis: Influence of Demographic, Prognostic, and Lifestyle Factors. Journal Of Clinical Oncology 2005, 23: 774-782. PMID: 15681521, PMCID: PMC3000612, DOI: 10.1200/jco.2005.04.036.Peer-Reviewed Original ResearchConceptsBody fat changesBody fatBreast cancer diagnosisLifestyle factorsPhysical activityFat changesCancer diagnosisHigher disease stagePopulation-based studyBreast cancer recurrenceBreast cancer prognosisPercent body fatFirst yearLean womenObese womenBaseline visitPotential cofoundersDisease stageLifestyle StudyPostdiagnosis periodCancer recurrenceBreast cancerCancer prognosisFat lossYounger age
2000
Moderate-intensity physical activity and fasting insulin levels in women: the Cross-Cultural Activity Participation Study.
Irwin M, Mayer-Davis E, Addy C, Pate R, Durstine J, Stolarczyk L, Ainsworth B. Moderate-intensity physical activity and fasting insulin levels in women: the Cross-Cultural Activity Participation Study. Diabetes Care 2000, 23: 449-454. PMID: 10857933, DOI: 10.2337/diacare.23.4.449.Peer-Reviewed Original ResearchConceptsModerate-intensity physical activityCross-Cultural Activity Participation StudyInsulin levelsRace/ethnicityPhysical activityHigher cardiorespiratory fitness levelsPhysical activity scoreSports Medicine recommendationsCardiorespiratory fitness levelsMin/dayCentral obesityObese womenActivity scoreCardiorespiratory fitnessCaucasian womenMedicine recommendationsHigh riskAmerican CollegeMultiple linear regression analysisLinear regression analysisMET-minMET intensityDisease controlFitness levelPA records