Hippocampal Engrams and Contextual Memory
Vasudevan K, Hassell J, Maren S. Hippocampal Engrams and Contextual Memory. Advances In Neurobiology 2024, 38: 45-66. PMID: 39008010, DOI: 10.1007/978-3-031-62983-9_4.Peer-Reviewed Original ResearchConceptsContextual fear conditioningFear conditioningFear memoryRetrieval of contextual fear memoryRetrieval of aversive memoriesNeural substrates of memoryPost-traumatic stress disorderContextual fear memorySubstrate of memoryActivity-dependent taggingRetrieval of eventsAversive memoryEncoding contextStress disorderContextual stimuliNeural substratesMemory ensemblesHippocampal ensemblesNeuronal mechanismsContextual learningHippocampusMemoryFearRetrievalEncodingHigh-fat diet, microbiome-gut-brain axis signaling, and anxiety-like behavior in male rats
de Noronha S, de Moraes L, Hassell J, Stamper C, Arnold M, Heinze J, Foxx C, Lieb M, Cler K, Karns B, Jaekel S, Loupy K, Silva F, Chianca-Jr. D, Lowry C, de Menezes R. High-fat diet, microbiome-gut-brain axis signaling, and anxiety-like behavior in male rats. Biological Research 2024, 57: 23. PMID: 38705984, PMCID: PMC11071217, DOI: 10.1186/s40659-024-00505-1.Peer-Reviewed Original ResearchConceptsDefensive behavioral responsesSerotonergic gene expressionDorsal raphe nucleusSlc6a4 mRNA expressionBehavioral responsesMicrobiome-gut-brainRaphe nucleusAnxiety-related behavioral responsesBrain serotonergic systemSerotonergic brain systemAnxiety-like behaviorMale ratsAxis signalingHigh-fat dietBrain systemsSerotonergic systemAssociated with stressCommunity compositionGut microbiomeGene expressionAbundance of BlautiaHTR1AGut microbiome diversityTPH2SLC6A4