2023
Interrater reproducibility of the Myoton and durometer devices to quantify sclerotic chronic graft-versus-host disease
Ghosh S, Baker L, Chen F, Khera Z, Vain A, Zhang K, Hood A, Smith H, Chen H, Jagasia M, Tkaczyk E. Interrater reproducibility of the Myoton and durometer devices to quantify sclerotic chronic graft-versus-host disease. Archives Of Dermatological Research 2023, 315: 2545-2554. PMID: 37227518, DOI: 10.1007/s00403-023-02626-1.Peer-Reviewed Original ResearchConceptsSkin sclerosisChronic graftHost diseaseAnatomic sitesAllogeneic hematopoietic stem cell transplantationHematopoietic stem cell transplantationSclerotic chronic graftLong-term survivorsStem cell transplantationConfidence intervalsCGVHD treatmentSclerotic cGvHDSevere complicationsSkin scoreCurrent gold standardCell transplantationTherapeutic responseClinical reproducibilityCGVHDDorsal forearmMyotonSclerosisVolar forearmHealthy participantsMean pairwise difference
2019
Diagnostic Potential of Five Different Biomechanical Parameters to Detect Sclerotic Cutaneous Graft-Versus-Host Disease
Chen F, Wang L, Ssempijja Y, Vain A, Jagasia M, Tkaczyk E. Diagnostic Potential of Five Different Biomechanical Parameters to Detect Sclerotic Cutaneous Graft-Versus-Host Disease. Blood 2019, 134: 2002. DOI: 10.1182/blood-2019-129381.Peer-Reviewed Original ResearchCGVHD patientsBMT controlsCross-sectional studyHost diseaseSkin sclerosisSkin scoreBiomechanical parametersSclerotic patientsCutaneous Graft-VersusPost-BMT patientsMechanical stress relaxation timeHigh diagnostic yieldProspective longitudinal studyChronic graftGraft-VersusGVHD patientsSkin involvementUnaffected skinUnivariate analysisHealthy controlsMultivariate predictive modelClinician assessmentDiagnostic yieldTreatment responseResponse assessment