2023
Hyperspectral imaging to accurately segment skin erythema and hyperpigmentation in cutaneous chronic graft‐versus‐host disease
Saknite I, Kwun S, Zhang K, Hood A, Chen F, Kangas L, Kortteisto P, Kukkonen A, Spigulis J, Tkaczyk E. Hyperspectral imaging to accurately segment skin erythema and hyperpigmentation in cutaneous chronic graft‐versus‐host disease. Journal Of Biophotonics 2023, 16: e202300009. PMID: 36942511, DOI: 10.1002/jbio.202300009.Peer-Reviewed Original Research
2021
Optimal Biomechanical Parameters for Measuring Sclerotic Chronic Graft-Versus-Host Disease
Baker L, Chen F, Cronin A, Chen H, Vain A, Jagasia M, Tkaczyk E. Optimal Biomechanical Parameters for Measuring Sclerotic Chronic Graft-Versus-Host Disease. JID Innovations 2021, 1: 100037. PMID: 34790906, PMCID: PMC8594905, DOI: 10.1016/j.xjidi.2021.100037.Peer-Reviewed Original ResearchCGVHD patientsBiomechanical parametersChronic Graft-VersusSclerotic chronic graftHost disease patientsBackward stepwise selectionChronic graftGraft-VersusSclerotic cGvHDHost diseaseUnivariable analysisTransplant controlsDisease patientsAnatomic sitesPatientsDisease severityLogistic regressionSclerotic diseaseBiomechanical studyDiscriminatory abilityLASSO regressionCharacteristic curveMyotonometerStepwise selectionDisease
2019
Crowdsourcing to delineate skin affected by chronic graft‐vs‐host disease
Tkaczyk E, Coco J, Wang J, Chen F, Ye C, Jagasia M, Dawant B, Fabbri D. Crowdsourcing to delineate skin affected by chronic graft‐vs‐host disease. Skin Research And Technology 2019, 25: 572-577. PMID: 30786065, PMCID: PMC6719554, DOI: 10.1111/srt.12688.Peer-Reviewed Original ResearchConceptsChronic graftHost diseaseAffected skinPercent body surface areaBody surface areaBoard-certified dermatologistsCurrent clinical standardMedian Dice indexCGVHD patientsPrimary outcomeImportant unmetAffected surface areaThree-dimensional photographsClinical standardsFleiss' kappaDiseaseSkinGraftPractical managementWeak correlationHigh agreementKappaConsensus delineationPatients
2018
Non-invasive measurement of sclerosis in cutaneous cGVHD patients with the handheld device Myoton: a cross-sectional study
Chen F, Dellalana L, Gandelman J, Vain A, Jagasia M, Tkaczyk E. Non-invasive measurement of sclerosis in cutaneous cGVHD patients with the handheld device Myoton: a cross-sectional study. Bone Marrow Transplantation 2018, 54: 616-619. PMID: 30287938, PMCID: PMC6872187, DOI: 10.1038/s41409-018-0346-7.Peer-Reviewed Original ResearchSegmentation of skin lesions in chronic graft versus host disease photographs with fully convolutional networks
Wang J, Chen F, Dellalana L, Jagasia M, Tkaczyk E, Dawant B. Segmentation of skin lesions in chronic graft versus host disease photographs with fully convolutional networks. 2018, 10575: 105750n. DOI: 10.1117/12.2293334.Peer-Reviewed Original ResearchBody surface areaHematopoietic stem cell transplantationSkin lesionsChronic graftHost diseaseAllogeneic hematopoietic stem cell transplantationInvolved body surface areaSeverity of cGVHDLife-threatening complicationsStem cell transplantationCGVHD patientsCell transplantationPatient morbidityLesionsPatientsSerial photographyCGVHDGraftDiseaseSkinPreliminary studyEncouraging resultsMorbidityComplicationsTransplantation