2024
The Feasibility and Acceptability of a Clinical Pharmacist-delivered Intervention to Reduce Bothersome Health Symptoms from Polypharmacy and Alcohol Use and Communicate Risk among People with HIV: Pilot Study Protocol
Womack J, Leblanc M, Sager A, Zaets L, Maisto S, Garcia A, Aoun-Barakat L, Brown S, Edelman E, Fiellin D, Fisher J, Fraenkel L, Kidwai-Khan F, Marconi V, Martino S, Pulk R, Satre D, Virata M, Justice A, Hsieh E. The Feasibility and Acceptability of a Clinical Pharmacist-delivered Intervention to Reduce Bothersome Health Symptoms from Polypharmacy and Alcohol Use and Communicate Risk among People with HIV: Pilot Study Protocol. AIDS And Behavior 2024, 1-15. PMID: 39465468, DOI: 10.1007/s10461-024-04533-6.Peer-Reviewed Original ResearchUnhealthy alcohol useAlcohol usePharmacist-delivered interventionVeterans Aging Cohort StudyPilot study protocolStudy protocolElectronic health recordsSupport behavior changePre-test/post-test designAging Cohort StudySelf-administered surveyAlcohol use disorderAlcohol Research CenterBothersome symptomsPre-test/post-testCommunicating riskHealth recordsLong-term medicationHealth symptomsCounseling interventionCounseling sessionsSessions 2 weeksQualitative interviewsAlcohol consumptionUse disorderIntegrated stepped alcohol treatment with contingency management for unhealthy alcohol use among people with HIV: A randomized controlled trial.
Edelman E, Dziura J, Deng Y, DePhilippis D, Ferguson T, Brown S, Marconi V, Goetz M, Rodriguez-Barradas M, Simberkoff M, Molina P, Weintrob A, Maisto S, Paris M, Justice A, Bryant K, Fiellin D. Integrated stepped alcohol treatment with contingency management for unhealthy alcohol use among people with HIV: A randomized controlled trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2024 PMID: 39321757, DOI: 10.1097/qai.0000000000003534.Peer-Reviewed Original ResearchUnhealthy alcohol useSelf-reported abstinenceAlcohol useLost to follow-upContingency managementAlcohol use disorderRandomized controlled trialsSubstance use treatmentAlcohol abstinenceFollow-upUse disorderControlled trialsPWHAlcohol treatmentAbstinenceUse treatmentEvidence of abstinenceHIVWeeksMean proportionTreatmentTrialsAlcoholDaysParticipantsAssociations Between Reductions in Depressive Symptoms and Reductions in Pain and Anxiety Symptoms and Substance Use: Emulation of a Randomized Trial
Khan M, Acri M, Ban K, Scheidell J, Stevens E, Manandhar-Sasaki P, Charles D, Chichetto N, Crystal S, Gordon A, Marshall B, Edelman E, Justice A, Braithwaite S, Caniglia E. Associations Between Reductions in Depressive Symptoms and Reductions in Pain and Anxiety Symptoms and Substance Use: Emulation of a Randomized Trial. AJPM Focus 2024, 3: 100258. PMID: 39290574, PMCID: PMC11407062, DOI: 10.1016/j.focus.2024.100258.Peer-Reviewed Original ResearchUnhealthy alcohol useDepressive symptomsAnxiety symptomsIllicit opioid useOdds ratioAlcohol useVeterans Aging Cohort StudyPain symptomsConfidence intervalsTarget trial emulation frameworkElevated depressive symptomsAssociated with reductionsReducing depressive symptomsAging Cohort StudySubstance useOpioid useMultisite observational studyDepressive symptom reductionNext follow-up visitUS veteransReduce painFollow-up visitCohort studyAntidepressant medicationComparing individualsAlcohol-Related Care Among Veterans With Unhealthy Alcohol Use: The Role of Long-Term Opioid Therapy Receipt
Joudrey P, Wang M, DeRycke E, Williams E, Edelman E. Alcohol-Related Care Among Veterans With Unhealthy Alcohol Use: The Role of Long-Term Opioid Therapy Receipt. Journal Of Addiction Medicine 2024, 18: 293-299. PMID: 38533996, PMCID: PMC11150097, DOI: 10.1097/adm.0000000000001291.Peer-Reviewed Original ResearchUnhealthy alcohol useAlcohol-related careLong-term opioid therapyBrief interventionOpioid receiptAlcohol useReceipt of alcohol-related careReceipt of brief interventionVeterans Health Administration careRates of brief interventionDocumented brief interventionNational cohort of veteransWomen Veterans Cohort StudyCohort of veteransPositive alcohol screensAlcohol screeningIntervention receiptAdministration carePositive screenConsumption questionnaireOpioid prescribingNational cohortTherapy receiptCohort studyCarePerspectives of clinical stakeholders and patients from four VA liver clinics to tailor practice facilitation for implementing evidence-based alcohol-related care
Soyer E, Frost M, Fletcher O, Ioannou G, Tsui J, Edelman E, Weiner B, Bachrach R, Chen J, Williams E. Perspectives of clinical stakeholders and patients from four VA liver clinics to tailor practice facilitation for implementing evidence-based alcohol-related care. Addiction Science & Clinical Practice 2024, 19: 3. PMID: 38200496, PMCID: PMC10782537, DOI: 10.1186/s13722-023-00429-3.Peer-Reviewed Original ResearchConceptsConsolidated Framework for Implementation ResearchAlcohol-related careVeterans Health AdministrationRapid Assessment ProcessClinical stakeholdersPatient participationImplement interventionsBackgroundUnhealthy alcohol useLiver clinicEvidence-based strategiesClinical settingPractice facilitationProvider beliefsImplementation researchHealth AdministrationMethodsData collectionClinical resourcesQualitative interviewsAlcohol use disorderEducation-basedCareAlcohol useMedical CenterPreference-basedRelationship-based
2023
Perspectives on unhealthy alcohol use among men who have sex with men prescribed HIV pre-exposure prophylaxis: A qualitative study
Strong S, Oldfield B, van den Berg J, Cole C, Biegacki E, Ogbuagu O, Virata M, Chan P, Edelman E. Perspectives on unhealthy alcohol use among men who have sex with men prescribed HIV pre-exposure prophylaxis: A qualitative study. Preventive Medicine Reports 2023, 37: 102553. PMID: 38282665, PMCID: PMC10810836, DOI: 10.1016/j.pmedr.2023.102553.Peer-Reviewed Original ResearchUnhealthy alcohol usePre-exposure prophylaxisAlcohol reduction interventionsAlcohol useHIV pre-exposure prophylaxisOral pre-exposure prophylaxisAcquisition of HIVAlcohol-related harmPrEP adherencePrEP careTreatment optionsOral formulationReduction interventionsPrEP programMSMPrEPProphylaxisHIVMultimodal approachMenCareAdherenceInterventionSexUnited StatesPerspectives on contingency management for alcohol use and alcohol‐associated conditions among people in care with HIV
Cohen S, DePhilippis D, Deng Y, Dziura J, Ferguson T, Fucito L, Justice A, Maisto S, Marconi V, Molina P, Paris M, Rodriguez‐Barradas M, Simberkoff M, Petry N, Fiellin D, Edelman E. Perspectives on contingency management for alcohol use and alcohol‐associated conditions among people in care with HIV. Alcohol Clinical And Experimental Research 2023, 47: 1783-1797. PMID: 37524371, PMCID: PMC10828101, DOI: 10.1111/acer.15159.Peer-Reviewed Original ResearchUnhealthy alcohol useAlcohol useContingency managementPrimary care settingSubset of participantsReward structureEvidence-based approachHIV clinicImplementation science frameworkTreatment trialsClinical trialsIntervention feasibilityCare settingsPromoting ActionAlcohol consumptionRelated conditionsBiochemical testingClinical contextHIVReward schedulePatientsReward processesInterventionTrialsBehavior changeEfficacy of alcohol reduction interventions among people with HIV as evaluated by self-report and a phosphatidylethanol (PEth) outcome: protocol for a systematic review and individual participant data meta-analysis
Kane J, Allen I, Fatch R, Scheffler A, Emenyonu N, Puryear S, Chirayil P, So-Armah K, Kahler C, Magidson J, Conroy A, Edelman E, Woolf-King S, Parry C, Kiene S, Chamie G, Adong J, Go V, Cook R, Muyindike W, Morojele N, Blokhina E, Krupitsky E, Fiellin D, Hahn J. Efficacy of alcohol reduction interventions among people with HIV as evaluated by self-report and a phosphatidylethanol (PEth) outcome: protocol for a systematic review and individual participant data meta-analysis. BMJ Open 2023, 13: e070713. PMID: 37280036, PMCID: PMC10254608, DOI: 10.1136/bmjopen-2022-070713.Peer-Reviewed Original ResearchConceptsAlcohol useUnhealthy alcohol useSelf-reported measurementsAlcohol reduction interventionsEfficacy of interventionsAlcohol outcomesIndividual participant dataIntervention studiesAlcohol interventionsInformation biasesAdditional ethical approvalParticipants 15 yearsEffective interventionsSystematic reviewTreatment effectsParticipant dataHIV viral suppressionPrimary outcome variableReduction interventionsPooled treatment effectOutcome variablesInterventionInternational scientific meetingsSecondary outcomesViral suppressionContingency management with stepped care for unhealthy alcohol use among individuals with HIV: Protocol for a randomized controlled trial
Edelman E, Dziura J, Deng Y, DePhilippis D, Fucito L, Ferguson T, Bedimo R, Brown S, Marconi V, Goetz M, Rodriguez-Barradas M, Simberkoff M, Molina P, Weintrob A, Maisto S, Paris M, Justice A, Bryant K, Fiellin D. Contingency management with stepped care for unhealthy alcohol use among individuals with HIV: Protocol for a randomized controlled trial. Contemporary Clinical Trials 2023, 131: 107242. PMID: 37230168, PMCID: PMC10460633, DOI: 10.1016/j.cct.2023.107242.Peer-Reviewed Original ResearchConceptsUnhealthy alcohol useLong-term abstinenceAlcohol useContingency managementAlcohol consumptionFormal alcohol treatmentShort-term abstinenceMotivational enhancement therapyGOV IDENTIFIERSecondary outcomesWeek 24Primary outcomeWeek 12Preliminary efficacyTreatment trialsPhysician managementEfficacy trialsMedical conditionsAlcohol treatmentExploratory outcomesEnhancement therapyAbstinenceTrialsCareHealthy activitiesFactors Associated with Bothersome Symptoms in Individuals With and Without HIV Who Report Alcohol Use
Bahji A, Gordon K, Crystal S, Satre D, Wiliams E, Edelman E, Justice A. Factors Associated with Bothersome Symptoms in Individuals With and Without HIV Who Report Alcohol Use. AIDS And Behavior 2023, 27: 2455-2462. PMID: 36622487, PMCID: PMC10225332, DOI: 10.1007/s10461-022-03972-3.Peer-Reviewed Original ResearchPromoting alcohol treatment engagement post-hospitalization with brief intervention, medications and CBT4CBT: protocol for a randomized clinical trial in a diverse patient population
Edelman E, Rojas-Perez O, Nich C, Corvino J, Frankforter T, Gordon D, Jordan A, Paris, Jr M, Weimer M, Yates B, Williams E, Kiluk B. Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications and CBT4CBT: protocol for a randomized clinical trial in a diverse patient population. Addiction Science & Clinical Practice 2023, 18: 55. PMID: 37726823, PMCID: PMC10510167, DOI: 10.1186/s13722-023-00407-9.Peer-Reviewed Original ResearchConceptsPost-hospital dischargeCognitive behavioral therapySelf-reported alcohol useBrief Negotiation InterviewUse disordersAlcohol use outcomesComputer-based trainingDays post-hospital dischargeAlcohol use disorderBehavioral therapyInitiation of medicationHealth care utilizationHealth promotion advocatesTreatment engagementUse outcomesAlcohol useSecondary outcomesHospitalized patientsPrimary outcomeCare utilizationClinical trialsAcademic hospitalExploratory outcomesAUDProcess evaluation
2022
Cessation of self-reported opioid use and impacts on co-occurring health conditions
Scheidell J, Townsend T, Ban K, Caniglia E, Charles D, Edelman E, Marshall B, Gordon A, Justice A, Braithwaite R, Khan M. Cessation of self-reported opioid use and impacts on co-occurring health conditions. Drug And Alcohol Dependence 2022, 242: 109712. PMID: 36469994, PMCID: PMC10108375, DOI: 10.1016/j.drugalcdep.2022.109712.Peer-Reviewed Original ResearchConceptsOpioid useCocaine useSelf-reported opioid useBaseline opioid useCo-occurring health conditionsUnhealthy alcohol useEvidence-based interventionsLogistic regression modelsOpioid misusePrescription opioidsSelf-reported useReporting cannabisDepressive symptomsPainCannabis useAlcohol useHealth conditionsSubstance useSymptomsAnxiety symptomsSubsequent cessationCessationRegression modelsOutcomesParticipants
2012
Combining Rapid HIV Testing and a Brief Alcohol Intervention in Young Unhealthy Drinkers in the Emergency Department: A Pilot Study
Edelman EJ, Dinh A, Radulescu R, Lurie B, D'Onofrio G, Tetrault JM, Fiellin DA, Fiellin LE. Combining Rapid HIV Testing and a Brief Alcohol Intervention in Young Unhealthy Drinkers in the Emergency Department: A Pilot Study. The American Journal Of Drug And Alcohol Abuse 2012, 38: 539-543. PMID: 22794939, PMCID: PMC3522092, DOI: 10.3109/00952990.2012.701359.Peer-Reviewed Original ResearchConceptsSexual risk reduction counselingSexual risk behaviorsRisk reduction counselingRapid HIV testingEmergency departmentRisk behaviorsReduction counselingHIV testingAlcohol useUnhealthy drinkersAlcohol consumptionMean age 26 yearsAverage weekly drinksImportant preventive servicesAlcohol Use Disorders Identification Test (AUDIT) scoresUnknown HIV statusRapid HIV testsUnhealthy alcohol useAge 26 yearsBrief alcohol interventionHIV testHIV statusRegular doctorPreventive servicesRisk populations