Adaptive Mutations In RNA-Based Regulatory Mechanisms: Computational and Experimental Investigations
Barash D, Sikorski J, Perry E, Nevo E, Nudler E. Adaptive Mutations In RNA-Based Regulatory Mechanisms: Computational and Experimental Investigations. Israel Journal Of Ecology And Evolution 2006, 52: 263-279. DOI: 10.1560/ijee_52_3-4_263.Peer-Reviewed Original ResearchTPP riboswitchRegulatory mechanismsEvolution CanyonTermination efficiencyTranscription terminationNorth-facing slopesAdaptive mutationsEvolutionary time scalesGenetic control elementsRNA genetic control elementsBeneficial fitness effectsClass of RNAsMesic north-facing slopeParticipation of proteinsLevel of RNAModel systemOrganism's fitnessFitness effectsBeneficial mutationsTranslation initiationAncient originGC contentNonrandom mutationsPromoter regionMutational differences