2017
Sport, sex and age increase risk of illness at the Rio 2016 Summer Paralympic Games: a prospective cohort study of 51 198 athlete days
Derman W, Schwellnus MP, Jordaan E, Runciman P, Blauwet C, Webborn N, Lexell J, Van de Vliet P, Tuakli-Wosornu Y, Kissick J, Stomphorst J. Sport, sex and age increase risk of illness at the Rio 2016 Summer Paralympic Games: a prospective cohort study of 51 198 athlete days. British Journal Of Sports Medicine 2017, 52: 17. PMID: 29074477, DOI: 10.1136/bjsports-2017-097962.Peer-Reviewed Original ResearchConceptsRio 2016 Summer Paralympic GamesIllness incidence ratesAthlete daysSummer Paralympic GamesHigh riskOlder athletesOwn medical supportProspective cohort studyElectronic data capturing systemsEpidemiology of illnessRates of illnessIllness surveillance systemDigestive systemRisk of illnessCohort studyIncidence rateIncrease riskIllness dataIllnessRespiratory systemSubcutaneous systemFemale athletesWheelchair fencingData capturing systemMedical supportHigh precompetition injury rate dominates the injury profile at the Rio 2016 Summer Paralympic Games: a prospective cohort study of 51 198 athlete days
Derman W, Runciman P, Schwellnus M, Jordaan E, Blauwet C, Webborn N, Lexell J, van de Vliet P, Tuakli-Wosornu Y, Kissick J, Stomphorst J. High precompetition injury rate dominates the injury profile at the Rio 2016 Summer Paralympic Games: a prospective cohort study of 51 198 athlete days. British Journal Of Sports Medicine 2017, 52: 24. PMID: 29030389, DOI: 10.1136/bjsports-2017-098039.Peer-Reviewed Original ResearchConceptsInjury incidence ratesHighest injury incidence rateRio 2016 Summer Paralympic GamesAthlete daysSummer Paralympic GamesFootball 5Football 7Own medical supportIndependent risk factorProspective cohort studyAcute traumatic injuryInjury prevention programsCommon anatomical areaIncidence of injuryIllness surveillance systemCohort studyCommon injuriesRisk factorsIncidence rateInjury profileTraumatic injuryInjury ratesInjury dataInjuryPrevention programsReturn to Activities After Patellofemoral Arthroplasty.
Shubin Stein BE, Brady JM, Grawe B, Tuakli-Wosornu Y, Nguyen JT, Wolfe E, Voigt M, Mahony G, Strickland S. Return to Activities After Patellofemoral Arthroplasty. The American Journal Of Orthopedics 2017, 46: e353-e357. PMID: 29309448.Peer-Reviewed Original ResearchConceptsPatient-reported outcome measuresPatellofemoral arthroplastyOutcome measuresFunctional outcome scoresKnee arthroplasty outcomesActivity levelsPain reliefKnee functionOutcome scoresPatellofemoral arthritisArthroplasty outcomesImplant survivorshipConsecutive casesPatient satisfactionPatientsSurgeryArthroplastyHigh rateSame activity levelPreferred activitiesHigh levelsArthritisLevelsFindingsActivity
2016
Predictors of Exercise Adherence in Patients With Meniscal Tear and Osteoarthritis
Tuakli-Wosornu YA, Selzer F, Losina E, Katz JN. Predictors of Exercise Adherence in Patients With Meniscal Tear and Osteoarthritis. Archives Of Physical Medicine And Rehabilitation 2016, 97: 1945-1952. PMID: 27296899, PMCID: PMC5083166, DOI: 10.1016/j.apmr.2016.05.011.Peer-Reviewed Original ResearchConceptsPoor exercise adherenceMeniscal tearsExercise adherenceOsteoarthritis Research (MeTeOR) trialPrescribed home exerciseRisk of nonadherenceAbsence of painArthroscopic partial meniscectomyTimes greater riskLow incomeBaseline painReferral centerHome exercisesMETEOR trialPrimary outcomeExercise programOsteoarthritic changesPrescribed exercisePartial meniscectomyTreatment groupsPatientsOsteoarthritisSecondary analysisGreater riskMultivariate model
2012
Total hip and knee arthroplasty in patients with hereditary multiple exostoses.
Mesfin A, Goddard MS, Tuakli-Wosornu YA, Khanuja HS. Total hip and knee arthroplasty in patients with hereditary multiple exostoses. Orthopedics 2012, 35: e1807-10. PMID: 23218641, DOI: 10.3928/01477447-20121120-29.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyHereditary multiple exostosesTotal knee arthroplastyBony deformityHip arthroplastyMultiple exostosesKnee deformityTotal hipKnee arthroplastyValgus deformityMalignant transformationCoxa valga deformityPrevious reconstructive surgeryValgus knee deformityLimb length discrepancyBone scanPathologic evaluationSuch patientsSurgical treatmentPediatric populationSurgical managementPainful lesionsPatient populationTotal kneeDeformity correction
2006
Molecular Characterization of Loss-of-Function Mutations in PCSK9 and Identification of a Compound Heterozygote
Zhao Z, Tuakli-Wosornu Y, Lagace TA, Kinch L, Grishin NV, Horton JD, Cohen JC, Hobbs HH. Molecular Characterization of Loss-of-Function Mutations in PCSK9 and Identification of a Compound Heterozygote. American Journal Of Human Genetics 2006, 79: 514-523. PMID: 16909389, PMCID: PMC1559532, DOI: 10.1086/507488.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAmino Acid SequenceCells, CulturedChild, PreschoolCholesterol, LDLFemaleHeterozygoteHumansImmunoprecipitationMaleMiddle AgedModels, MolecularMolecular Sequence DataMutation, MissensePedigreeProprotein Convertase 9Proprotein ConvertasesProtein ConformationProtein FoldingProtein TransportRecombinant ProteinsSerine EndopeptidasesConceptsProprotein convertase subtilisin/kexin type 9Low plasma levelsPlasma levelsLevels of PCSK9Function mutationsLow-density lipoprotein cholesterolConvertase subtilisin/kexin type 9Subtilisin/kexin type 9LDL-lowering therapyCoronary heart diseaseDevelopment of atherosclerosisApparent good healthCompound heterozygotesWild-type PCSK9Immunoblotting of plasmaLipoprotein cholesterolHeart diseasePCSK9 secretionType 9Confer protectionLDLGood healthElevated levelsSevere lossAttractive target