Exposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study.
Ding E, Deng F, Fang J, Liu J, Yan W, Yao Q, Miao K, Wang Y, Sun P, Li C, Liu Y, Dong H, Dong L, Zhang X, Lu Y, Lin X, Ding C, Li T, Shi Y, Cai Y, Liu X, Godri Pollitt K, Ji J, Tong S, Tang S, Shi X. Exposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study. Environmental Health Perspectives 2024, 132: 97005. PMID: 39240788, PMCID: PMC11379127, DOI: 10.1289/ehp13864.Peer-Reviewed Original ResearchConceptsDyslipidemia markersCardiovascular diseaseMulti-omicsMarkers of dyslipidemiaExamination of cytokinesMeasurement of cytokinesSerum lipidomeSystemic inflammationMulti-omics profilingCardiac functionDyslipidemiaPrimary preventionClinical measuresSerumChinese adultsBlood transcriptomeImpact spectraCytokinesExposome-wide association studyInflammationMarkersBiomolecular pathwaysAssociationHealthy older adultsElectrocardiogramAssociation between dietary diversity changes and frailty among Chinese older adults: findings from a nationwide cohort study
Wang X, Zhong W, Zhang Y, Xiang J, Chen H, Li Z, Shen Q, Shen D, Song W, Fu Q, Gao J, Chen Z, Li C, Xie J, Liu D, Lv Y, Shi X, Mao C. Association between dietary diversity changes and frailty among Chinese older adults: findings from a nationwide cohort study. Nutrition Journal 2024, 23: 91. PMID: 39138490, PMCID: PMC11320915, DOI: 10.1186/s12937-024-00997-3.Peer-Reviewed Original ResearchConceptsDietary diversity scoreRisk of frailtyChinese older adultsOlder adultsSelf-reported health itemsChinese Longitudinal Healthy Longevity SurveyHigher risk of frailtyIncreased risk of frailtyOlder Chinese adultsFollow-up surveyNationwide cohort studyCox proportional hazards modelsHealth itemsLongevity SurveyFrailty incidencePrevent frailtyProportional hazards modelBackgroundDietary diversityChinese adultsFood groupsAssess frailtyPotential preventive measuresDiversity scoreComparing scoresCohort studyAssociation between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study
Sun P, Guo X, Ding E, Li C, Ren H, Xu Y, Qian J, Deng F, Shi W, Dong H, Lin E, Guo P, Fang J, Zhang Q, Zhao W, Tong S, Lu X, Pollitt K, Shi X, Tang S. Association between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study. Environmental Health Perspectives 2024, 132: 077005. PMID: 39028628, PMCID: PMC11259245, DOI: 10.1289/ehp13865.Peer-Reviewed Original ResearchConceptsFat mass indicatorsHealthy older adultsBayesian kernel machine regressionVisceral fat areaOlder adultsPercent body fatBody compositionBody fat massExposome-wide association studyPrevention of chronic diseasesAir pollution exposureBody composition indicatorsMediation analysisInBody 770 deviceHealthy adultsAssociated with increased body fat massBody composition changesKernel machine regressionBayesian kernel machine regression modelsChronic diseasesPollution exposureBody fatAssociation studiesAdverse health effectsFat area[Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China].
Zhou J, Qi L, Wang J, Liu S, Shi W, Ye L, Zhang Z, Zhang Z, Meng X, Cui J, Chen C, Lyu Y, Shi X. [Prediction model related to 6-year risk of frailty in older adults aged 65 years or above in China]. Chinese Journal Of Epidemiology 2024, 45: 809-816. PMID: 38889980, DOI: 10.3760/cma.j.cn112338-20231205-00333.Peer-Reviewed Original ResearchConceptsDaily living scoresPredictors of frailtyArea under the receiver operating characteristic curveIncident frailtyOlder adultsLiving scoresChinese Longitudinal Healthy Longevity SurveyRisk thresholdSelf-rated healthChinese older adultsRisk of incident frailtyRisk of frailtyFree of frailtyPhysical examination variablesCox proportional hazards regression modelsProportional hazards regression modelsRisk prediction modelInstrumental activitiesHazards regression modelsLongevity SurveyFrailty incidenceFollow-up timeDecision-curve analysisOlder personsReceiver operating characteristic curve[Exploring implementation strategies for healthy longevity among the elderly population in China based on the delphi method].
Chai X, Cui J, Ye L, Lyu Y, Shao R, Zhang J, Shi X. [Exploring implementation strategies for healthy longevity among the elderly population in China based on the delphi method]. Chinese Preventive Medicine 2024, 58: 883-890. PMID: 38955737, DOI: 10.3760/cma.j.cn112150-20230804-00056.Peer-Reviewed Original ResearchConceptsHarmony coefficientsImplementation strategiesHealthy longevityAuthority coefficientPromote healthy longevityExpert active coefficientElderly populationChinese elderly populationDelphi methodDelphi consultationConsultation questionnaireElderly care service industryPublic healthFeasibility scoreScore of feasibilityAverage scoreConsultationExpert discussionScoresLiterature reviewClinical medicine[Exploring a definition of healthy longevity in Chinese population based on Delphi method].
Chai X, Cui J, Ye L, Zhou J, Shao R, Shi X, Lyu Y, Zhang J. [Exploring a definition of healthy longevity in Chinese population based on Delphi method]. Chinese Preventive Medicine 2024, 58: 629-635. PMID: 38715502, DOI: 10.3760/cma.j.cn112150-20230924-00220.Peer-Reviewed Original ResearchConceptsHealthy longevityMental healthNon-communicable disease indicatorsSelf-rated healthTwo-round Delphi consultationCognitive functionWell-beingChinese populationFunctions of daily lifeHigh disability rateSubjective well-beingGeriatric healthDelphi consultationPhysical healthFunctional abilityHearing functionElderly care service industryDelphi surveyExpert consultationDisability rateHealthPublic healthMeasurement toolsMultiple-choice questionsFamily members[Association of urinary cadmium level with body mass index and body circumferences among older adults over 65 years old in 9 longevity areas of China].
Zhang Z, Wu B, Qu Y, Li Y, Xu L, Lyu C, Chen C, Wang J, Xue K, Wei Y, Zhou J, Zheng X, Qiu Y, Luo Y, Liu J, Lyu Y, Shi X. [Association of urinary cadmium level with body mass index and body circumferences among older adults over 65 years old in 9 longevity areas of China]. Chinese Preventive Medicine 2024, 58: 227-234. PMID: 38387955, DOI: 10.3760/cma.j.cn112150-20230912-00181.Peer-Reviewed Original ResearchConceptsBody mass indexWaist circumferenceHip circumferenceCalf circumferenceOlder adultsBody circumferencesLongevity areasUrinary cadmium levelsLinear regression modelsMultiple linear regression modelUrinary cadmium concentrationCadmium levelsUrinary cadmiumAssociated with decreased BMIChange of body mass indexCadmium concentrationsRegression modelsSocio-demographic characteristicsRestricted cubic spline curvesRestricted cubic splinesAge of subjectsBiomarkers Cohort StudyHealth statusNegative linear associationWaist[Association of lifestyle and apolipoprotein E gene with risk for cognitive frailty in elderly population in China].
Zhong W, Wang X, Song W, Li C, Chen H, Chen Z, Lyu Y, Li Z, Shi X, Mao C. [Association of lifestyle and apolipoprotein E gene with risk for cognitive frailty in elderly population in China]. Chinese Journal Of Epidemiology 2024, 45: 41-47. PMID: 38228523, DOI: 10.3760/cma.j.cn112338-20231027-00254.Peer-Reviewed Original ResearchConceptsCognitive frailtyCox proportional hazards regression modelsProportional hazards regression modelsPhysical activityHazards regression modelsHealthy lifestyleLevels of physical activityChinese Longitudinal Healthy Longevity SurveyElderly populationRegular physical activityDietary diversityLevel of dietary diversityAssociation of lifestyleAPOE geneImpact of lifestyleRegression modelsAdditive interactionAPOE e4 alleleLifestyle scoreCombined lifestyleLongevity SurveyPhysical frailtyStudy participantsElderly personsLifestyle[Association of sleep duration and physical exercise with dyslipidemia in older adults aged 80 years and over in China].
Wu B, Li Y, Xu L, Zhang Z, Zhou J, Wei Y, Chen C, Wang J, Wu C, Li Z, Hu Z, Long F, Wu Y, Hu X, Li K, Li F, Luo Y, Liu Y, Lyu Y, Shi X. [Association of sleep duration and physical exercise with dyslipidemia in older adults aged 80 years and over in China]. Chinese Journal Of Epidemiology 2024, 45: 48-55. PMID: 38228524, DOI: 10.3760/cma.j.cn112338-20231007-00207.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesPhysical exerciseSleep durationPerson yearsDose-response relationshipAssociation of sleep durationPositive dose-response relationshipImpact of sleep durationBlood lipid testRisk of dyslipidemiaAverage sleep durationRestricted cubic spline functionsCompeting risk modelBaseline surveyBiomarkers Cohort StudyCases of dyslipidemiaLipid testingFasting venous blood samplesInteraction of sleep durationCohort studyExerciseCompetitive risk model analysisDemographic characteristicsIncidence densityStudy subjectsVitamin B12 is associated negatively with anemia in older Chinese adults with a low dietary diversity level: evidence from the Healthy Ageing and Biomarkers Cohort Study (HABCS)
Liu L, Zhou J, Chen C, Qu Y, Wang J, Lu F, Liu Y, Cai J, Ji S, Li Y, Gu H, Zhao F, Lyu Y, Shi X. Vitamin B12 is associated negatively with anemia in older Chinese adults with a low dietary diversity level: evidence from the Healthy Ageing and Biomarkers Cohort Study (HABCS). BMC Geriatrics 2024, 24: 18. PMID: 38178043, PMCID: PMC10768404, DOI: 10.1186/s12877-023-04586-7.Peer-Reviewed Original ResearchConceptsVitamin B12 levelsDietary diversity scorePlasma vitamin B12 levelsB12 levelsFood frequency questionnaireDifferent dietary patternsOlder adultsFrequency questionnaireDietary patternsHigh vitamin B12 levelsVitamin B12Low dietary diversity scoreHigh dietary diversity scorePrevalence of anemiaElderly Chinese peopleBiomarker cohort studyOlder Chinese adultsCohort studyAnemia statusDecreased riskMean ageAnemiaChinese adultsConclusionThe relationshipConfounding factors